-
1
-
-
84855172814
-
The pathogenesis of rheumatoid arthritis
-
McInnes, I. B., Schett, G. (2011) The pathogenesis of rheumatoid arthritis. N. Engl. J. Med. 365, 2205-2219.
-
(2011)
N. Engl. J. Med.
, vol.365
, pp. 2205-2219
-
-
McInnes, I.B.1
Schett, G.2
-
2
-
-
79955824880
-
Fcγ receptor profile of monocytes and macrophages from rheumatoid arthritis patients and their response to immune complexes formed with autoantibodies to citrullinated proteins
-
Laurent, L., Clavel, C., Lemaire, O., Anquetil, F., Cornillet, M., Zabraniecki, L., Nogueira, L., Fournie, B., Serre, G., Sebbag, M. (2011) Fcγ receptor profile of monocytes and macrophages from rheumatoid arthritis patients and their response to immune complexes formed with autoantibodies to citrullinated proteins. Ann. Rheum. Dis. 70, 1052-1059.
-
(2011)
Ann. Rheum. Dis.
, vol.70
, pp. 1052-1059
-
-
Laurent, L.1
Clavel, C.2
Lemaire, O.3
Anquetil, F.4
Cornillet, M.5
Zabraniecki, L.6
Nogueira, L.7
Fournie, B.8
Serre, G.9
Sebbag, M.10
-
3
-
-
78650779270
-
Immune complexes containing citrullinated fibrinogen costimulate macrophages via Toll-like receptor 4 and Fcγ receptor
-
Sokolove, J., Zhao, X., Chandra, P. E., Robinson, W. H. (2011) Immune complexes containing citrullinated fibrinogen costimulate macrophages via Toll-like receptor 4 and Fcγ receptor. Arthritis Rheum. 63, 53-62.
-
(2011)
Arthritis Rheum.
, vol.63
, pp. 53-62
-
-
Sokolove, J.1
Zhao, X.2
Chandra, P.E.3
Robinson, W.H.4
-
4
-
-
51249085423
-
Circulating immune complexes contain citrullinated fibrinogen in rheumatoid arthritis
-
Zhao, X., Okeke, N. L., Sharpe, O., Batliwalla, F. M., Lee, A. T., Ho, P. P., Tomooka, B. H., Gregersen, P. K., Robinson, W. H. (2008) Circulating immune complexes contain citrullinated fibrinogen in rheumatoid arthritis. Arthritis Res. Ther. 10, R94.
-
(2008)
Arthritis Res. Ther.
, vol.10
-
-
Zhao, X.1
Okeke, N.L.2
Sharpe, O.3
Batliwalla, F.M.4
Lee, A.T.5
Ho, P.P.6
Tomooka, B.H.7
Gregersen, P.K.8
Robinson, W.H.9
-
5
-
-
67650065027
-
Anti-cyclic citrullinated peptide antibodies from rheumatoid arthritis patients activate complement via both the classical and alternative pathways
-
Trouw, L. A., Haisma, E. M., Levarht, E. W., van der Woude, D., Ioan-Facsinay, A., Daha, M. R., Huizinga, T. W., Toes, R. E. (2009) Anti-cyclic citrullinated peptide antibodies from rheumatoid arthritis patients activate complement via both the classical and alternative pathways. Arthritis Rheum. 60, 1923-1931.
-
(2009)
Arthritis Rheum.
, vol.60
, pp. 1923-1931
-
-
Trouw, L.A.1
Haisma, E.M.2
Levarht, E.W.3
van der Woude, D.4
Ioan-Facsinay, A.5
Daha, M.R.6
Huizinga, T.W.7
Toes, R.E.8
-
6
-
-
33845506003
-
Long-term impact of early treatment on radiographic progression in rheumatoid arthritis: A meta-analysis
-
Finckh, A., Liang, M. H., van Herckenrode, C. M., de Pablo, P. (2006) Long-term impact of early treatment on radiographic progression in rheumatoid arthritis: a meta-analysis. Arthritis Rheum. 55, 864-872.
-
(2006)
Arthritis Rheum.
, vol.55
, pp. 864-872
-
-
Finckh, A.1
Liang, M.H.2
van Herckenrode, C.M.3
de Pablo, P.4
-
7
-
-
84860920048
-
Combination etanercept and methotrexate provides better disease control in very early (<=4 months) versus early rheumatoid arthritis (>4 months and <2 years): Post hoc analyses from the COMET study
-
Emery, P., Kvien, T. K., Combe, B., Freundlich, B., Robertson, D., Ferdousi, T., Bananis, E., Pedersen, R., Koenig, A. S. (2012) Combination etanercept and methotrexate provides better disease control in very early (<=4 months) versus early rheumatoid arthritis (>4 months and <2 years): post hoc analyses from the COMET study. Ann. Rheum. Dis. 71, 989-992.
-
(2012)
Ann. Rheum. Dis.
, vol.71
, pp. 989-992
-
-
Emery, P.1
Kvien, T.K.2
Combe, B.3
Freundlich, B.4
Robertson, D.5
Ferdousi, T.6
Bananis, E.7
Pedersen, R.8
Koenig, A.S.9
-
8
-
-
77956416903
-
Toll-like receptor signaling: A potential link among rheumatoid arthritis, systemic lupus, and atherosclerosis
-
Huang, Q., Pope, R. M. (2010) Toll-like receptor signaling: a potential link among rheumatoid arthritis, systemic lupus, and atherosclerosis. J. Leukoc. Biol. 88, 253-262.
-
(2010)
J. Leukoc. Biol.
, vol.88
, pp. 253-262
-
-
Huang, Q.1
Pope, R.M.2
-
9
-
-
70449625015
-
The role of Toll-like receptors in rheumatoid arthritis
-
Huang, Q. Q., Pope, R. M. (2009) The role of Toll-like receptors in rheumatoid arthritis. Curr. Rheumatol. Rep. 11, 357-364.
-
(2009)
Curr. Rheumatol. Rep.
, vol.11
, pp. 357-364
-
-
Huang, Q.Q.1
Pope, R.M.2
-
10
-
-
34547450707
-
Increased macrophage activation mediated through Toll-like receptors in rheumatoid arthritis
-
Huang, Q., Ma, Y., Adebayo, A., Pope, R. M. (2007) Increased macrophage activation mediated through Toll-like receptors in rheumatoid arthritis. Arthritis Rheum. 56, 2192-2201.
-
(2007)
Arthritis Rheum.
, vol.56
, pp. 2192-2201
-
-
Huang, Q.1
Ma, Y.2
Adebayo, A.3
Pope, R.M.4
-
11
-
-
65249190995
-
Heat shock protein 96 is elevated in rheumatoid arthritis and activates macrophages primarily via TLR2 signaling
-
Huang, Q. Q., Sobkoviak, R., Jockheck-Clark, A. R., Shi, B., Mandelin 2nd, A. M., Tak, P. P., Haines 3rd, G. K., Nicchitta, C. V., Pope, R. M. (2009) Heat shock protein 96 is elevated in rheumatoid arthritis and activates macrophages primarily via TLR2 signaling. J. Immunol. 182, 4965-4973.
-
(2009)
J. Immunol.
, vol.182
, pp. 4965-4973
-
-
Huang, Q.Q.1
Sobkoviak, R.2
Jockheck-Clark, A.R.3
Shi, B.4
Mandelin II, A.M.5
Tak, P.P.6
Haines III, G.K.7
Nicchitta, C.V.8
Pope, R.M.9
-
12
-
-
84863847170
-
SNAPIN: An endogenous Toll-like receptor ligand in rheumatoid arthritis
-
Shi, B., Huang, Q., Tak, P. P., Vervoordeldonk, M. J., Huang, C. C., Dorfleutner, A., Stehlik, C., Pope, R. M. (2012) SNAPIN: an endogenous Toll-like receptor ligand in rheumatoid arthritis. Ann. Rheum. Dis. 71, 1411-1417.
-
(2012)
Ann. Rheum. Dis.
, vol.71
, pp. 1411-1417
-
-
Shi, B.1
Huang, Q.2
Tak, P.P.3
Vervoordeldonk, M.J.4
Huang, C.C.5
Dorfleutner, A.6
Stehlik, C.7
Pope, R.M.8
-
13
-
-
84868146602
-
Gp96 perpetuates the persistent inflammation of rheumatoid arthritis
-
Huang, Q. Q., Koessler, R. E., Birkett, R., Dorfleutner, A., Perlman, H., Kenneth Haines 3rd, G., Stehlik, C., Nicchitta, C. V., Pope, R. M. (2012) Gp96 perpetuates the persistent inflammation of rheumatoid arthritis. Arthritis Rheum. 64, 3638-3648.
-
(2012)
Arthritis Rheum.
, vol.64
, pp. 3638-3648
-
-
Huang, Q.Q.1
Koessler, R.E.2
Birkett, R.3
Dorfleutner, A.4
Perlman, H.5
Kenneth Haines III, G.6
Stehlik, C.7
Nicchitta, C.V.8
Pope, R.M.9
-
14
-
-
38149048556
-
Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis
-
Abdollahi-Roodsaz, S., Joosten, L. A., Koenders, M. I., Devesa, I., Roelofs, M. F., Radstake, T. R., Heuvelmans-Jacobs, M., Akira, S., Nicklin, M. J., Ribeiro-Dias, F., van den Berg, W. B. (2008) Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis. J. Clin. Invest. 118, 205-216.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 205-216
-
-
Abdollahi-Roodsaz, S.1
Joosten, L.A.2
Koenders, M.I.3
Devesa, I.4
Roelofs, M.F.5
Radstake, T.R.6
Heuvelmans-Jacobs, M.7
Akira, S.8
Nicklin, M.J.9
Ribeiro-Dias, F.10
van den Berg, W.B.11
-
15
-
-
73649088291
-
Local interleukin-1-driven joint pathology is dependent on Toll-like receptor 4 activation
-
Abdollahi-Roodsaz, S., Joosten, L. A., Koenders, M. I., van den Brand, B. T., van de Loo, F. A., van den Berg, W. B. (2009) Local interleukin-1-driven joint pathology is dependent on Toll-like receptor 4 activation. Am. J. Pathol. 175, 2004-2013.
-
(2009)
Am. J. Pathol.
, vol.175
, pp. 2004-2013
-
-
Abdollahi-Roodsaz, S.1
Joosten, L.A.2
Koenders, M.I.3
van den Brand, B.T.4
van de Loo, F.A.5
van den Berg, W.B.6
-
16
-
-
77649184739
-
The regulation of IL-10 production by immune cells
-
Saraiva, M., O'Garra, A. (2010) The regulation of IL-10 production by immune cells. Nat. Rev. Immunol. 10, 170-181.
-
(2010)
Nat. Rev. Immunol.
, vol.10
, pp. 170-181
-
-
Saraiva, M.1
O'Garra, A.2
-
17
-
-
0033118675
-
From systemic T cell self-reactivity to organ-specific autoimmune disease via immunoglobulins
-
Korganow, A. S., Ji, H., Mangialaio, S., Duchatelle, V., Pelanda, R., Martin, T., Degott, C., Kikutani, H., Rajewsky, K., Pasquali, J. L., Benoist, C., Mathis, D. (1999) From systemic T cell self-reactivity to organ-specific autoimmune disease via immunoglobulins. Immunity 10, 451-461.
-
(1999)
Immunity
, vol.10
, pp. 451-461
-
-
Korganow, A.S.1
Ji, H.2
Mangialaio, S.3
Duchatelle, V.4
Pelanda, R.5
Martin, T.6
Degott, C.7
Kikutani, H.8
Rajewsky, K.9
Pasquali, J.L.10
Benoist, C.11
Mathis, D.12
-
18
-
-
34347219754
-
Pro-apoptotic Bid is required for the resolution of the effector phase of inflammatory arthritis
-
Scatizzi, J. C., Hutcheson, J., Bickel, E., Haines 3rd, G. K., Perlman, H. (2007) Pro-apoptotic Bid is required for the resolution of the effector phase of inflammatory arthritis. Arthritis Res. Ther. 9, R49.
-
(2007)
Arthritis Res. Ther.
, vol.9
-
-
Scatizzi, J.C.1
Hutcheson, J.2
Bickel, E.3
Haines III, G.K.4
Perlman, H.5
-
19
-
-
75749091858
-
Bim-Bcl-2 homology 3 mimetic therapy is effective at suppressing inflammatory arthritis through the activation of myeloid cell apoptosis
-
Scatizzi, J. C., Hutcheson, J., Pope, R. M., Firestein, G. S., Koch, A. E., Mavers, M., Smason, A., Agrawal, H., Haines 3rd, G. K., Chandel, N. S., Hotchkiss, R. S., Perlman, H. (2010) Bim-Bcl-2 homology 3 mimetic therapy is effective at suppressing inflammatory arthritis through the activation of myeloid cell apoptosis. Arthritis Rheum. 62, 441-451.
-
(2010)
Arthritis Rheum.
, vol.62
, pp. 441-451
-
-
Scatizzi, J.C.1
Hutcheson, J.2
Pope, R.M.3
Firestein, G.S.4
Koch, A.E.5
Mavers, M.6
Smason, A.7
Agrawal, H.8
Haines III, G.K.9
Chandel, N.S.10
Hotchkiss, R.S.11
Perlman, H.12
-
20
-
-
25444472565
-
Tumor necrosis factor prevents alendronate-induced osteoclast apoptosis in vivo by stimulating Bcl-xL expression through Ets-2
-
Zhang, Q., Badell, I. R., Schwarz, E. M., Boulukos, K. E., Yao, Z., Boyce, B. F., Xing, L. (2005) Tumor necrosis factor prevents alendronate-induced osteoclast apoptosis in vivo by stimulating Bcl-xL expression through Ets-2. Arthritis Rheum. 52, 2708-2718.
-
(2005)
Arthritis Rheum.
, vol.52
, pp. 2708-2718
-
-
Zhang, Q.1
Badell, I.R.2
Schwarz, E.M.3
Boulukos, K.E.4
Yao, Z.5
Boyce, B.F.6
Xing, L.7
-
21
-
-
84855202439
-
Anti-CXCL5 therapy ameliorates IL-17-induced arthritis by decreasing joint vascularization
-
Pickens, S. R., Chamberlain, N. D., Volin, M. V., Gonzalez, M., Pope, R. M., Mandelin 2nd, A. M., Kolls, J. K., Shahrara, S. (2011) Anti-CXCL5 therapy ameliorates IL-17-induced arthritis by decreasing joint vascularization. Angiogenesis 14, 443-455.
-
(2011)
Angiogenesis
, vol.14
, pp. 443-455
-
-
Pickens, S.R.1
Chamberlain, N.D.2
Volin, M.V.3
Gonzalez, M.4
Pope, R.M.5
Mandelin II, A.M.6
Kolls, J.K.7
Shahrara, S.8
-
22
-
-
77956954197
-
The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection
-
Satoh, T., Takeuchi, O., Vandenbon, A., Yasuda, K., Tanaka, Y., Kumagai, Y., Miyake, T., Matsushita, K., Okazaki, T., Saitoh, T., Honma, K., Matsuyama, T., Yui, K., Tsujimura, T., Standley, D. M., Nakanishi, K., Nakai, K., Akira, S. (2010) The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection. Nat. Immunol. 11, 936-944.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 936-944
-
-
Satoh, T.1
Takeuchi, O.2
Vandenbon, A.3
Yasuda, K.4
Tanaka, Y.5
Kumagai, Y.6
Miyake, T.7
Matsushita, K.8
Okazaki, T.9
Saitoh, T.10
Honma, K.11
Matsuyama, T.12
Yui, K.13
Tsujimura, T.14
Standley, D.M.15
Nakanishi, K.16
Nakai, K.17
Akira, S.18
-
23
-
-
77950496491
-
Fcγ receptor cross-linking stimulates cell proliferation of macrophages via the ERK pathway
-
Luo, Y., Pollard, J. W., Casadevall, A. (2010) Fcγ receptor cross-linking stimulates cell proliferation of macrophages via the ERK pathway. J. Biol. Chem. 285, 4232-4242.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 4232-4242
-
-
Luo, Y.1
Pollard, J.W.2
Casadevall, A.3
-
24
-
-
40849145437
-
Insoluble immune complexes are most effective at triggering IL-10 production in human monocytes and synergize with TLR ligands and C5a
-
DiMartino, S. J., Yuan, W., Redecha, P., Ivashkiv, L. B., Salmon, J. E. (2008) Insoluble immune complexes are most effective at triggering IL-10 production in human monocytes and synergize with TLR ligands and C5a. Clin. Immunol. 127, 56-65.
-
(2008)
Clin. Immunol.
, vol.127
, pp. 56-65
-
-
DiMartino, S.J.1
Yuan, W.2
Redecha, P.3
Ivashkiv, L.B.4
Salmon, J.E.5
-
25
-
-
78649731663
-
FLIP: A novel regulator of macrophage differentiation and granulocyte homeostasis
-
Huang, Q. Q., Perlman, H., Huang, Z., Birkett, R., Kan, L., Agrawal, H., Misharin, A., Gurbuxani, S., Crispino, J. D., Pope, R. M. (2010) FLIP: a novel regulator of macrophage differentiation and granulocyte homeostasis. Blood 116, 4968-4977.
-
(2010)
Blood
, vol.116
, pp. 4968-4977
-
-
Huang, Q.Q.1
Perlman, H.2
Huang, Z.3
Birkett, R.4
Kan, L.5
Agrawal, H.6
Misharin, A.7
Gurbuxani, S.8
Crispino, J.D.9
Pope, R.M.10
-
26
-
-
70149090443
-
IL-10 suppresses calcium-mediated costimulation of receptor activator NF-κ B signaling during human osteoclast differentiation by inhibiting TREM-2 expression
-
Park-Min, K. H., Ji, J. D., Antoniv, T., Reid, A. C., Silver, R. B., Humphrey, M. B., Nakamura, M., Ivashkiv, L. B. (2009) IL-10 suppresses calcium-mediated costimulation of receptor activator NF-κ B signaling during human osteoclast differentiation by inhibiting TREM-2 expression. J. Immunol. 183, 2444-2455.
-
(2009)
J. Immunol.
, vol.183
, pp. 2444-2455
-
-
Park-Min, K.H.1
Ji, J.D.2
Antoniv, T.3
Reid, A.C.4
Silver, R.B.5
Humphrey, M.B.6
Nakamura, M.7
Ivashkiv, L.B.8
-
27
-
-
33845194659
-
Enhanced osteoclastogenesis in 4-1BB-deficient mice caused by reduced interleukin-10
-
Shin, H. H., Lee, J. E., Lee, E. A., Kwon, B. S., Choi, H. S. (2006) Enhanced osteoclastogenesis in 4-1BB-deficient mice caused by reduced interleukin-10. J. Bone Miner. Res. 21, 1907-1912.
-
(2006)
J. Bone Miner. Res.
, vol.21
, pp. 1907-1912
-
-
Shin, H.H.1
Lee, J.E.2
Lee, E.A.3
Kwon, B.S.4
Choi, H.S.5
-
28
-
-
0032796339
-
Different modes of pathogenesis in T-cell-dependent autoimmunity: Clues from two TCR transgenic systems
-
Ji, H., Korganow, A. S., Mangialaio, S., Hoglund, P., Andre, I., Luhder, F., Gonzalez, A., Poirot, L., Benoist, C., Mathis, D. (1999) Different modes of pathogenesis in T-cell-dependent autoimmunity: clues from two TCR transgenic systems. Immunol. Rev. 169, 139-146.
-
(1999)
Immunol. Rev.
, vol.169
, pp. 139-146
-
-
Ji, H.1
Korganow, A.S.2
Mangialaio, S.3
Hoglund, P.4
Andre, I.5
Luhder, F.6
Gonzalez, A.7
Poirot, L.8
Benoist, C.9
Mathis, D.10
-
29
-
-
33646505131
-
p21Cip1 is required for the development of monocytes and their response to serum transfer-induced arthritis
-
Scatizzi, J. C., Hutcheson, J., Bickel, E., Woods, J. M., Klosowska, K., Moore, T. L., Haines 3rd, G. K., Perlman, H. (2006) p21Cip1 is required for the development of monocytes and their response to serum transfer-induced arthritis. Am. J. Pathol. 168, 1531-1541.
-
(2006)
Am. J. Pathol.
, vol.168
, pp. 1531-1541
-
-
Scatizzi, J.C.1
Hutcheson, J.2
Bickel, E.3
Woods, J.M.4
Klosowska, K.5
Moore, T.L.6
Haines III, G.K.7
Perlman, H.8
-
30
-
-
23444437045
-
Local inflammation as a mediator of migraine and tension-type headache: A response
-
Solomon, S. (2005) Local inflammation as a mediator of migraine and tension-type headache: a response. Headache 45, 255.
-
(2005)
Headache
, vol.45
, pp. 255
-
-
Solomon, S.1
-
31
-
-
0036884551
-
The role of FcγR signaling in the K/B x N serum transfer model of arthritis
-
Corr, M., Crain, B. (2002) The role of FcγR signaling in the K/B x N serum transfer model of arthritis. J. Immunol. 169, 6604-6609.
-
(2002)
J. Immunol.
, vol.169
, pp. 6604-6609
-
-
Corr, M.1
Crain, B.2
-
32
-
-
27644470548
-
A crucial role for macrophages in the pathology of K/B x N serum-induced arthritis
-
Solomon, S., Rajasekaran, N., Jeisy-Walder, E., Snapper, S. B., Illges, H. (2005) A crucial role for macrophages in the pathology of K/B x N serum-induced arthritis. Eur. J. Immunol. 35, 3064-3073.
-
(2005)
Eur. J. Immunol.
, vol.35
, pp. 3064-3073
-
-
Solomon, S.1
Rajasekaran, N.2
Jeisy-Walder, E.3
Snapper, S.B.4
Illges, H.5
-
33
-
-
18344365948
-
Arthritis critically dependent on innate immune system players
-
Ji, H., Ohmura, K., Mahmood, U., Lee, D. M., Hofhuis, F. M., Boackle, S. A., Takahashi, K., Holers, V. M., Walport, M., Gerard, C., Ezekowitz, A., Carroll, M. C., Brenner, M., Weissleder, R., Verbeek, J. S., Duchatelle, V., Degott, C., Benoist, C., Mathis, D. (2002) Arthritis critically dependent on innate immune system players. Immunity 16, 157-168.
-
(2002)
Immunity
, vol.16
, pp. 157-168
-
-
Ji, H.1
Ohmura, K.2
Mahmood, U.3
Lee, D.M.4
Hofhuis, F.M.5
Boackle, S.A.6
Takahashi, K.7
Holers, V.M.8
Walport, M.9
Gerard, C.10
Ezekowitz, A.11
Carroll, M.C.12
Brenner, M.13
Weissleder, R.14
Verbeek, J.S.15
Duchatelle, V.16
Degott, C.17
Benoist, C.18
Mathis, D.19
-
34
-
-
2942625705
-
Staging the initiation of autoantibody-induced arthritis: A critical role for immune complexes
-
Wipke, B. T., Wang, Z., Nagengast, W., Reichert, D. E., Allen, P. M. (2004) Staging the initiation of autoantibody-induced arthritis: a critical role for immune complexes. J. Immunol. 172, 7694-7702.
-
(2004)
J. Immunol.
, vol.172
, pp. 7694-7702
-
-
Wipke, B.T.1
Wang, Z.2
Nagengast, W.3
Reichert, D.E.4
Allen, P.M.5
-
35
-
-
0034677123
-
Development of chronic inflammatory arthropathy resembling rheumatoid arthritis in interleukin 1 receptor antagonist-deficient mice
-
Horai, R., Saijo, S., Tanioka, H., Nakae, S., Sudo, K., Okahara, A., Ikuse, T., Asano, M., Iwakura, Y. (2000) Development of chronic inflammatory arthropathy resembling rheumatoid arthritis in interleukin 1 receptor antagonist-deficient mice. J. Exp. Med. 191, 313-320.
-
(2000)
J. Exp. Med.
, vol.191
, pp. 313-320
-
-
Horai, R.1
Saijo, S.2
Tanioka, H.3
Nakae, S.4
Sudo, K.5
Okahara, A.6
Ikuse, T.7
Asano, M.8
Iwakura, Y.9
-
36
-
-
0038623916
-
IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist
-
Nakae, S., Saijo, S., Horai, R., Sudo, K., Mori, S., Iwakura, Y. (2003) IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist. Proc. Natl. Acad. Sci. USA 100, 5986-5990.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 5986-5990
-
-
Nakae, S.1
Saijo, S.2
Horai, R.3
Sudo, K.4
Mori, S.5
Iwakura, Y.6
-
37
-
-
77950364465
-
Neutrophils in a mouse model of autoantibodymediated arthritis: Critical producers of Fc receptor γ, the receptor for C5a, and lymphocyte function-associated antigen 1
-
Monach, P. A., Nigrovic, P. A., Chen, M., Hock, H., Lee, D. M., Benoist, C., Mathis, D. (2010) Neutrophils in a mouse model of autoantibodymediated arthritis: critical producers of Fc receptor γ, the receptor for C5a, and lymphocyte function-associated antigen 1. Arthritis Rheum. 62, 753-764.
-
(2010)
Arthritis Rheum.
, vol.62
, pp. 753-764
-
-
Monach, P.A.1
Nigrovic, P.A.2
Chen, M.3
Hock, H.4
Lee, D.M.5
Benoist, C.6
Mathis, D.7
-
38
-
-
33847238479
-
Mast cells contribute to initiation of autoantibody-mediated arthritis via IL-1
-
Nigrovic, P. A., Binstadt, B. A., Monach, P. A., Johnsen, A., Gurish, M., Iwakura, Y., Benoist, C., Mathis, D., Lee, D. M. (2007) Mast cells contribute to initiation of autoantibody-mediated arthritis via IL-1. Proc. Natl. Acad. Sci. USA 104, 2325-2330.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 2325-2330
-
-
Nigrovic, P.A.1
Binstadt, B.A.2
Monach, P.A.3
Johnsen, A.4
Gurish, M.5
Iwakura, Y.6
Benoist, C.7
Mathis, D.8
Lee, D.M.9
-
39
-
-
79961114696
-
Regulation of systemic and local myeloid cell subpopulations by bone marrow cell-derived granulocyte-macrophage colonystimulating factor in experimental inflammatory arthritis
-
Cook, A. D., Turner, A. L., Braine, E. L., Pobjoy, J., Lenzo, J. C., Hamilton, J. A. (2011) Regulation of systemic and local myeloid cell subpopulations by bone marrow cell-derived granulocyte-macrophage colonystimulating factor in experimental inflammatory arthritis. Arthritis Rheum. 63, 2340-2351.
-
(2011)
Arthritis Rheum.
, vol.63
, pp. 2340-2351
-
-
Cook, A.D.1
Turner, A.L.2
Braine, E.L.3
Pobjoy, J.4
Lenzo, J.C.5
Hamilton, J.A.6
-
40
-
-
0028813787
-
Elevated interleukin-10 levels in patients with rheumatoid arthritis
-
Cush, J. J., Splawski, J. B., Thomas, R., McFarlin, J. E., Schulze-Koops, H., Davis, L. S., Fujita, K., Lipsky, P. E. (1995) Elevated interleukin-10 levels in patients with rheumatoid arthritis. Arthritis Rheum. 38, 96-104.
-
(1995)
Arthritis Rheum.
, vol.38
, pp. 96-104
-
-
Cush, J.J.1
Splawski, J.B.2
Thomas, R.3
McFarlin, J.E.4
Schulze-Koops, H.5
Davis, L.S.6
Fujita, K.7
Lipsky, P.E.8
-
41
-
-
0034862856
-
Interleukin 10 (IL-10), not IL-4 or interferon-γ production, correlates with progression of joint destruction in rheumatoid arthritis
-
Verhoef, C. M., van Roon, J. A., Vianen, M. E., Bijlsma, J. W., Lafeber, F. P. (2001) Interleukin 10 (IL-10), not IL-4 or interferon-γ production, correlates with progression of joint destruction in rheumatoid arthritis. J. Rheumatol. 28, 1960-1966.
-
(2001)
J. Rheumatol.
, vol.28
, pp. 1960-1966
-
-
Verhoef, C.M.1
van Roon, J.A.2
Vianen, M.E.3
Bijlsma, J.W.4
Lafeber, F.P.5
-
42
-
-
0028226993
-
Immunoregulatory role of interleukin 10 in rheumatoid arthritis
-
Katsikis, P. D., Chu, C. Q., Brennan, F. M., Maini, R. N., Feldmann, M. (1994) Immunoregulatory role of interleukin 10 in rheumatoid arthritis. J. Exp. Med. 179, 1517-1527.
-
(1994)
J. Exp. Med.
, vol.179
, pp. 1517-1527
-
-
Katsikis, P.D.1
Chu, C.Q.2
Brennan, F.M.3
Maini, R.N.4
Feldmann, M.5
-
43
-
-
0035884447
-
IL-10-deficient B10. Q mice develop more severe collagen-induced arthritis, but are protected from arthritis induced with antitype II collagen antibodies
-
Johansson, A. C., Hansson, A. S., Nandakumar, K. S., Backlund, J., Holmdahl, R. (2001) IL-10-deficient B10. Q mice develop more severe collagen-induced arthritis, but are protected from arthritis induced with antitype II collagen antibodies. J. Immunol. 167, 3505-3512.
-
(2001)
J. Immunol.
, vol.167
, pp. 3505-3512
-
-
Johansson, A.C.1
Hansson, A.S.2
Nandakumar, K.S.3
Backlund, J.4
Holmdahl, R.5
-
44
-
-
0141733605
-
Collagen-induced arthritis is exacerbated in IL-10-deficient mice
-
Finnegan, A., Kaplan, C. D., Cao, Y., Eibel, H., Glant, T. T., Zhang, J. (2003) Collagen-induced arthritis is exacerbated in IL-10-deficient mice. Arthritis Res. Ther. 5, R18-R24.
-
(2003)
Arthritis Res. Ther.
, vol.5
-
-
Finnegan, A.1
Kaplan, C.D.2
Cao, Y.3
Eibel, H.4
Glant, T.T.5
Zhang, J.6
-
45
-
-
0031059255
-
Role of interleukin-4 and interleukin-10 in murine collagen-induced arthritis. Protective effect of interleukin-4 and interleukin-10 treatment on cartilage destruction
-
Joosten, L. A., Lubberts, E., Durez, P., Helsen, M. M., Jacobs, M. J., Goldman, M., van den Berg, W. B. (1997) Role of interleukin-4 and interleukin-10 in murine collagen-induced arthritis. Protective effect of interleukin-4 and interleukin-10 treatment on cartilage destruction. Arthritis Rheum. 40, 249-260.
-
(1997)
Arthritis Rheum.
, vol.40
, pp. 249-260
-
-
Joosten, L.A.1
Lubberts, E.2
Durez, P.3
Helsen, M.M.4
Jacobs, M.J.5
Goldman, M.6
van den Berg, W.B.7
-
46
-
-
0034066110
-
Intraarticular IL-10 gene transfer regulates the expression of collagen-induced arthritis (CIA) in the knee and ipsilateral paw
-
Lubberts, E., Joosten, L. A., Van Den Bersselaar, L., Helsen, M. M., Bakker, A. C., Xing, Z., Richards, C. D., Van Den Berg, W. B. (2000) Intraarticular IL-10 gene transfer regulates the expression of collagen-induced arthritis (CIA) in the knee and ipsilateral paw. Clin. Exp. Immunol. 120, 375-383.
-
(2000)
Clin. Exp. Immunol.
, vol.120
, pp. 375-383
-
-
Lubberts, E.1
Joosten, L.A.2
van den Bersselaar, L.3
Helsen, M.M.4
Bakker, A.C.5
Xing, Z.6
Richards, C.D.7
van den Berg, W.B.8
-
47
-
-
0029796835
-
Interleukin-10 suppresses the development of collagen type IIinduced arthritis and ameliorates sustained arthritis in rats
-
Persson, S., Mikulowska, A., Narula, S., O'Garra, A., Holmdahl, R. (1996) Interleukin-10 suppresses the development of collagen type IIinduced arthritis and ameliorates sustained arthritis in rats. Scand J. Immunol. 44, 607-614.
-
(1996)
Scand J. Immunol.
, vol.44
, pp. 607-614
-
-
Persson, S.1
Mikulowska, A.2
Narula, S.3
O'Garra, A.4
Holmdahl, R.5
-
48
-
-
0033559906
-
Adenoviral transfer of the viral IL-10 gene periarticularly to mouse paws suppresses development of collagen-induced arthritis in both injected and uninjected paws
-
Whalen, J. D., Lechman, E. L., Carlos, C. A., Weiss, K., Kovesdi, I., Glorioso, J. C., Robbins, P. D., Evans, C. H. (1999) Adenoviral transfer of the viral IL-10 gene periarticularly to mouse paws suppresses development of collagen-induced arthritis in both injected and uninjected paws. J. Immunol. 162, 3625-3632.
-
(1999)
J. Immunol.
, vol.162
, pp. 3625-3632
-
-
Whalen, J.D.1
Lechman, E.L.2
Carlos, C.A.3
Weiss, K.4
Kovesdi, I.5
Glorioso, J.C.6
Robbins, P.D.7
Evans, C.H.8
-
49
-
-
0029944882
-
IL-10 modulates formation of osteoclasts in murine hemopoietic cultures
-
Owens, J. M., Gallagher, A. C., Chambers, T. J. (1996) IL-10 modulates formation of osteoclasts in murine hemopoietic cultures. J. Immunol. 157, 936-940.
-
(1996)
J. Immunol.
, vol.157
, pp. 936-940
-
-
Owens, J.M.1
Gallagher, A.C.2
Chambers, T.J.3
-
50
-
-
0034292422
-
IL-10, but not IL-4, suppresses infection-stimulated bone resorption in vivo
-
Sasaki, H., Hou, L., Belani, A., Wang, C. Y., Uchiyama, T., Muller, R., Stashenko, P. (2000) IL-10, but not IL-4, suppresses infection-stimulated bone resorption in vivo. J. Immunol. 165, 3626-3630.
-
(2000)
J. Immunol.
, vol.165
, pp. 3626-3630
-
-
Sasaki, H.1
Hou, L.2
Belani, A.3
Wang, C.Y.4
Uchiyama, T.5
Muller, R.6
Stashenko, P.7
-
51
-
-
33846785197
-
Interleukin-10 inhibits osteoclastogenesis by reducing NFATc1 expression and preventing its translocation to the nucleus
-
Evans, K. E., Fox, S. W. (2007) Interleukin-10 inhibits osteoclastogenesis by reducing NFATc1 expression and preventing its translocation to the nucleus. BMC Cell Biol. 8, 4.
-
(2007)
BMC Cell Biol.
, vol.8
, pp. 4
-
-
Evans, K.E.1
Fox, S.W.2
-
52
-
-
34548533322
-
Interleukin-10 inhibits RANKL-mediated expression of NFATc1 in part via suppression of c-Fos and c-Jun in RAW264.7 cells and mouse bone marrow cells
-
Mohamed, S. G., Sugiyama, E., Shinoda, K., Taki, H., Hounoki, H., Abdel-Aziz, H. O., Maruyama, M., Kobayashi, M., Ogawa, H., Miyahara, T. (2007) Interleukin-10 inhibits RANKL-mediated expression of NFATc1 in part via suppression of c-Fos and c-Jun in RAW264.7 cells and mouse bone marrow cells. Bone 41, 592-602.
-
(2007)
Bone
, vol.41
, pp. 592-602
-
-
Mohamed, S.G.1
Sugiyama, E.2
Shinoda, K.3
Taki, H.4
Hounoki, H.5
Abdel-Aziz, H.O.6
Maruyama, M.7
Kobayashi, M.8
Ogawa, H.9
Miyahara, T.10
-
53
-
-
0034577944
-
Toll-like receptor 2-mediated NF-κ B activation requires a Rac1-dependent pathway
-
Arbibe, L., Mira, J. P., Teusch, N., Kline, L., Guha, M., Mackman, N., Godowski, P. J., Ulevitch, R. J., Knaus, U. G. (2000) Toll-like receptor 2-mediated NF-κ B activation requires a Rac1-dependent pathway. Nat. Immunol. 1, 533-540.
-
(2000)
Nat. Immunol.
, vol.1
, pp. 533-540
-
-
Arbibe, L.1
Mira, J.P.2
Teusch, N.3
Kline, L.4
Guha, M.5
McKman, N.6
Godowski, P.J.7
Ulevitch, R.J.8
Knaus, U.G.9
-
54
-
-
80051632188
-
TLR2 ligand induces protection against cerebral ischemia/reperfusion injury via activation of phosphoinositide 3-kinase/Akt signaling
-
Lu, C., Liu, L., Chen, Y., Ha, T., Kelley, J., Schweitzer, J., Kalbfleisch, J. H., Kao, R. L., Williams, D. L., Li, C. (2011) TLR2 ligand induces protection against cerebral ischemia/reperfusion injury via activation of phosphoinositide 3-kinase/Akt signaling. J. Immunol. 187, 1458-1466.
-
(2011)
J. Immunol.
, vol.187
, pp. 1458-1466
-
-
Lu, C.1
Liu, L.2
Chen, Y.3
Ha, T.4
Kelley, J.5
Schweitzer, J.6
Kalbfleisch, J.H.7
Kao, R.L.8
Williams, D.L.9
Li, C.10
-
55
-
-
60949089460
-
Rac1 regulates peptidoglycan-induced nuclear factor-κB activation and cyclooxygenase-2 expression in RAW 264.7 macrophages by activating the phosphatidylinositol 3-kinase/Akt pathway
-
Chen, B. C., Kang, J. C., Lu, Y. T., Hsu, M. J., Liao, C. C., Chiu, W. T., Yeh, F. L., Lin, C. H. (2009) Rac1 regulates peptidoglycan-induced nuclear factor-κB activation and cyclooxygenase-2 expression in RAW 264.7 macrophages by activating the phosphatidylinositol 3-kinase/Akt pathway. Mol. Immunol. 46, 1179-1188.
-
(2009)
Mol. Immunol.
, vol.46
, pp. 1179-1188
-
-
Chen, B.C.1
Kang, J.C.2
Lu, Y.T.3
Hsu, M.J.4
Liao, C.C.5
Chiu, W.T.6
Yeh, F.L.7
Lin, C.H.8
-
56
-
-
2442676378
-
Peptidoglycan induces nuclear factor-κB activation and cyclooxygenase-2 expression via Ras, Raf-1, and ERK in RAW 264.7 macrophages
-
Chen, B. C., Chang, Y. S., Kang, J. C., Hsu, M. J., Sheu, J. R., Chen, T. L., Teng, C. M., Lin, C. H. (2004) Peptidoglycan induces nuclear factor-κB activation and cyclooxygenase-2 expression via Ras, Raf-1, and ERK in RAW 264.7 macrophages. J. Biol. Chem. 279, 20889-20897.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 20889-20897
-
-
Chen, B.C.1
Chang, Y.S.2
Kang, J.C.3
Hsu, M.J.4
Sheu, J.R.5
Chen, T.L.6
Teng, C.M.7
Lin, C.H.8
-
57
-
-
77957016117
-
The influence of IgG density and macrophage Fc (γ) receptor cross-linking on phagocytosis and IL-10 production
-
Gallo, P., Goncalves, R., Mosser, D. M. (2010) The influence of IgG density and macrophage Fc (γ) receptor cross-linking on phagocytosis and IL-10 production. Immunol. Lett. 133, 70-77.
-
(2010)
Immunol. Lett.
, vol.133
, pp. 70-77
-
-
Gallo, P.1
Goncalves, R.2
Mosser, D.M.3
-
58
-
-
33646595287
-
IFN-γ suppresses IL-10 production and synergizes with TLR2 by regulating GSK3 and CREB/AP-1 proteins
-
Hu, X., Paik, P. K., Chen, J., Yarilina, A., Kockeritz, L., Lu, T. T., Woodgett, J. R., Ivashkiv, L. B. (2006) IFN-γ suppresses IL-10 production and synergizes with TLR2 by regulating GSK3 and CREB/AP-1 proteins. Immunity 24, 563-574.
-
(2006)
Immunity
, vol.24
, pp. 563-574
-
-
Hu, X.1
Paik, P.K.2
Chen, J.3
Yarilina, A.4
Kockeritz, L.5
Lu, T.T.6
Woodgett, J.R.7
Ivashkiv, L.B.8
-
59
-
-
21244502077
-
ERK activation following macrophage FcγR ligation leads to chromatin modifications at the IL-10 locus
-
Lucas, M., Zhang, X., Prasanna, V., Mosser, D. M. (2005) ERK activation following macrophage FcγR ligation leads to chromatin modifications at the IL-10 locus. J. Immunol. 175, 469-477.
-
(2005)
J. Immunol.
, vol.175
, pp. 469-477
-
-
Lucas, M.1
Zhang, X.2
Prasanna, V.3
Mosser, D.M.4
-
60
-
-
79952532687
-
Interleukin-10-induced gene expression and suppressive function are selectively modulated by the PI3KAkt-GSK3 pathway
-
Antoniv, T. T., Ivashkiv, L. B. (2011) Interleukin-10-induced gene expression and suppressive function are selectively modulated by the PI3KAkt-GSK3 pathway. Immunology 132, 567-577.
-
(2011)
Immunology
, vol.132
, pp. 567-577
-
-
Antoniv, T.T.1
Ivashkiv, L.B.2
-
61
-
-
34547736572
-
Crosstalk among Jak-STAT, Toll-like receptor, and ITAM-dependent pathways in macrophage activation
-
Hu, X., Chen, J., Wang, L., Ivashkiv, L. B. (2007) Crosstalk among Jak-STAT, Toll-like receptor, and ITAM-dependent pathways in macrophage activation. J. Leukoc. Biol. 82, 237-243.
-
(2007)
J. Leukoc. Biol.
, vol.82
, pp. 237-243
-
-
Hu, X.1
Chen, J.2
Wang, L.3
Ivashkiv, L.B.4
-
62
-
-
0035337139
-
Reversing lipopolysaccharide toxicity by ligating the macrophage Fc γ receptors
-
Gerber, J. S., Mosser, D. M. (2001) Reversing lipopolysaccharide toxicity by ligating the macrophage Fc γ receptors. J. Immunol. 166, 6861-6868.
-
(2001)
J. Immunol.
, vol.166
, pp. 6861-6868
-
-
Gerber, J.S.1
Mosser, D.M.2
-
63
-
-
84855387052
-
Myeloid cell IL-10 production in response to leishmania involves inactivation of glycogen synthase kinase-3β downstream of phosphatidylinositol-3 kinase
-
Nandan, D., Camargo de Oliveira, C., Moeenrezakhanlou, A., Lopez, M., Silverman, J. M., Subek, J., Reiner, N. E. (2012) Myeloid cell IL-10 production in response to leishmania involves inactivation of glycogen synthase kinase-3β downstream of phosphatidylinositol-3 kinase. J. Immunol. 188, 367-378.
-
(2012)
J. Immunol.
, vol.188
, pp. 367-378
-
-
Nandan, D.1
de Oliveira Camargo, C.2
Moeenrezakhanlou, A.3
Lopez, M.4
Silverman, J.M.5
Subek, J.6
Reiner, N.E.7
-
64
-
-
83955165421
-
Deficiency in TLR2 but not in TLR4 impairs dendritic cells derived IL-10 responses to schistosome antigens
-
Gao, Y., Zhang, M., Chen, L., Hou, M., Ji, M., Wu, G. (2012) Deficiency in TLR2 but not in TLR4 impairs dendritic cells derived IL-10 responses to schistosome antigens. Cell. Immunol. 272, 242-250.
-
(2012)
Cell. Immunol.
, vol.272
, pp. 242-250
-
-
Gao, Y.1
Zhang, M.2
Chen, L.3
Hou, M.4
Ji, M.5
Wu, G.6
-
65
-
-
77951647275
-
Bacterial teichoic acids reverse predominant IL-12 production induced by certain lactobacillus strains into predominant IL-10 production via TLR2-dependent ERK activation in macrophages
-
Kaji, R., Kiyoshima-Shibata, J., Nagaoka, M., Nanno, M., Shida, K. (2010) Bacterial teichoic acids reverse predominant IL-12 production induced by certain lactobacillus strains into predominant IL-10 production via TLR2-dependent ERK activation in macrophages. J. Immunol. 184, 3505-3513.
-
(2010)
J. Immunol.
, vol.184
, pp. 3505-3513
-
-
Kaji, R.1
Kiyoshima-Shibata, J.2
Nagaoka, M.3
Nanno, M.4
Shida, K.5
-
66
-
-
77950535933
-
Nucleotide-binding oligomerization domain 2 and Toll-like receptor 2 function independently in a murine model of arthritis triggered by intraarticular peptidoglycan
-
Rosenzweig, H. L., Jann, M. J., Vance, E. E., Planck, S. R., Rosenbaum, J. T., Davey, M. P. (2010) Nucleotide-binding oligomerization domain 2 and Toll-like receptor 2 function independently in a murine model of arthritis triggered by intraarticular peptidoglycan. Arthritis Rheum. 62, 1051-1059.
-
(2010)
Arthritis Rheum.
, vol.62
, pp. 1051-1059
-
-
Rosenzweig, H.L.1
Jann, M.J.2
Vance, E.E.3
Planck, S.R.4
Rosenbaum, J.T.5
Davey, M.P.6
-
67
-
-
30644473611
-
TLR2 modulates inflammation in zymosan-induced arthritis in mice
-
Frasnelli, M. E., Tarussio, D., Chobaz-Peclat, V., Busso, N., So, A. (2005) TLR2 modulates inflammation in zymosan-induced arthritis in mice. Arthritis Res. Ther. 7, R370-R379.
-
(2005)
Arthritis Res. Ther.
, vol.7
-
-
Frasnelli, M.E.1
Tarussio, D.2
Chobaz-Peclat, V.3
Busso, N.4
So, A.5
-
68
-
-
80051666900
-
Dectin-1 and NOD2 mediate cathepsin activation in zymosan-induced arthritis in mice
-
Rosenzweig, H. L., Clowers, J. S., Nunez, G., Rosenbaum, J. T., Davey, M. P. (2011) Dectin-1 and NOD2 mediate cathepsin activation in zymosan-induced arthritis in mice. Inflamm. Res. 60, 705-714.
-
(2011)
Inflamm. Res.
, vol.60
, pp. 705-714
-
-
Rosenzweig, H.L.1
Clowers, J.S.2
Nunez, G.3
Rosenbaum, J.T.4
Davey, M.P.5
-
69
-
-
79951854918
-
Blockade of Toll-like receptor 2 prevents spontaneous cytokine release from rheumatoid arthritis ex vivo synovial explant cultures
-
Ultaigh, S. N., Saber, T. P., McCormick, J., Connolly, M., Dellacasagrande, J., Keogh, B., McCormack, W., Reilly, M., O'Neill, L. A., McGuirk, P., Fearon, U., Veale, D. J. (2011) Blockade of Toll-like receptor 2 prevents spontaneous cytokine release from rheumatoid arthritis ex vivo synovial explant cultures. Arthritis Res. Ther. 13, R33.
-
(2011)
Arthritis Res. Ther.
, vol.13
-
-
Ultaigh, S.N.1
Saber, T.P.2
McCormick, J.3
Connolly, M.4
Dellacasagrande, J.5
Keogh, B.6
McCormack, W.7
Reilly, M.8
O'Neill, L.A.9
McGuirk, P.10
Fearon, U.11
Veale, D.J.12
|