메뉴 건너뛰기




Volumn 1, Issue 1, 2011, Pages 1-11

Analysis and application of bacillus subtilis sortases to anchor recombinant proteins on the cell wall

Author keywords

B. subtilis; Microbiorobot; Sortase; Surface display; YhcR; YhcS

Indexed keywords

CHLORAMPHENICOL; ERYTHROMYCIN; NEOMYCIN; RECOMBINANT PROTEIN; SORTASE;

EID: 84877016500     PISSN: None     EISSN: 21910855     Source Type: Journal    
DOI: 10.1186/2191-0855-1-22     Document Type: Article
Times cited : (30)

References (46)
  • 2
    • 21844433171 scopus 로고    scopus 로고
    • Genome-wide detection and analysis of cell wall-bound proteins with LPxTG-like sorting motifs
    • doi:10.1128/JB.187.14.4928-4934.2005
    • Boekhorst J, de Been MW, Kleerebezem M, Siezen RJ (2005) Genome-wide detection and analysis of cell wall-bound proteins with LPxTG-like sorting motifs. J Bacteriol 187(14):4928-4934. doi:10.1128/JB.187.14.4928-4934.2005.
    • (2005) J Bacteriol , vol.187 , Issue.14 , pp. 4928-4934
    • Boekhorst, J.1    de Been, M.W.2    Kleerebezem, M.3    Siezen, R.J.4
  • 3
    • 0346732992 scopus 로고    scopus 로고
    • Purification and characterization of YfkN, a trifunctional nucleotide phosphoesterase secreted by Bacillus subtilis
    • Chambert R, Pereira Y, Petit-Glatron MF (2003) Purification and characterization of YfkN, a trifunctional nucleotide phosphoesterase secreted by Bacillus subtilis. J Biochem(Tokyo) 134(5):655-660.
    • (2003) J Biochem(Tokyo) , vol.134 , Issue.5 , pp. 655-660
    • Chambert, R.1    Pereira, Y.2    Petit-Glatron, M.F.3
  • 4
    • 77956286293 scopus 로고    scopus 로고
    • Sortase transpeptidases: Insights into mechanism, substrate specificity, and inhibition
    • doi:10.1002/bip.21472
    • Clancy KW, Melvin JA, McCafferty DG (2010) Sortase transpeptidases: insights into mechanism, substrate specificity, and inhibition. Biopolymers 94(4):385-396. doi:10.1002/bip.21472.
    • (2010) Biopolymers , vol.94 , Issue.4 , pp. 385-396
    • Clancy, K.W.1    Melvin, J.A.2    McCafferty, D.G.3
  • 5
    • 2142808787 scopus 로고    scopus 로고
    • A comparative genome analysis identifies distinct sorting pathways in gram-positive bacteria
    • doi:10.1128/IAI.72.5.2710-2722.2004
    • Comfort D, Clubb RT (2004) A comparative genome analysis identifies distinct sorting pathways in gram-positive bacteria. Infect Immun 72(5):2710-2722. doi:10.1128/IAI.72.5.2710-2722.2004.
    • (2004) Infect Immun , vol.72 , Issue.5 , pp. 2710-2722
    • Comfort, D.1    Clubb, R.T.2
  • 6
    • 34548814155 scopus 로고    scopus 로고
    • Protein engineering with bacterial display
    • doi:10.1016/j.sbi.2007.07.004
    • Daugherty PS (2007) Protein engineering with bacterial display. Curr Opin Struct Biol 17(4):474-480. doi:10.1016/j.sbi.2007.07.004.
    • (2007) Curr Opin Struct Biol , vol.17 , Issue.4 , pp. 474-480
    • Daugherty, P.S.1
  • 8
    • 33645049557 scopus 로고    scopus 로고
    • Protein cell surface display in Gram-positive bacteria: From single protein to macromolecular protein structure
    • doi:10.1111/j.1574-6968.2006.00122.x
    • Desvaux M, Dumas E, Chafsey I, Hebraud M (2006) Protein cell surface display in Gram-positive bacteria: from single protein to macromolecular protein structure. FEMS Microbiol Lett 256(1):1-15. doi:10.1111/j.1574-6968.2006.00122.x.
    • (2006) FEMS Microbiol Lett , vol.256 , Issue.1 , pp. 1-15
    • Desvaux, M.1    Dumas, E.2    Chafsey, I.3    Hebraud, M.4
  • 9
    • 0034603801 scopus 로고    scopus 로고
    • Anchor structure of cell wall surface proteins in Listeria monocytogenes
    • doi:10.1021/bi992347o
    • Dhar G, Faull KF, Schneewind O (2000) Anchor structure of cell wall surface proteins in Listeria monocytogenes. Biochemistry 39(13):3725-3733. doi:10.1021/bi992347o.
    • (2000) Biochemistry , vol.39 , Issue.13 , pp. 3725-3733
    • Dhar, G.1    Faull, K.F.2    Schneewind, O.3
  • 10
    • 16844372650 scopus 로고    scopus 로고
    • Sorting sortases: A nomenclature proposal for the various sortases of Gram-positive bacteria
    • doi:10.1016/j.resmic.2004.10.011
    • Dramsi S, Trieu-Cuot P, Bierne H (2005) Sorting sortases: a nomenclature proposal for the various sortases of Gram-positive bacteria. Res Microbiol 156(3):289-297. doi:10.1016/j.resmic.2004.10.011.
    • (2005) Res Microbiol , vol.156 , Issue.3 , pp. 289-297
    • Dramsi, S.1    Trieu-Cuot, P.2    Bierne, H.3
  • 11
    • 0025077034 scopus 로고
    • Conservation of a hexapeptide sequence in the anchor region of surface proteins from gram-positive cocci
    • doi:10.1111/j.1365-2958.1990.tb02072.x
    • Fischetti VA, Pancholi V, Schneewind O (1990) Conservation of a hexapeptide sequence in the anchor region of surface proteins from gram-positive cocci. Mol Microbiol 4(9):1603-1605. doi:10.1111/j.1365-2958.1990.tb02072.x.
    • (1990) Mol Microbiol , vol.4 , Issue.9 , pp. 1603-1605
    • Fischetti, V.A.1    Pancholi, V.2    Schneewind, O.3
  • 12
    • 0032989815 scopus 로고    scopus 로고
    • Post-transcriptional regulation of the Bacillus subtilis dnaK operon
    • doi:10.1046/j.1365-2958.1999.01428.x
    • Homuth G, Mogk A, Schumann W (1999) Post-transcriptional regulation of the Bacillus subtilis dnaK operon. Mol Microbiol 32(6):1183-1197. doi:10.1046/j.1365-2958.1999.01428.x.
    • (1999) Mol Microbiol , vol.32 , Issue.6 , pp. 1183-1197
    • Homuth, G.1    Mogk, A.2    Schumann, W.3
  • 13
    • 13544262411 scopus 로고    scopus 로고
    • Tetracycline-dependent conditional gene knockout in Bacillus subtilis
    • doi:10.1128/AEM.71.2.728-733.2005
    • Kamionka A, Bertram R, Hillen W (2005) Tetracycline-dependent conditional gene knockout in Bacillus subtilis. Appl Environ Microbiol 71(2):728-733. doi:10.1128/AEM.71.2.728-733.2005.
    • (2005) Appl Environ Microbiol , vol.71 , Issue.2 , pp. 728-733
    • Kamionka, A.1    Bertram, R.2    Hillen, W.3
  • 14
    • 0030605248 scopus 로고    scopus 로고
    • A xylose-inducible Bacillus subtilis integration vector and its application
    • doi:10.1016/S0378-1119(96)00466-0
    • Kim L, Mogk A, Schumann W (1996) A xylose-inducible Bacillus subtilis integration vector and its application. Gene 181(1-2):71-76. doi:10.1016/S0378-1119(96)00466-0.
    • (1996) Gene , vol.181 , Issue.1-2 , pp. 71-76
    • Kim, L.1    Mogk, A.2    Schumann, W.3
  • 15
    • 41149117526 scopus 로고    scopus 로고
    • Sortase as a target of anti-infective therapy
    • doi:10.1124/pr.107.07110
    • Maresso AW, Schneewind O (2008) Sortase as a target of anti-infective therapy. Pharmacol Rev 60(1):128-141. doi:10.1124/pr.107.07110.
    • (2008) Pharmacol Rev , vol.60 , Issue.1 , pp. 128-141
    • Maresso, A.W.1    Schneewind, O.2
  • 16
    • 33645137247 scopus 로고    scopus 로고
    • Sortases and the art of anchoring proteins to the envelopes of gram-positive bacteria
    • doi:10.1128/MMBR.70.1.192-221.2006
    • Marraffini LA, Dedent AC, Schneewind O (2006) Sortases and the art of anchoring proteins to the envelopes of gram-positive bacteria. Microbiol Mol Biol Rev 70(1):192-221. doi:10.1128/MMBR.70.1.192-221.2006.
    • (2006) Microbiol Mol Biol Rev , vol.70 , Issue.1 , pp. 192-221
    • Marraffini, L.A.1    Dedent, A.C.2    Schneewind, O.3
  • 17
    • 0033618622 scopus 로고    scopus 로고
    • Staphylococcus aureus sortase, an enzyme that anchors surface proteins to the cell wall
    • doi:10.1126/science.285.5428.760
    • Mazmanian SK, Liu G, Ton-That H, Schneewind O (1999) Staphylococcus aureus sortase, an enzyme that anchors surface proteins to the cell wall. Science 285(5428):760-763. doi:10.1126/science.285.5428.760.
    • (1999) Science , vol.285 , Issue.5428 , pp. 760-763
    • Mazmanian, S.K.1    Liu, G.2    Ton-That, H.3    Schneewind, O.4
  • 19
    • 27144523463 scopus 로고    scopus 로고
    • Construction of plasmid-based expression vectors for Bacillus subtilis exhibiting full structural stability
    • doi:10.1016/j. plasmid.2005.05.001
    • Nguyen HD, Nguyen QA, Ferreira RC, Ferreira LC, Tran LT, Schumann W (2005) Construction of plasmid-based expression vectors for Bacillus subtilis exhibiting full structural stability. Plasmid 54(3):241-248. doi:10.1016/j. plasmid.2005.05.001.
    • (2005) Plasmid , vol.54 , Issue.3 , pp. 241-248
    • Nguyen, H.D.1    Nguyen, Q.A.2    Ferreira, R.C.3    Ferreira, L.C.4    Tran, L.T.5    Schumann, W.6
  • 20
    • 34547102994 scopus 로고    scopus 로고
    • Expression vectors for the rapid purification of recombinant proteins in Bacillus subtilis
    • doi:10.1007/s00284-006-0419-5
    • Nguyen HD, Phan TTP, Schumann W (2007) Expression vectors for the rapid purification of recombinant proteins in Bacillus subtilis. Current Microbiology 55(2):89-93. doi:10.1007/s00284-006-0419-5.
    • (2007) Current Microbiology , vol.55 , Issue.2 , pp. 89-93
    • Nguyen, H.D.1    Phan, T.T.P.2    Schumann, W.3
  • 21
    • 33645333138 scopus 로고    scopus 로고
    • Establishment of an experimental system allowing immobilization of proteins on the surface of Bacillus subtilis cells
    • doi:10.1016/j.jbiotec.2005.09.012
    • Nguyen HD, Schumann W (2006) Establishment of an experimental system allowing immobilization of proteins on the surface of Bacillus subtilis cells. J Biotechnol 122:473-482. doi:10.1016/j.jbiotec.2005.09.012.
    • (2006) J Biotechnol , vol.122 , pp. 473-482
    • Nguyen, H.D.1    Schumann, W.2
  • 22
    • 3843123048 scopus 로고    scopus 로고
    • Bacillus subtilis YhcR, a highmolecular- weight, nonspecific endonuclease with a unique domain structure
    • doi:10.1128/JB.186.16.5376-5383.2004
    • Oussenko IA, Sanchez R, Bechhofer DH (2004) Bacillus subtilis YhcR, a highmolecular- weight, nonspecific endonuclease with a unique domain structure. J Bacteriol 186(16):5376-5383. doi:10.1128/JB.186.16.5376-5383.2004.
    • (2004) J Bacteriol , vol.186 , Issue.16 , pp. 5376-5383
    • Oussenko, I.A.1    Sanchez, R.2    Bechhofer, D.H.3
  • 23
    • 34248590943 scopus 로고    scopus 로고
    • Evaluation of different promoter sequences and antigen sorting signals on the immunogenicity of Bacillus subtilis vaccine vehicles
    • doi:10.1016/j.vaccine.2007.04.021
    • Paccez JD, Nguyen HD, Luiz WB, Ferreira RC, Sbrogio-Almeida ME, Schumann W, Ferreira LC (2007) Evaluation of different promoter sequences and antigen sorting signals on the immunogenicity of Bacillus subtilis vaccine vehicles. Vaccine 25(24):4671-4680. doi:10.1016/j.vaccine.2007.04.021.
    • (2007) Vaccine , vol.25 , Issue.24 , pp. 4671-4680
    • Paccez, J.D.1    Nguyen, H.D.2    Luiz, W.B.3    Ferreira, R.C.4    Sbrogio-Almeida, M.E.5    Schumann, W.6    Ferreira, L.C.7
  • 24
    • 0344889101 scopus 로고    scopus 로고
    • Bacterial resistance to ultrasonic waves under pressure at nonlethal (manosonication) and lethal (manothermosonication) temperatures
    • Pagan R, Manas P, Raso J, Condon S (1999) Bacterial resistance to ultrasonic waves under pressure at nonlethal (manosonication) and lethal (manothermosonication) temperatures. Appl Environ Microbiol 65(1):297-300
    • (1999) Appl Environ Microbiol , vol.65 , Issue.1 , pp. 297-300
    • Pagan, R.1    Manas, P.2    Raso, J.3    Condon, S.4
  • 25
    • 0035283403 scopus 로고    scopus 로고
    • An embarrassment of sortases - a richness of substrates?
    • doi:10.1016/S0966-842X(01)01956-4
    • Pallen MJ, Lam AC, Antonio M, Dunbar K (2001) An embarrassment of sortases - a richness of substrates? Trends Microbiol 9(3):97-102. doi:10.1016/S0966-842X(01)01956-4.
    • (2001) Trends Microbiol , vol.9 , Issue.3 , pp. 97-102
    • Pallen, M.J.1    Lam, A.C.2    Antonio, M.3    Dunbar, K.4
  • 26
    • 0020438726 scopus 로고
    • Molecular cloning of alpha-amylase gene from Bacillus amyloliquefaciens and its expression in B. subtilis
    • doi:10.1016/0378-1119(82)90191-3
    • Palva I (1982) Molecular cloning of alpha-amylase gene from Bacillus amyloliquefaciens and its expression in B. subtilis. Gene 19(1):81-87. doi:10.1016/0378-1119(82)90191-3.
    • (1982) Gene , vol.19 , Issue.1 , pp. 81-87
    • Palva, I.1
  • 27
    • 0842281609 scopus 로고    scopus 로고
    • The biology of Gram-positive sortase enzymes
    • doi:10.1016/j.tim.2003.12.007
    • Paterson GK, Mitchell TJ (2004) The biology of Gram-positive sortase enzymes. Trends Microbiol 12(2):89-95. doi:10.1016/j.tim.2003.12.007.
    • (2004) Trends Microbiol , vol.12 , Issue.2 , pp. 89-95
    • Paterson, G.K.1    Mitchell, T.J.2
  • 28
    • 77949487622 scopus 로고    scopus 로고
    • Establishment of a simple and rapid method to screen for strong promoters in Bacillus subtilis
    • doi:10.1016/j.pep.2009.11.010
    • Phan TT, Nguyen HD, Schumann W (2010) Establishment of a simple and rapid method to screen for strong promoters in Bacillus subtilis. Protein Expr Purif 71(2):174-178. doi:10.1016/j.pep.2009.11.010.
    • (2010) Protein Expr Purif , vol.71 , Issue.2 , pp. 174-178
    • Phan, T.T.1    Nguyen, H.D.2    Schumann, W.3
  • 29
    • 33846389252 scopus 로고    scopus 로고
    • Development of a glycine-inducible expression system for Bacillus subtilis
    • doi:10.1016/j.jbiotec.2006.12.007
    • Phan TT, Schumann W (2007) Development of a glycine-inducible expression system for Bacillus subtilis. J Biotechnol 128(3):486-499. doi:10.1016/j.jbiotec.2006.12.007.
    • (2007) J Biotechnol , vol.128 , Issue.3 , pp. 486-499
    • Phan, T.T.1    Schumann, W.2
  • 30
    • 69949184402 scopus 로고    scopus 로고
    • Transcriptional analysis of the lysine-responsive and riboswitch-regulated lysC gene of Bacillus subtilis
    • doi:10.1007/s00284-009-9461-4
    • Phan TT, Schumann W (2009) Transcriptional analysis of the lysine-responsive and riboswitch-regulated lysC gene of Bacillus subtilis. Curr Microbiol 59(4):463-468. doi:10.1007/s00284-009-9461-4.
    • (2009) Curr Microbiol , vol.59 , Issue.4 , pp. 463-468
    • Phan, T.T.1    Schumann, W.2
  • 31
    • 33645414326 scopus 로고    scopus 로고
    • Novel plasmid-based expression vectors for intra- and extracellular production of recombinant proteins in Bacillus subtilis
    • doi:10.1016/j.pep.2005.07.005
    • Phan TTP, Nguyen HD, Schumann W (2006) Novel plasmid-based expression vectors for intra- and extracellular production of recombinant proteins in Bacillus subtilis. Protein Expr Purif 46:189-195. doi:10.1016/j.pep.2005.07.005.
    • (2006) Protein Expr Purif , vol.46 , pp. 189-195
    • Phan, T.T.P.1    Nguyen, H.D.2    Schumann, W.3
  • 32
    • 77956107104 scopus 로고    scopus 로고
    • Heterologous protein secretion by Bacillus species: From the cradle to the grave
    • Pohl S, Harwood CR (2010) Heterologous protein secretion by Bacillus species: From the cradle to the grave. Adv Appl Microbiol 73:1-25
    • (2010) Adv Appl Microbiol , vol.73 , pp. 1-25
    • Pohl, S.1    Harwood, C.R.2
  • 33
    • 13944268797 scopus 로고    scopus 로고
    • A novel method for accurate operon predictions in all sequenced prokaryotes
    • doi:10.1093/nar/gki232
    • Price MN, Huang KH, Alm EJ, Arkin AP (2005) A novel method for accurate operon predictions in all sequenced prokaryotes. Nucleic Acids Res 33(3):880-892. doi:10.1093/nar/gki232.
    • (2005) Nucleic Acids Res , vol.33 , Issue.3 , pp. 880-892
    • Price, M.N.1    Huang, K.H.2    Alm, E.J.3    Arkin, A.P.4
  • 35
    • 0018289188 scopus 로고    scopus 로고
    • DIG Application Manual for Filter Hybridization, 1-209 Saito H, Shibata T, Ando T (1979) Mapping of genes determining nonpermissiveness and host-specific restriction to bacteriophages in Bacillus subtilis Marburg
    • doi:10.1007/BF00337785
    • Roche company (2003) DIG Application Manual for Filter Hybridization, 1-209 Saito H, Shibata T, Ando T (1979) Mapping of genes determining nonpermissiveness and host-specific restriction to bacteriophages in Bacillus subtilis Marburg. Mol Gen Genet 170(2):117-122. doi:10.1007/BF00337785.
    • (2003) Mol Gen Genet , vol.170 , Issue.2 , pp. 117-122
    • Company, R.1
  • 36
    • 0037178208 scopus 로고    scopus 로고
    • Display of proteins on bacteria
    • doi:10.1016/S0168-1656(02)00043-3
    • Samuelson P, Gunneriusson E, Nygren PA, Stahl S (2002) Display of proteins on bacteria. J Biotechnol 96(2):129-154. doi:10.1016/S0168-1656(02)00043-3.
    • (2002) J Biotechnol , vol.96 , Issue.2 , pp. 129-154
    • Samuelson, P.1    Gunneriusson, E.2    Nygren, P.A.3    Stahl, S.4
  • 37
    • 34548508428 scopus 로고    scopus 로고
    • Production of recombinant proteins in Bacillus subtilis
    • Schumann W (2007) Production of recombinant proteins in Bacillus subtilis. Adv Appl Microbiol 62:137-189
    • (2007) Adv Appl Microbiol , vol.62 , pp. 137-189
    • Schumann, W.1
  • 38
    • 0033818171 scopus 로고    scopus 로고
    • Signal eptidedependent protein transport in Bacillus subtilis: A genome-based survey of the secretome
    • doi:10.1128/MMBR.64.3.515-547.2000
    • Tjalsma H, Bolhuis A, Jongbloed JD, Bron S, van Dijl JM (2000) Signal eptidedependent protein transport in Bacillus subtilis: a genome-based survey of the secretome. Microbiol Mol Biol Rev 64(3):515-547. doi:10.1128/MMBR.64.3.515-547.2000.
    • (2000) Microbiol Mol Biol Rev , vol.64 , Issue.3 , pp. 515-547
    • Tjalsma, H.1    Bolhuis, A.2    Jongbloed, J.D.3    Bron, S.4    van Dijl, J.M.5
  • 39
    • 0033607265 scopus 로고    scopus 로고
    • Purification and characterization of sortase, the transpeptidase that cleaves surface proteins of Staphylococcus aureus at the LPXTG motif
    • doi:10.1073/pnas.96.22.12424
    • Ton-That H, Liu G, Mazmanian SK, Faull KF, Schneewind O (1999) Purification and characterization of sortase, the transpeptidase that cleaves surface proteins of Staphylococcus aureus at the LPXTG motif. Proc Natl Acad Sci USA 96(22):12424-12429. doi:10.1073/pnas.96.22.12424.
    • (1999) Proc Natl Acad Sci USA , vol.96 , Issue.22 , pp. 12424-12429
    • Ton-That, H.1    Liu, G.2    Mazmanian, S.K.3    Faull, K.F.4    Schneewind, O.5
  • 40
    • 8844240627 scopus 로고    scopus 로고
    • Protein sorting to the cell wall envelope of Gram-positive bacteria
    • doi:10.1016/j.bbamcr.2004.04.014
    • Ton-That H, Marraffini LA, Schneewind O (2004) Protein sorting to the cell wall envelope of Gram-positive bacteria. Biochim Biophys Acta 1694(1-3):269-278. doi:10.1016/j.bbamcr.2004.04.014.
    • (2004) Biochim Biophys Acta , vol.1694 , Issue.1-3 , pp. 269-278
    • Ton-That, H.1    Marraffini, L.A.2    Schneewind, O.3
  • 41
    • 65549164210 scopus 로고    scopus 로고
    • Sortase-mediated ligation: A gift from Gram-positive bacteria to protein engineering
    • doi:10.1002/cbic.200800724
    • Tsukiji S, Nagamune T (2009) Sortase-mediated ligation: a gift from Gram-positive bacteria to protein engineering. Chembiochem 10(5):787-798. doi:10.1002/cbic.200800724.
    • (2009) Chembiochem , vol.10 , Issue.5 , pp. 787-798
    • Tsukiji, S.1    Nagamune, T.2
  • 42
    • 0031737309 scopus 로고    scopus 로고
    • A vector for systematic gene inactivation in Bacillus subtilis
    • doi:10.1099/00221287-144-11-3097
    • Vagner V, Dervyn E, Ehrlich SD (1998) A vector for systematic gene inactivation in Bacillus subtilis. Microbiology 144:3097-3104. doi:10.1099/00221287-144-11-3097.
    • (1998) Microbiology , vol.144 , pp. 3097-3104
    • Vagner, V.1    Dervyn, E.2    Ehrlich, S.D.3
  • 43
    • 10444241949 scopus 로고    scopus 로고
    • Biotechnological applications for surface-engineered bacteria
    • Wernerus H, Stahl S (2004) Biotechnological applications for surface-engineered bacteria. Biotechnol Appl Biochem 40(Pt 3):209-228
    • (2004) Biotechnol Appl Biochem , vol.40 , Issue.Pt 3 , pp. 209-228
    • Wernerus, H.1    Stahl, S.2
  • 45
    • 0036307716 scopus 로고    scopus 로고
    • Functional production and characterization of a fibrin-specific single-chain antibody fragment from Bacillus subtilis: Effects of molecular chaperones and a wallbound protease on antibody fragment production
    • doi:10.1128/AEM.68.7.3261-3269.2002
    • Wu SC, Yeung JC, Duan Y, Ye R, Szarka SJ, Habibi HR, Wong SL (2002) Functional production and characterization of a fibrin-specific single-chain antibody fragment from Bacillus subtilis: effects of molecular chaperones and a wallbound protease on antibody fragment production. Appl Environ Microbiol 68(7):3261-3269. doi:10.1128/AEM.68.7.3261-3269.2002.
    • (2002) Appl Environ Microbiol , vol.68 , Issue.7 , pp. 3261-3269
    • Wu, S.C.1    Yeung, J.C.2    Duan, Y.3    Ye, R.4    Szarka, S.J.5    Habibi, H.R.6    Wong, S.L.7
  • 46
    • 44049087994 scopus 로고    scopus 로고
    • Establishment and characterization of conditions required for tumor colonization by intravenously delivered bacteria
    • doi:10.1002/bit.21785
    • Yu YA, Zhang Q, Szalay AA (2008) Establishment and characterization of conditions required for tumor colonization by intravenously delivered bacteria. Biotechnol Bioeng 100(3):567-578. doi:10.1002/bit.21785.
    • (2008) Biotechnol Bioeng , vol.100 , Issue.3 , pp. 567-578
    • Yu, Y.A.1    Zhang, Q.2    Szalay, A.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.