메뉴 건너뛰기




Volumn 57, Issue 8, 2005, Pages 1059-1064

Gastroprotective effect of Astragaloside IV: Role of prostaglandins, sulfhydryls and nitric oxide

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; ANTIULCER AGENT; ASTRAGALOSIDE IV; CARBENOXOLONE; GLYCOSIDE; INDOMETACIN; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; PLANT EXTRACT; PROSTAGLANDIN; THIOL DERIVATIVE; TRITERPENE; UNCLASSIFIED DRUG;

EID: 22844435412     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/0022357056659     Document Type: Article
Times cited : (45)

References (34)
  • 2
    • 0348107351 scopus 로고    scopus 로고
    • Purification of gastroprotective triterpenoids from the stem bark of Amphipterygium adstringens; role of prostaglandins, sulfhydryls, nitric oxide and capsaicin-sensitive neurons
    • Arrieta, J., Benitez, J., Flores, E., Castillo, C., Navarrete, A. (2003) Purification of gastroprotective triterpenoids from the stem bark of Amphipterygium adstringens; role of prostaglandins, sulfhydryls, nitric oxide and capsaicin-sensitive neurons. Planta Med. 69: 905-909
    • (2003) Planta Med. , vol.69 , pp. 905-909
    • Arrieta, J.1    Benitez, J.2    Flores, E.3    Castillo, C.4    Navarrete, A.5
  • 3
    • 0033670696 scopus 로고    scopus 로고
    • The plant kingdom as a source of anti-ulcer remedies
    • Borrelli, F., Izzo, A. A. (2000) The plant kingdom as a source of anti-ulcer remedies. Phytother. Res. 14: 581-591
    • (2000) Phytother. Res. , vol.14 , pp. 581-591
    • Borrelli, F.1    Izzo, A.A.2
  • 4
    • 0030747212 scopus 로고    scopus 로고
    • Role of L-arginine, a substrate for nitric oxide-synthase, in gastroprotection and ulcer healing
    • Brzozowski, T., Konturek, S. J., Sliwowski, Z., Drozdowicz, D., Zaczek, M., Kedra, D. (1997) Role of L-arginine, a substrate for nitric oxide-synthase, in gastroprotection and ulcer healing. J. Gastroenterol. 32: 442-452
    • (1997) J. Gastroenterol. , vol.32 , pp. 442-452
    • Brzozowski, T.1    Konturek, S.J.2    Sliwowski, Z.3    Drozdowicz, D.4    Zaczek, M.5    Kedra, D.6
  • 5
    • 0035368275 scopus 로고    scopus 로고
    • Nitric oxide: Relation to integrity, injury, and healing of the gastric mucosa
    • Calatayud, S., Borrachina, M. D., Espulgues, J. V. (2001) Nitric oxide: relation to integrity, injury, and healing of the gastric mucosa. Microsc. Res. Tech. 53: 325-335
    • (2001) Microsc. Res. Tech. , vol.53 , pp. 325-335
    • Calatayud, S.1    Borrachina, M.D.2    Espulgues, J.V.3
  • 7
    • 0034795999 scopus 로고    scopus 로고
    • Secondary metabolites from the roots of Astragalus zahlbruckneri
    • Calis, I., Abou-Gazar, H., Piacente, S., Pizza, C. (2001) Secondary metabolites from the roots of Astragalus zahlbruckneri. J. Nat. Prod. 64: 1179-1182
    • (2001) J. Nat. Prod. , vol.64 , pp. 1179-1182
    • Calis, I.1    Abou-Gazar, H.2    Piacente, S.3    Pizza, C.4
  • 8
    • 0036128096 scopus 로고    scopus 로고
    • A comparative study on the activity of lansoprazole, omeprazole and PD-13450 on acidified ethanol- and indomethacin-induced gastric lesions in the rat
    • Chandranath, S. I., Bastaki, S. M. A., Singh, J. (2002) A comparative study on the activity of lansoprazole, omeprazole and PD-13450 on acidified ethanol- and indomethacin-induced gastric lesions in the rat. Clin. Exp. Pharmacol. Physiol. 29: 173-180
    • (2002) Clin. Exp. Pharmacol. Physiol. , vol.29 , pp. 173-180
    • Chandranath, S.I.1    Bastaki, S.M.A.2    Singh, J.3
  • 9
    • 0036200727 scopus 로고    scopus 로고
    • G-nitro-L-arginine methyl ester and L-arginine on gastric mucosal tolerant cytoprotection under stress
    • G-nitro-L-arginine methyl ester and L-arginine on gastric mucosal tolerant cytoprotection under stress. Chin. J. Dig. Dis. 3: 1-6
    • (2002) Chin. J. Dig. Dis. , vol.3 , pp. 1-6
    • Cui, Z.M.1    Li, Z.S.2    Xu, G.M.3    Zhan, X.B.4
  • 10
    • 0343826847 scopus 로고    scopus 로고
    • Role of nitric oxide in gastric injury induced by hemorrhagic shock in rats
    • Denizbasi, A., Yagen, C., Ozturk, M., Yegen, B.(2000) Role of nitric oxide in gastric injury induced by hemorrhagic shock in rats. Pharmacology 61: 106-112
    • (2000) Pharmacology , vol.61 , pp. 106-112
    • Denizbasi, A.1    Yagen, C.2    Ozturk, M.3    Yegen, B.4
  • 11
    • 0032457409 scopus 로고    scopus 로고
    • Nitric oxide: A regulator of mucosal defense and injury
    • Elliott, S. N., Wallace, J. L. (1998) Nitric oxide: a regulator of mucosal defense and injury. J. Gastroenterol. 33: 792-803
    • (1998) J. Gastroenterol. , vol.33 , pp. 792-803
    • Elliott, S.N.1    Wallace, J.L.2
  • 12
    • 10844291495 scopus 로고    scopus 로고
    • Transport and bioavailability studies of Astragaloside IV, an active ingredient in Radix Astragali
    • Gu, Y., Wang, G., Pan, G., Fawcett, J. P., Jiye, A., Sun, J. (2004) Transport and bioavailability studies of Astragaloside IV, an active ingredient in Radix Astragali. Basic Clin. Pharmacol. Toxicol. 95: 295-298
    • (2004) Basic Clin. Pharmacol. Toxicol. , vol.95 , pp. 295-298
    • Gu, Y.1    Wang, G.2    Pan, G.3    Fawcett, J.P.4    Jiye, A.5    Sun, J.6
  • 13
    • 0020628166 scopus 로고
    • Saponin and sapogenol. XXXV. Chemical constituents of Astragali Radix, the root of Astragalus mambranaceus Bunge (2). Astragalosides I, II and IV, acetylastragaloside I and Isoastragalosides I and II
    • Kitagawa, I., Kang, H., Saito, M., Takagi, A., Yoshikawa, M. (1983) Saponin and sapogenol. XXXV. Chemical constituents of Astragali Radix, the root of Astragalus mambranaceus Bunge (2). Astragalosides I, II and IV, acetylastragaloside I and Isoastragalosides I and II. Chem. Pharm. Bull. 31: 698-708
    • (1983) Chem. Pharm. Bull. , vol.31 , pp. 698-708
    • Kitagawa, I.1    Kang, H.2    Saito, M.3    Takagi, A.4    Yoshikawa, M.5
  • 15
    • 0026362315 scopus 로고
    • Anti-ulcer drugs of plant origin
    • Lewis, D., Hanson, P. J. (1991) Anti-ulcer drugs of plant origin. Prog. Med. Chem. 28: 201-231
    • (1991) Prog. Med. Chem. , vol.28 , pp. 201-231
    • Lewis, D.1    Hanson, P.J.2
  • 16
    • 2942596217 scopus 로고    scopus 로고
    • Astragaloside IV protects against ischemic brain injury in a murine model of transient focal ischemia
    • Luo, Y., Qin, Z., Hong, Z., Zhang, X., Ding, D., Fu, J. H., Zhang, W. D., Chen, J. (2004) Astragaloside IV protects against ischemic brain injury in a murine model of transient focal ischemia. Neurosci. Lett. 363: 218-223
    • (2004) Neurosci. Lett. , vol.363 , pp. 218-223
    • Luo, Y.1    Qin, Z.2    Hong, Z.3    Zhang, X.4    Ding, D.5    Fu, J.H.6    Zhang, W.D.7    Chen, J.8
  • 18
    • 0027498013 scopus 로고
    • Anti-ulcerogenic activity of aescine in different experimental models
    • Marhuenda, E., Martin, M. J., Alarcon de la Lastra, C. (1993) Anti-ulcerogenic activity of aescine in different experimental models. Phytother. Res. 7: 13-16
    • (1993) Phytother. Res. , vol.7 , pp. 13-16
    • Marhuenda, E.1    Martin, M.J.2    Alarcon De La Lastra, C.3
  • 19
    • 0033522839 scopus 로고    scopus 로고
    • Roles of capsaicin-sensitive sensory nerves, endogenous nitric oxide, sulfhydryls, and prostaglandins in gastroprotection by momordin Ic, an oleanolic acid oligoglycoside, on ethanol-induced gastric mucosal lesions in rats
    • Matsuda, H., Li, Y., Yoshikawa, M. (1999) Roles of capsaicin-sensitive sensory nerves, endogenous nitric oxide, sulfhydryls, and prostaglandins in gastroprotection by momordin Ic, an oleanolic acid oligoglycoside, on ethanol-induced gastric mucosal lesions in rats. Life Sci. 65: PL27-PL32
    • (1999) Life Sci. , vol.65
    • Matsuda, H.1    Li, Y.2    Yoshikawa, M.3
  • 20
    • 0031930867 scopus 로고    scopus 로고
    • Gastroprotective activity of the stem bark of Amphipterygium adstringens in rats
    • Navarrete, A., Martínez-Uribe, L. S., Reyes, B. (1998) Gastroprotective activity of the stem bark of Amphipterygium adstringens in rats. Phytother. Res. 12: 1-4
    • (1998) Phytother. Res. , vol.12 , pp. 1-4
    • Navarrete, A.1    Martínez-Uribe, L.S.2    Reyes, B.3
  • 21
    • 0036181214 scopus 로고    scopus 로고
    • Principles of root bark of Hippocratea excelsa (Hippocrataceae) with gastroprotective activity
    • Navarrete, A., Trejo-Miranda, J. L., Reyes-Trejo, L. J. (2002) Principles of root bark of Hippocratea excelsa (Hippocrataceae) with gastroprotective activity. J. Ethnopharmacol. 79: 383-388
    • (2002) J. Ethnopharmacol. , vol.79 , pp. 383-388
    • Navarrete, A.1    Trejo-Miranda, J.L.2    Reyes-Trejo, L.J.3
  • 23
    • 0034805488 scopus 로고    scopus 로고
    • Inhibition of trypsin and chymotrypsin by anti-inflammatory triterpenoids from Compositae flowers
    • Rajic, A., Akihisa, T., Ukiya, M., Yasukawa, K., Sandeman, R. M., Chandler, D. S., Polya, G. M. (2001) Inhibition of trypsin and chymotrypsin by anti-inflammatory triterpenoids from Compositae flowers. Planta Med. 67: 599-604
    • (2001) Planta Med. , vol.67 , pp. 599-604
    • Rajic, A.1    Akihisa, T.2    Ukiya, M.3    Yasukawa, K.4    Sandeman, R.M.5    Chandler, D.S.6    Polya, G.M.7
  • 24
    • 0030797894 scopus 로고    scopus 로고
    • A review of the pharmacology and toxicology of Astragalus
    • Rios, J. L., Waterman, P. G. (1997) A review of the pharmacology and toxicology of Astragalus. Phytother. Res. 11: 411-418
    • (1997) Phytother. Res. , vol.11 , pp. 411-418
    • Rios, J.L.1    Waterman, P.G.2
  • 25
    • 0018292487 scopus 로고
    • Cytoprotection by prostaglandins
    • Robert, A. (1979) Cytoprotection by prostaglandins. Gastroenterology 77: 761-767
    • (1979) Gastroenterology , vol.77 , pp. 761-767
    • Robert, A.1
  • 26
    • 0019825246 scopus 로고
    • Sulfhydryl compounds may mediate gastric cytoprotection
    • Szabo, S., Trier, J. S., Frankel, P. W. (1981) Sulfhydryl compounds may mediate gastric cytoprotection. Science 214: 200-2002
    • (1981) Science , vol.214 , pp. 200-2002
    • Szabo, S.1    Trier, J.S.2    Frankel, P.W.3
  • 28
    • 0021967436 scopus 로고
    • Cytoprotective action of carbenoxolone sodium on ethanol-induced gastric lesions in rats and its inhibition by indomethacin
    • Wan, B., Gottfried, S. (1985) Cytoprotective action of carbenoxolone sodium on ethanol-induced gastric lesions in rats and its inhibition by indomethacin. J. Pharm. Pharmacol 37: 739-741
    • (1985) J. Pharm. Pharmacol , vol.37 , pp. 739-741
    • Wan, B.1    Gottfried, S.2
  • 29
    • 0027216741 scopus 로고
    • Action and interaction of endothelins, protacyclin and nitric oxide in the gastric mucosa
    • Whittle, B. J. R., Lopez-Belmonte, J. (1993) Action and interaction of endothelins, protacyclin and nitric oxide in the gastric mucosa. J. Physiol. Pharmacol. 44: 91-107
    • (1993) J. Physiol. Pharmacol. , vol.44 , pp. 91-107
    • Whittle, B.J.R.1    Lopez-Belmonte, J.2
  • 30
    • 0025034767 scopus 로고
    • Regulation of gastric mucosal integrity by endogenous nitric oxide: Interaction with prostanoids and sensory neuropeptides in the rat
    • Whittle, B. J. R., Lopez-Belmonte, J., Moncada, S. (1990) Regulation of gastric mucosal integrity by endogenous nitric oxide: interaction with prostanoids and sensory neuropeptides in the rat. Br. J. Pharmacol. 99: 607-611
    • (1990) Br. J. Pharmacol. , vol.99 , pp. 607-611
    • Whittle, B.J.R.1    Lopez-Belmonte, J.2    Moncada, S.3
  • 31
    • 0034847958 scopus 로고    scopus 로고
    • Antinociceptive effect of astragalosides and its mechanism of action
    • Yang, Q., Lu, J. T., Zhou, A. W., Wang, B., He, G. W., Chen, M. Z. (2001) Antinociceptive effect of astragalosides and its mechanism of action. Acta Pharmacol. Sin. 22: 809-812
    • (2001) Acta Pharmacol. Sin. , vol.22 , pp. 809-812
    • Yang, Q.1    Lu, J.T.2    Zhou, A.W.3    Wang, B.4    He, G.W.5    Chen, M.Z.6
  • 32
    • 9644300893 scopus 로고    scopus 로고
    • Effects of triterpenes from Astragalus species on in vitro cytokine release
    • Yesilada, E., Bedir, E., Calis, I., Takaishi, Y., Ohmoto, Y. (2005) Effects of triterpenes from Astragalus species on in vitro cytokine release. J. Ethnopharmacol. 96: 71-77
    • (2005) J. Ethnopharmacol. , vol.96 , pp. 71-77
    • Yesilada, E.1    Bedir, E.2    Calis, I.3    Takaishi, Y.4    Ohmoto, Y.5
  • 33
    • 0242606426 scopus 로고    scopus 로고
    • Antiinflammatory activity of astragaloside IV is mediated by inhibition of NF-κB activation and adhesion molecule expression
    • Zhang, W. J., Hufnagl, P., Binder, B. R., Wojta, J. (2003) Antiinflammatory activity of astragaloside IV is mediated by inhibition of NF-κB activation and adhesion molecule expression. Thromb. Hemost. 90: 904-914
    • (2003) Thromb. Hemost. , vol.90 , pp. 904-914
    • Zhang, W.J.1    Hufnagl, P.2    Binder, B.R.3    Wojta, J.4
  • 34
    • 23644452505 scopus 로고    scopus 로고
    • Effects of components isolated from Astragalus membranaceus Bunge on cardiac function injured by myocardial ischemia reperfusion in rats
    • Zhou, J. Y., Fan, Y., Kong, J. L., Wu, D. Z., Hu, Z. B. (2000) Effects of components isolated from Astragalus membranaceus Bunge on cardiac function injured by myocardial ischemia reperfusion in rats. Zhongguo Zhong Yao Za Zhi. 25: 300-302
    • (2000) Zhongguo Zhong Yao Za Zhi , vol.25 , pp. 300-302
    • Zhou, J.Y.1    Fan, Y.2    Kong, J.L.3    Wu, D.Z.4    Hu, Z.B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.