메뉴 건너뛰기




Volumn 13, Issue 10, 2009, Pages 4205-4218

Combination of taxol and Bcl-2 siRNA induces apoptosis in human glioblastoma cells and inhibits invasion, angiogenesis and tumour growth

Author keywords

Angiogenesis; Apoptosis; Bcl 2 siRNA; Cell invasion; Glioblastoma; Taxol

Indexed keywords

CASPASE 3; CASPASE 9; MESSENGER RNA; PACLITAXEL; PROTEIN BCL 2; SMALL INTERFERING RNA;

EID: 73149094257     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1582-4934.2008.00539.x     Document Type: Article
Times cited : (34)

References (32)
  • 1
    • 25144436834 scopus 로고    scopus 로고
    • Gene therapy for malignant glioma: current clinical status
    • Pulkkanen KJ, Yla-Herttuala S. Gene therapy for malignant glioma: current clinical status. Mol Ther. 2005, 12:585-98.
    • (2005) Mol Ther. , vol.12 , pp. 585-598
    • Pulkkanen, K.J.1    Yla-Herttuala, S.2
  • 2
    • 33644850759 scopus 로고    scopus 로고
    • Advances toward an understanding of brainstem gliomas
    • Donaldson SS, Laningham F, Fisher PG. Advances toward an understanding of brainstem gliomas. J Clin Oncol. 2006, 24:1266-72.
    • (2006) J Clin Oncol. , vol.24 , pp. 1266-1272
    • Donaldson, S.S.1    Laningham, F.2    Fisher, P.G.3
  • 3
    • 0036488589 scopus 로고    scopus 로고
    • Role of integrins in cell invasion and migration
    • Hood JD, Cheresh DA. Role of integrins in cell invasion and migration. Nat Rev Cancer. 2002, 2:91-100.
    • (2002) Nat Rev Cancer. , vol.2 , pp. 91-100
    • Hood, J.D.1    Cheresh, D.A.2
  • 4
    • 0033766009 scopus 로고    scopus 로고
    • Molecular events implicated in brain tumor angiogenesis and invasion
    • Zagzag D, Friedlander DR, Margolis B. Molecular events implicated in brain tumor angiogenesis and invasion. Pediatr Neurosurg. 2000, 33:49-55.
    • (2000) Pediatr Neurosurg. , vol.33 , pp. 49-55
    • Zagzag, D.1    Friedlander, D.R.2    Margolis, B.3    et al4
  • 5
    • 0037071388 scopus 로고    scopus 로고
    • Dysregulation of apoptosis genes in hematopoietic malignancies
    • Kitada S, Pedersen IM, Schimmer AD. Dysregulation of apoptosis genes in hematopoietic malignancies. Oncogene. 2002, 21:3459-74.
    • (2002) Oncogene. , vol.21 , pp. 3459-3474
    • Kitada, S.1    Pedersen, I.M.2    Schimmer, A.D.3    et al4
  • 6
    • 58149466870 scopus 로고    scopus 로고
    • Bcl-2 siRNA augments taxol mediated apoptotic death in human glioblastoma U138MG and U251MG cells
    • George J, Banik NL, Ray SK. Bcl-2 siRNA augments taxol mediated apoptotic death in human glioblastoma U138MG and U251MG cells. Neurochem Res. 2009, 34:66-78.
    • (2009) Neurochem Res. , vol.34 , pp. 66-78
    • George, J.1    Banik, N.L.2    Ray, S.K.3
  • 7
    • 0033760783 scopus 로고    scopus 로고
    • Bcl-2 protects neuronal cells against taxol-induced apoptosis by inducing multi-nucleation
    • Nuydens R, Dispersyn G, Van Den Kieboom G. Bcl-2 protects neuronal cells against taxol-induced apoptosis by inducing multi-nucleation. Apoptosis. 2000, 5:335-43.
    • (2000) Apoptosis. , vol.5 , pp. 335-343
    • Nuydens, R.1    Dispersyn, G.2    Van Den Kieboom, G.3    et al4
  • 8
    • 2442534189 scopus 로고    scopus 로고
    • Induction of survivin expression by taxol (paclitaxel) is an early event, which is independent of taxol-mediated G2/M arrest
    • Ling X, Bernacki RJ, Brattain MG. Induction of survivin expression by taxol (paclitaxel) is an early event, which is independent of taxol-mediated G2/M arrest. J Biol Chem. 2004, 279:15196-203.
    • (2004) J Biol Chem. , vol.279 , pp. 15196-15203
    • Ling, X.1    Bernacki, R.J.2    Brattain, M.G.3    et al4
  • 9
    • 33847398220 scopus 로고    scopus 로고
    • Evaluation of the tubulin-bound paclitaxel conformation: synthesis, biology, and SAR studies of C-4 to C-3′ bridged paclitaxel analogues
    • Ganesh T, Yang C, Norris A. Evaluation of the tubulin-bound paclitaxel conformation: synthesis, biology, and SAR studies of C-4 to C-3′ bridged paclitaxel analogues. J Med Chem. 2007, 50:713-25.
    • (2007) J Med Chem. , vol.50 , pp. 713-725
    • Ganesh, T.1    Yang, C.2    Norris, A.3    et al4
  • 10
    • 0036184739 scopus 로고    scopus 로고
    • Paclitaxel triggers cell death primarily via caspase-independent routes in the non-small cell lung cancer cell line NCI-H460
    • Huisman C, Ferreira CG, Broker LE. Paclitaxel triggers cell death primarily via caspase-independent routes in the non-small cell lung cancer cell line NCI-H460. Clin Cancer Res. 2002, 8:596-606.
    • (2002) Clin Cancer Res. , vol.8 , pp. 596-606
    • Huisman, C.1    Ferreira, C.G.2    Broker, L.E.3    et al4
  • 11
    • 34248179500 scopus 로고    scopus 로고
    • SiRNA-mediated knockdown of connective tissue growth factor prevents N-nitrosodimethylamine-induced hepatic fibrosis in rats
    • George J, Tsutsumi M. siRNA-mediated knockdown of connective tissue growth factor prevents N-nitrosodimethylamine-induced hepatic fibrosis in rats. Gene Ther. 2007, 14:790-803.
    • (2007) Gene Ther. , vol.14 , pp. 790-803
    • George, J.1    Tsutsumi, M.2
  • 12
    • 33847642071 scopus 로고    scopus 로고
    • Bcl-2 protects against hyperoxia-induced apoptosis through inhibition of the mitochondria-dependent pathway
    • Metrailler-Ruchonnet I, Pagano A, Carnesecchi S. Bcl-2 protects against hyperoxia-induced apoptosis through inhibition of the mitochondria-dependent pathway. Free Radic Biol Med. 2007, 42:1062-74.
    • (2007) Free Radic Biol Med. , vol.42 , pp. 1062-1074
    • Metrailler-Ruchonnet, I.1    Pagano, A.2    Carnesecchi, S.3    et al4
  • 13
    • 0034059440 scopus 로고    scopus 로고
    • Bcl-2 inhibits Bax translocation from cytosol to mitochondria during drug-induced apoptosis of human tumor cells
    • Murphy KM, Ranganathan V, Farnsworth ML. Bcl-2 inhibits Bax translocation from cytosol to mitochondria during drug-induced apoptosis of human tumor cells. Cell Death Differ. 2000, 7:102-111.
    • (2000) Cell Death Differ. , vol.7 , pp. 102-111
    • Murphy, K.M.1    Ranganathan, V.2    Farnsworth, M.L.3    et al4
  • 14
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays
    • Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods. 1983, 65:55-63.
    • (1983) J Immunol Methods. , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 15
    • 38449096784 scopus 로고    scopus 로고
    • In vitro matrigel fibroblast invasion assay
    • Tolboom TC, Huizinga TW. In vitro matrigel fibroblast invasion assay. Methods Mol Med. 2007, 135:413-22.
    • (2007) Methods Mol Med. , vol.135 , pp. 413-422
    • Tolboom, T.C.1    Huizinga, T.W.2
  • 16
    • 43049114500 scopus 로고    scopus 로고
    • Dorsal skinfold chamber preparation in mice - studying angiogenesis by intravital microscopy
    • Murray JC. In, editor, Totowa, New Jersey, Humana Press, pp.
    • Sckell A, Leunig M. Dorsal skinfold chamber preparation in mice - studying angiogenesis by intravital microscopy. Methods in molecular medicine - angiogenesis protocols 2001, Vol. 46:95-105. Murray JC, In, editor, Totowa, New Jersey, Humana Press, pp.
    • (2001) Methods in molecular medicine - angiogenesis protocols , vol.46 , pp. 95-105
    • Sckell, A.1    Leunig, M.2
  • 17
    • 12244296444 scopus 로고    scopus 로고
    • Effect of the tumor vascular-damaging agent, ZD6126, on the radioresponse of U87 glioblastoma
    • Wachsberger PR, Burd R, Marero N. Effect of the tumor vascular-damaging agent, ZD6126, on the radioresponse of U87 glioblastoma. Clin Cancer Res. 2005, 11:835-42.
    • (2005) Clin Cancer Res. , vol.11 , pp. 835-842
    • Wachsberger, P.R.1    Burd, R.2    Marero, N.3    et al4
  • 18
    • 0034714203 scopus 로고    scopus 로고
    • Molecular recognition of taxol by microtubules. Kinetics and thermodynamics of binding of fluorescent taxol derivatives to an exposed site
    • Díaz JF, Strobe R, Engelborghs Y. Molecular recognition of taxol by microtubules. Kinetics and thermodynamics of binding of fluorescent taxol derivatives to an exposed site. J Biol Chem. 2000, 275:26265-76.
    • (2000) J Biol Chem. , vol.275 , pp. 26265-26276
    • Díaz, J.F.1    Strobe, R.2    Engelborghs, Y.3    et al4
  • 19
    • 3042836538 scopus 로고    scopus 로고
    • The bioactive Taxol conformation on β-tubulin: experimental evidence from highly active constrained analogs
    • Ganesh T, Guza RC, Bane S. The bioactive Taxol conformation on β-tubulin: experimental evidence from highly active constrained analogs. Proc Natl Acad Sci USA. 2004, 101:10006-11.
    • (2004) Proc Natl Acad Sci USA. , vol.101 , pp. 10006-10011
    • Ganesh, T.1    Guza, R.C.2    Bane, S.3    et al4
  • 20
    • 34250781209 scopus 로고    scopus 로고
    • Restoration of tissue factor pathway inhibitor-2 in a human glioblastoma cell line triggers caspase-mediated pathway and apoptosis
    • George J, Gondi CS, Dinh DH. Restoration of tissue factor pathway inhibitor-2 in a human glioblastoma cell line triggers caspase-mediated pathway and apoptosis. Clin Cancer Res. 2007, 13:3507-17.
    • (2007) Clin Cancer Res. , vol.13 , pp. 3507-3517
    • George, J.1    Gondi, C.S.2    Dinh, D.H.3    et al4
  • 21
    • 38749131581 scopus 로고    scopus 로고
    • Combination of all-trans retinoic acid and paclitaxel-induced differentiation and apoptosis in human glioblastoma U87MG xenografts in nude mice
    • Karmakar S, Banik NL, Ray SK. Combination of all-trans retinoic acid and paclitaxel-induced differentiation and apoptosis in human glioblastoma U87MG xenografts in nude mice. Cancer. 2008, 112:596-607.
    • (2008) Cancer. , vol.112 , pp. 596-607
    • Karmakar, S.1    Banik, N.L.2    Ray, S.K.3
  • 22
    • 1642482625 scopus 로고    scopus 로고
    • Small interfering RNA targeting bcl-2 sensitizes malignant melanoma
    • Wacheck V, Losert D, Günsberg P. Small interfering RNA targeting bcl-2 sensitizes malignant melanoma. Oligonucleotides. 2003, 13:393-400.
    • (2003) Oligonucleotides. , vol.13 , pp. 393-400
    • Wacheck, V.1    Losert, D.2    Günsberg, P.3    et al4
  • 23
    • 2342538514 scopus 로고    scopus 로고
    • Specific downregulation of bcl-2 and XIAP by RNAi enhances the effects of chemotherapeutic agents in MCF-7 human breast cancer cells
    • Lima RT, Martins LM, Guimarães JE. Specific downregulation of bcl-2 and XIAP by RNAi enhances the effects of chemotherapeutic agents in MCF-7 human breast cancer cells. Cancer Gene Ther. 2004, 11:309-16.
    • (2004) Cancer Gene Ther. , vol.11 , pp. 309-316
    • Lima, R.T.1    Martins, L.M.2    Guimarães, J.E.3    et al4
  • 27
    • 0037699954 scopus 로고    scopus 로고
    • The biology of VEGF and its receptors
    • Ferrara N, Gerber HP, LeCouter J. The biology of VEGF and its receptors. Nat Med. 2003, 9:669-76.
    • (2003) Nat Med. , vol.9 , pp. 669-676
    • Ferrara, N.1    Gerber, H.P.2    LeCouter, J.3
  • 29
    • 0742304114 scopus 로고    scopus 로고
    • Evaluation of the antiangiogenic effect of taxol in a human epithelial ovarian carcinoma cell line
    • Hata K, Osaki M, Dhar DK. Evaluation of the antiangiogenic effect of taxol in a human epithelial ovarian carcinoma cell line. Cancer Chemother Pharmacol. 2004, 53:68-74.
    • (2004) Cancer Chemother Pharmacol. , vol.53 , pp. 68-74
    • Hata, K.1    Osaki, M.2    Dhar, D.K.3    et al4
  • 30
    • 33947614806 scopus 로고    scopus 로고
    • SiRNA-mediated Bcl-2 and Bcl-xL gene silencing sensitizes human hepatoblastoma cells to chemotherapeutic drugs
    • Lei XY, Zhong M, Feng LF. siRNA-mediated Bcl-2 and Bcl-xL gene silencing sensitizes human hepatoblastoma cells to chemotherapeutic drugs. Clin Exp Pharmacol Physiol. 2007, 34:450-6.
    • (2007) Clin Exp Pharmacol Physiol. , vol.34 , pp. 450-456
    • Lei, X.Y.1    Zhong, M.2    Feng, L.F.3    et al4
  • 31
    • 34547134691 scopus 로고    scopus 로고
    • Intraperitoneal injection of a hairpin RNA-expressing plasmid targeting urokinase-type plasminogen activator (uPA) receptor and uPA retards angiogenesis and inhibits intracranial tumor growth in nude mice
    • Gondi CS, Lakka SS, Dinh DH. Intraperitoneal injection of a hairpin RNA-expressing plasmid targeting urokinase-type plasminogen activator (uPA) receptor and uPA retards angiogenesis and inhibits intracranial tumor growth in nude mice. Clin Cancer Res. 2007, 13:4051-60.
    • (2007) Clin Cancer Res. , vol.13 , pp. 4051-4060
    • Gondi, C.S.1    Lakka, S.S.2    Dinh, D.H.3    et al4
  • 32
    • 34547582307 scopus 로고    scopus 로고
    • Effectiveness of siRNA uptake in target tissues by various delivery methods
    • Larson SD, Jackson LN, Chen LA. Effectiveness of siRNA uptake in target tissues by various delivery methods. Surgery. 2007, 142:262-9.
    • (2007) Surgery. , vol.142 , pp. 262-269
    • Larson, S.D.1    Jackson, L.N.2    Chen, L.A.3    et al4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.