High membrane potential promotes alkenal-induced mitochondrial uncoupling and influences adenine nucleotide translocase conformation

Biochemical Journal

Volumn 413, Issue 2, 2008, Pages 323-332

  Azzu, Vian ^a   Parker, Nadeene ^a   Brand, Martin D ^a  

^a WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

Author keywords

4 hydroxynonenal (HNE); Carboxyatractylate (CAtr); Proton leak; Rat liver mitochondrion; Trypsin

Indexed keywords

CHEMICAL REACTIONS; ELECTRIC POWER PLANTS; LEAKAGE (FLUID); MITOCHONDRIA; NONMETALS; NUCLEIC ACIDS; OXYGEN; PHOSPHORYLATION; PROTEINS; PROTONS;

4-HYDROXY-NONENAL; ADDUCT FORMATION; ADENINE NUCLEOTIDE TRANSLOCASE; CARBOXYATRACTYLATE; ENERGIZATION; LIPID PEROXIDATION (MDA); MEMBRANE POTENTIALS; MITOCHONDRIAL INNER MEMBRANES; OXIDATIVE PHOSPHORYLATION; PROTON LEAK; RAT LIVERS; REACTIVE OXYGEN SPECIES (ROS); TRANSLOCASE; TRANSLOCATION PATHWAYS; UNCOUPLING (UCP) PROTEIN;

NUCLEOTIDES;

4 HYDROXYNONENAL; ADENINE NUCLEOTIDE TRANSLOCASE; CARBOXYATRACTYLIC ACID; CARBOXYL GROUP; 4-HYDROXY-2-NONENAL; ALDEHYDE; NUCLEOTIDE; PROTON;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; GENE TRANSLOCATION; INCUBATION TIME; LIVER MITOCHONDRION; MEMBRANE POTENTIAL; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTON TRANSPORT; RESPIRATION CONTROL; ANIMAL; CELL MEMBRANE POTENTIAL; CHEMISTRY; KINETICS; METABOLISM; MITOCHONDRION; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; RAT; TRANSPORT AT THE CELLULAR LEVEL;

RATTUS;

ALDEHYDES; ANIMALS; BIOLOGICAL TRANSPORT; FEMALE; KINETICS; MEMBRANE POTENTIALS; MITOCHONDRIA; MITOCHONDRIA, LIVER; MITOCHONDRIAL ADP, ATP TRANSLOCASES; NUCLEOTIDES; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; PROTEIN CONFORMATION; PROTONS; RATS;

EID: 48149092833     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20080321     Document Type: Article

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