Disulfide-crosslinked polyion micelles for delivery of protein therapeutics

Annals of Biomedical Engineering

Volumn 37, Issue 10, 2009, Pages 1993-2002

  Heffernan, Michael J ^a   Murthy, Niren ^a  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Catalase; CpG DNA; Drug delivery; Nanocomplex; Ovalbumin; Polylysine

Indexed keywords

CATALASE; CPG-DNA; NANOCOMPLEX; OVALBUMIN; POLYLYSINE;

ADDITION REACTIONS; AMINES; AMINO ACIDS; BLOCK COPOLYMERS; DIFFUSERS (OPTICAL); DNA; DRUG DELIVERY; ENZYMES; ETHYLENE; ETHYLENE GLYCOL; GENES; LIGANDS; MICELLES; NUCLEIC ACIDS; PHASE LOCKED LOOPS; POLYETHYLENE OXIDES; VACCINES;

POLYETHYLENE GLYCOLS;

CROSS LINKING REAGENT; DISULFIDE; DRUG CARRIER; ION; NANOMATERIAL; PROTEIN;

ARTICLE; CHEMISTRY; DRUG FORMULATION; METHODOLOGY; MICELLE; SYNTHESIS; ULTRASTRUCTURE;

CROSS-LINKING REAGENTS; DISULFIDES; DRUG CARRIERS; DRUG COMPOUNDING; IONS; MICELLES; NANOSTRUCTURES; PROTEINS;

EID: 70349213715     PISSN: 00906964     EISSN: 15739686     Source Type: Journal    
DOI: 10.1007/s10439-009-9734-x     Document Type: Article

References (32)

1. S. H. Bae Y. J. Park J. B. Park Y. S. Choi M. S. Kim J. I. Sin 2007 Therapeutic synergy of human papillomavirus E7 subunit vaccines plus cisplatin in an animal tumor model: causal involvement of increased sensitivity of cisplatin-treated tumors to CTL-mediated killing in therapeutic synergy Clin. Cancer Res. 13 341 349 17200373 10.1158/1078-0432.CCR-06-1838 1:CAS:528:DC%2BD2sXotlam (Pubitemid 46121888)
2. T. A. Burrow R. J. Hopkin N. D. Leslie B. T. Tinkle G. A. Grabowski 2007 Enzyme reconstitution/replacement therapy for lysosomal storage diseases Curr. Opin. Pediatr. 19 628 635 18025928 10.1097/MOP.0b013e3282f161f2 (Pubitemid 350145229)
3. D. J. Crommelin G. Storm R. Verrijk L. de Leede W. Jiskoot W. E. Hennink 2003 Shifting paradigms: biopharmaceuticals versus low molecular weight drugs Int. J. Pharm. 266 3 16 14559389 10.1016/S0378-5173(03)00376-4 1:CAS:528:DC%2BD3sXotVSjtbc%3D (Pubitemid 37249303)
4. B. J. Day 2004 Catalytic antioxidants: a radical approach to new therapeutics Drug Discov. Today 9 557 566 15203091 10.1016/S1359-6446(04)03139-3 1:CAS:528:DC%2BD2cXltVOhtr4%3D (Pubitemid 38760179)
5. S. Frokjaer D. E. Otzen 2005 Protein drug stability: a formulation challenge Nat. Rev. Drug Discov. 4 298 306 15803194 10.1038/nrd1695 1:CAS:528:DC%2BD2MXivVartL0%3D (Pubitemid 41130943)
6. E. Fuguet C. van Platerink H. G. Janssen 2007 Analytical characterisation of glutardialdehyde cross-linking products in gelatine-gum arabic complex coacervates Anal. Chim. Acta 604 45 53 17983779 10.1016/j.aca.2007.07.002 1:CAS:528:DC%2BD2sXht1Oru7jF (Pubitemid 350029712)
7. S. Hamdy P. Elamanchili A. Alshamsan O. Molavi T. Satou J. Samuel 2007 Enhanced antigen-specific primary CD4+ and CD8+ responses by codelivery of ovalbumin and toll-like receptor ligand monophosphoryl lipid A in poly(D,L-lactic-co-glycolic acid) nanoparticles J. Biomed. Mater. Res. A 81 652 662 17187395
8. S. Hamdy O. Molavi Z. Ma A. Haddadi A. Alshamsan Z. Gobti S. Elhasi J. Samuel A. Lavasanifar 2008 Co-delivery of cancer-associated antigen and Toll-like receptor 4 ligand in PLGA nanoparticles induces potent CD8+ T cell-mediated anti-tumor immunity Vaccine 26 5046 5057 18680779 10.1016/j.vaccine.2008.07.035 1:CAS:528:DC%2BD1cXhtVynsL7O
9. J. Hao M. Kwissa B. Pulendran N. Murthy 2006 Peptide crosslinked micelles: a new strategy for the design and synthesis of peptide vaccines Int. J. Nanomedicine 1 97 103 17722267 10.2147/nano.2006.1.1.97 1:CAS:528: DC%2BD28XhtFSjsrvK
10. A. Harada K. Kataoka 1995 Formation of polyion complex micelles in an aqueous milieu from a pair of oppositely-charged block copolymers with poly(ethylene glycol) segments Macromolecules 28 5294 5299 10.1021/ma00119a019 1:CAS:528:DyaK2MXmsFejtrY%3D
11. A. Harada K. Kataoka 1998 Novel polyion complex micelles entrapping enzyme molecules in the core: preparation of narrowly-distributed micelles from lysozyme and poly(ethylene glycol)-poly(aspartic acid) block copolymer in aqueous medium Macromolecules 31 288 294 10.1021/ma971277v 1:CAS:528: DyaK1cXit1Wgsg%3D%3D
12. A. Heit F. Schmitz T. Haas D. H. Busch H. Wagner 2007 Antigen co-encapsulated with adjuvants efficiently drive protective T cell immunity Eur. J. Immunol. 37 2063 2074 17628858 10.1002/eji.200737169 1:CAS:528: DC%2BD2sXpslCitLc%3D (Pubitemid 47250198)
13. M. L. Immordino F. Dosio L. Cattel 2006 Stealth liposomes: review of the basic science, rationale, and clinical applications, existing and potential Int. J. Nanomedicine 1 297 315 17717971 10.2217/17435889.1.3.297 1:CAS:528:DC%2BD28Xhtlantb7E
14. M. Jaturanpinyo A. Harada X. Yuan K. Kataoka 2004 Preparation of bionanoreactor based on core-shell structured polyion complex micelles entrapping trypsin in the core cross-linked with glutaraldehyde Bioconjug. Chem. 15 344 348 15025530 10.1021/bc034149m 1:CAS:528:DC%2BD2cXht12hurs%3D (Pubitemid 38365194)
15. W. Jiang R. K. Gupta M. C. Deshpande S. P. Schwendeman 2005 Biodegradable poly(lactic-co-glycolic acid) microparticles for injectable delivery of vaccine antigens Adv. Drug Deliv. Rev. 57 391 410 15560948 10.1016/j.addr.2004.09.003 1:CAS:528:DC%2BD2cXhtVSntbrO (Pubitemid 39550967)
16. Y. Kakizawa A. Harada K. Kataoka 1999 Environment-sensitive stabilization of core-shell structured polyion complex micelle by reversible cross-linking of the core through disulfide bond J. Am. Chem. Soc. 121 11247 11248 10.1021/ja993057y 1:CAS:528:DyaK1MXnsFOmtrc%3D
17. K. Kataoka A. Harada Y. Nagasaki 2001 Block copolymer micelles for drug delivery: design, characterization and biological significance Adv. Drug Deliv. Rev. 47 113 131 11251249 10.1016/S0169-409X(00)00124-1 1:CAS:528: DC%2BD3MXhvVajs78%3D (Pubitemid 32209236)
18. D. M. Klinman 2006 Adjuvant activity of CpG oligodeoxynucleotides Int. Rev. Immunol. 25 135 154 16818369 10.1080/08830180600743057 1:CAS:528: DC%2BD28XotVekt7Y%3D (Pubitemid 44034578)
19. A. M. Krieg 2002 CpG motifs in bacterial DNA and their immune effects Annu. Rev. Immunol. 20 709 760 11861616 10.1146/annurev.immunol.20.100301.064842 1:CAS:528:DC%2BD38XjtlWgtbw%3D (Pubitemid 34293438)
20. H. Maeda J. Wu T. Sawa Y. Matsumura K. Hori 2000 Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review J. Control. Release 65 271 284 10699287 10.1016/S0168-3659(99)00248-5 1:CAS:528:DC%2BD3cXhtl2qsLo%3D (Pubitemid 30122932)
21. S. Matsumoto R. J. Christie N. Nishiyama K. Miyata A. Ishii M. Oba H. Koyama Y. Yamasaki K. Kataoka 2009 Environment-responsive block copolymer micelles with a disulfide cross-linked core for enhanced siRNA delivery Biomacromolecules 10 119 127 19061333 10.1021/bm800985e 1:CAS:528: DC%2BD1cXhsVKlu7vP
22. K. Miyata Y. Kakizawa N. Nishiyama A. Harada Y. Yamasaki H. Koyama K. Kataoka 2004 Block catiomer polyplexes with regulated densities of charge and disulfide cross-linking directed to enhance gene expression J. Am. Chem. Soc. 126 2355 2361 14982439 10.1021/ja0379666 1:CAS:528:DC%2BD2cXhtVaktbs%3D (Pubitemid 38295715)
23. N. Murthy M. Xu S. Schuck J. Kunisawa N. Shastri J. M. Frechet 2003 A macromolecular delivery vehicle for protein-based vaccines: acid-degradable protein-loaded microgels Proc. Natl. Acad. Sci. USA 100 4995 5000 12704236 10.1073/pnas.0930644100 1:CAS:528:DC%2BD3sXjs1yju7g%3D (Pubitemid 36542647)
24. M. Nishikawa A. Tamada K. Hyoudou Y. Umeyama Y. Takahashi Y. Kobayashi H. Kumai E. Ishida F. Staud Y. Yabe Y. Takakura F. Yamashita M. Hashida 2004 Inhibition of experimental hepatic metastasis by targeted delivery of catalase in mice Clin. Exp. Metastasis 21 213 221 15387371 10.1023/B:CLIN.0000037706. 13747.5e 1:CAS:528:DC%2BD2cXmsFSks7k%3D (Pubitemid 39158498)
25. C. H. Niu Y. Y. Chiu 1998 FDA perspective on peptide formulation and stability issues J. Pharm. Sci. 87 1331 1334 9811485 10.1021/js9800782 1:CAS:528:DyaK1cXlvFWlu70%3D (Pubitemid 28514136)
26. H. Sah 1997 A new strategy to determine the actual protein content of poly(lactide-co-glycolide) microspheres J. Pharm. Sci. 86 1315 1318 9383747 10.1021/js960363q 1:CAS:528:DyaK2sXmsFynurY%3D (Pubitemid 27486108)
27. M. Singh J. Kazzaz M. Ugozzoli P. Malyala J. Chesko D. T. O'Hagan 2006 Polylactide-co-glycolide microparticles with surface adsorbed antigens as vaccine delivery systems Curr. Drug Deliv. 3 115 120 16472100 10.2174/156720106775197565 1:CAS:528:DC%2BD28XktlCitQ%3D%3D
28. S. M. Standley I. Mende S. L. Goh Y. J. Kwon T. T. Beaudette E. G. Engleman J. M. Frechet 2007 Incorporation of CpG oligonucleotide ligand into protein-loaded particle vaccines promotes antigen-specific CD8 T-cell immunity Bioconjug. Chem. 18 77 83 17226959 10.1021/bc060165i 1:CAS:528: DC%2BD28XhtlCgs7%2FP (Pubitemid 46145996)
29. H. Tamber P. Johansen H. P. Merkle B. Gander 2005 Formulation aspects of biodegradable polymeric microspheres for antigen delivery Adv. Drug Deliv. Rev. 57 357 376 15560946 10.1016/j.addr.2004.09.002 1:CAS:528:DC%2BD2cXhtVSntbrM (Pubitemid 39555502)
30. G. Trinchieri A. Sher 2007 Cooperation of Toll-like receptor signals in innate immune defence Nat. Rev. Immunol. 7 179 190 17318230 10.1038/nri2038 1:CAS:528:DC%2BD2sXitVGrtbc%3D (Pubitemid 46310482)
31. F. Yuan M. Dellian D. Fukumura M. Leunig D. A. Berk V. P. Torchilin R. K. Jain 1995 Vascular permeability in a human tumor xenograft: molecular size dependence and cutoff size Cancer Res. 55 3752 3756 7641188 1:CAS:528: DyaK2MXnvVelsLc%3D
32. X. Yuan A. Harada Y. Yamasaki K. Kataoka 2005 Stabilization of lysozyme-incorporated polyion complex micelles by the omega-end derivatization of poly(ethylene glycol)-poly(alpha, beta-aspartic acid) block copolymers with hydrophobic groups Langmuir 21 2668 2674 15779933 10.1021/la0488811 1:CAS:528:DC%2BD2MXht1Clsbk%3D (Pubitemid 40448925)