메뉴 건너뛰기




Volumn 319, Issue 9, 2013, Pages 1264-1270

Transforming growth factor Β family members in regulation of vascular function: In the light of vascular conditional knockouts

Author keywords

Angiogenesis; Conditional; Endothelial; TGF ; Vascular stability

Indexed keywords

ENDOGLIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 3;

EID: 84877110299     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2013.02.015     Document Type: Review
Times cited : (51)

References (58)
  • 1
    • 80052015813 scopus 로고    scopus 로고
    • Molecular control of endothelial cell behaviour during blood vessel morphogenesis
    • Herbert S.P., Stainier D.Y. Molecular control of endothelial cell behaviour during blood vessel morphogenesis. Nat. Rev. Mol. Cell Biol. 2011, 12:551-564.
    • (2011) Nat. Rev. Mol. Cell Biol. , vol.12 , pp. 551-564
    • Herbert, S.P.1    Stainier, D.Y.2
  • 2
    • 35448991324 scopus 로고    scopus 로고
    • Extracellular control of TGFbeta signaling in vascular development and disease
    • ten Dijke P., Arthur H.M. Extracellular control of TGFbeta signaling in vascular development and disease. Nat. Rev. Mol. Cell Biol. 2007, 8:857-869.
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 857-869
    • ten Dijke, P.1    Arthur, H.M.2
  • 3
    • 0026646785 scopus 로고
    • Endoglin is a component of the transforming growth factor-beta receptor system in human endothelial cells
    • Cheifetz S., Bellón T., Calés C., Vera S., Bernabeu C., Massagué J., Letarte M. Endoglin is a component of the transforming growth factor-beta receptor system in human endothelial cells. J. Biol. Chem. 1992, 267:19027-19030.
    • (1992) J. Biol. Chem. , vol.267 , pp. 19027-19030
    • Cheifetz, S.1    Bellón, T.2    Calés, C.3    Vera, S.4    Bernabeu, C.5    Massagué, J.6    Letarte, M.7
  • 5
    • 70450187617 scopus 로고    scopus 로고
    • The regulation of TGFbeta signal transduction
    • Moustakas A., Heldin C.-H. The regulation of TGFbeta signal transduction. Development 2009, 136:3699-3714.
    • (2009) Development , vol.136 , pp. 3699-3714
    • Moustakas, A.1    Heldin, C.-H.2
  • 6
    • 24944497786 scopus 로고    scopus 로고
    • Non-Smad TGF-beta signals
    • Moustakas A., Heldin C.-H. Non-Smad TGF-beta signals. J. Cell Sci. 2005, 118:3573-3584.
    • (2005) J. Cell Sci. , vol.118 , pp. 3573-3584
    • Moustakas, A.1    Heldin, C.-H.2
  • 8
    • 0037007226 scopus 로고    scopus 로고
    • Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors
    • Goumans M.-J., Valdimarsdottir G., Itoh S., Rosendahl A., Sideras P., ten Dijke P. Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors. EMBO J. 2002, 21:1743-1753.
    • (2002) EMBO J. , vol.21 , pp. 1743-1753
    • Goumans, M.-J.1    Valdimarsdottir, G.2    Itoh, S.3    Rosendahl, A.4    Sideras, P.5    ten Dijke, P.6
  • 12
    • 0037114702 scopus 로고    scopus 로고
    • Activin receptor-like kinase 1 is implicated in the maturation phase of angiogenesis
    • Lamouille S., Mallet C., Feige J.-J., Bailly S. Activin receptor-like kinase 1 is implicated in the maturation phase of angiogenesis. Blood 2002, 100:4495-4501.
    • (2002) Blood , vol.100 , pp. 4495-4501
    • Lamouille, S.1    Mallet, C.2    Feige, J.-J.3    Bailly, S.4
  • 13
    • 33847369980 scopus 로고    scopus 로고
    • Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells
    • David L., Mallet C., Mazerbourg S., Feige J.-J., Bailly S. Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells. Blood 2007, 109:1953-1961.
    • (2007) Blood , vol.109 , pp. 1953-1961
    • David, L.1    Mallet, C.2    Mazerbourg, S.3    Feige, J.-J.4    Bailly, S.5
  • 14
    • 33750565365 scopus 로고    scopus 로고
    • TGFbeta1 induces vasculogenesis and inhibits angiogenic sprouting in an embryonic stem cell differentiation model: respective contribution of ALK1 and ALK5
    • Mallet C., Vittet D., Feige J.-J., Bailly S. TGFbeta1 induces vasculogenesis and inhibits angiogenic sprouting in an embryonic stem cell differentiation model: respective contribution of ALK1 and ALK5. Stem Cells 2006, 24:2420-2427.
    • (2006) Stem Cells , vol.24 , pp. 2420-2427
    • Mallet, C.1    Vittet, D.2    Feige, J.-J.3    Bailly, S.4
  • 16
    • 21644452716 scopus 로고    scopus 로고
    • Interaction and functional interplay between endoglin and ALK-1, two components of the endothelial transforming growth factor-beta receptor complex
    • Blanco F.J., Santibanez J.F., Guerrero-Esteo M., Langa C., Vary C.P.H., Bernabeu C. Interaction and functional interplay between endoglin and ALK-1, two components of the endothelial transforming growth factor-beta receptor complex. J. Cell Physiol. 2005, 204:574-584.
    • (2005) J. Cell Physiol. , vol.204 , pp. 574-584
    • Blanco, F.J.1    Santibanez, J.F.2    Guerrero-Esteo, M.3    Langa, C.4    Vary, C.P.H.5    Bernabeu, C.6
  • 18
    • 79961230399 scopus 로고    scopus 로고
    • Pericytes: developmental, physiological, and pathological perspectives, problems, and promises
    • Armulik A., Genové G., Betsholtz C. Pericytes: developmental, physiological, and pathological perspectives, problems, and promises. Dev. Cell 2011, 21:193-215.
    • (2011) Dev. Cell , vol.21 , pp. 193-215
    • Armulik, A.1    Genové, G.2    Betsholtz, C.3
  • 19
    • 33746829275 scopus 로고    scopus 로고
    • Transforming growth factor-betas and vascular disorders
    • Bobik A. Transforming growth factor-betas and vascular disorders. Arterioscler. Thromb. Vasc. Biol. 2006, 26:1712-1720.
    • (2006) Arterioscler. Thromb. Vasc. Biol. , vol.26 , pp. 1712-1720
    • Bobik, A.1
  • 20
    • 0029048550 scopus 로고
    • Regulation of differentiation of vascular smooth muscle cells
    • Owens G.K. Regulation of differentiation of vascular smooth muscle cells. Physiol. Rev. 1995, 75:487-517.
    • (1995) Physiol. Rev. , vol.75 , pp. 487-517
    • Owens, G.K.1
  • 21
    • 8144221439 scopus 로고    scopus 로고
    • Endothelial-mesenchymal interactions in vitro reveal molecular mechanisms of smooth muscle/pericyte differentiation
    • Ding R., Darland D.C., Parmacek M.S., D'Amore P.A. Endothelial-mesenchymal interactions in vitro reveal molecular mechanisms of smooth muscle/pericyte differentiation. Stem Cells Dev. 2004, 13:509-520.
    • (2004) Stem Cells Dev. , vol.13 , pp. 509-520
    • Ding, R.1    Darland, D.C.2    Parmacek, M.S.3    D'Amore, P.A.4
  • 22
    • 0029074681 scopus 로고
    • Defective haematopoiesis and vasculogenesis in transforming growth factor-beta 1 knock out mice
    • Dickson M.C., Martin J.S., Cousins F.M., Kulkarni A.B., Karlsson S., Akhurst R.J. Defective haematopoiesis and vasculogenesis in transforming growth factor-beta 1 knock out mice. Development 1995, 121:1845-1854.
    • (1995) Development , vol.121 , pp. 1845-1854
    • Dickson, M.C.1    Martin, J.S.2    Cousins, F.M.3    Kulkarni, A.B.4    Karlsson, S.5    Akhurst, R.J.6
  • 26
    • 33749379585 scopus 로고    scopus 로고
    • Bone morphogenetic protein receptor 1A signaling is dispensable for hematopoietic development but essential for vessel and atrioventricular endocardial cushion formation
    • Park C., Lavine K., Mishina Y., Deng C.-X., Ornitz D.M., Choi K. Bone morphogenetic protein receptor 1A signaling is dispensable for hematopoietic development but essential for vessel and atrioventricular endocardial cushion formation. Development 2006, 133:3473-3484.
    • (2006) Development , vol.133 , pp. 3473-3484
    • Park, C.1    Lavine, K.2    Mishina, Y.3    Deng, C.-X.4    Ornitz, D.M.5    Choi, K.6
  • 27
    • 38549145590 scopus 로고    scopus 로고
    • Functional characterization of bone morphogenetic protein binding sites and Smad1/5 activation in human vascular cells
    • Upton P.D., Long L., Trembath R.C., Morrell N.W. Functional characterization of bone morphogenetic protein binding sites and Smad1/5 activation in human vascular cells. Mol. Pharmacol. 2008, 73:539-552.
    • (2008) Mol. Pharmacol. , vol.73 , pp. 539-552
    • Upton, P.D.1    Long, L.2    Trembath, R.C.3    Morrell, N.W.4
  • 28
    • 33845878509 scopus 로고    scopus 로고
    • Tgfbeta signaling is required for atrioventricular cushion mesenchyme remodeling during in vivo cardiac development
    • Jiao K., Langworthy M., Batts L., Brown C.B., Moses H.L., Baldwin H.S. Tgfbeta signaling is required for atrioventricular cushion mesenchyme remodeling during in vivo cardiac development. Development 2006, 133:4585-4593.
    • (2006) Development , vol.133 , pp. 4585-4593
    • Jiao, K.1    Langworthy, M.2    Batts, L.3    Brown, C.B.4    Moses, H.L.5    Baldwin, H.S.6
  • 29
    • 12344255297 scopus 로고    scopus 로고
    • Defective paracrine signaling by TGFbeta in yolk sac vasculature of endoglin mutant mice: a paradigm for hereditary haemorrhagic telangiectasia
    • Carvalho R.L.C., Jonker L., Goumans M.-J., Larsson J., Bouwman P., Karlsson S., Dijke P.T., Arthur H.M., Mummery C.L. Defective paracrine signaling by TGFbeta in yolk sac vasculature of endoglin mutant mice: a paradigm for hereditary haemorrhagic telangiectasia. Development 2004, 131:6237-6247.
    • (2004) Development , vol.131 , pp. 6237-6247
    • Carvalho, R.L.C.1    Jonker, L.2    Goumans, M.-J.3    Larsson, J.4    Bouwman, P.5    Karlsson, S.6    Dijke, P.T.7    Arthur, H.M.8    Mummery, C.L.9
  • 32
    • 30944436695 scopus 로고    scopus 로고
    • Nonoverlapping expression patterns of ALK1 and ALK5 reveal distinct roles of each receptor in vascular development
    • Seki T., Hong K.-H., Oh S.P. Nonoverlapping expression patterns of ALK1 and ALK5 reveal distinct roles of each receptor in vascular development. Lab. Invest.: A J. Tech. Methods Pathol. 2006, 86:116-129.
    • (2006) Lab. Invest.: A J. Tech. Methods Pathol. , vol.86 , pp. 116-129
    • Seki, T.1    Hong, K.-H.2    Oh, S.P.3
  • 34
    • 50349096148 scopus 로고    scopus 로고
    • Genetic ablation of the BMPR2 gene in pulmonary endothelium is sufficient to predispose to pulmonary arterial hypertension
    • Hong K.-H., Lee Y.J., Lee E., Park S.O., Han C., Beppu H., Li E., Raizada M.K., Bloch K.D., Oh S.P. Genetic ablation of the BMPR2 gene in pulmonary endothelium is sufficient to predispose to pulmonary arterial hypertension. Circulation 2008, 118:722-730.
    • (2008) Circulation , vol.118 , pp. 722-730
    • Hong, K.-H.1    Lee, Y.J.2    Lee, E.3    Park, S.O.4    Han, C.5    Beppu, H.6    Li, E.7    Raizada, M.K.8    Bloch, K.D.9    Oh, S.P.10
  • 38
    • 84862743482 scopus 로고    scopus 로고
    • Endothelial expression of TGFΒ type II receptor is required to maintain vascular integrity during postnatal development of the central nervous system
    • Allinson K.R., Lee H.S., Fruttiger M., McCarty J., Arthur H.M. Endothelial expression of TGFΒ type II receptor is required to maintain vascular integrity during postnatal development of the central nervous system. PloS One 2012, 7:e39336.
    • (2012) PloS One , vol.7
    • Allinson, K.R.1    Lee, H.S.2    Fruttiger, M.3    McCarty, J.4    Arthur, H.M.5
  • 39
    • 84856284021 scopus 로고    scopus 로고
    • Defective retinal vascular endothelial cell development as a consequence of impaired integrin αVΒ8-mediated activation of transforming growth factor-Β
    • Arnold T.D., Ferrero G.M., Qiu H., Phan I.T., Akhurst R.J., Huang E.J., Reichardt L.F. Defective retinal vascular endothelial cell development as a consequence of impaired integrin αVΒ8-mediated activation of transforming growth factor-Β. J. Neurosci.: Off. J. Soc. Neurosci. 2012, 32:1197-1206.
    • (2012) J. Neurosci.: Off. J. Soc. Neurosci. , vol.32 , pp. 1197-1206
    • Arnold, T.D.1    Ferrero, G.M.2    Qiu, H.3    Phan, I.T.4    Akhurst, R.J.5    Huang, E.J.6    Reichardt, L.F.7
  • 43
    • 33748542875 scopus 로고    scopus 로고
    • A critical developmental role for tgfbr2 in myogenic cell lineages is revealed in mice expressing SM22-Cre, not SMMHC-Cre
    • Frutkin A.D., Shi H., Otsuka G., Levéen P., Karlsson S., Dichek D.a. A critical developmental role for tgfbr2 in myogenic cell lineages is revealed in mice expressing SM22-Cre, not SMMHC-Cre. J. Mol. Cell Cardiol. 2006, 41:724-731.
    • (2006) J. Mol. Cell Cardiol. , vol.41 , pp. 724-731
    • Frutkin, A.D.1    Shi, H.2    Otsuka, G.3    Levéen, P.4    Karlsson, S.5    Dichek, D.6
  • 44
    • 78149464338 scopus 로고    scopus 로고
    • Conditional inactivation of TGF-Β type II receptor in smooth muscle cells and epicardium causes lethal aortic and cardiac defects
    • Langlois D., Hneino M., Bouazza L., Parlakian A., Sasaki T., Bricca G., Li J.Y. Conditional inactivation of TGF-Β type II receptor in smooth muscle cells and epicardium causes lethal aortic and cardiac defects. Transgenic Res. 2010, 19:1069-1082.
    • (2010) Transgenic Res. , vol.19 , pp. 1069-1082
    • Langlois, D.1    Hneino, M.2    Bouazza, L.3    Parlakian, A.4    Sasaki, T.5    Bricca, G.6    Li, J.Y.7
  • 45
  • 46
    • 53349108638 scopus 로고    scopus 로고
    • SM22alpha-targeted deletion of bone morphogenetic protein receptor 1A in mice impairs cardiac and vascular development, and influences organogenesis
    • El-Bizri N., Guignabert C., Wang L., Cheng A., Stankunas K., Chang C.-P., Mishina Y., Rabinovitch M. SM22alpha-targeted deletion of bone morphogenetic protein receptor 1A in mice impairs cardiac and vascular development, and influences organogenesis. Development 2008, 135:2981-2991.
    • (2008) Development , vol.135 , pp. 2981-2991
    • El-Bizri, N.1    Guignabert, C.2    Wang, L.3    Cheng, A.4    Stankunas, K.5    Chang, C.-P.6    Mishina, Y.7    Rabinovitch, M.8
  • 47
    • 33144462810 scopus 로고    scopus 로고
    • Hereditary haemorrhagic telangiectasia: current views on genetics and mechanisms of disease
    • Abdalla S.A., Letarte M. Hereditary haemorrhagic telangiectasia: current views on genetics and mechanisms of disease. J. Med. Genet. 2006, 43:97-110.
    • (2006) J. Med. Genet. , vol.43 , pp. 97-110
    • Abdalla, S.A.1    Letarte, M.2
  • 52
    • 0034970744 scopus 로고    scopus 로고
    • Potential role of modifier genes influencing transforming growth factor-beta1 levels in the development of vascular defects in endoglin heterozygous mice with hereditary hemorrhagic telangiectasia
    • Bourdeau A., Faughnan M.E., McDonald M.L., Paterson A.D., Wanless I.R., Letarte M. Potential role of modifier genes influencing transforming growth factor-beta1 levels in the development of vascular defects in endoglin heterozygous mice with hereditary hemorrhagic telangiectasia. Am. J. Pathol. 2001, 158:2011-2020.
    • (2001) Am. J. Pathol. , vol.158 , pp. 2011-2020
    • Bourdeau, A.1    Faughnan, M.E.2    McDonald, M.L.3    Paterson, A.D.4    Wanless, I.R.5    Letarte, M.6
  • 57
    • 78649726867 scopus 로고    scopus 로고
    • Quantitative analysis of TGFBR2 mutations in Marfan-syndrome-related disorders suggests a correlation between phenotypic severity and Smad signaling activity
    • Horbelt D., Guo G., Robinson P.N., Knaus P. Quantitative analysis of TGFBR2 mutations in Marfan-syndrome-related disorders suggests a correlation between phenotypic severity and Smad signaling activity. J. Cell Sci. 2010, 123:4340-4350.
    • (2010) J. Cell Sci. , vol.123 , pp. 4340-4350
    • Horbelt, D.1    Guo, G.2    Robinson, P.N.3    Knaus, P.4
  • 58
    • 84866985855 scopus 로고    scopus 로고
    • Targeting the TGFbeta signaling pathway in disease
    • Akhurst R.J., Hata A. Targeting the TGFbeta signaling pathway in disease. Nat. Rev. Drug Discovery 2012, 11:790-811.
    • (2012) Nat. Rev. Drug Discovery , vol.11 , pp. 790-811
    • Akhurst, R.J.1    Hata, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.