Astragali Radix elicits anti-inflammation via activation of MKP-1, concomitant with attenuation of p38 and Erk

Journal of Ethnopharmacology

Volumn 115, Issue 2, 2008, Pages 184-193

  Ryu, Minsook ^a   Kim, Eun Hye ^b   Chun, Mison ^c   Kang, Seunghee ^c   Shim, Bumsang ^d   Yu, Young Beob ^e   Jeong, Gajin ^b   Lee, Jong Soo ^a  

^a Ajou University   (South Korea)

^b Seoul National University   (South Korea)

^c Ajou University School of Medicine   (South Korea)

^d Kyung Hee University   (South Korea)

^e Korea Institute of Oriental Medicine (KIOM)   (South Korea)

Author keywords

Anti inflammation; Astragali Radix; Erk1 2; Mitogen activated protein kinase phosphatase 1; NF B; p38

Indexed keywords

ANTIINFLAMMATORY AGENT; ASTRAGALI RADIX EXTRACTS; ASTRAGALUS EXTRACT; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; NITRIC OXIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ZYMOSAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; FEMALE; INFLAMMATION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; TRANSCRIPTION REGULATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ASTRAGALUS MEMBRANACEUS; DUAL SPECIFICITY PHOSPHATASE 1; FEMALE; GENE EXPRESSION REGULATION; INFLAMMATION; MEDICINE, ORIENTAL TRADITIONAL; MICE; MICE, INBRED BALB C; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PLANT EXTRACTS; PLANT ROOTS; TRANSCRIPTION, GENETIC;

ASTRAGALUS MEMBRANACEUS; MUS;

EID: 37249028093     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2007.09.027     Document Type: Article

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