Synergistic protective effect of astragaloside IV-tetramethylpyrazine against cerebral ischemic-reperfusion injury induced by transient focal ischemia

Journal of Ethnopharmacology

Volumn 140, Issue 1, 2012, Pages 64-72

  Yang, Jiehong ^a   Li, Jinhui ^b   Lu, Jing ^c   Zhang, Yuyan ^a   Zhu, Zhenhong ^a   Wan, Haitong ^a  

^a ZHEJIANG CHINESE MEDICAL UNIVERSITY   (China)

^b THE SECOND AFFILIATED HOSPITAL OF ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Apoptosis; Astragaloside IV; Ischemia reperfusion; Oxidative stress; Positron emission tomography; Tetramethylpyrazine

Indexed keywords

ASTRAGALOSIDE IV; CASPASE 3; FLUORODEOXYGLUCOSE F 18; INDUCIBLE NITRIC OXIDE SYNTHASE; MALONALDEHYDE; MESSENGER RNA; NIMODIPINE; PROTEIN BCL 2; SUPEROXIDE DISMUTASE; TETRAMETHYLPYRAZINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG POTENTIATION; ENZYME ACTIVITY; GLUCOSE METABOLISM; HIPPOCAMPUS; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROLOGIC EXAMINATION; NEUROPROTECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; POSITRON EMISSION TOMOGRAPHY; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; UPREGULATION;

ANIMALS; ASTRAGALUS PLANT; CARDIOVASCULAR AGENTS; CASPASE 3; DISEASE MODELS, ANIMAL; DRUG SYNERGISM; GLUCOSE; HIPPOCAMPUS; ISCHEMIC ATTACK, TRANSIENT; MALE; MALONDIALDEHYDE; NEUROPROTECTIVE AGENTS; NIMODIPINE; NITRIC OXIDE SYNTHASE TYPE II; PHYTOTHERAPY; PLANT EXTRACTS; POSITRON-EMISSION TOMOGRAPHY; PROTO-ONCOGENE PROTEINS C-BCL-2; PYRAZINES; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; RNA, MESSENGER; SAPONINS; SUPEROXIDE DISMUTASE; TRITERPENES;

RATTUS;

EID: 84862823621     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2011.12.023     Document Type: Article

References (38)

1. P.A. Balch Prescription for Nutritional Healing 4th ed. 2006 Avery New York
2. J.B. Bederson, L.H. Pitts, S.M. Germano, M.C. Nishimura, R.L. Davis, and H.M. Bartkowski Evaluation of 2,3,5-triphenyltetrazolium chloride as a stain for detection and quantification of experimental cerebral infarction in rats Stroke 17 1986 1304 1308 (Pubitemid 17008976)
3. L. Belayev, O.F. Alonso, R. Busto, W. Zhao, and M.D. Ginsberg Middle cerebral artery occlusion in the rat by intraluminal suture. Neurological and pathological evaluation of an improved model Stroke 27 1996 1616 1622 discussion 1623
4. Y. Chang, G. Hsiao, S.H. Chen, Y.C. Chen, J.H. Lin, K.H. Lin, D.S. Chou, and J.R. Sheu Tetramethylpyrazine suppresses HIF-1alpha, TNF-alpha, and activated caspase-3 expression in middle cerebral artery occlusion-induced brain ischemia in rats Acta Pharmacologica Sinica 28 2007 327 333
5. S.R. Cherry, and S.S. Gambhir Use of positron emission tomography in animal research ILAR Journal 42 2001 219 232 (Pubitemid 33708710)
6. H.T. Chugani, D.A. Hovda, J.R. Villablanca, M.E. Phelps, and W.F. Xu Metabolic maturation of the brain: a study of local cerebral glucose utilization in the developing cat Journal of Cerebral Blood Flow and Metabolism 11 1991 35 47
7. G.H. Danton, and W.D. Dietrich Inflammatory mechanisms after ischemia and stroke Journal of Neuropathology and Experimental Neurology 62 2003 127 136 (Pubitemid 36176947)
8. F. Gao, S. Wang, Y. Guo, J. Wang, M. Lou, J. Wu, M. Ding, M. Tian, and H. Zhang Protective effects of repetitive transcranial magnetic stimulation in a rat model of transient cerebral ischaemia: a microPET study European Journal of Nuclear Medicine and Molecular Imaging 37 2010 954 961
9. J.H. Garcia, S. Wagner, K.F. Liu, and X.J. Hu Neurological deficit and extent of neuronal necrosis attributable to middle cerebral artery occlusion in rats. Statistical validation Stroke 26 1995 627 634 discussion 635
10. M.D. Ginsberg Role of free radical reactions in ischemic brain injury Drug News & Perspectives 14 2001 81 88 (Pubitemid 32435831)
11. J.M. Gutteridge Lipid peroxidation and antioxidants as biomarkers of tissue damage Clinical Chemistry 41 1995 1819 1828
12. B.H. Han, D. Xu, J. Choi, Y. Han, S. Xanthoudakis, S. Roy, J. Tam, J. Vaillancourt, J. Colucci, R. Siman, A. Giroux, G.S. Robertson, R. Zamboni, D.W. Nicholson, and D.M. Holtzman Selective, reversible caspase-3 inhibitor is neuroprotective and reveals distinct pathways of cell death after neonatal hypoxic-ischemic brain injury Journal of Biological Chemistry 277 2002 30128 30136
13. R. Hata, F. Gillardon, T.M. Michaelidis, and K.A. Hossmann Targeted disruption of the bcl-2 gene in mice exacerbates focal ischemic brain injury Metabolic Brain Disease 14 1999 117 124 (Pubitemid 29418694)
14. W.K. Ho, H.L. Wen, and C.M. Lee Tetramethylpyrazine for treatment of experimentally induced stroke in Mongolian gerbils Stroke 20 1989 96 99 (Pubitemid 19040220)
15. J. Huang, U.M. Upadhyay, and R.J. Tamargo Inflammation in stroke and focal cerebral ischemia Surgical Neurology 66 2006 232 245 (Pubitemid 44279808)
16. K.J. Ivins, E.T. Bui, and C.W. Cotman Beta-amyloid induces local neurite degeneration in cultured hippocampal neurons: evidence for neuritic apoptosis Neurobiology of Disease 5 1998 365 378 (Pubitemid 29037288)
17. D.A. Le, Y. Wu, Z. Huang, K. Matsushita, N. Plesnila, J.C. Augustinack, B.T. Hyman, J. Yuan, K. Kuida, R.A. Flavell, and M.A. Moskowitz Caspase activation and neuroprotection in caspase-3-deficient mice after in vivo cerebral ischemia and in vitro oxygen glucose deprivation Proceedings of the National Academy of Sciences of the United States of America 99 2002 15188 15193 (Pubitemid 35334631)
18. K.Z. Liu, J.B. Li, H.L. Lu, J.K. Wen, and M. Han Effects of Astragalus and saponins of Panax notoginseng on MMP-9 in patients with type 2 diabetic macroangiopathy Zhongguo Zhong Yao Za Zhi 29 2004 264 266
19. E.Z. Longa, P.R. Weinstein, S. Carlson, and R. Cummins Reversible middle cerebral artery occlusion without craniectomy in rats Stroke 20 1989 84 91 (Pubitemid 19040218)
20. B. Lubec, M. Chiappe-Gutierrez, H. Hoeger, E. Kitzmueller, and G. Lubec Glucose transporters, hexokinase, and phosphofructokinase in brain of rats with perinatal asphyxia Pediatric Research 47 2000 84 88 (Pubitemid 30038896)
21. Y. Luo, Z. Qin, Z. Hong, X. Zhang, D. Ding, J.H. Fu, W.D. Zhang, and J. Chen Astragaloside IV protects against ischemic brain injury in a murine model of transient focal ischemia Neuroscience Letters 363 2004 218 223 (Pubitemid 38746516)
22. M.A. Moro, A. Almeida, J.P. Bolanos, and I. Lizasoain Mitochondrial respiratory chain and free radical generation in stroke Free Radical Biology and Medicine 39 2005 1291 1304 (Pubitemid 41540085)
23. S. Namura, J. Zhu, K. Fink, M. Endres, A. Srinivasan, K.J. Tomaselli, J. Yuan, and M.A. Moskowitz Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia Journal of Neuroscience 18 1998 3659 3668 (Pubitemid 28225674)
24. Y.Z. Qu, M. Li, Y.L. Zhao, Z.W. Zhao, X.Y. Wei, J.P. Liu, L. Gao, and G.D. Gao Astragaloside IV attenuates cerebral ischemia-reperfusion-induced increase in permeability of the blood-brain barrier in rats European Journal of Pharmacology 606 2009 137 141
25. S.J. Read, T. Hirano, D.F. Abbott, J.I. Sachinidis, H.J. Tochon-Danguy, J.G. Chan, G.F. Egan, A.M. Scott, C.F. Bladin, W.J. McKay, and G.A. Donnan Identifying hypoxic tissue after acute ischemic stroke using PET and 18F-fluoromisonidazole Neurology 51 1998 1617 1621
26. E.M. Rohren, T.G. Turkington, and R.E. Coleman Clinical applications of PET in oncology Radiology 231 2004 305 332 (Pubitemid 38552885)
27. A.S. Sarrafzadeh, A. Nagel, M. Czabanka, T. Denecke, P. Vajkoczy, and M. Plotkin Imaging of hypoxic-ischemic penumbra with (18)F-fluoromisonidazole PET/CT and measurement of related cerebral metabolism in aneurysmal subarachnoid hemorrhage Journal of Cerebral Blood Flow and Metabolism 30 2010 36 45
28. B. Schaller, and R. Graf Cerebral ischemia and reperfusion: the pathophysiologic concept as a basis for clinical therapy Journal of Cerebral Blood Flow and Metabolism 24 2004 351 371 (Pubitemid 38452228)
29. A.R. Shahed, E. Jones, and D. Shoskes Quercetin and curcumin up-regulate antioxidant gene expression in rat kidney after ureteral obstruction or ischemia/reperfusion injury Transplantation Proceedings 33 2001 2988 (Pubitemid 32785622)
30. B.M. Shao, W. Xu, H. Dai, P. Tu, Z. Li, and X.M. Gao A study on the immune receptors for polysaccharides from the roots of Astragalus membranaceus, a Chinese medicinal herb Biochemical and Biophysical Research Communications 320 2004 1103 1111 (Pubitemid 38916657)
31. I. Solaroglu, T. Tsubokawa, J. Cahill, and J.H. Zhang Anti-apoptotic effect of granulocyte-colony stimulating factor after focal cerebral ischemia in the rat Neuroscience 143 2006 965 974 (Pubitemid 44827523)
32. C.J. Vaughan, and N. Delanty Neuroprotective properties of statins in cerebral ischemia and stroke Stroke 30 1999 1969 1973 (Pubitemid 29411843)
33. H. Wan, H. Zhu, M. Tian, X. Hu, J. Yang, C. Zhao, and H. Zhang Protective effect of chuanxiongzine-puerarin in a rat model of transient middle cerebral artery occlusion-induced focal cerebral ischemia Nuclear Medicine Communications 29 2008 1113 1122
34. B. Xing, H. Chen, M. Zhang, D. Zhao, R. Jiang, X. Liu, and S. Zhang Ischemic postconditioning inhibits apoptosis after focal cerebral ischemia/reperfusion injury in the rat Stroke 39 2008 2362 2369
35. H. Zhang, X. Zheng, X. Yang, S. Fang, G. Shen, C. Zhao, and M. Tian 11C-NMSP/18F-FDG microPET to monitor neural stem cell transplantation in a rat model of traumatic brain injury European Journal of Nuclear Medicine and Molecular Imaging 35 2008 1699 1708
36. W.J. Zhang, P. Hufnagl, B.R. Binder, and J. Wojta Antiinflammatory activity of astragaloside IV is mediated by inhibition of NF-kappaB activation and adhesion molecule expression Thrombosis and Haemostasis 90 2003 904 914 (Pubitemid 37427861)
37. C. Zhao, Z. Chen, X. Ye, Y. Zhang, H. Zhan, T. Aburano, M. Tian, and H. Zhang Imaging a pancreatic carcinoma xenograft model with 11C-acetate: a comparison study with 18F-FDG Nuclear Medicine Communications 30 2009 971 977
38. H. Zhou, Y. Ma, Y. Zhou, Z. Liu, K. Wang, and G. Chen Effects of magnesium sulfate on neuron apoptosis and expression of caspase-3, bax and bcl-2 after cerebral ischemia-reperfusion injury Chinese Medical Journal 116 2003 1532 1534 (Pubitemid 37461672)