메뉴 건너뛰기




Volumn 18, Issue 4, 2008, Pages 318-324

Comparative results of a 4-year study on cardiovascular parameters, lipid metabolism, body composition and bone mass between untreated and treated adult growth hormone deficient patients

Author keywords

Bone mineral content; Growth hormone deficiency; Growth hormone replacement; Untreated growth hormone deficient patients, cardiovascular risk factors

Indexed keywords

GLUCOSE; GROWTH HORMONE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYPOPHYSIS HORMONE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; SOMATOMEDIN C; TRIACYLGLYCEROL;

EID: 44349107604     PISSN: 10966374     EISSN: 15322238     Source Type: Journal    
DOI: 10.1016/j.ghir.2008.01.002     Document Type: Article
Times cited : (29)

References (30)
  • 2
    • 2142673373 scopus 로고    scopus 로고
    • Growth hormone deficiency in adulthood and the effects of growth hormone replacement: a review. Growth Hormone Research Society Scientific Committee
    • Carroll P.V., Christ E.R., Bengtsson B.-A., et al. Growth hormone deficiency in adulthood and the effects of growth hormone replacement: a review. Growth Hormone Research Society Scientific Committee. J. Clin. Endocrinol. Metab. 83 (1998) 382-395
    • (1998) J. Clin. Endocrinol. Metab. , vol.83 , pp. 382-395
    • Carroll, P.V.1    Christ, E.R.2    Bengtsson, B.-A.3
  • 3
    • 0024390712 scopus 로고
    • Beneficial effects of growth hormone treatment in GH-deficient adults
    • Jorgensen J.O.L., Pedersen S.A., Thuesen L., et al. Beneficial effects of growth hormone treatment in GH-deficient adults. Lancet 1 (1989) 1221-1225
    • (1989) Lancet , vol.1 , pp. 1221-1225
    • Jorgensen, J.O.L.1    Pedersen, S.A.2    Thuesen, L.3
  • 4
    • 0024854194 scopus 로고
    • The effects of treatment with recombinant human growth hormone on body composition and metabolism in adults with growth hormone deficiency
    • Salomon F., Cuneo R.C., Hesp H., and Sönksen P.H. The effects of treatment with recombinant human growth hormone on body composition and metabolism in adults with growth hormone deficiency. N. Engl. J. Med. 321 (1989) 1797-1803
    • (1989) N. Engl. J. Med. , vol.321 , pp. 1797-1803
    • Salomon, F.1    Cuneo, R.C.2    Hesp, H.3    Sönksen, P.H.4
  • 5
    • 0027514167 scopus 로고
    • Treatment of adults with growth hormone (GH) deficiency with recombinant human GH
    • Bengtsson B.-A., Edén S., Lünn I., et al. Treatment of adults with growth hormone (GH) deficiency with recombinant human GH. J. Clin. Endocrinol. Metab. 76 (1993) 309-317
    • (1993) J. Clin. Endocrinol. Metab. , vol.76 , pp. 309-317
    • Bengtsson, B.-A.1    Edén, S.2    Lünn, I.3
  • 6
    • 0031792510 scopus 로고    scopus 로고
    • Growth Hormone Research Society, Consensus guidelines for the diagnosis and treatments of adults with growth hormone deficiency: summary statement of the growth hormone research society workshop on adult growth hormone deficiency, J. Clin. Endocrinol. Metab. 83 (1998) 379-381.
    • Growth Hormone Research Society, Consensus guidelines for the diagnosis and treatments of adults with growth hormone deficiency: summary statement of the growth hormone research society workshop on adult growth hormone deficiency, J. Clin. Endocrinol. Metab. 83 (1998) 379-381.
  • 7
    • 33748752790 scopus 로고    scopus 로고
    • Medium and long-term outcome of growth hormone therapy in growth hormone deficient adults
    • Fideleff H.L., Boquete H., Giaccio A., and Sobrado P. Medium and long-term outcome of growth hormone therapy in growth hormone deficient adults. Medicina (B Aires) 66 (2006) 296-302
    • (2006) Medicina (B Aires) , vol.66 , pp. 296-302
    • Fideleff, H.L.1    Boquete, H.2    Giaccio, A.3    Sobrado, P.4
  • 8
    • 0033756446 scopus 로고    scopus 로고
    • Effects of 7 years of growth hormone replacement therapy in hypopituitary adults
    • Chrisoulidou A., Beshyah S., Rutherford O., et al. Effects of 7 years of growth hormone replacement therapy in hypopituitary adults. J. Clin. Endocrinol. Metab. 85 (2000) 3762-3769
    • (2000) J. Clin. Endocrinol. Metab. , vol.85 , pp. 3762-3769
    • Chrisoulidou, A.1    Beshyah, S.2    Rutherford, O.3
  • 9
    • 0242383399 scopus 로고    scopus 로고
    • Evaluation of diagnostic accuracy of insulin-like growth factor (IGF)-I and IGF-binding protein-3 in growth hormone-deficient children and adults using ROC plot analysis
    • Boquete H.R., Sobrado P.G., Fideleff H.L., et al. Evaluation of diagnostic accuracy of insulin-like growth factor (IGF)-I and IGF-binding protein-3 in growth hormone-deficient children and adults using ROC plot analysis. J. Clin. Endocrinol. Metab. 88 (2003) 4702-4708
    • (2003) J. Clin. Endocrinol. Metab. , vol.88 , pp. 4702-4708
    • Boquete, H.R.1    Sobrado, P.G.2    Fideleff, H.L.3
  • 10
    • 0033345441 scopus 로고    scopus 로고
    • The effect of 10 years of recombinant human growth hormone (GH) in adult GH-deficient patients
    • Gibney J., Wallace J.D., Spinks T., et al. The effect of 10 years of recombinant human growth hormone (GH) in adult GH-deficient patients. J. Clin. Endocrinol. Metab. 84 (1999) 2596-2602
    • (1999) J. Clin. Endocrinol. Metab. , vol.84 , pp. 2596-2602
    • Gibney, J.1    Wallace, J.D.2    Spinks, T.3
  • 11
    • 33646402056 scopus 로고    scopus 로고
    • Evaluation and treatment of adult growth hormone deficiency: an endocrine society clinical practice guideline
    • Molitch M., Clemmons D., Malozowski S., Merrian G., Shalet S., and Vance M. Evaluation and treatment of adult growth hormone deficiency: an endocrine society clinical practice guideline. J. Clin. Endocrinol. Metab. 91 (2006) 1621-1634
    • (2006) J. Clin. Endocrinol. Metab. , vol.91 , pp. 1621-1634
    • Molitch, M.1    Clemmons, D.2    Malozowski, S.3    Merrian, G.4    Shalet, S.5    Vance, M.6
  • 12
    • 33746377019 scopus 로고    scopus 로고
    • Does long-term GH replacement therapy in hypopituitary adults with GH deficiency normalise quality of life?
    • Koltowska-Häggström M., Mattsson A.F., Monson J.P., et al. Does long-term GH replacement therapy in hypopituitary adults with GH deficiency normalise quality of life?. Eur. J. Endocrinol. 155 (2006) 109-119
    • (2006) Eur. J. Endocrinol. , vol.155 , pp. 109-119
    • Koltowska-Häggström, M.1    Mattsson, A.F.2    Monson, J.P.3
  • 13
    • 33847282323 scopus 로고    scopus 로고
    • Growth hormone (GH) replacement therapy in GH deficient adults: predictors of one-year metabolic and clinical response
    • Svensson J., Finer N., Bouloux P., et al. Growth hormone (GH) replacement therapy in GH deficient adults: predictors of one-year metabolic and clinical response. Grow. Horm. IGF Res. 17 (2007) 67-76
    • (2007) Grow. Horm. IGF Res. , vol.17 , pp. 67-76
    • Svensson, J.1    Finer, N.2    Bouloux, P.3
  • 14
    • 0034682622 scopus 로고    scopus 로고
    • Effects of growth hormone administration on inflammatory and other cardiovascular risk markers in men with growth hormone deficiency. A randomized, controlled clinical trial
    • Sesmilo G., Biller B.M., Llevadot J., et al. Effects of growth hormone administration on inflammatory and other cardiovascular risk markers in men with growth hormone deficiency. A randomized, controlled clinical trial. Ann. Intern. Med. 133 (2000) 111-122
    • (2000) Ann. Intern. Med. , vol.133 , pp. 111-122
    • Sesmilo, G.1    Biller, B.M.2    Llevadot, J.3
  • 15
    • 2442526224 scopus 로고    scopus 로고
    • Impact of growth hormone (GH) treatment on cardiovascular risk factors in GH-deficient adults: a metaanalysis of blinded, randomized, Placebo-controlled trials
    • Maison P., Griffin S., Nicoue-Beglah M., Haddad N., Balkau B., and Chanson P. Impact of growth hormone (GH) treatment on cardiovascular risk factors in GH-deficient adults: a metaanalysis of blinded, randomized, Placebo-controlled trials. J. Clin. Endocrinol. Metab. 89 (2004) 2192-2199
    • (2004) J. Clin. Endocrinol. Metab. , vol.89 , pp. 2192-2199
    • Maison, P.1    Griffin, S.2    Nicoue-Beglah, M.3    Haddad, N.4    Balkau, B.5    Chanson, P.6
  • 16
    • 33845251657 scopus 로고    scopus 로고
    • Sustained effects of recombinant GH replacement after 7 years of treatment in adults with GH deficiency
    • Van der Klaauw A., Romijn J., Biermasz N., et al. Sustained effects of recombinant GH replacement after 7 years of treatment in adults with GH deficiency. Eur. J. Endocrinol. 155 (2006) 701-708
    • (2006) Eur. J. Endocrinol. , vol.155 , pp. 701-708
    • Van der Klaauw, A.1    Romijn, J.2    Biermasz, N.3
  • 17
    • 0030450507 scopus 로고    scopus 로고
    • Growth hormone versus placebo treatment for one year in growth hormone deficient adults: increase in exercise capacity and normalization of body composition
    • Jorgensen J.O., Vahl N., Hansen T.B., Thuesen L., Hagen C., and Christiansen J.S. Growth hormone versus placebo treatment for one year in growth hormone deficient adults: increase in exercise capacity and normalization of body composition. Clin. Endocrinol. 45 (1996) 681-688
    • (1996) Clin. Endocrinol. , vol.45 , pp. 681-688
    • Jorgensen, J.O.1    Vahl, N.2    Hansen, T.B.3    Thuesen, L.4    Hagen, C.5    Christiansen, J.S.6
  • 18
    • 0034853489 scopus 로고    scopus 로고
    • Gender differences in rhGH-induced changes in body composition in GH-deficient adults
    • Span J., Pieters G., Sweep F., Hermus A., and Smals A. Gender differences in rhGH-induced changes in body composition in GH-deficient adults. J. Clin. Endocrinol. Metab. 86 (2001) 4161-4165
    • (2001) J. Clin. Endocrinol. Metab. , vol.86 , pp. 4161-4165
    • Span, J.1    Pieters, G.2    Sweep, F.3    Hermus, A.4    Smals, A.5
  • 19
    • 33646511089 scopus 로고    scopus 로고
    • The influence of growth hormone status on physical impairments, functional limitations, and health-related quality of life in adults
    • Woodhouse L.J., Mukherjee A., Shalet S.M., and Ezzat S. The influence of growth hormone status on physical impairments, functional limitations, and health-related quality of life in adults. Endocrinol. Rev. 27 (2006) 287-317
    • (2006) Endocrinol. Rev. , vol.27 , pp. 287-317
    • Woodhouse, L.J.1    Mukherjee, A.2    Shalet, S.M.3    Ezzat, S.4
  • 20
    • 33746370734 scopus 로고    scopus 로고
    • Determinants of cardiovascular risk in 2589 hypopituitary GH-deficient adults - a KIMS database analysis
    • Abs R., Feldt-Rasmussen U., Mattsson A.F., et al. Determinants of cardiovascular risk in 2589 hypopituitary GH-deficient adults - a KIMS database analysis. Eur. J. Endocrinol. 155 (2006) 79-90
    • (2006) Eur. J. Endocrinol. , vol.155 , pp. 79-90
    • Abs, R.1    Feldt-Rasmussen, U.2    Mattsson, A.F.3
  • 21
    • 0034749231 scopus 로고    scopus 로고
    • A prospective study of 5 years of GH replacement therapy in GH-deficient adults: sustained effects on body composition, bone mass, and metabolic indices
    • Gotherstrom G., Svensson J., Koranyi J., et al. A prospective study of 5 years of GH replacement therapy in GH-deficient adults: sustained effects on body composition, bone mass, and metabolic indices. J. Clin. Endocrinol. Metab. 86 (2001) 4657-4665
    • (2001) J. Clin. Endocrinol. Metab. , vol.86 , pp. 4657-4665
    • Gotherstrom, G.1    Svensson, J.2    Koranyi, J.3
  • 22
    • 6344220064 scopus 로고    scopus 로고
    • Long-term effects of 7-year growth hormone substitution on bone metabolism, bone density, and bone quality in growth hormone-deficient adults
    • Wilhelm B., and Kann P.H. Long-term effects of 7-year growth hormone substitution on bone metabolism, bone density, and bone quality in growth hormone-deficient adults. Med. Klin. (Munich) 99 (2004) 569-577
    • (2004) Med. Klin. (Munich) , vol.99 , pp. 569-577
    • Wilhelm, B.1    Kann, P.H.2
  • 23
    • 13244275093 scopus 로고    scopus 로고
    • One year of GH replacement therapy with a fixed low-dose regimen improves body composition, bone mineral density and lipid profile of GH-deficient adults
    • Boguszewski C., Meister L., Zaninelli D., and Radominski R. One year of GH replacement therapy with a fixed low-dose regimen improves body composition, bone mineral density and lipid profile of GH-deficient adults. Eur. J. Endocrinol. 152 (2005) 67-75
    • (2005) Eur. J. Endocrinol. , vol.152 , pp. 67-75
    • Boguszewski, C.1    Meister, L.2    Zaninelli, D.3    Radominski, R.4
  • 24
    • 6344276844 scopus 로고    scopus 로고
    • Bone status and fracture prevalence in Russian adults with childhood-onset growth hormone deficiency
    • Bouillon R., Koledova E., Bezlepkina O., et al. Bone status and fracture prevalence in Russian adults with childhood-onset growth hormone deficiency. J. Clin. Endocrinol. Metab. 89 (2004) 4993-4998
    • (2004) J. Clin. Endocrinol. Metab. , vol.89 , pp. 4993-4998
    • Bouillon, R.1    Koledova, E.2    Bezlepkina, O.3
  • 25
    • 0028195039 scopus 로고
    • Gender differences in bone density, skeletal geometry, and fracture biomechanics
    • Genant H., Gluer C., and Lotz J. Gender differences in bone density, skeletal geometry, and fracture biomechanics. Radiology 190 (1994) 636-640
    • (1994) Radiology , vol.190 , pp. 636-640
    • Genant, H.1    Gluer, C.2    Lotz, J.3
  • 26
    • 0032699216 scopus 로고    scopus 로고
    • The differing tempo of growth in bone size, mass, and density in girls in region-specific
    • Bass S., Delmas P., Pearce G., Hendrich E., Tabensky A., and Seeman E. The differing tempo of growth in bone size, mass, and density in girls in region-specific. J. Clin. Invest. 104 (1999) 795-804
    • (1999) J. Clin. Invest. , vol.104 , pp. 795-804
    • Bass, S.1    Delmas, P.2    Pearce, G.3    Hendrich, E.4    Tabensky, A.5    Seeman, E.6
  • 27
    • 0034685191 scopus 로고    scopus 로고
    • Incidence of diabetes mellitus and impaired glucose tolerance in children and adolescents receiving growth-hormone treatment
    • Cutfield W., Wilton P., Bennmarker H., et al. Incidence of diabetes mellitus and impaired glucose tolerance in children and adolescents receiving growth-hormone treatment. Lancet 355 (2000) 610-613
    • (2000) Lancet , vol.355 , pp. 610-613
    • Cutfield, W.1    Wilton, P.2    Bennmarker, H.3
  • 28
    • 26644463217 scopus 로고    scopus 로고
    • Improvement in insulin sensitivity without concomitant changes in body composition and cardiovascular risk markers following fixed administration of a very low growth hormone (GH) dose in adults with severe GH deficiency
    • Yuen K.C., Frystyk J., White D.K., et al. Improvement in insulin sensitivity without concomitant changes in body composition and cardiovascular risk markers following fixed administration of a very low growth hormone (GH) dose in adults with severe GH deficiency. Clin. Endocrinol. (Oxf) 63 (2005) 428-436
    • (2005) Clin. Endocrinol. (Oxf) , vol.63 , pp. 428-436
    • Yuen, K.C.1    Frystyk, J.2    White, D.K.3
  • 29
    • 23744434990 scopus 로고    scopus 로고
    • Dysglycemia, not just diabetes, is a continuous risk factor for cardiovascular disease
    • Gerstein H.C. Dysglycemia, not just diabetes, is a continuous risk factor for cardiovascular disease. Evidence-Based Cardiovas. Med. 1 (1997) 87-88
    • (1997) Evidence-Based Cardiovas. Med. , vol.1 , pp. 87-88
    • Gerstein, H.C.1
  • 30
    • 0032902850 scopus 로고    scopus 로고
    • The relationship between glucose and incident cardiovascular events. A metaregression analysis of published data from 20 studies of 95.783 individuals followed for 12.4 years
    • Coutinho M., Gerstein H.C., Wang Y., and Yusuf S. The relationship between glucose and incident cardiovascular events. A metaregression analysis of published data from 20 studies of 95.783 individuals followed for 12.4 years. Diabet. Care 22 (1999) 233-240
    • (1999) Diabet. Care , vol.22 , pp. 233-240
    • Coutinho, M.1    Gerstein, H.C.2    Wang, Y.3    Yusuf, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.