MSM Enhances GH Signaling via the Jak2/STAT5b Pathway in Osteoblast-Like Cells and Osteoblast Differentiation through the Activation of STAT5b in MSCs

PLoS ONE

Volumn 7, Issue 10, 2012, Pages

  Joung, Youn Hee ^a   Lim, Eun Joung ^a   Darvin, Pramod ^a   Chung, So Chung ^a   Jang, Ju Woong ^b   Do Park, Kyung ^c   Lee, Hak Kyo ^c   Kim, Heui Soo ^d   Park, Taekyu ^e   Yang, Young Mok ^a  

^a Konkuk University School of Medicine   (South Korea)

^b Korea Bone Bank Co Ltd   (South Korea)

^c Hankyong National University   (South Korea)

^d Pusan National University   (South Korea)

^e Konkuk University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; DIMETHYL SULFONE; GROWTH HORMONE; GROWTH HORMONE RECEPTOR; JANUS KINASE 2; MESSENGER RNA; SOMATOMEDIN C RECEPTOR; STAT5B PROTEIN;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL DIFFERENTIATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE EXPRESSION; MARKER GENE; MOUSE; NONHUMAN; OSTEOBLAST; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANALYSIS OF VARIANCE; ANIMALS; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELL LINE, TUMOR; DIMETHYL SULFOXIDE; DNA PRIMERS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GROWTH HORMONE; IMMUNOPRECIPITATION; JANUS KINASE 2; LUCIFERASES; MESENCHYMAL STROMAL CELLS; OSTEOBLASTS; OSTEOGENESIS; RATS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; STAT5 TRANSCRIPTION FACTOR; SULFONES; TETRAZOLIUM SALTS; THIAZOLES;

EID: 84867429651     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0047477     Document Type: Article

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