Structure and activation of muscarinic acetylcholine receptors

Biochemical Society Transactions

Volumn 31, Issue 1, 2003, Pages 29-34

  Hulme, E C ^a   Lu, Z L ^b   Saldanha, J W ^a   Bee, M S ^b  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

G protein coupled receptor; G protein; Rhodopsin

Indexed keywords

ACETYLCHOLINE; AMINO ACID; CHOLINERGIC RECEPTOR; DOCKING PROTEIN; MEMBRANE PROTEIN; MEMBRANE PROTEIN TM3; MEMBRANE PROTEIN TM4; MEMBRANE PROTEIN TM6; MEMBRANE PROTEIN TM7; METHYLSCOPOLAMINE; MUSCARINIC AGENT; MUSCARINIC M1 RECEPTOR; MUSCARINIC RECEPTOR; MUSCARINIC RECEPTOR BLOCKING AGENT; RHODOPSIN; UNCLASSIFIED DRUG;

BINDING SITE; CATTLE; CONFERENCE PAPER; ENERGY; GENE DISRUPTION; HUMAN; HYDROGEN BOND; LIGAND BINDING; MEMBRANE BINDING; MEMBRANE STABILIZATION; MEMBRANE STRUCTURE; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN STABILITY; PROTEIN STRUCTURE; RECEPTOR BINDING; RECEPTOR UPREGULATION; REGULATORY MECHANISM; RESIDUE ANALYSIS; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; X RAY ANALYSIS;

BOS TAURUS; BOVINAE;

EID: 0037329292     PISSN: 03005127     EISSN: None     Source Type: Journal    
DOI: 10.1042/bst0310029     Document Type: Conference Paper

References (41)

1. Hulme, E.C., Birdsall, N.J. and Buckley, N.J. (1990) Annu. Rev. Pharmacol. Toxicol. 30, 633-673
2. Baldwin, J.M., Schertler, G.F.X. and Unger, V.M. (1997) J. Mol. Biol. 272, 144-164
3. Unger, V.M., Hargrave, P.A., Baldwin, J.M. a.nd Schertler, G.F. (1997) Nature (London) 389, 203-206
4. Palczewski, K., Kumasaka, T., Hori, T., Behnke, C.A., Motoshima, H., Fox, B.A., Le Trong, I., Teller, D.C., Okada, T., Stenkamp, R.E. et al. (2000) Science 289, 739-745
5. Teller, D.C., Okada, T., Behnke, C.A., Palczewski, K. and Stenkamp, R.E. (2001) Biochemistry 40, 7761-7772
6. Gether, U. (2001) Endocrine Rev. 21, 90-113
7. Nathanson, N.M. (2000). Proc. Natl. Acad. Sci. U.S.A. 97, 6245-6247
8. Elling, C.E., Raffetseder, U., Nielsen, S.M. and Schwartz, T.W. (2000). Biochemistry 39, 667-675
9. Lu, Z.-L. and Hulme, E.C. (2000) J. Biol. Chem. 275, 5682-5686
10. Allman, K., Page, K.M., Curtis, C.A.M. and Hulme, E.C. (2000). Mol. Pharmacol. 58, 175-184
11. Samama, P., Cotecchia, S., Costa, T. and Lefkowitz, R.J. (1993) J. Biol. Chem. 268, 4625-4636
12. Lu, Z.-L., Saldanha, J. and Hulme, E.C. (2001) J. Biol. Chem. 276, 34098-34104
13. Lu, Z.L., Saldanha, J.W. and Hulme, E.C. (2002) Trends Pharmacol. Sci. 23, 140-146
14. Ballesteros, J.A. and Weinstein, H. (1995) Methods Neurosci. 25, 366-428
15. Lu, Z.-L., Curtis, C.AM., Jones, P.G., Pavia, J. and Hulme, E.C. (1997) Mol. Pharmacol. 51, 234-241
16. Hulme, E.C. and Lu, Z.-L. (1998). J. Physiol. Paris 92, 269-274
17. Jones, P.G., Curtis, C.A. and Hulme, E.C. (1995). Eur. J. Pharmacol. 288, 251-257
18. Page, K.M., Curtis, C.AM., Jones, P.G. and Hulme, E.C. (1995) Eur. J. Pharmacol. 289, 429-437
19. Ward, S.D.C., Curtis, C.AM. and Hulme, E.C. (1999). Mol. Pharmacol. 56, 1031-1041
20. Lu, Z.-L. and Hulme, E.C. (1999). J. Biol. Chem. 274, 7309-7315
21. Scheer, A., Fanelli, F., Costa, T., De Benedetti, P.G. and Cotecchia, S. (1997) Proc. Natl. Acad. Sci. U.S.A. 94, 808-813
22. Ballesteros, J.A., Jensen, A.D., Liapakis, G., Rasmussen, S.G.F., Shi, L., Gether, U. and Javitch, J.A. (2001) J. Biol. Chem. 276, 29171-29177
23. Alewjinse, A.E., Timmerman, H., Jacobs, H., Jacobs, E.H., Smit, M.J., Roovers, E., Cotecchia, S. and Leurs, R. (2000) Mol. Pharmacol. 57, 890-898
24. Shapiro, D.A., Kristiansen, K., Weiner, D.M., Kroeze, W.K. and Roth, B.L. (2002) J. Biol. Chem. 277, 11441-11449
25. Hibert, M., Trumpp-Kallmeyer, S., Bruinvels, A. and Hoflack, J. (1991) Mol. Pharmacol. 40, 8-15
26. Brejc, K., Van Dijk, W.J., Klaassen, R.V., Schuurmans, M., Van der Oost, J., Smit, A.B. and Sixma, T.K. (2001) Nature (London) 411, 269-276
27. Axelsen, P.H., Harel, M., Silman, I. and Sussman, J.L. (1994) Protein Sci. 3, 188-197
28. Ma, J.C. and Dougherty, D.A. (1997). Chem. Rev. 97, 1303-1324
29. Furukawa, H., Hamada, T., Hayashi, M.K., Haga, T., Muto, Y., Hirota, H., Yokoyama, S., Nagasawa, K. and Ishiguro, M. (2002) Mol. Pharmacol. 62, 778-787
30. Jakubik, J., El-Fakahany, E.E. and Tucek, S. (2000) J. Biol. Chem. 275, 18836-18844
31. Heitz, F., Holzwarth, J.A., Gies, J.-P., Pruss, R.M., Trumpp-Kallmeyer, S., Hibert, M. and Guenet, C. (1999) Eur. J. Pharmacol. 380, 183-105
32. Spalding, T.A., Burstein, E.S., Henderson, S.C., Ducote, K.R. and Brann, M.R. (1998) J. Biol. Chem. 273, 21563-21568
33. Chen, S., Lin, F., Xu, M. and Graham, R.M. (2002) Biochemistry 41, 588-596
34. Meng, E.C. and Bourne, H.R. (2001) Trends Pharmacol. Sci. 22, 587-593
35. Okada, T., Fujiyoshi, Y., Silow, M., Navarro, J., Landau, E.M. and Shichida, Y. (2002). Proc. Natl. Acad, Sci. U.S.A. 99, 5982-5987
36. Högger, P., Shockley, M.S., Lameh, J. and Sadee, W. (1995) J. Biol. Chem. 270, 7405-7410
37. Barlow, R.B. (1964) Introduction to Chemical Pharmacology, 2nd edn, Methuen, London
38. Schulman, J.M., Sabio, M.L. and Disch, R.L. (1983) J. Med. Chem. 26, 817-823
39. Ford, D.J., Essex, A., Spalding, T.A., Burstein, E.S. and Ellis, J. (2002) J. Pharmacol. Exp. Ther. 300, 810-817
40. Ward, S.D.C., Hamdan, F.F., Bloodworth, L.M. and Wess, J. (2002) J. Biol. Chem. 277, 2247-2257
41. Hulme, E.C. and Curtis, C.A.M. (1998) Biochem. Soc. Trans. 26, S361