-
1
-
-
34047181415
-
Abeta, tau and ApoE4 in Alzheimer's disease: the axonal connection
-
Adalbert R, Gilley J, Coleman MP. 2007. Abeta, tau and ApoE4 in Alzheimer's disease: the axonal connection. Trends Mol Med 13: 135-142.
-
(2007)
Trends Mol Med
, vol.13
, pp. 135-142
-
-
Adalbert, R.1
Gilley, J.2
Coleman, M.P.3
-
2
-
-
60149092294
-
Severely dystrophic axons at amyloid plaques remain continuous and connected to viable cell bodies
-
Adalbert R, Nogradi A, Babetto E, Janeckova L, Walker SA, Kerschensteiner M, Misgeld T, Coleman MP. 2009. Severely dystrophic axons at amyloid plaques remain continuous and connected to viable cell bodies. Brain 132: 402-416.
-
(2009)
Brain
, vol.132
, pp. 402-416
-
-
Adalbert, R.1
Nogradi, A.2
Babetto, E.3
Janeckova, L.4
Walker, S.A.5
Kerschensteiner, M.6
Misgeld, T.7
Coleman, M.P.8
-
3
-
-
0032144463
-
Dendritic changes in Alzheimer's disease and factors that may underlie these changes
-
Anderton BH, Callahan L, Coleman P, Davies P, Flood D, Jicha GA, Ohm T, Weaver C. 1998. Dendritic changes in Alzheimer's disease and factors that may underlie these changes. Prog Neurobiol 55: 595-609.
-
(1998)
Prog Neurobiol
, vol.55
, pp. 595-609
-
-
Anderton, B.H.1
Callahan, L.2
Coleman, P.3
Davies, P.4
Flood, D.5
Jicha, G.A.6
Ohm, T.7
Weaver, C.8
-
5
-
-
78649498235
-
Multiple events lead to dendritic spine loss in triple transgenic Alzheimer's disease mice
-
Bittner T, Fuhrmann M, Burgold S, Ochs SM, Hoffmann N, Mitteregger G, Kretzschmar H, LaFerla FM, Herms J. 2010. Multiple events lead to dendritic spine loss in triple transgenic Alzheimer's disease mice. PLoS One 5: e15477.
-
(2010)
PLoS One
, vol.5
-
-
Bittner, T.1
Fuhrmann, M.2
Burgold, S.3
Ochs, S.M.4
Hoffmann, N.5
Mitteregger, G.6
Kretzschmar, H.7
LaFerla, F.M.8
Herms, J.9
-
6
-
-
84878351215
-
Amyloid plaque formation precedes dendritic spine loss
-
Bittner T, Burgold S, Dorostkar MM, Fuhrmann M, Wegenast-Braun BM, Schmidt B, Kretzschmar H, Herms J. 2012. Amyloid plaque formation precedes dendritic spine loss. Acta Neuropathol 124: 797-807.
-
(2012)
Acta Neuropathol
, vol.124
, pp. 797-807
-
-
Bittner, T.1
Burgold, S.2
Dorostkar, M.M.3
Fuhrmann, M.4
Wegenast-Braun, B.M.5
Schmidt, B.6
Kretzschmar, H.7
Herms, J.8
-
7
-
-
80055026234
-
Abnormal tau phosphorylation in the thorny excrescences of CA3 hippocampal neurons in patients with Alzheimer's disease
-
Blazquez-Llorca L, Garcia-Marin V, Merino-Serrais P, Avila J, DeFelipe J. 2011. Abnormal tau phosphorylation in the thorny excrescences of CA3 hippocampal neurons in patients with Alzheimer's disease. J Alzheimers Dis 26: 683-698.
-
(2011)
J Alzheimers Dis
, vol.26
, pp. 683-698
-
-
Blazquez-Llorca, L.1
Garcia-Marin, V.2
Merino-Serrais, P.3
Avila, J.4
DeFelipe, J.5
-
8
-
-
42949175211
-
Dynamics of the microglial/amyloid interaction indicate a role in plaque maintenance
-
Bolmont T, Haiss F, Eicke D, Radde R, Mathis CA, Klunk WE, Kohsaka S, Jucker M, Calhoun ME. 2008. Dynamics of the microglial/amyloid interaction indicate a role in plaque maintenance. J Neurosci 28: 4283-4292.
-
(2008)
J Neurosci
, vol.28
, pp. 4283-4292
-
-
Bolmont, T.1
Haiss, F.2
Eicke, D.3
Radde, R.4
Mathis, C.A.5
Klunk, W.E.6
Kohsaka, S.7
Jucker, M.8
Calhoun, M.E.9
-
9
-
-
0037450356
-
PDAPP; YFP double transgenic mice: a tool to study amyloid-beta associated changes in axonal, dendritic, and synaptic structures
-
Brendza RP, O'Brien C, Simmons K, McKeel DW, Bales KR, Paul SM, Olney JW, Sanes JR, Holtzman DM. 2003. PDAPP; YFP double transgenic mice: a tool to study amyloid-beta associated changes in axonal, dendritic, and synaptic structures. J Comp Neurol 456: 375-383.
-
(2003)
J Comp Neurol
, vol.456
, pp. 375-383
-
-
Brendza, R.P.1
O'Brien, C.2
Simmons, K.3
McKeel, D.W.4
Bales, K.R.5
Paul, S.M.6
Olney, J.W.7
Sanes, J.R.8
Holtzman, D.M.9
-
10
-
-
85047691873
-
Anti-Abeta antibody treatment promotes the rapid recovery of amyloid-associated neuritic dystrophy in PDAPP transgenic mice
-
Brendza RP, Bacskai BJ, Cirrito JR, Simmons KA, Skoch JM, Klunk WE, Mathis CA, Bales KR, Paul SM, Hyman BT, Holtzman DM. 2005. Anti-Abeta antibody treatment promotes the rapid recovery of amyloid-associated neuritic dystrophy in PDAPP transgenic mice. J Clin Invest 115: 428-433.
-
(2005)
J Clin Invest
, vol.115
, pp. 428-433
-
-
Brendza, R.P.1
Bacskai, B.J.2
Cirrito, J.R.3
Simmons, K.A.4
Skoch, J.M.5
Klunk, W.E.6
Mathis, C.A.7
Bales, K.R.8
Paul, S.M.9
Hyman, B.T.10
Holtzman, D.M.11
-
11
-
-
79954449798
-
In vivo multiphoton imaging reveals gradual growth of newborn amyloid plaques over weeks
-
Burgold S, Bittner T, Dorostkar MM, Kieser D, Fuhrmann M, Mitteregger G, Kretzschmar H, Schmidt B, Herms J. 2011. In vivo multiphoton imaging reveals gradual growth of newborn amyloid plaques over weeks. Acta Neuropathol 121: 327-335.
-
(2011)
Acta Neuropathol
, vol.121
, pp. 327-335
-
-
Burgold, S.1
Bittner, T.2
Dorostkar, M.M.3
Kieser, D.4
Fuhrmann, M.5
Mitteregger, G.6
Kretzschmar, H.7
Schmidt, B.8
Herms, J.9
-
12
-
-
0036774951
-
Axon pathology in neurological disease: a neglected therapeutic target
-
Coleman MP, Perry VH. 2002. Axon pathology in neurological disease: a neglected therapeutic target. Trends Neurosci 25: 532-537.
-
(2002)
Trends Neurosci
, vol.25
, pp. 532-537
-
-
Coleman, M.P.1
Perry, V.H.2
-
13
-
-
72949094212
-
Genetic reductions of beta-site amyloid precursor protein-cleaving enzyme 1 and amyloid-beta ameliorate impairment of conditioned taste aversion memory in 5XFAD Alzheimer's disease model mice
-
Devi L, Ohno M. 2010. Genetic reductions of beta-site amyloid precursor protein-cleaving enzyme 1 and amyloid-beta ameliorate impairment of conditioned taste aversion memory in 5XFAD Alzheimer's disease model mice. Eur J Neurosci 31: 110-118.
-
(2010)
Eur J Neurosci
, vol.31
, pp. 110-118
-
-
Devi, L.1
Ohno, M.2
-
14
-
-
81955164821
-
Mitochondrial dysfunction and accumulation of the beta-secretase-cleaved C-terminal fragment of APP in Alzheimer's disease transgenic mice
-
Devi L, Ohno M. 2012. Mitochondrial dysfunction and accumulation of the beta-secretase-cleaved C-terminal fragment of APP in Alzheimer's disease transgenic mice. Neurobiol Dis 45: 417-424.
-
(2012)
Neurobiol Dis
, vol.45
, pp. 417-424
-
-
Devi, L.1
Ohno, M.2
-
15
-
-
36949016215
-
Alzheimer disease models and human neuropathology: similarities and differences
-
Duyckaerts C, Potier MC, Delatour B. 2008. Alzheimer disease models and human neuropathology: similarities and differences. Acta Neuropathol 115: 5-38.
-
(2008)
Acta Neuropathol
, vol.115
, pp. 5-38
-
-
Duyckaerts, C.1
Potier, M.C.2
Delatour, B.3
-
16
-
-
79955077780
-
Two-photon microscopy for chemical neuroscience
-
Ellis-Davies GC. 2011. Two-photon microscopy for chemical neuroscience. ACS Chem Neurosci 2: 185-197.
-
(2011)
ACS Chem Neurosci
, vol.2
, pp. 185-197
-
-
Ellis-Davies, G.C.1
-
17
-
-
0033634813
-
Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP
-
Feng G, Mellor RH, Bernstein M, Keller-Peck C, Nguyen QT, Wallace M, Nerbonne JM, Lichtman JW, Sanes JR. 2000. Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP. Neuron 28: 41-51.
-
(2000)
Neuron
, vol.28
, pp. 41-51
-
-
Feng, G.1
Mellor, R.H.2
Bernstein, M.3
Keller-Peck, C.4
Nguyen, Q.T.5
Wallace, M.6
Nerbonne, J.M.7
Lichtman, J.W.8
Sanes, J.R.9
-
18
-
-
84869097232
-
Quantitative longitudinal interrelationships between brain metabolism and amyloid deposition during a 2-year follow-up in patients with early Alzheimer's disease
-
Forster S, Yousefi BH, Wester HJ, Klupp E, Rominger A, Forstl H, Kurz A, Grimmer T, Drzezga A. 2012. Quantitative longitudinal interrelationships between brain metabolism and amyloid deposition during a 2-year follow-up in patients with early Alzheimer's disease. Eur J Nucl Med Mol Imaging 39: 1927-1936.
-
(2012)
Eur J Nucl Med Mol Imaging
, vol.39
, pp. 1927-1936
-
-
Forster, S.1
Yousefi, B.H.2
Wester, H.J.3
Klupp, E.4
Rominger, A.5
Forstl, H.6
Kurz, A.7
Grimmer, T.8
Drzezga, A.9
-
19
-
-
65349171063
-
Pathological substrates of cognitive decline in Alzheimer's disease
-
Giannakopoulos P, Kovari E, Gold G, von Gunten A, Hof PR, Bouras C. 2009. Pathological substrates of cognitive decline in Alzheimer's disease. Front Neurol Neurosci 24: 20-29.
-
(2009)
Front Neurol Neurosci
, vol.24
, pp. 20-29
-
-
Giannakopoulos, P.1
Kovari, E.2
Gold, G.3
von Gunten, A.4
Hof, P.R.5
Bouras, C.6
-
20
-
-
0037180796
-
Long-term dendritic spine stability in the adult cortex
-
Grutzendler J, Kasthuri N, Gan WB. 2002. Long-term dendritic spine stability in the adult cortex. Nature 420: 812-816.
-
(2002)
Nature
, vol.420
, pp. 812-816
-
-
Grutzendler, J.1
Kasthuri, N.2
Gan, W.B.3
-
21
-
-
78651476133
-
Long-term in vivo imaging of beta-amyloid plaque appearance and growth in a mouse model of cerebral beta-amyloidosis
-
Hefendehl JK, Wegenast-Braun BM, Liebig C, Eicke D, Milford D, Calhoun ME, Kohsaka S, Eichner M, Jucker M. 2011. Long-term in vivo imaging of beta-amyloid plaque appearance and growth in a mouse model of cerebral beta-amyloidosis. J Neurosci 31: 624-629.
-
(2011)
J Neurosci
, vol.31
, pp. 624-629
-
-
Hefendehl, J.K.1
Wegenast-Braun, B.M.2
Liebig, C.3
Eicke, D.4
Milford, D.5
Calhoun, M.E.6
Kohsaka, S.7
Eichner, M.8
Jucker, M.9
-
22
-
-
69249100460
-
Experience-dependent structural synaptic plasticity in the mammalian brain
-
Holtmaat A, Svoboda K. 2009. Experience-dependent structural synaptic plasticity in the mammalian brain. Nat Rev Neurosci 10: 647-658.
-
(2009)
Nat Rev Neurosci
, vol.10
, pp. 647-658
-
-
Holtmaat, A.1
Svoboda, K.2
-
23
-
-
12344250057
-
Transient and persistent dendritic spines in the neocortex in vivo
-
Holtmaat AJ, Trachtenberg JT, Wilbrecht L, Shepherd GM, Zhang X, Knott GW, Svoboda K. 2005. Transient and persistent dendritic spines in the neocortex in vivo. Neuron 45: 279-291.
-
(2005)
Neuron
, vol.45
, pp. 279-291
-
-
Holtmaat, A.J.1
Trachtenberg, J.T.2
Wilbrecht, L.3
Shepherd, G.M.4
Zhang, X.5
Knott, G.W.6
Svoboda, K.7
-
24
-
-
33745562839
-
Experience-dependent and cell-type-specific spine growth in the neocortex
-
Holtmaat A, Wilbrecht L, Knott GW, Welker E, Svoboda K. 2006. Experience-dependent and cell-type-specific spine growth in the neocortex. Nature 441: 979-983.
-
(2006)
Nature
, vol.441
, pp. 979-983
-
-
Holtmaat, A.1
Wilbrecht, L.2
Knott, G.W.3
Welker, E.4
Svoboda, K.5
-
25
-
-
67651013632
-
Long-term, high-resolution imaging in the mouse neocortex through a chronic cranial window
-
Holtmaat A, Bonhoeffer T, Chow DK, Chuckowree J, De Paola V, Hofer SB, Hubener M, Keck T, Knott G, Lee WC, Mostany R, Mrsic-Flogel TD, Nedivi E, Portera-Cailliau C, Svoboda K, Trachtenberg JT, Wilbrecht L. 2009. Long-term, high-resolution imaging in the mouse neocortex through a chronic cranial window. Nat Protoc 4: 1128-1144.
-
(2009)
Nat Protoc
, vol.4
, pp. 1128-1144
-
-
Holtmaat, A.1
Bonhoeffer, T.2
Chow, D.K.3
Chuckowree, J.4
De Paola, V.5
Hofer, S.B.6
Hubener, M.7
Keck, T.8
Knott, G.9
Lee, W.C.10
Mostany, R.11
Mrsic-Flogel, T.D.12
Nedivi, E.13
Portera-Cailliau, C.14
Svoboda, K.15
Trachtenberg, J.T.16
Wilbrecht, L.17
-
27
-
-
77958528927
-
Motor deficits, neuron loss, and reduced anxiety coinciding with axonal degeneration and intraneuronal Abeta aggregation in the 5XFAD mouse model of Alzheimer's disease
-
Jawhar S, Trawicka A, Jenneckens C, Bayer TA, Wirths O. 2010. Motor deficits, neuron loss, and reduced anxiety coinciding with axonal degeneration and intraneuronal Abeta aggregation in the 5XFAD mouse model of Alzheimer's disease. Neurobiol Aging 33: 196.e29-40.
-
(2010)
Neurobiol Aging
, vol.33
-
-
Jawhar, S.1
Trawicka, A.2
Jenneckens, C.3
Bayer, T.A.4
Wirths, O.5
-
28
-
-
81355135439
-
Dynamic changes in PET amyloid and FDG imaging at different stages of Alzheimer's disease
-
e191
-
Kadir A, Almkvist O, Forsberg A, Wall A, Engler H, Langstrom B, Nordberg A. 2012. Dynamic changes in PET amyloid and FDG imaging at different stages of Alzheimer's disease. Neurobiol Aging 33: 198 e191-114.
-
(2012)
Neurobiol Aging
, vol.33
, pp. 198-114
-
-
Kadir, A.1
Almkvist, O.2
Forsberg, A.3
Wall, A.4
Engler, H.5
Langstrom, B.6
Nordberg, A.7
-
29
-
-
58149479368
-
Impairments in remote memory stabilization precede hippocampal synaptic and cognitive failures in 5XFAD Alzheimer mouse model
-
Kimura R, Ohno M. 2009. Impairments in remote memory stabilization precede hippocampal synaptic and cognitive failures in 5XFAD Alzheimer mouse model. Neurobiol Dis 33: 229-235.
-
(2009)
Neurobiol Dis
, vol.33
, pp. 229-235
-
-
Kimura, R.1
Ohno, M.2
-
30
-
-
77749289454
-
Partial reduction of BACE1 improves synaptic plasticity, recent and remote memories in Alzheimer's disease transgenic mice
-
Kimura R, Devi L, Ohno M. 2010. Partial reduction of BACE1 improves synaptic plasticity, recent and remote memories in Alzheimer's disease transgenic mice. J Neurochem 113: 248-261.
-
(2010)
J Neurochem
, vol.113
, pp. 248-261
-
-
Kimura, R.1
Devi, L.2
Ohno, M.3
-
31
-
-
0036707494
-
Imaging Abeta plaques in living transgenic mice with multiphoton microscopy and methoxy-X04, a systemically administered Congo red derivative
-
Klunk WE, Bacskai BJ, Mathis CA, Kajdasz ST, McLellan ME, Frosch MP, Debnath ML, Holt DP, Wang Y, Hyman BT. 2002. Imaging Abeta plaques in living transgenic mice with multiphoton microscopy and methoxy-X04, a systemically administered Congo red derivative. J Neuropathol Exp Neurol 61: 797-805.
-
(2002)
J Neuropathol Exp Neurol
, vol.61
, pp. 797-805
-
-
Klunk, W.E.1
Bacskai, B.J.2
Mathis, C.A.3
Kajdasz, S.T.4
McLellan, M.E.5
Frosch, M.P.6
Debnath, M.L.7
Holt, D.P.8
Wang, Y.9
Hyman, B.T.10
-
32
-
-
50349083093
-
Dendritic spine loss and synaptic alterations in Alzheimer's disease
-
Knobloch M, Mansuy IM. 2008. Dendritic spine loss and synaptic alterations in Alzheimer's disease. Mol Neurobiol 37: 73-82.
-
(2008)
Mol Neurobiol
, vol.37
, pp. 73-82
-
-
Knobloch, M.1
Mansuy, I.M.2
-
33
-
-
84857794142
-
Opposite effects of fear conditioning and extinction on dendritic spine remodelling
-
Lai CS, Franke TF, Gan WB. 2012. Opposite effects of fear conditioning and extinction on dendritic spine remodelling. Nature 483: 87-91.
-
(2012)
Nature
, vol.483
, pp. 87-91
-
-
Lai, C.S.1
Franke, T.F.2
Gan, W.B.3
-
34
-
-
11544279355
-
Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins
-
Lambert MP, Barlow AK, Chromy BA, Edwards C, Freed R, Liosatos M, Morgan TE, Rozovsky I, Trommer B, Viola KL, Wals P, Zhang C, Finch CE, Krafft GA, Klein WL. 1998. Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins. Proc Natl Acad Sci U S A 95: 6448-6453.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 6448-6453
-
-
Lambert, M.P.1
Barlow, A.K.2
Chromy, B.A.3
Edwards, C.4
Freed, R.5
Liosatos, M.6
Morgan, T.E.7
Rozovsky, I.8
Trommer, B.9
Viola, K.L.10
Wals, P.11
Zhang, C.12
Finch, C.E.13
Krafft, G.A.14
Klein, W.L.15
-
36
-
-
58149394415
-
Amyloid pathology is associated with progressive monoaminergic neurodegeneration in a transgenic mouse model of Alzheimer's disease
-
Liu Y, Yoo MJ, Savonenko A, Stirling W, Price DL, Borchelt DR, Mamounas L, Lyons WE, Blue ME, Lee MK. 2008. Amyloid pathology is associated with progressive monoaminergic neurodegeneration in a transgenic mouse model of Alzheimer's disease. J Neurosci 28: 13805-13814.
-
(2008)
J Neurosci
, vol.28
, pp. 13805-13814
-
-
Liu, Y.1
Yoo, M.J.2
Savonenko, A.3
Stirling, W.4
Price, D.L.5
Borchelt, D.R.6
Mamounas, L.7
Lyons, W.E.8
Blue, M.E.9
Lee, M.K.10
-
37
-
-
77950458272
-
Dendritic vulnerability in neurodegenerative disease: insights from analyses of cortical pyramidal neurons in transgenic mouse models
-
Luebke JI, Weaver CM, Rocher AB, Rodriguez A, Crimins JL, Dickstein DL, Wearne SL, Hof PR. 2010. Dendritic vulnerability in neurodegenerative disease: insights from analyses of cortical pyramidal neurons in transgenic mouse models. Brain Struct Funct 214: 181-199.
-
(2010)
Brain Struct Funct
, vol.214
, pp. 181-199
-
-
Luebke, J.I.1
Weaver, C.M.2
Rocher, A.B.3
Rodriguez, A.4
Crimins, J.L.5
Dickstein, D.L.6
Wearne, S.L.7
Hof, P.R.8
-
38
-
-
80052419764
-
Layer-specific alterations to CA1 dendritic spines in a mouse model of Alzheimer's disease
-
Merino-Serrais P, Knafo S, Alonso-Nanclares L, Fernaud-Espinosa I, DeFelipe J. 2011. Layer-specific alterations to CA1 dendritic spines in a mouse model of Alzheimer's disease. Hippocampus 21: 1037-1044.
-
(2011)
Hippocampus
, vol.21
, pp. 1037-1044
-
-
Merino-Serrais, P.1
Knafo, S.2
Alonso-Nanclares, L.3
Fernaud-Espinosa, I.4
DeFelipe, J.5
-
39
-
-
38949123792
-
Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease
-
Meyer-Luehmann M, Spires-Jones TL, Prada C, Garcia-Alloza M, de Calignon A, Rozkalne A, Koenigsknecht-Talboo J, Holtzman DM, Bacskai BJ, Hyman BT. 2008. Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease. Nature 451: 720-724.
-
(2008)
Nature
, vol.451
, pp. 720-724
-
-
Meyer-Luehmann, M.1
Spires-Jones, T.L.2
Prada, C.3
Garcia-Alloza, M.4
de Calignon, A.5
Rozkalne, A.6
Koenigsknecht-Talboo, J.7
Holtzman, D.M.8
Bacskai, B.J.9
Hyman, B.T.10
-
40
-
-
0035168927
-
Pathologic correlates of nondemented aging, mild cognitive impairment, and early-stage Alzheimer's disease
-
Morris JC, Price JL. 2001. Pathologic correlates of nondemented aging, mild cognitive impairment, and early-stage Alzheimer's disease. J Mol Neurosci 17: 101-118.
-
(2001)
J Mol Neurosci
, vol.17
, pp. 101-118
-
-
Morris, J.C.1
Price, J.L.2
-
41
-
-
34047196475
-
Life and death of neurons in the aging cerebral cortex
-
Morrison JH, Hof PR. 2007. Life and death of neurons in the aging cerebral cortex. Int Rev Neurobiol 81: 41-57.
-
(2007)
Int Rev Neurobiol
, vol.81
, pp. 41-57
-
-
Morrison, J.H.1
Hof, P.R.2
-
42
-
-
79955944729
-
In vivo two-photon uncaging of glutamate revealing the structure-function relationships of dendritic spines in the neocortex of adult mice
-
Noguchi J, Nagaoka A, Watanabe S, Ellis-Davies GC, Kitamura K, Kano M, Matsuzaki M, Kasai H. 2011. In vivo two-photon uncaging of glutamate revealing the structure-function relationships of dendritic spines in the neocortex of adult mice. J Physiol 589: 2447-2457.
-
(2011)
J Physiol
, vol.589
, pp. 2447-2457
-
-
Noguchi, J.1
Nagaoka, A.2
Watanabe, S.3
Ellis-Davies, G.C.4
Kitamura, K.5
Kano, M.6
Matsuzaki, M.7
Kasai, H.8
-
43
-
-
33749521100
-
Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation
-
Oakley H, Cole SL, Logan S, Maus E, Shao P, Craft J, Guillozet-Bongaarts A, Ohno M, Disterhoft J, Van Eldik L, Berry R, Vassar R. 2006. Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation. J Neurosci 26: 10129-10140.
-
(2006)
J Neurosci
, vol.26
, pp. 10129-10140
-
-
Oakley, H.1
Cole, S.L.2
Logan, S.3
Maus, E.4
Shao, P.5
Craft, J.6
Guillozet-Bongaarts, A.7
Ohno, M.8
Disterhoft, J.9
Van Eldik, L.10
Berry, R.11
Vassar, R.12
-
44
-
-
33947247360
-
BACE1 gene deletion prevents neuron loss and memory deficits in 5XFAD APP/PS1 transgenic mice
-
Ohno M, Cole SL, Yasvoina M, Zhao J, Citron M, Berry R, Disterhoft JF, Vassar R. 2007. BACE1 gene deletion prevents neuron loss and memory deficits in 5XFAD APP/PS1 transgenic mice. Neurobiol Dis 26: 134-145.
-
(2007)
Neurobiol Dis
, vol.26
, pp. 134-145
-
-
Ohno, M.1
Cole, S.L.2
Yasvoina, M.3
Zhao, J.4
Citron, M.5
Berry, R.6
Disterhoft, J.F.7
Vassar, R.8
-
45
-
-
84862646168
-
18F]FDG PET
-
18F]FDG PET. Eur J Nucl Med Mol Imaging 39: 990-1000.
-
(2012)
Eur J Nucl Med Mol Imaging
, vol.39
, pp. 990-1000
-
-
Ossenkoppele, R.1
Tolboom, N.2
Foster-Dingley, J.C.3
Adriaanse, S.F.4
Boellaard, R.5
Yaqub, M.6
Windhorst, A.D.7
Barkhof, F.8
Lammertsma, A.A.9
Scheltens, P.10
van der Flier, W.M.11
van Berckel, B.N.12
-
46
-
-
42949114871
-
Two-photon imaging of dendritic spine development in the mouse cortex
-
Pan F, Gan WB. 2008. Two-photon imaging of dendritic spine development in the mouse cortex. Dev Neurobiol 68: 771-778.
-
(2008)
Dev Neurobiol
, vol.68
, pp. 771-778
-
-
Pan, F.1
Gan, W.B.2
-
47
-
-
51349156675
-
Amyloid plaque and neurofibrillary tangle pathology in a regulatable mouse model of Alzheimer's disease
-
Paulson JB, Ramsden M, Forster C, Sherman MA, McGowan E, Ashe KH. 2008. Amyloid plaque and neurofibrillary tangle pathology in a regulatable mouse model of Alzheimer's disease. Am J Pathol 173: 762-772.
-
(2008)
Am J Pathol
, vol.173
, pp. 762-772
-
-
Paulson, J.B.1
Ramsden, M.2
Forster, C.3
Sherman, M.A.4
McGowan, E.5
Ashe, K.H.6
-
48
-
-
0032989712
-
Tangles and plaques in nondemented aging and "preclinical" Alzheimer's disease
-
Price JL, Morris JC. 1999. Tangles and plaques in nondemented aging and "preclinical" Alzheimer's disease. Ann Neurol 45: 358-368.
-
(1999)
Ann Neurol
, vol.45
, pp. 358-368
-
-
Price, J.L.1
Morris, J.C.2
-
49
-
-
0034849725
-
Neuron number in the entorhinal cortex and CA1 in preclinical Alzheimer disease
-
Price JL, Ko AI, Wade MJ, Tsou SK, McKeel DW, Morris JC. 2001. Neuron number in the entorhinal cortex and CA1 in preclinical Alzheimer disease. Arch Neurol 58: 1395-1402.
-
(2001)
Arch Neurol
, vol.58
, pp. 1395-1402
-
-
Price, J.L.1
Ko, A.I.2
Wade, M.J.3
Tsou, S.K.4
McKeel, D.W.5
Morris, J.C.6
-
50
-
-
44349154735
-
Automated three-dimensional detection and shape classification of dendritic spines from fluorescence microscopy images
-
Rodriguez A, Ehlenberger DB, Dickstein DL, Hof PR, Wearne SL. 2008. Automated three-dimensional detection and shape classification of dendritic spines from fluorescence microscopy images. PLoS One 3: e1997.
-
(2008)
PLoS One
, vol.3
-
-
Rodriguez, A.1
Ehlenberger, D.B.2
Dickstein, D.L.3
Hof, P.R.4
Wearne, S.L.5
-
51
-
-
33947314641
-
Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway
-
Shankar GM, Bloodgood BL, Townsend M, Walsh DM, Selkoe DJ, Sabatini BL. 2007. Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway. J Neurosci 27: 2866-2875.
-
(2007)
J Neurosci
, vol.27
, pp. 2866-2875
-
-
Shankar, G.M.1
Bloodgood, B.L.2
Townsend, M.3
Walsh, D.M.4
Selkoe, D.J.5
Sabatini, B.L.6
-
52
-
-
33750711451
-
Amyloid beta peptide adversely affects spine number and motility in hippocampal neurons
-
Shrestha BR, Vitolo OV, Joshi P, Lordkipanidze T, Shelanski M, Dunaevsky A. 2006. Amyloid beta peptide adversely affects spine number and motility in hippocampal neurons. Mol Cell Neurosci 33: 274-282.
-
(2006)
Mol Cell Neurosci
, vol.33
, pp. 274-282
-
-
Shrestha, B.R.1
Vitolo, O.V.2
Joshi, P.3
Lordkipanidze, T.4
Shelanski, M.5
Dunaevsky, A.6
-
53
-
-
23044445669
-
Regulation of NMDA receptor trafficking by amyloid-beta
-
Snyder EM, Nong Y, Almeida CG, Paul S, Moran T, Choi EY, Nairn AC, Salter MW, Lombroso PJ, Gouras GK, Greengard P. 2005. Regulation of NMDA receptor trafficking by amyloid-beta. Nat Neurosci 8: 1051-1058.
-
(2005)
Nat Neurosci
, vol.8
, pp. 1051-1058
-
-
Snyder, E.M.1
Nong, Y.2
Almeida, C.G.3
Paul, S.4
Moran, T.5
Choi, E.Y.6
Nairn, A.C.7
Salter, M.W.8
Lombroso, P.J.9
Gouras, G.K.10
Greengard, P.11
-
54
-
-
2942620844
-
Dendritic spine pathology and deficits in experience-dependent dendritic plasticity in R6/1 Huntington's disease transgenic mice
-
Spires TL, Grote HE, Garry S, Cordery PM, Van Dellen A, Blakemore C, Hannan AJ. 2004. Dendritic spine pathology and deficits in experience-dependent dendritic plasticity in R6/1 Huntington's disease transgenic mice. Eur J Neurosci 19: 2799-2807.
-
(2004)
Eur J Neurosci
, vol.19
, pp. 2799-2807
-
-
Spires, T.L.1
Grote, H.E.2
Garry, S.3
Cordery, P.M.4
Van Dellen, A.5
Blakemore, C.6
Hannan, A.J.7
-
55
-
-
23444448170
-
Dendritic spine abnormalities in amyloid precursor protein transgenic mice demonstrated by gene transfer and intravital multiphoton microscopy
-
Spires TL, Meyer-Luehmann M, Stern EA, McLean PJ, Skoch J, Nguyen PT, Bacskai BJ, Hyman BT. 2005. Dendritic spine abnormalities in amyloid precursor protein transgenic mice demonstrated by gene transfer and intravital multiphoton microscopy. J Neurosci 25: 7278-7287.
-
(2005)
J Neurosci
, vol.25
, pp. 7278-7287
-
-
Spires, T.L.1
Meyer-Luehmann, M.2
Stern, E.A.3
McLean, P.J.4
Skoch, J.5
Nguyen, P.T.6
Bacskai, B.J.7
Hyman, B.T.8
-
56
-
-
0037180832
-
Long-term in vivo imaging of experience-dependent synaptic plasticity in adult cortex
-
Trachtenberg JT, Chen BE, Knott GW, Feng G, Sanes JR, Welker E, Svoboda K. 2002. Long-term in vivo imaging of experience-dependent synaptic plasticity in adult cortex. Nature 420: 788-794.
-
(2002)
Nature
, vol.420
, pp. 788-794
-
-
Trachtenberg, J.T.1
Chen, B.E.2
Knott, G.W.3
Feng, G.4
Sanes, J.R.5
Welker, E.6
Svoboda, K.7
-
57
-
-
7044220336
-
Fibrillar amyloid deposition leads to local synaptic abnormalities and breakage of neuronal branches
-
Tsai J, Grutzendler J, Duff K, Gan WB. 2004. Fibrillar amyloid deposition leads to local synaptic abnormalities and breakage of neuronal branches. Nat Neurosci 7: 1181-1183.
-
(2004)
Nat Neurosci
, vol.7
, pp. 1181-1183
-
-
Tsai, J.1
Grutzendler, J.2
Duff, K.3
Gan, W.B.4
-
58
-
-
0036968626
-
Sporadic amyotrophic lateral sclerosis with circumscribed temporal atrophy: a report of an autopsy case without dementia and with ubiquitinated intraneuronal inclusions
-
Tsuchiya K, Takahashi M, Shiotsu H, Akiyama H, Haga C, Watabiki S, Taki K, Nakano I, Ikeda K. 2002. Sporadic amyotrophic lateral sclerosis with circumscribed temporal atrophy: a report of an autopsy case without dementia and with ubiquitinated intraneuronal inclusions. Neuropathology 22: 308-316.
-
(2002)
Neuropathology
, vol.22
, pp. 308-316
-
-
Tsuchiya, K.1
Takahashi, M.2
Shiotsu, H.3
Akiyama, H.4
Haga, C.5
Watabiki, S.6
Taki, K.7
Nakano, I.8
Ikeda, K.9
-
59
-
-
0033595706
-
Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE
-
Vassar R, Bennett BD, Babu-Khan S, Kahn S, Mendiaz EA, Denis P, Teplow DB, Ross S, Amarante P, Loeloff R, Luo Y, Fisher S, Fuller J, Edenson S, Lile J, Jarosinski MA, Biere AL, Curran E, Burgess T, Louis JC, Collins F, Treanor J, Rogers G, Citron M. 1999. Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE. Science 286: 735-741.
-
(1999)
Science
, vol.286
, pp. 735-741
-
-
Vassar, R.1
Bennett, B.D.2
Babu-Khan, S.3
Kahn, S.4
Mendiaz, E.A.5
Denis, P.6
Teplow, D.B.7
Ross, S.8
Amarante, P.9
Loeloff, R.10
Luo, Y.11
Fisher, S.12
Fuller, J.13
Edenson, S.14
Lile, J.15
Jarosinski, M.A.16
Biere, A.L.17
Curran, E.18
Burgess, T.19
Louis, J.C.20
Collins, F.21
Treanor, J.22
Rogers, G.23
Citron, M.24
more..
-
60
-
-
28844498390
-
New techniques for imaging, digitization and analysis of three-dimensional neural morphology on multiple scales
-
Wearne SL, Rodriguez A, Ehlenberger DB, Rocher AB, Henderson SC, Hof PR. 2005. New techniques for imaging, digitization and analysis of three-dimensional neural morphology on multiple scales. Neuroscience 136: 661-680.
-
(2005)
Neuroscience
, vol.136
, pp. 661-680
-
-
Wearne, S.L.1
Rodriguez, A.2
Ehlenberger, D.B.3
Rocher, A.B.4
Henderson, S.C.5
Hof, P.R.6
-
61
-
-
69449102408
-
Characterizing the appearance and growth of amyloid plaques in APP/PS1 mice
-
Yan P, Bero AW, Cirrito JR, Xiao Q, Hu X, Wang Y, Gonzales E, Holtzman DM, Lee JM. 2009. Characterizing the appearance and growth of amyloid plaques in APP/PS1 mice. J Neurosci 29: 10706-10714.
-
(2009)
J Neurosci
, vol.29
, pp. 10706-10714
-
-
Yan, P.1
Bero, A.W.2
Cirrito, J.R.3
Xiao, Q.4
Hu, X.5
Wang, Y.6
Gonzales, E.7
Holtzman, D.M.8
Lee, J.M.9
-
62
-
-
0034618715
-
Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing
-
Yu G, Nishimura M, Arawaka S, Levitan D, Zhang L, Tandon A, Song YQ, Rogaeva E, Chen F, Kawarai T, Supala A, Levesque L, Yu H, Yang DS, Holmes E, Milman P, Liang Y, Zhang DM, Xu DH, Sato C, Rogaev E, Smith M, Janus C, Zhang Y, Aebersold R, Farrer LS, Sorbi S, Bruni A, Fraser P, St George-Hyslop P. 2000. Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing. Nature 407: 48-54.
-
(2000)
Nature
, vol.407
, pp. 48-54
-
-
Yu, G.1
Nishimura, M.2
Arawaka, S.3
Levitan, D.4
Zhang, L.5
Tandon, A.6
Song, Y.Q.7
Rogaeva, E.8
Chen, F.9
Kawarai, T.10
Supala, A.11
Levesque, L.12
Yu, H.13
Yang, D.S.14
Holmes, E.15
Milman, P.16
Liang, Y.17
Zhang, D.M.18
Xu, D.H.19
Sato, C.20
Rogaev, E.21
Smith, M.22
Janus, C.23
Zhang, Y.24
Aebersold, R.25
Farrer, L.S.26
Sorbi, S.27
Bruni, A.28
Fraser, P.29
St George-Hyslop, P.30
more..
-
63
-
-
78449300244
-
Thiamine deficiency increases beta-secretase activity and accumulation of beta-amyloid peptides
-
Zhang Q, Yang G, Li W, Fan Z, Sun A, Luo J, Ke ZJ. 2011. Thiamine deficiency increases beta-secretase activity and accumulation of beta-amyloid peptides. Neurobiol Aging 32: 42-53.
-
(2011)
Neurobiol Aging
, vol.32
, pp. 42-53
-
-
Zhang, Q.1
Yang, G.2
Li, W.3
Fan, Z.4
Sun, A.5
Luo, J.6
Ke, Z.J.7
-
64
-
-
72949089907
-
Beta-secretase-1 elevation in transgenic mouse models of Alzheimer's disease is associated with synaptic/axonal pathology and amyloidogenesis: implications for neuritic plaque development
-
Zhang XM, Cai Y, Xiong K, Cai H, Luo XG, Feng JC, Clough RW, Struble RG, Patrylo PR, Yan XX. 2009. Beta-secretase-1 elevation in transgenic mouse models of Alzheimer's disease is associated with synaptic/axonal pathology and amyloidogenesis: implications for neuritic plaque development. Eur J Neurosci 30: 2271-2283.
-
(2009)
Eur J Neurosci
, vol.30
, pp. 2271-2283
-
-
Zhang, X.M.1
Cai, Y.2
Xiong, K.3
Cai, H.4
Luo, X.G.5
Feng, J.C.6
Clough, R.W.7
Struble, R.G.8
Patrylo, P.R.9
Yan, X.X.10
-
65
-
-
34147120073
-
Beta-site amyloid precursor protein cleaving enzyme 1 levels become elevated in neurons around amyloid plaques: implications for Alzheimer's disease pathogenesis
-
Zhao J, Fu Y, Yasvoina M, Shao P, Hitt B, O'Connor T, Logan S, Maus E, Citron M, Berry R, Binder L, Vassar R. 2007. Beta-site amyloid precursor protein cleaving enzyme 1 levels become elevated in neurons around amyloid plaques: implications for Alzheimer's disease pathogenesis. J Neurosci 27: 3639-3649.
-
(2007)
J Neurosci
, vol.27
, pp. 3639-3649
-
-
Zhao, J.1
Fu, Y.2
Yasvoina, M.3
Shao, P.4
Hitt, B.5
O'Connor, T.6
Logan, S.7
Maus, E.8
Citron, M.9
Berry, R.10
Binder, L.11
Vassar, R.12
-
66
-
-
22444441508
-
Long-term sensory deprivation prevents dendritic spine loss in primary somatosensory cortex
-
Zuo Y, Yang G, Kwon E, Gan WB. 2005. Long-term sensory deprivation prevents dendritic spine loss in primary somatosensory cortex. Nature 436: 261-265.
-
(2005)
Nature
, vol.436
, pp. 261-265
-
-
Zuo, Y.1
Yang, G.2
Kwon, E.3
Gan, W.B.4
|