Bioreducible alginate-poly(ethylenimine) nanogels as an antigen-delivery system robustly enhance vaccine-elicited humoral and cellular immune responses

Journal of Controlled Release

Volumn 168, Issue 3, 2013, Pages 271-279

  Li, Ping ^a   Luo, Zichao ^a   Liu, Peng ^a   Gao, Ningning ^a   Zhang, Yijuan ^a   Pan, Hong ^a   Liu, Lanlan ^a   Wang, Ce ^a   Cai, Lintao ^a   Ma, Yifan ^a  

^a INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

Author keywords

Antibody production; Antigen presentation; Bioreducible nanogel; Cytotoxic; T lymphocyte response; Vaccine adjuvant

Indexed keywords

ANTIBODY PRODUCTION; ANTIGEN PRESENTATION; CYTOTOXIC; NANOGELS; T-LYMPHOCYTE RESPONSE; VACCINE ADJUVANTS;

ALGINATE; ANTIBODIES; ANTIGENS; CYTOTOXICITY; IMMUNE SYSTEM; LOADING; SODIUM ALGINATE; VACCINES;

NANOSTRUCTURED MATERIALS;

ADJUVANT; ALGINATE POLYETHYLENIMINE; DISULFIDE; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; IMMUNOGLOBULIN G2B; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY PRODUCTION; ANTIGEN PRESENTATION; ARTICLE; B LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL MATURATION; CELLULAR DISTRIBUTION; CELLULAR IMMUNITY; CONTROLLED STUDY; CROSS LINKING; CYTOKINE PRODUCTION; CYTOSOL; CYTOTOXICITY TEST; DENDRITIC CELL; DRUG DELIVERY SYSTEM; FEMALE; HUMORAL IMMUNITY; HYDRODYNAMICS; LYMPHOCYTE ACTIVATION; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; STATIC ELECTRICITY; TH1 CELL; ZETA POTENTIAL;

ALGINATES; ANIMALS; ANTIGEN PRESENTATION; ANTIGENS; BONE MARROW CELLS; CD8-POSITIVE T-LYMPHOCYTES; CELL LINE; CELL SURVIVAL; CELLS, CULTURED; DENDRITIC CELLS; DRUG DELIVERY SYSTEMS; FEMALE; GELS; GLUCURONIC ACID; HEXURONIC ACIDS; IMMUNOGLOBULIN G; INTERFERON-GAMMA; INTERLEUKIN-5; MICE; MICE, INBRED C57BL; OVALBUMIN; POLYETHYLENEIMINE; SPLEEN; VACCINES;

EID: 84877058701     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2013.03.025     Document Type: Article

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