Mitochondrial effects of the pleiotropic proteasomal mutation mpr1/rpn11: Uncoupling from cell cycle defects in extragenic revertants

Gene

Volumn 286, Issue 1, 2002, Pages 43-51

  Rinaldi, T ^a   Ricordy, R ^b   Bolotin Fukuhara, M ^c   Frontali, L ^a  

^a Pasteur Institute   (Italy)

^b CNR   (Italy)

^c UNIVERSITÉ PARIS SACLAY   (France)

Author keywords

Cell cycle; Mitochondrial morphology; Proteasome; Saccharomyces cerevisiae

Indexed keywords

GLUCOSE; GLYCEROL; PROTEASOME; UBIQUITIN;

CELL CYCLE; CONFERENCE PAPER; CONTROLLED STUDY; GENE FUNCTION; GENE MUTATION; GENE REPRESSION; HEAT SENSITIVITY; MITOCHONDRION; MUTANT; NONHUMAN; PHENOTYPE; PLEIOTROPY; PRIORITY JOURNAL; REVERTANT; SACCHAROMYCES CEREVISIAE; TEMPERATURE SENSITIVE MUTANT;

AMINO ACID SEQUENCE; CELL CYCLE; CELL CYCLE PROTEINS; CYSTEINE ENDOPEPTIDASES; ENDOPEPTIDASES; MICROSCOPY, CONFOCAL; MITOCHONDRIA; MOLECULAR SEQUENCE DATA; MULTIENZYME COMPLEXES; MUTATION; PROTEASOME ENDOPEPTIDASE COMPLEX; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SUPPRESSION, GENETIC;

SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0037029053     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(01)00799-5     Document Type: Conference Paper

References (25)

1. Patterns of mitochondrial sorting in yeast zygotes
2. The proteasome: Paradigm of a self-compartmentalizing protease
3. Mitochondrial morphological and functional defects in yeast caused by yme1 are suppressed by mutation of a 26S protease subunit homologue
4. Gag3p, an outer membrane protein required for fission of mitochondrial tubules
5. A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9-signalosome and elF3
6. The regulatory particle of the S. cerevisiae proteasome
7. Structure of 20S proteasome from yeast at a 2.4 Å resolution
8. Roles of ubiquitin-mediated proteolysis in cell cycle control
9. Proteasome: Destruction as a programme
10. How proteolysis drives the cell cycle
11. Interorganelle signaling is a determinant of longevity in Saccharomyces cerevisiae
12. ASC1/RAS2 suppresses the growth defect on glycerol caused by the atp1-2 mutation in the yeast Saccharomyces cerevisiae
13. Fluorescence microscopy studies of mitochondrial nucleoids during meiosis and sporulation in yeast Saccharomyces cerevisiae
14. Proteasome-mediated degradation of transcriptional activators correlates with activation domain potency in vivo
15. Dnm1p GTPase-mediated mitochondrial fission is a multi-step process requiring the novel integral membrane component Fis1p
16. Mitochondrial transmission during mating in Saccharomyces cerevisiae is determined by mitochondrial fusion and fission and the intramitochondrial segregation of mitochondrial DNA
17. Endoplasmic reticulum degradation of a mutated ATP-binding cassette transporter Pdr5 proceeds in a concerted action of Sec61 and the proteasome
18. A mutation in a novel yeast proteasomal gene, RPN11/MPR1, produces a cell cycle arrest, overreplication of nuclear and mitochondrial DNA, and an altered mitochondrial morphology
19. The proteasome regulates the UV-induced activation of the AP-1-like transcription factor Gcn4
20. Inactivation of YME1, a member of the ftsH-SEC18-PAS1-CDC48 family of putative ATPase-encoding genes, causes increased escape of DNA from mitochondria in Saccharomyces cerevisiae
21. Mdv1p is a WD repeat protein that interacts with the dynamin-related GTPase, Dnm1p, to trigger mitochondrial division
22. A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae
23. The dynamin-related GTPase, Mgm1p, is an intermembrane space protein required for maintenance of fusion competent mitochondria
24. The machinery of mitochondrial inheritance and behaviour