메뉴 건너뛰기




Volumn 36, Issue 4, 2013, Pages 515-521

Effects of astragaloside IV on action potentials and ionic currents in guinea-pig ventricular myocytes

Author keywords

Action potential; Astragaloside IV; Cardiac myocyte; Ion channel; Patch clamp

Indexed keywords

ASTRAGALOSIDE IV; CALCIUM CHANNEL L TYPE; CALCIUM ION; DELAYED RECTIFIER POTASSIUM CHANNEL; INWARDLY RECTIFYING POTASSIUM CHANNEL; POTASSIUM ION; SODIUM ION; VOLTAGE GATED CALCIUM CHANNEL; VOLTAGE GATED SODIUM CHANNEL;

EID: 84876922576     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.b12-00655     Document Type: Article
Times cited : (27)

References (39)
  • 1
    • 69949138137 scopus 로고    scopus 로고
    • Saponin fraction from Astragalus membranaceus roots protects mice against polymicrobial sepsis induced by cecal ligation and puncture by inhibiting inflammation and upregulating protein C pathway
    • Gao XH, Xu XX, Pan R, Li Y, Luo YB, Xia YF, Murata K, Matsuda H, Dai Y. Saponin fraction from Astragalus membranaceus roots protects mice against polymicrobial sepsis induced by cecal ligation and puncture by inhibiting inflammation and upregulating protein C pathway. J. Nat. Med., 63, 421-429 (2009).
    • (2009) J. Nat. Med. , vol.63 , pp. 421-429
    • Gao, X.H.1    Xu, X.X.2    Pan, R.3    Li, Y.4    Luo, Y.B.5    Xia, Y.F.6    Murata, K.7    Matsuda, H.8    Dai, Y.9
  • 2
    • 37249028093 scopus 로고    scopus 로고
    • Astragali Radix elicits anti-inflammation via activation of MKP-1, concomitant with attenuation of p38 and Erk
    • Ryu M, Kim EH, Chun M, Kang S, Shim B, Yu YB, Jeong G, Lee JS. Astragali Radix elicits anti-inflammation via activation of MKP-1, concomitant with attenuation of p38 and Erk. J. Ethnopharmacol., 115, 184-193 (2008).
    • (2008) J. Ethnopharmacol. , vol.115 , pp. 184-193
    • Ryu, M.1    Kim, E.H.2    Chun, M.3    Kang, S.4    Shim, B.5    Yu, Y.B.6    Jeong, G.7    Lee, J.S.8
  • 3
    • 84862823621 scopus 로고    scopus 로고
    • Synergistic protective effect of astragaloside IV-tetramethylpyrazine against cerebral ischemic-reperfusion injury induced by transient focal ischemia
    • Yang J, Li J, Lu J, Zhang Y, Zhu Z, Wan H. Synergistic protective effect of astragaloside IV-tetramethylpyrazine against cerebral ischemic-reperfusion injury induced by transient focal ischemia. J. Ethnopharmacol., 140, 64-72 (2012).
    • (2012) J. Ethnopharmacol. , vol.140 , pp. 64-72
    • Yang, J.1    Li, J.2    Lu, J.3    Zhang, Y.4    Zhu, Z.5    Wan, H.6
  • 4
    • 77950899039 scopus 로고    scopus 로고
    • Astragaloside IV improves homocysteine-induced acute phase endothelial dysfunction via antioxidation
    • Qiu LH, Xie XJ, Zhang BQ. Astragaloside IV improves homocysteine-induced acute phase endothelial dysfunction via antioxidation. Biol. Pharm. Bull., 33, 641-646 (2010).
    • (2010) Biol. Pharm. Bull. , vol.33 , pp. 641-646
    • Qiu, L.H.1    Xie, X.J.2    Zhang, B.Q.3
  • 5
    • 33846451021 scopus 로고    scopus 로고
    • Effects of Astragalus membranaceus and its main components on the acute phase endothelial dysfunction induced by homocysteine
    • Zhang BQ, Hu SJ, Qiu LH, Zhu JH, Xie XJ, Sun J, Zhu ZH, Xia Q, Bian K. Effects of Astragalus membranaceus and its main components on the acute phase endothelial dysfunction induced by homocysteine. Vascul. Pharmacol., 46, 278-285 (2007).
    • (2007) Vascul. Pharmacol. , vol.46 , pp. 278-285
    • Zhang, B.Q.1    Hu, S.J.2    Qiu, L.H.3    Zhu, J.H.4    Xie, X.J.5    Sun, J.6    Zhu, Z.H.7    Xia, Q.8    Bian, K.9
  • 7
    • 0025393796 scopus 로고
    • Effect of Astragalus membranaceus on electric activities of cultured rat beating heart cells infected with Coxsackie B-2 virus
    • Yuan WL, Chen HZ, Yang YZ, Yang XY, Lin YS, Jin PY, Zhou TS. Effect of Astragalus membranaceus on electric activities of cultured rat beating heart cells infected with Coxsackie B-2 virus. Chin. Med. J. (Engl.), 103, 177-182 (1990).
    • (1990) Chin. Med. J. (Engl.) , vol.103 , pp. 177-182
    • Yuan, W.L.1    Chen, H.Z.2    Yang, Y.Z.3    Yang, X.Y.4    Lin, Y.S.5    Jin, P.Y.6    Zhou, T.S.7
  • 8
    • 79954572848 scopus 로고    scopus 로고
    • Astragaloside IV inhibits adenovirus replication and apoptosis in A549 cells in vitro
    • Shang L, Qu Z, Sun L, Wang Y, Liu F, Wang S, Gao H, Jiang F. Astragaloside IV inhibits adenovirus replication and apoptosis in A549 cells in vitro. J. Pharm. Pharmacol., 63, 688-694 (2011).
    • (2011) J. Pharm. Pharmacol. , vol.63 , pp. 688-694
    • Shang, L.1    Qu, Z.2    Sun, L.3    Wang, Y.4    Liu, F.5    Wang, S.6    Gao, H.7    Jiang, F.8
  • 9
    • 63749091889 scopus 로고    scopus 로고
    • Astragalus extract inhibits destruction of gastric cancer cells to mesothelial cells by antiapoptosis
    • Na D, Liu FN, Miao ZF, Du ZM, Xu HM. Astragalus extract inhibits destruction of gastric cancer cells to mesothelial cells by antiapoptosis. World J. Gastroenterol., 15, 570-577 (2009).
    • (2009) World J. Gastroenterol. , vol.15 , pp. 570-577
    • Na, D.1    Liu, F.N.2    Miao, Z.F.3    Du, Z.M.4    Xu, H.M.5
  • 10
    • 79951931336 scopus 로고    scopus 로고
    • Diabetes is an inflammatory disease: evidence from traditional Chinese medicines
    • Xie W, Du L. Diabetes is an inflammatory disease: evidence from traditional Chinese medicines. Diabetes Obes. Metab., 13, 289-301 (2011).
    • (2011) Diabetes Obes. Metab. , vol.13 , pp. 289-301
    • Xie, W.1    Du, L.2
  • 11
    • 75849132824 scopus 로고    scopus 로고
    • Effect of astragaloside IV on hepatic glucose-regulating enzymes in diabetic mice induced by a high-fat diet and streptozotocin
    • Lv L, Wu SY, Wang GF, Zhang JJ, Pang JX, Liu ZQ, Xu W, Wu SG, Rao JJ. Effect of astragaloside IV on hepatic glucose-regulating enzymes in diabetic mice induced by a high-fat diet and streptozotocin. Phytother. Res., 24, 219-224 (2010).
    • (2010) Phytother. Res. , vol.24 , pp. 219-224
    • Lv, L.1    Wu, S.Y.2    Wang, G.F.3    Zhang, J.J.4    Pang, J.X.5    Liu, Z.Q.6    Xu, W.7    Wu, S.G.8    Rao, J.J.9
  • 12
    • 31644436467 scopus 로고    scopus 로고
    • Effects of astragaloside IV on pathogenesis of metabolic syndrome in vitro
    • Xu ME, Xiao SZ, Sun YH, Ou-Yang Y, Zheng XX. Effects of astragaloside IV on pathogenesis of metabolic syndrome in vitro. Acta Pharmacol. Sin., 27, 229-236 (2006).
    • (2006) Acta Pharmacol. Sin. , vol.27 , pp. 229-236
    • Xu, M.E.1    Xiao, S.Z.2    Sun, Y.H.3    Ou-Yang, Y.4    Zheng, X.X.5
  • 14
    • 22844435412 scopus 로고    scopus 로고
    • Gastroprotective effect of Astragaloside IV: role of prostaglandins, sulfhydryls and nitric oxide
    • Navarrete A, Arrieta J, Terrones L, Abou-Gazar H, Calis I. Gastroprotective effect of Astragaloside IV: role of prostaglandins, sulfhydryls and nitric oxide. J. Pharm. Pharmacol., 57, 1059-1064 (2005).
    • (2005) J. Pharm. Pharmacol. , vol.57 , pp. 1059-1064
    • Navarrete, A.1    Arrieta, J.2    Terrones, L.3    Abou-Gazar, H.4    Calis, I.5
  • 15
    • 79952486447 scopus 로고    scopus 로고
    • Effects of astragaloside IV on IFN-gamma level and prolonged airway dysfunction in a murine model of chronic asthma
    • Yuan X, Sun S, Wang S, Sun Y. Effects of astragaloside IV on IFN-gamma level and prolonged airway dysfunction in a murine model of chronic asthma. Planta Med., 77, 328-333 (2011).
    • (2011) Planta Med. , vol.77 , pp. 328-333
    • Yuan, X.1    Sun, S.2    Wang, S.3    Sun, Y.4
  • 16
    • 69249091777 scopus 로고    scopus 로고
    • Astragaloside IV increases MMP-2 mRNA and protein expression in human lung cancer A549 cells
    • Su CC, Chiou TL, Chan MH, Lin JG. Astragaloside IV increases MMP-2 mRNA and protein expression in human lung cancer A549 cells. Mol. Med. Report., 2, 107-113 (2009).
    • (2009) Mol. Med. Report. , vol.2 , pp. 107-113
    • Su, C.C.1    Chiou, T.L.2    Chan, M.H.3    Lin, J.G.4
  • 18
    • 34250835018 scopus 로고    scopus 로고
    • Modification of alterations in cardiac function and sarcoplasmic reticulum by astragaloside IV in myocardial injury in vivo
    • Xu XL, Ji H, Gu SY, Shao Q, Huang QJ, Cheng YP. Modification of alterations in cardiac function and sarcoplasmic reticulum by astragaloside IV in myocardial injury in vivo. Eur. J. Pharmacol., 568, 203-212 (2007).
    • (2007) Eur. J. Pharmacol. , vol.568 , pp. 203-212
    • Xu, X.L.1    Ji, H.2    Gu, S.Y.3    Shao, Q.4    Huang, Q.J.5    Cheng, Y.P.6
  • 21
    • 34547855812 scopus 로고    scopus 로고
    • Verrucotoxin, a stonefish venom, modulates calcium channel activity in guinea-pig ventricular myocytes
    • Yazawa K, Wang JW, Hao LY, Onoue Y, Kameyama M. Verrucotoxin, a stonefish venom, modulates calcium channel activity in guinea-pig ventricular myocytes. Br. J. Pharmacol., 151, 1198-1203 (2007).
    • (2007) Br. J. Pharmacol. , vol.151 , pp. 1198-1203
    • Yazawa, K.1    Wang, J.W.2    Hao, L.Y.3    Onoue, Y.4    Kameyama, M.5
  • 22
    • 84856285216 scopus 로고    scopus 로고
    • Astragaloside IV and cycloastragenol stimulate the phosphorylation of extracellular signal-regulated protein kinase in multiple cell types
    • Yung LY, Lam WS, Ho MK, Hu Y, Ip FC, Pang H, Chin AC, Harley CB, Ip NY, Wong YH. Astragaloside IV and cycloastragenol stimulate the phosphorylation of extracellular signal-regulated protein kinase in multiple cell types. Planta Med., 78, 115-121 (2012).
    • (2012) Planta Med. , vol.78 , pp. 115-121
    • Yung, L.Y.1    Lam, W.S.2    Ho, M.K.3    Hu, Y.4    Ip, F.C.5    Pang, H.6    Chin, A.C.7    Harley, C.B.8    Ip, N.Y.9    Wong, Y.H.10
  • 23
    • 79953780961 scopus 로고    scopus 로고
    • Astragaloside IV attenuates myocardial fibrosis by inhibiting TGF-β1 signaling in coxsackievirus B3-induced cardiomyopathy
    • Chen P, Xie Y, Shen E, Li GG, Yu Y, Zhang CB, Yang Y, Zou Y, Ge J, Chen R, Chen H. Astragaloside IV attenuates myocardial fibrosis by inhibiting TGF-β1 signaling in coxsackievirus B3-induced cardiomyopathy. Eur. J. Pharmacol., 658, 168-174 (2011).
    • (2011) Eur. J. Pharmacol. , vol.658 , pp. 168-174
    • Chen, P.1    Xie, Y.2    Shen, E.3    Li, G.G.4    Yu, Y.5    Zhang, C.B.6    Yang, Y.7    Zou, Y.8    Ge, J.9    Chen, R.10    Chen, H.11
  • 25
    • 68849105275 scopus 로고    scopus 로고
    • Astragaloside IV attenuates hypoxia-induced cardiomyocyte damage in rats by upregulating superoxide dismutase-1 levels
    • Hu JY, Han J, Chu ZG, Song HP, Zhang DX, Zhang Q, Huang YS. Astragaloside IV attenuates hypoxia-induced cardiomyocyte damage in rats by upregulating superoxide dismutase-1 levels. Clin. Exp. Pharmacol. Physiol., 36, 351-357 (2009).
    • (2009) Clin. Exp. Pharmacol. Physiol. , vol.36 , pp. 351-357
    • Hu, J.Y.1    Han, J.2    Chu, Z.G.3    Song, H.P.4    Zhang, D.X.5    Zhang, Q.6    Huang, Y.S.7
  • 26
    • 32644451004 scopus 로고    scopus 로고
    • Astragaloside IV from Astragalus membranaceus shows cardioprotection during myocardial ischemia in vivo and in vitro
    • Zhang WD, Chen H, Zhang C, Liu RH, Li HL, Chen HZ. Astragaloside IV from Astragalus membranaceus shows cardioprotection during myocardial ischemia in vivo and in vitro. Planta Med., 72, 4-8 (2006).
    • (2006) Planta Med. , vol.72 , pp. 4-8
    • Zhang, W.D.1    Chen, H.2    Zhang, C.3    Liu, R.H.4    Li, H.L.5    Chen, H.Z.6
  • 27
    • 43449089788 scopus 로고    scopus 로고
    • Astragaloside IV improved intracellular calcium handling in hypoxia-reoxygenated cardiomyocytes via the sarcoplasmic reticulum Ca-ATPase
    • Xu XL, Chen XJ, Ji H, Li P, Bian YY, Yang D, Xu JD, Bian ZP, Zhang JN. Astragaloside IV improved intracellular calcium handling in hypoxia-reoxygenated cardiomyocytes via the sarcoplasmic reticulum Ca-ATPase. Pharmacology, 81, 325-332 (2008).
    • (2008) Pharmacology , vol.81 , pp. 325-332
    • Xu, X.L.1    Chen, X.J.2    Ji, H.3    Li, P.4    Bian, Y.Y.5    Yang, D.6    Xu, J.D.7    Bian, Z.P.8    Zhang, J.N.9
  • 28
    • 0036792689 scopus 로고    scopus 로고
    • Effects of astragaloside IV on myocardial calcium transport and cardiac function in ischemic rats
    • Li ZP, Cao Q. Effects of astragaloside IV on myocardial calcium transport and cardiac function in ischemic rats. Acta Pharmacol. Sin., 23, 898-904 (2002).
    • (2002) Acta Pharmacol. Sin. , vol.23 , pp. 898-904
    • Li, Z.P.1    Cao, Q.2
  • 29
    • 0029002969 scopus 로고
    • A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel
    • Sanguinetti MC, Jiang C, Curran ME, Keating MT. A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel. Cell, 81, 299-307 (1995).
    • (1995) Cell , vol.81 , pp. 299-307
    • Sanguinetti, M.C.1    Jiang, C.2    Curran, M.E.3    Keating, M.T.4
  • 30
    • 0029952101 scopus 로고    scopus 로고
    • K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current
    • Barhanin J, Lesage F, Guillemare E, Fink M, Lazdunski M, Romey GK. K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current. Nature, 384, 78-80 (1996).
    • (1996) Nature , vol.384 , pp. 78-80
    • Barhanin, J.1    Lesage, F.2    Guillemare, E.3    Fink, M.4    Lazdunski, M.5    Romey, G.K.6
  • 31
    • 33645317063 scopus 로고    scopus 로고
    • hERG potassium channels and cardiac arrhythmia
    • Sanguinetti MC, Tristani-Firouzi M. hERG potassium channels and cardiac arrhythmia. Nature, 440, 463-469 (2006).
    • (2006) Nature , vol.440 , pp. 463-469
    • Sanguinetti, M.C.1    Tristani-Firouzi, M.2
  • 32
    • 8844228183 scopus 로고    scopus 로고
    • Effect of the antifibrillatory compound tedisamil (KC-8857) on transmembrane currents in mammalian ventricular myocytes
    • Jost N, Virág L, Hála O, Varró A, Thormählen D, Papp JG. Effect of the antifibrillatory compound tedisamil (KC-8857) on transmembrane currents in mammalian ventricular myocytes. Curr. Med. Chem., 11, 3219-3228 (2004).
    • (2004) Curr. Med. Chem. , vol.11 , pp. 3219-3228
    • Jost, N.1    Virág, L.2    Hála, O.3    Varró, A.4    Thormählen, D.5    Papp, J.G.6
  • 33
    • 84886723104 scopus 로고    scopus 로고
    • Effects of astragaloside IV, ginsenoside and total saponins of quinquefolium on mice with arrhythmia caused by toad venom
    • Lu WJ, Zhou J, Ma HY, Lv GH, You FQ, Ding AW. Effects of astragaloside IV, ginsenoside and total saponins of quinquefolium on mice with arrhythmia caused by toad venom. J. Nanjing Univ. Tradit. Chin. Med., 28, 61-64 (2012).
    • (2012) J. Nanjing Univ. Tradit. Chin. Med. , vol.28 , pp. 61-64
    • Lu, W.J.1    Zhou, J.2    Ma, H.Y.3    Lv, G.H.4    You, F.Q.5    Ding, A.W.6
  • 36
    • 0033823284 scopus 로고    scopus 로고
    • Antiarrhythmic drugs: from mechanisms to clinical practice
    • Roden DM. Antiarrhythmic drugs: from mechanisms to clinical practice. Heart, 84, 339-346 (2000).
    • (2000) Heart , vol.84 , pp. 339-346
    • Roden, D.M.1
  • 38
  • 39
    • 80053999731 scopus 로고    scopus 로고
    • Endocrine disruption via estrogen receptors that participate in nongenomic signaling pathways
    • Watson CS, Jeng YJ, Guptarak J. Endocrine disruption via estrogen receptors that participate in nongenomic signaling pathways. J. Steroid Biochem. Mol. Biol., 127, 44-50 (2011).
    • (2011) J. Steroid Biochem. Mol. Biol. , vol.127 , pp. 44-50
    • Watson, C.S.1    Jeng, Y.J.2    Guptarak, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.