Glutathione decreases in dopaminergic PC12 cells interfere with the ubiquitin protein degradation pathway: Relevance for Parkinson's disease?

Journal of Neurochemistry

Volumn 80, Issue 4, 2002, Pages 555-561

  Jha, Nandita ^a   Kumar, M Jyothi ^a   Boonplueang, Rapee ^a   Andersen, Julie K ^a  

^a BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

Author keywords

Parkinson's disease; Protein degradation; Thiol oxidation; Total glutathione; Ubiquitin E1 ligase

Indexed keywords

E1 UBIQUITIN LIGASE; GLUTATHIONE; PROTEASOME; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DEATH; CELL LEVEL; CELL STRAIN; CONJUGATION; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; ENZYME ACTIVE SITE; ENZYME ACTIVITY; LEWY BODY; MESENCEPHALON; NERVE CELL DEGENERATION; NONHUMAN; OXIDATION; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION;

ANIMALS; CELL LINE; DNA, ANTISENSE; DOPAMINE; DOXYCYCLINE; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE; HYDROGEN PEROXIDE; LIGASES; MACROMOLECULAR SUBSTANCES; PARKINSON DISEASE; PC12 CELLS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEINS; RATS; SULFHYDRYL COMPOUNDS; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES;

ANIMALIA;

EID: 0036329641     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0022-3042.2001.00009.x     Document Type: Article

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