Effect of the antifibrillatory compound tedisamil (KC-8857) on transmembrane currents in mammalian ventricular myocytes

Current Medicinal Chemistry

Volumn 11, Issue 24, 2004, Pages 3219-3228

  Jost, N ^a,b   Virag L ^a   Hala O ^a   Varro A ^a   Thormahlen D ^c   Papp, J Gy ^a,b  

^a UNIVERSITY OF SZEGED   (Hungary)

^b INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^c Solvay Pharmaceuticals GmbH   (Germany)

Author keywords

Cardiomyocytes; Cellular mechanism of action; Tedisamil (KC 8857); Transmembrane ion currents

Indexed keywords

1 [2 (6 METHYL 2 PYRIDYL)ETHYL] 4 (4 METHYLSULFONYLAMINOBENZOYL)PIPERIDINE; ANTIARRHYTHMIC AGENT; CALCIUM; CHROMANOL 293B; CROMAKALIM; GLIBENCLAMIDE; NISOLDIPINE; POTASSIUM; SODIUM; TEDISAMIL;

ACCELERATION; ACTION POTENTIAL; ALPHA CHAIN; ANIMAL CELL; ANTIARRHYTHMIC ACTIVITY; ARTICLE; CALCIUM CURRENT; CELL ACTIVATION; CELL KINETICS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOG; DRUG CLASSIFICATION; DRUG MECHANISM; DRUG POTENCY; DRUG STRUCTURE; GUINEA PIG; HEART MUSCLE CELL; HEART VENTRICLE; MEMBRANE CURRENT; MICROELECTRODE; NONHUMAN; PATCH CLAMP; POTASSIUM CURRENT; RABBIT; SODIUM CURRENT; STATISTICAL SIGNIFICANCE;

EID: 8844228183     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/0929867043363631     Document Type: Article

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