Effects of chronic sazetidine-A, a selective α4β2 neuronal nicotinic acetylcholine receptors desensitizing agent on pharmacologically- induced impaired attention in rats

Psychopharmacology

Volumn 226, Issue 1, 2013, Pages 35-43

  Rezvani, Amir H ^a   Cauley, Marty ^a   Xiao, Yingxian ^b   Kellar, Kenneth J ^b   Levin, Edward D ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Animal model; Cognition; Nicotinic receptors; Scopolamine

Indexed keywords

DESENSITIZING AGENT; DIZOCILPINE; NICOTINIC RECEPTOR ALPHA4BETA2; PLACEBO; SAZETIDINE A; SCOPOLAMINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATTENTION DISTURBANCE; BINDING AFFINITY; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFICACY; DRUG PROTEIN BINDING; DRUG TREATMENT FAILURE; EXPERIMENTAL RAT; FEMALE; NONHUMAN; PRIORITY JOURNAL; RAT; TASK PERFORMANCE;

ANIMALS; ATTENTION; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; AZETIDINES; CONDITIONING, OPERANT; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; INFUSIONS, SUBCUTANEOUS; LIGANDS; MUSCARINIC ANTAGONISTS; PROTEIN BINDING; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; REACTION TIME; RECEPTORS, NICOTINIC; SCOPOLAMINE HYDROBROMIDE;

EID: 84877119807     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-012-2895-6     Document Type: Article

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