메뉴 건너뛰기




Volumn 2013, Issue , 2013, Pages

Effects of growth hormone replacement therapy on bone mineral density in growth hormone deficient adults: A meta-analysis

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE; SOMATOMEDIN C;

EID: 84877279398     PISSN: 16878337     EISSN: 16878345     Source Type: Journal    
DOI: 10.1155/2013/216107     Document Type: Article
Times cited : (17)

References (56)
  • 1
    • 0242659157 scopus 로고    scopus 로고
    • Growth hormone replacement for adult growth hormone deficiency
    • DOI 10.1517/14656566.4.11.1977
    • Shimon I., Growth hormone replacement for adult growth hormone deficiency. Expert Opinion on Pharmacotherapy 2003 4 11 1977 1983 2-s2.0-0242659157 10.1517/14656566.4.11.1977 (Pubitemid 37408109)
    • (2003) Expert Opinion on Pharmacotherapy , vol.4 , Issue.11 , pp. 1977-1983
    • Shimon, I.1
  • 2
    • 0023857232 scopus 로고
    • Growth hormone dependent stimulation of osteoblast-like cells in serum-free cultures via local synthesis of insulin-like growth factor I
    • Ernst M., Froesch E. R., Growth hormone dependent stimulation of osteoblast-like cells in serum-free cultures via local synthesis of insulin-like growth factor I. Biochemical and Biophysical Research Communications 1988 151 1 142 147 2-s2.0-0023857232 (Pubitemid 18074155)
    • (1988) Biochemical and Biophysical Research Communications , vol.151 , Issue.1 , pp. 142-147
    • Ernst, M.1    Froesch, E.R.2
  • 3
    • 84867429651 scopus 로고    scopus 로고
    • MSM enhances GH signaling via the Jak2/STAT5b pathway in osteoblast-like cells and osteoblast differentiation through the activation of STAT5b in MSCs
    • e47477
    • Joung Y. H., Lim E. J., Darvin P., Chung S. C., Jang J. W., Do Park K., Lee H. K., Kim H. S., Park T., Yang Y. M., MSM enhances GH signaling via the Jak2/STAT5b pathway in osteoblast-like cells and osteoblast differentiation through the activation of STAT5b in MSCs. PLoS One 2012 7 10 e47477
    • (2012) PLoS One , vol.7 , Issue.10
    • Joung, Y.H.1    Lim, E.J.2    Darvin, P.3    Chung, S.C.4    Jang, J.W.5    Do Park, K.6    Lee, H.K.7    Kim, H.S.8    Park, T.9    Yang, Y.M.10
  • 5
    • 84866483009 scopus 로고    scopus 로고
    • Quality of life in children and adolescents with growth hormone deficiency: Association with growth hormone treatment
    • 10.1159/000341151
    • Geisler A., Lass N., Reinsch N., Uysal Y., Singer V., Ravens-Sieberer U., Reinehr T., Quality of life in children and adolescents with growth hormone deficiency: association with growth hormone treatment. Hormone Research in Paediatrics 2012 78 2 94 99 10.1159/000341151
    • (2012) Hormone Research in Paediatrics , vol.78 , Issue.2 , pp. 94-99
    • Geisler, A.1    Lass, N.2    Reinsch, N.3    Uysal, Y.4    Singer, V.5    Ravens-Sieberer, U.6    Reinehr, T.7
  • 6
    • 0031747438 scopus 로고    scopus 로고
    • Effect of long-term treatment with GH on bone metabolism, bone mineral density and bone elasticity in GH-deficient adults
    • DOI 10.1046/j.1365-2265.1998.00439.x
    • Kann P., Piepkorn B., Schehler B., Andreas J., Lotz J., Prellwitz W., Beyer J., Effect of long-term treatment with GH on bone metabolism, bone mineral density and bone elasticity in GH-deficient adults. Clinical Endocrinology 1998 48 5 561 568 2-s2.0-0031747438 10.1046/j.1365-2265.1998.00439.x (Pubitemid 28252992)
    • (1998) Clinical Endocrinology , vol.48 , Issue.5 , pp. 561-568
    • Kann, P.1    Piepkorn, B.2    Schehler, B.3    Andreas, J.4    Lotz, J.5    Prellwitz, W.6    Beyer, J.7
  • 7
    • 84865727354 scopus 로고    scopus 로고
    • A longer interval without GH replacement and female gender are associated with lower bone mineral density in adults with childhood-onset GH deficiency: A KIMS database analysis
    • 10.1530/EJE-12-0070
    • Tritos N. A., Hamrahian A. H., King D., Greenspan S. L., Cook D. M., Jonsson P. J., Wajnrajch M. P., Koltowska-Haggstrom M., Biller B. M., A longer interval without GH replacement and female gender are associated with lower bone mineral density in adults with childhood-onset GH deficiency: a KIMS database analysis. European Journal of Endocrinology 2012 167 3 343 351 10.1530/EJE-12-0070
    • (2012) European Journal of Endocrinology , vol.167 , Issue.3 , pp. 343-351
    • Tritos, N.A.1    Hamrahian, A.H.2    King, D.3    Greenspan, S.L.4    Cook, D.M.5    Jonsson, P.J.6    Wajnrajch, M.P.7    Koltowska-Haggstrom, M.8    Biller, B.M.9
  • 9
    • 0030882291 scopus 로고    scopus 로고
    • Increased fracture frequency in adult patients with hypopituitarism and GH deficiency
    • DOI 10.1530/eje.0.1370240
    • Rosén T., Wilhelmsen L., Landin-Wilhelmsen K., Lappas G., Bengtsson B. Å., Increased fracture frequency in adult patients with hypopituitarism and GH deficiency. European Journal of Endocrinology 1997 137 3 240 245 2-s2.0-0030882291 10.1530/eje.0.1370240 (Pubitemid 27405107)
    • (1997) European Journal of Endocrinology , vol.137 , Issue.3 , pp. 240-245
    • Rosen, T.1    Wilhelmsen, L.2    Landin-Wilhelmsen, K.3    Lappas, G.4    Bengtsson, B.-A.5
  • 10
    • 44349107604 scopus 로고    scopus 로고
    • Comparative results of a 4-year study on cardiovascular parameters, lipid metabolism, body composition and bone mass between untreated and treated adult growth hormone deficient patients
    • DOI 10.1016/j.ghir.2008.01.002, PII S1096637408000038
    • Fideleff H. L., Boquete H. R., Stalldecker G., Giaccio A. V., Sobrado P. G. V., Comparative results of a 4-year study on cardiovascular parameters, lipid metabolism, body composition and bone mass between untreated and treated adult growth hormone deficient patients. Growth Hormone and IGF Research 2008 18 4 318 324 2-s2.0-44349107604 10.1016/j.ghir.2008.01.002 (Pubitemid 351729191)
    • (2008) Growth Hormone and IGF Research , vol.18 , Issue.4 , pp. 318-324
    • Fideleff, H.L.1    Boquete, H.R.2    Stalldecker, G.3    Giaccio, A.V.4    Sobrado, P.G.V.5
  • 12
    • 0037932676 scopus 로고    scopus 로고
    • Bone mineral density in adult patients with Turner's syndrome: Analyses of the effectiveness of GH and ovarian steroid hormone replacement therapies
    • DOI 10.1507/endocrj.50.263
    • Suganuma N., Furuhashi M., Hirooka T., Moriwaki T., Hasegawa Y., Mori O., Ogawa M., Bone mineral density in adult patients with Turner's syndrome: analyses of the effectiveness of GH and ovarian steroid hormone replacement therapies. Endocrine Journal 2003 50 3 263 269 2-s2.0-0037932676 10.1507/endocrj.50.263 (Pubitemid 36830002)
    • (2003) Endocrine Journal , vol.50 , Issue.3 , pp. 263-269
    • Suganuma, N.1    Furuhashi, M.2    Hirooka, T.3    Moriwaki, T.4    Hasegawa, Y.5    Mori, O.6    Ogawa, M.7
  • 13
    • 0029821102 scopus 로고    scopus 로고
    • Effects of 12 months of growth hormone (GH) treatment on calciotropic hormones, calcium homeostasis, and bone metabolism in adults with acquired GH deficiency: A double blind, randomized, placebo-controlled study
    • DOI 10.1210/jc.81.9.3352
    • Hansen T. B., Brixen K., Vahl N., Jørgensen J. O. L., Christiansen J. S., Mosekilde L., Hagen C., Effects of 12 months of growth hormone (GH) treatment on calciotropic hormones, calcium homeostasis, and bone metabolism in adults with acquired GH deficiency: a double blind, randomized, placebo-controlled study. Journal of Clinical Endocrinology and Metabolism 1996 81 9 3352 3359 2-s2.0-0029821102 10.1210/jc.81.9.3352 (Pubitemid 26296215)
    • (1996) Journal of Clinical Endocrinology and Metabolism , vol.81 , Issue.9 , pp. 3352-3359
    • Hansen, T.B.1    Brixen, K.2    Vahl, N.3    Jorgensen, J.O.L.4    Christiansen, J.S.5    Mosekilde, L.6    Hagen, C.7
  • 14
    • 0029812889 scopus 로고    scopus 로고
    • Two years of growth hormone (GH) treatment increases bone mineral content and density in hypopituitary patients with adult-onset GH deficiency
    • DOI 10.1210/jc.81.8.2865
    • Johannsson G., Rosén T., Bosaeus I., Sjöström L., Bengtsson B. Å., Two years of growth hormone (GH) treatment increases bone mineral content and density in hypopituitary patients with adult-onset GH deficiency. Journal of Clinical Endocrinology and Metabolism 1996 81 8 2865 2873 2-s2.0-0029812889 10.1210/jc.81.8.2865 (Pubitemid 26323877)
    • (1996) Journal of Clinical Endocrinology and Metabolism , vol.81 , Issue.8 , pp. 2865-2873
    • Johannsson, G.1    Rosen, T.2    Bosaeus, I.3    Sjostrom, L.4    Bengtsson, B.-A.5
  • 15
    • 0031808446 scopus 로고    scopus 로고
    • Serum collagen crosslinks as markers of bone turn-over during GH replacement therapy in growth hormone deficient adults
    • DOI 10.1046/j.1365-2265.1998.00405.x
    • Rodríguez-Arnao J., James I., Jabbar A., Trainer P. J., Perrett D., Besser G. M., Ross R. J. M., Serum collagen crosslinks as markers of bone turn-over during GH replacement therapy in growth hormone deficient adults. Clinical Endocrinology 1998 48 4 455 462 2-s2.0-0031808446 10.1046/j.1365-2265. 1998.00405.x (Pubitemid 28258818)
    • (1998) Clinical Endocrinology , vol.48 , Issue.4 , pp. 455-462
    • Rodriguez-Arnao, J.1    James, I.2    Jabbar, A.3    Trainer, P.J.4    Perrett, D.5    Besser, G.M.6    Ross, R.J.M.7
  • 17
    • 0034453773 scopus 로고    scopus 로고
    • Withdrawal of long-term physiological growth hormone (GH) administration: Differential effects on bone density and body composition in men with adult-onset GH deficiency
    • DOI 10.1210/jc.85.3.970
    • Biller B. M. K., Sesmilo G., Baum H. B. A., Hayden D., Schoenfeld D., Klibanski A., Withdrawal of long-term physiological growth hormone (GH) administration: differential effects on bone density and body composition in men with adult-onset GH deficiency. Journal of Clinical Endocrinology and Metabolism 2000 85 3 970 976 2-s2.0-0034453773 10.1210/jc.85.3.970 (Pubitemid 32269335)
    • (2000) Journal of Clinical Endocrinology and Metabolism , vol.85 , Issue.3 , pp. 970-976
    • Biller, B.M.K.1    Sesmilo, G.2    Baum, H.B.A.3    Hayden, D.4    Schoenfeld, D.5    Klibanski, A.6
  • 18
    • 0034751043 scopus 로고    scopus 로고
    • Baseline characteristics and the effects of five years of GH replacement therapy in adults with GH deficiency of childhood or adulthood onset: A comparative, prospective study
    • DOI 10.1210/jc.86.10.4693
    • Koranyi J., Svensson J., Götherström G., Sunnerhagen K. S., Bengtsson B. Å., Johannsson G., Baseline characteristics and the effects of five years of GH replacement therapy in adults with GH deficiency of childhood or adulthood onset: a comparative, prospective study. Journal of Clinical Endocrinology and Metabolism 2001 86 10 4693 4699 2-s2.0-0034751043 10.1210/jc.86.10.4693 (Pubitemid 33026071)
    • (2001) Journal of Clinical Endocrinology and Metabolism , vol.86 , Issue.10 , pp. 4693-4699
    • Koranyi, J.1    Svensson, J.2    Gotherstrom, G.3    Sunnerhagen, K.S.4    Bengtsson, B.-A.5    Johannsson, G.6
  • 19
    • 0037292935 scopus 로고    scopus 로고
    • GH replacement therapy increases plasma osteoprotegerin levels in GH-deficient adults
    • DOI 10.1530/eje.0.1480185
    • Lanzi R., Losa M., Villa I., Gatti E., Sirtori M., Dal Fiume C., Rubinacci A., GH replacement therapy increases plasma osteoprotegerin levels in GH-deficient adults. European Journal of Endocrinology 2003 148 2 185 191 2-s2.0-0037292935 10.1530/eje.0.1480185 (Pubitemid 36312939)
    • (2003) European Journal of Endocrinology , vol.148 , Issue.2 , pp. 185-191
    • Lanzi, R.1    Losa, M.2    Villa, I.3    Gatti, E.4    Sirtori, M.5    Dal Fiume, C.6    Rubinacci, A.7
  • 20
    • 0344011427 scopus 로고    scopus 로고
    • Growth Hormone (GH) Dose-Response in Young Adults with Childhood-Onset GH Deficiency: A Two-Year, Multicenter, Multiple-Dose, Placebo-Controlled Study
    • DOI 10.1210/jc.2003-030204
    • Underwood L. E., Attie K. M., Baptista J., Growth hormone (GH) dose-response in young adults with childhood-onset GH deficiency: a two-year, multicenter, multiple-dose, Placebo-controlled study. Journal of Clinical Endocrinology and Metabolism 2003 88 11 5273 5280 2-s2.0-0344011427 10.1210/jc.2003-030204 (Pubitemid 37452727)
    • (2003) Journal of Clinical Endocrinology and Metabolism , vol.88 , Issue.11 , pp. 5273-5280
    • Underwood, L.E.1    Attie, K.M.2    Baptista, J.3
  • 22
    • 25444453727 scopus 로고    scopus 로고
    • Effect of long-term growth hormone treatment on bone mass and bone metabolism in growth hormone-deficient men
    • DOI 10.1359/JBMR.050613
    • Bravenboer N., Holzmann P. J., Ter Maaten J. C., Stuurman L. M., Roos J. C., Lips P., Effect of long-term growth hormone treatment on bone mass and bone metabolism in growth hormone-deficient men. Journal of Bone and Mineral Research 2005 20 10 1778 1784 2-s2.0-25444453727 10.1359/JBMR.050613 (Pubitemid 41361878)
    • (2005) Journal of Bone and Mineral Research , vol.20 , Issue.10 , pp. 1778-1784
    • Bravenboer, N.1    Holzmann, P.J.2    Ter Maaten, J.C.3    Stuurman, L.M.4    Roos, J.C.5    Lips, P.6
  • 23
    • 24144432081 scopus 로고    scopus 로고
    • Effects of 10 years of growth hormone (GH) replacement therapy in adult GH-deficient men
    • DOI 10.1111/j.1365-2265.2005.02343.x
    • Arwert L. I., Roos J. C., Lips P., Twisk J. W. R., Manoliu R. A., Drent M. L., Effects of 10 years of growth hormone (GH) replacement therapy in adult GH-deficient men. Clinical Endocrinology 2005 63 3 310 316 2-s2.0-24144432081 10.1111/j.1365-2265.2005.02343.x (Pubitemid 41233449)
    • (2005) Clinical Endocrinology , vol.63 , Issue.3 , pp. 310-316
    • Arwert, L.I.1    Roos, J.C.2    Lips, P.3    Twisk, J.W.R.4    Manoliu, R.A.5    Drent, M.L.6
  • 24
    • 13244275093 scopus 로고    scopus 로고
    • One year of GH replacement therapy with a fixed low-dose regimen improves body composition, bone mineral density and lipid profile of GH-deficient adults
    • DOI 10.1530/eje.1.01817
    • Boguszewski C. L., Meister L. H. F., Zaninelli D. C. T., Radominski R. B., One year of GH replacement therapy with a fixed low-dose regimen improves body composition, bone mineral density and lipid profile of GH-deficient adults. European Journal of Endocrinology 2005 152 1 67 75 2-s2.0-13244275093 10.1530/eje.1.01817 (Pubitemid 40192469)
    • (2005) European Journal of Endocrinology , vol.152 , Issue.1 , pp. 67-75
    • Boguszewski, C.L.1    Meister, L.H.F.2    Zaninelli, D.C.T.3    Radominski, R.B.4
  • 25
    • 33645744658 scopus 로고    scopus 로고
    • Effect of short-term therapy with recombinant human growth hormone (GH) on metabolic parameters and preclinical atherosclerotic markers in hypopituitary patients with growth hormone deficiency
    • 2-s2.0-33645744658 10.1055/s-2006-924970
    • Benedini S., Dalle Carbonare L., Albiger N., Scanarini M., Bilora F., Petrobelli F., Giannini S., Mantero F., Scaroni C., Effect of short-term therapy with recombinant human growth hormone (GH) on metabolic parameters and preclinical atherosclerotic markers in hypopituitary patients with growth hormone deficiency. Hormone and Metabolic Research 2006 38 1 16 21 2-s2.0-33645744658 10.1055/s-2006-924970
    • (2006) Hormone and Metabolic Research , vol.38 , Issue.1 , pp. 16-21
    • Benedini, S.1    Dalle Carbonare, L.2    Albiger, N.3    Scanarini, M.4    Bilora, F.5    Petrobelli, F.6    Giannini, S.7    Mantero, F.8    Scaroni, C.9
  • 27
    • 34147153476 scopus 로고    scopus 로고
    • Ten-year GH replacement increase bone mineral density in hypopituitary patients with adult onset GH deficiency
    • DOI 10.1530/eje.1.02317
    • Gotherstrom G., Bengtsson B. A., Bossæus I., Johansson G., Svensson J., Ten-year GH replacement increase bone mineral density in hypopituitary patients with adult onset GH deficiency. European Journal of Endocrinology 2007 156 1 55 64 2-s2.0-34147153476 10.1530/eje.1.02317 (Pubitemid 46561839)
    • (2007) European Journal of Endocrinology , vol.156 , Issue.1 , pp. 55-64
    • Gotherstrom, G.1    Bengtsson, B.-A.2    Bossaeus, I.3    Johansson, G.4    Svensson, J.5
  • 28
    • 42649103615 scopus 로고    scopus 로고
    • Bone density and turnover in young adult patients with growth hormone deficiency after 2-year growth hormone replacement according with gender
    • Rota F., Savanelli M. C., Tauchmanova L., Savastano S., Lombardi G., Colao A., Di Somma C., Bone density and turnover in young adult patients with growth hormone deficiency after 2-year growth hormone replacement according with gender. Journal of Endocrinological Investigation 2008 31 2 94 103 2-s2.0-42649103615 (Pubitemid 351596968)
    • (2008) Journal of Endocrinological Investigation , vol.31 , Issue.2 , pp. 94-103
    • Rota, F.1    Savanelli, M.C.2    Tauchmanova, L.3    Savastano, S.4    Lombardi, G.5    Colao, A.6    Di Somma, C.7
  • 29
    • 66149085630 scopus 로고    scopus 로고
    • Treatment for 24 months with recombinant human GH has a beneficial effect on bone mineral density in young adults with childhood-onset GH deficiency
    • 2-s2.0-66149085630 10.1530/EJE-08-0436
    • Conway G. S., Szarras-Czapnik M., Racz K., Keller A., Chanson P., Tauber M., Zacharin M., Treatment for 24 months with recombinant human GH has a beneficial effect on bone mineral density in young adults with childhood-onset GH deficiency. European Journal of Endocrinology 2009 160 6 899 907 2-s2.0-66149085630 10.1530/EJE-08-0436
    • (2009) European Journal of Endocrinology , vol.160 , Issue.6 , pp. 899-907
    • Conway, G.S.1    Szarras-Czapnik, M.2    Racz, K.3    Keller, A.4    Chanson, P.5    Tauber, M.6    Zacharin, M.7
  • 30
    • 84862085719 scopus 로고    scopus 로고
    • Fifteen years of GH replacement increases bone mineral density in hypopituitary patients with adult-onset GH deficiency
    • 10.1530/EJE-11-1072
    • Elbornsson M., Gotherstrom G., Bosaeus I., Bengtsson B. A., Johannsson G., Svensson J., Fifteen years of GH replacement increases bone mineral density in hypopituitary patients with adult-onset GH deficiency. European Journal of Endocrinology 2012 166 5 787 795 10.1530/EJE-11-1072
    • (2012) European Journal of Endocrinology , vol.166 , Issue.5 , pp. 787-795
    • Elbornsson, M.1    Gotherstrom, G.2    Bosaeus, I.3    Bengtsson, B.A.4    Johannsson, G.5    Svensson, J.6
  • 31
    • 0023635603 scopus 로고
    • Growth hormone receptor and serum binding protein: Purification, cloning and expression
    • DOI 10.1038/330537a0
    • Leung D. W., Spencer S. A., Cachianes G., Hammonds R. G., Collins C., Henzel W. J., Barnard R., Waters M. J., Wood W. I., Growth hormone receptor and serum binding protein: purification, cloning and expression. Nature 1987 330 6148 537 543 2-s2.0-0023635603 (Pubitemid 17164350)
    • (1987) Nature , vol.330 , Issue.6148 , pp. 537-543
    • Leung, D.W.1    Spencer, S.A.2    Cachianes, G.3    Hammonds, R.G.4    Collins, C.5    Henzel, W.J.6    Barnard, R.7    Waters, M.J.8    Wood, W.I.9
  • 32
    • 84862076724 scopus 로고    scopus 로고
    • GH activity and markers of inflammation: A crossover study in healthy volunteers treated with GH and a GH receptor antagonist
    • 10.1530/EJE-11-1009
    • Andreassen M., Frystyk J., Faber J., Kristensen L. O., GH activity and markers of inflammation: a crossover study in healthy volunteers treated with GH and a GH receptor antagonist. European Journal of Endocrinology 2012 166 5 811 819 10.1530/EJE-11-1009
    • (2012) European Journal of Endocrinology , vol.166 , Issue.5 , pp. 811-819
    • Andreassen, M.1    Frystyk, J.2    Faber, J.3    Kristensen, L.O.4
  • 33
    • 0023688545 scopus 로고
    • Expression of insulin-like growth factor i in transgenic mice with elevated levels of growth hormone is correlated with growth
    • 2-s2.0-0023688545
    • Mathews L. S., Hammer R. E., Brinster R. L., Palmiter R. D., Expression of insulin-like growth factor I in transgenic mice with elevated levels of growth hormone is correlated with growth. Endocrinology 1988 123 1 433 437 2-s2.0-0023688545
    • (1988) Endocrinology , vol.123 , Issue.1 , pp. 433-437
    • Mathews, L.S.1    Hammer, R.E.2    Brinster, R.L.3    Palmiter, R.D.4
  • 35
    • 84867492236 scopus 로고    scopus 로고
    • Effects on insulin sensitivity and body composition of combination therapy with GH and IGF1 in GH deficient adults with type 2 diabetes
    • 10.1530/EJE-12-0484
    • Barner C., Petersson M., Eden Engstrom B., Hoybye,: C., Effects on insulin sensitivity and body composition of combination therapy with GH and IGF1 in GH deficient adults with type 2 diabetes. European Journal of Endocrinology 2012 167 5 697 703 10.1530/EJE-12-0484
    • (2012) European Journal of Endocrinology , vol.167 , Issue.5 , pp. 697-703
    • Barner, C.1    Petersson, M.2    Eden Engstrom, B.3    Hoybye, C.4
  • 36
    • 0024437318 scopus 로고
    • Insulin-like growth factors; autocrine, paracrine or endocrine? New perspectives of the somatomedin hypothesis in the light of recent developments
    • Holly J. M. P., Wass J. A. H., Insulin-like growth factors; autocrine, paracrine or endocrine? New perspectives of the somatomedin hypothesis in the light of recent developments. Journal of Endocrinology 1989 122 3 611 618 2-s2.0-0024437318 (Pubitemid 19220615)
    • (1989) Journal of Endocrinology , vol.122 , Issue.3 , pp. 611-618
    • Holly, J.M.P.1    Wass, J.A.H.2
  • 37
    • 84859979292 scopus 로고    scopus 로고
    • Targeting the insulin growth factor receptor 1
    • 10.1016/j.hoc.2012.01.004
    • Arnaldez F. I., Helman L. J., Targeting the insulin growth factor receptor 1. Hematology/Oncology Clinics of North America 2012 26 3 527 542 10.1016/j.hoc.2012.01.004
    • (2012) Hematology/Oncology Clinics of North America , vol.26 , Issue.3 , pp. 527-542
    • Arnaldez, F.I.1    Helman, L.J.2
  • 39
    • 0027996086 scopus 로고
    • Growth hormone stimulates proliferation of normal human bone marrow stromal osteoblast precursor cells in vitro
    • Kassem M., Mosekilde L., Eriksen E. F., Growth hormone stimulates proliferation of normal human bone marrow stromal osteoblast precursor cells in vitro. Growth Regulation 1994 4 3 131 135 2-s2.0-0027996086 (Pubitemid 24315352)
    • (1994) Growth Regulation , vol.4 , Issue.3 , pp. 131-135
    • Kassem, M.1    Mosekilde, L.2    Eriksen, E.F.3
  • 40
    • 84926122920 scopus 로고    scopus 로고
    • Endocrine regulation of longitudinal bone growth
    • 10.1159/000328119
    • Wit J. M., Camacho-Hubner C., Endocrine regulation of longitudinal bone growth. Endocrine Development 2011 21 30 41 10.1159/000328119
    • (2011) Endocrine Development , vol.21 , pp. 30-41
    • Wit, J.M.1    Camacho-Hubner, C.2
  • 41
    • 0034084798 scopus 로고    scopus 로고
    • Dynamics of bone turnover in children with GH deficiency treated with GH until final height
    • Baroncelli G. I., Bertelloni S., Ceccarelli C., Cupelli D., Saggese G., Dynamics of bone turnover in children with GH deficiency treated with GH until final height. European Journal of Endocrinology 2000 142 6 549 556 2-s2.0-0034084798 (Pubitemid 30399483)
    • (2000) European Journal of Endocrinology , vol.142 , Issue.6 , pp. 549-556
    • Baroncelli, G.I.1    Bertelloni, S.2    Ceccarelli, C.3    Cupelli, D.4    Saggese, G.5
  • 42
    • 68349146822 scopus 로고    scopus 로고
    • Is increase in bone mineral content caused by increase in skeletal muscle mass/strength in adult patients with GH-treated GH deficiency? A systematic literature analysis
    • 2-s2.0-68349146822 10.1530/EJE-09-0160
    • Klefter O., Feldt-Rasmussen U., Is increase in bone mineral content caused by increase in skeletal muscle mass/strength in adult patients with GH-treated GH deficiency? A systematic literature analysis. European Journal of Endocrinology 2009 161 2 213 221 2-s2.0-68349146822 10.1530/EJE-09-0160
    • (2009) European Journal of Endocrinology , vol.161 , Issue.2 , pp. 213-221
    • Klefter, O.1    Feldt-Rasmussen, U.2
  • 43
    • 0034517413 scopus 로고    scopus 로고
    • Relative influence of physical activity, muscle mass and strength on bone density
    • DOI 10.1007/s001980070033
    • Proctor D. N., Melton L. J., Khosla S., Crowson C. S., O'Connor M. K., Riggs B. L., Relative influence of physical activity, muscle mass and strength on bone density. Osteoporosis International 2000 11 11 944 952 2-s2.0-0034517413 10.1007/s001980070033 (Pubitemid 32044075)
    • (2000) Osteoporosis International , vol.11 , Issue.11 , pp. 944-952
    • Proctor, D.N.1    Melton III, L.J.2    Khosla, S.3    Crowson, C.S.4    O'Connor, M.K.5    Riggs, B.L.6
  • 44
    • 0033777443 scopus 로고    scopus 로고
    • The Utah paradigm of skeletal physiology: An overview of its insights for bone, cartilage and collagenous tissue organs
    • 2-s2.0-0033777443 10.1007/s007740070001
    • Frost H. M., The Utah paradigm of skeletal physiology: an overview of its insights for bone, cartilage and collagenous tissue organs. Journal of Bone and Mineral Metabolism 2000 18 6 305 316 2-s2.0-0033777443 10.1007/s007740070001
    • (2000) Journal of Bone and Mineral Metabolism , vol.18 , Issue.6 , pp. 305-316
    • Frost, H.M.1
  • 45
    • 49549111375 scopus 로고    scopus 로고
    • Growth hormone, insulin-like growth factors, and the skeleton
    • 2-s2.0-49549111375 10.1210/er.2007-0036
    • Giustina A., Mazziotti G., Canalis E., Growth hormone, insulin-like growth factors, and the skeleton. Endocrine Reviews 2008 29 5 535 559 2-s2.0-49549111375 10.1210/er.2007-0036
    • (2008) Endocrine Reviews , vol.29 , Issue.5 , pp. 535-559
    • Giustina, A.1    Mazziotti, G.2    Canalis, E.3
  • 46
    • 84878437017 scopus 로고    scopus 로고
    • Analysis of short stature cases referred for genetic evaluation
    • 10.1007/s12098-012-0732-x
    • Kaur A., Phadke S. R., Analysis of short stature cases referred for genetic evaluation. The Indian Journal of Pediatrics 2012 79 12 1597 1600 10.1007/s12098-012-0732-x
    • (2012) The Indian Journal of Pediatrics , vol.79 , Issue.12 , pp. 1597-1600
    • Kaur, A.1    Phadke, S.R.2
  • 47
    • 0033058987 scopus 로고    scopus 로고
    • Dose titration and patient selection increases the efficacy of GH replacement in severely GH deficient adults
    • DOI 10.1046/j.1365-2265.1999.00722.x
    • Murray R. D., Skillicorn C. J., Howell S. J., Lissett C. A., Rahim A., Shalet S. M., Dose titration and patient selection increases the efficacy of GH replacement in severely GH deficient adults. Clinical Endocrinology 1999 50 6 749 757 2-s2.0-0033058987 10.1046/j.1365-2265.1999.00722.x (Pubitemid 29284509)
    • (1999) Clinical Endocrinology , vol.50 , Issue.6 , pp. 749-757
    • Murray, R.D.1    Skillicorn, C.J.2    Howell, S.J.3    Lissett, C.A.4    Rahim, A.5    Shalet, S.M.6
  • 49
    • 0035723728 scopus 로고    scopus 로고
    • The influence of gender on the short and long-term effects of growth hormone replacement on bone metabolism and bone mineral density in hypopituitary adults: A 5-year study
    • DOI 10.1046/j.1365-2265.2001.01246.x
    • Drake W. M., Rodríguez-Arnao J., Weaver J. U., James I. T., Coyte D., Spector T. D., Besser G. M., Monson J. P., The influence of gender on the short and long-term effects of growth hormone replacement on bone metabolism and bone mineral density in hypopituitary adults: a 5-year study. Clinical Endocrinology 2001 54 4 525 532 2-s2.0-0035723728 10.1046/j.1365-2265.2001. 01246.x (Pubitemid 34207705)
    • (2001) Clinical Endocrinology , vol.54 , Issue.4 , pp. 525-532
    • Drake, W.M.1    Rodriguez-Arnao, J.2    Weaver, J.U.3    James, I.T.4    Coyte, D.5    Spector, T.D.6    Besser, G.M.7    Monson, J.P.8
  • 50
    • 78951485139 scopus 로고    scopus 로고
    • The role of GH/IGF-I-mediated mechanisms in sex differences in cortical bone size in mice
    • 2-s2.0-78951485139 10.1007/s00223-010-9436-2
    • Olson L. E., Ohlsson C., Mohan S., The role of GH/IGF-I-mediated mechanisms in sex differences in cortical bone size in mice. Calcified Tissue International 2011 88 1 1 8 2-s2.0-78951485139 10.1007/s00223-010-9436-2
    • (2011) Calcified Tissue International , vol.88 , Issue.1 , pp. 1-8
    • Olson, L.E.1    Ohlsson, C.2    Mohan, S.3
  • 51
    • 4043091961 scopus 로고    scopus 로고
    • Comparison of continuation or cessation of growth hormone (GH) therapy on body composition and metabolic status in adolescents with severe GH deficiency at completion of linear growth
    • DOI 10.1210/jc.2003-031588
    • Carroll P. V., Drake W. M., Maher K. T., Metcalfe K., Shaw N. J., Dunger D. B., Cheetham T. D., Camacho-Hübner C., Savage M. O., Monson J. P., Comparison of continuation or cessation of growth hormone (GH) therapy on body composition and metabolic status in adolescents with severe GH deficiency at completion of linear growth. Journal of Clinical Endocrinology and Metabolism 2004 89 8 3890 3895 2-s2.0-4043091961 10.1210/jc.2003-031588 (Pubitemid 39071490)
    • (2004) Journal of Clinical Endocrinology and Metabolism , vol.89 , Issue.8 , pp. 3890-3895
    • Carroll, P.V.1    Drake, W.M.2    Maher, K.T.3    Metcalfe, K.4    Shaw, N.J.5    Dunger, D.B.6    Cheetham, T.D.7    Camacho-Hubner, C.8    Savage, M.O.9    Monson, J.P.10
  • 52
    • 33645923389 scopus 로고    scopus 로고
    • Aetiology, diagnosis, and management of hypopituitarism in adult life
    • 2-s2.0-33645923389 10.1136/pgmj.2005.039768
    • Prabhakar V. K. B., Shalet S. M., Aetiology, diagnosis, and management of hypopituitarism in adult life. Postgraduate Medical Journal 2006 82 966 259 266 2-s2.0-33645923389 10.1136/pgmj.2005.039768
    • (2006) Postgraduate Medical Journal , vol.82 , Issue.966 , pp. 259-266
    • Prabhakar, V.K.B.1    Shalet, S.M.2
  • 53
    • 33646511089 scopus 로고    scopus 로고
    • The influence of growth hormone status on physical impairments, functional limitations, and health-related quality of life in adults
    • 2-s2.0-33646511089 10.1210/er.2004-0022
    • Woodhouse L. J., Mukherjee A., Shalet S. M., Ezzat S., The influence of growth hormone status on physical impairments, functional limitations, and health-related quality of life in adults. Endocrine Reviews 2006 27 3 287 317 2-s2.0-33646511089 10.1210/er.2004-0022
    • (2006) Endocrine Reviews , vol.27 , Issue.3 , pp. 287-317
    • Woodhouse, L.J.1    Mukherjee, A.2    Shalet, S.M.3    Ezzat, S.4
  • 55
    • 27744481492 scopus 로고    scopus 로고
    • Differential effect sizes of growth hormone replacement on quality of life, well-being and health status in growth hormone deficient patients: A meta-analysis
    • DOI 10.1186/1477-7525-3-63
    • Deijen J. B., Arwert L. I., Witlox J., Drent M. L., Differential effect sizes of growth hormone replacement on quality of life, well-being and health status in growth hormone deficient patients: a meta-analysis. Health and Quality of Life Outcomes 2005 3 63 2-s2.0-27744481492 10.1186/1477-7525-3-63 (Pubitemid 41582043)
    • (2005) Health and Quality of Life Outcomes , vol.3 , pp. 63
    • Deijen, J.B.1    Arwert, L.I.2    Witlox, J.3    Drent, M.L.4
  • 56
    • 1942436958 scopus 로고    scopus 로고
    • Insulin-like growth factor (IGF)-I, IGF binding protein-3, and cancer risk: Systematic review and meta-regression analysis
    • DOI 10.1016/S0140-6736(04)16044-3, PII S0140673604160443
    • Renehan A. G., Zwahlen M., Minder C., O'Dwyer S. T., Shalet S. M., Egger M., Insulin-like growth factor (IGF)-I, IGF binding protein-3, and cancer risk: systematic review and meta-regression analysis. The Lancet 2004 363 9418 1346 1353 2-s2.0-1942436958 10.1016/S0140-6736(04)16044-3 (Pubitemid 38529873)
    • (2004) Lancet , vol.363 , Issue.9418 , pp. 1346-1353
    • Renehan, A.G.1    Zwahlen, M.2    Minder, C.3    O'Dwyer, S.T.4    Shalet, S.M.5    Egger, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.