Mitochondrial Peroxiredoxin 3 Regulates Sensory Cell Survival in the Cochlea

PLoS ONE

Volumn 8, Issue 4, 2013, Pages

  Chen, Fu Quan ^a,c   Zheng, Hong Wei ^a   Schacht, Jochen ^b   Sha, Su Hua ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^c FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

2,3 DIHYDROXYBENZOIC ACID; GENTAMICIN; KANAMYCIN; MESSENGER RNA; MITOCHONDRIAL ENZYME; PEROXIREDOXIN 3; PHENYLENEDIAMINE; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; 2,3-DIHYDROXYBENZOIC ACID; HOMEODOMAIN PROTEIN; HYDROXYBENZOIC ACID DERIVATIVE; SCAVENGER; SHOX2 PROTEIN, MOUSE;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CELL LOSS; CELL STRESS; CELL SURVIVAL; COCHLEA; CONTROLLED STUDY; CORTI ORGAN; DISEASE PREDISPOSITION; DISEASE SEVERITY; ENZYME ACTIVITY; ENZYME REGULATION; HAIR CELL; HEARING IMPAIRMENT; IN VIVO STUDY; MALE; MOUSE; NERVE CELL NECROSIS; NOISE INJURY; NONHUMAN; OXIDATIVE STRESS; REGULATORY MECHANISM; SENSORY NERVE CELL; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; CBA MOUSE; CHEMICALLY INDUCED; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; NOISE; PATHOLOGY; PERCEPTION DEAFNESS; SEVERITY OF ILLNESS INDEX;

ANIMALS; CELL DEATH; CELL SURVIVAL; FREE RADICAL SCAVENGERS; GENE EXPRESSION REGULATION; GENTAMICINS; HAIR CELLS, AUDITORY; HEARING LOSS, SENSORINEURAL; HOMEODOMAIN PROTEINS; HYDROXYBENZOATES; KANAMYCIN; MALE; MICE; MICE, INBRED CBA; NOISE; OXIDATIVE STRESS; RNA, SMALL INTERFERING; SEVERITY OF ILLNESS INDEX;

EID: 84876566684     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0061999     Document Type: Article

References (38)

1. Chae HZ, Kim HJ, Kang SW, Rhee SG, (1999) Characterization of three isoforms of mammalian peroxiredoxin that reduce peroxides in the presence of thioredoxin. Diabetes Res Clin Pract 45: 101-12.
2. Chae HZ, Oubrahim H, Park JW, Rhee SG, Chock PB, (2012) Protein glutathionylation in the regulation of peroxiredoxins: a family of thiol-specific peroxidases that function as antioxidants, molecular chaperones, and signal modulators. Antioxid Redox Signal 16: 506-23.
3. Wonsey DR, Zeller KI, Dang CV, (2002) The c-Myc target gene PRDX3 is required for mitochondrial homeostasis and neoplastic transformation. Proc Natl Acad Sci U S A 99: 6649-54.
4. Hattori F, Murayama N, Noshita T, Oikawa S, (2003) Mitochondrial peroxiredoxin-3 protects hippocampal neurons from excitotoxic injury in vivo. J Neurochem 86: 860-8.
5. Matsushima S, Ide T, Yamato M, Matsusaka H, Hattori F, et al. (2006) Overexpression of mitochondrial peroxiredoxin-3 prevents left ventricular remodeling and failure after myocardial infarction in mice. Circulation 113: 1779-86.
6. Chang TS, Cho CS, Park S, Yu S, Kang SW, et al. (2004) Peroxiredoxin III, a mitochondrion-specific peroxidase, regulates apoptotic signaling by mitochondria. J Biol Chem 279: 41975-84.
7. Mukhopadhyay SS, Leung KS, Hicks MJ, Hastings PJ, Youssoufian H, et al. (2006) Defective mitochondrial peroxiredoxin-3 results in sensitivity to oxidative stress in Fanconi anemia. J Cell Biol 175: 225-35.
8. Li L, Shoji W, Takano H, Nishimura N, Aoki Y, et al. (2007) Increased susceptibility of MER5 (peroxiredoxin III) knockout mice to LPS-induced oxidative stress. Biochem Biophys Res Commun 355: 715-21.
9. Jiang H, Sha SH, Schacht J, (2005) NF-kappaB pathway protects cochlear hair cells from aminoglycoside-induced ototoxicity. J Neurosci Res 79: 644-51.
10. Jiang H, Talaska AE, Schacht J, Sha SH, (2007) Oxidative imbalance in the aging inner ear. Neurobiol Aging 28: 1605-12.
11. Yamashita D, Jiang HY, Schacht J, Miller JM, (2004) Delayed production of free radicals following noise exposure. Brain Res 1019: 201-9.
12. Forge A, Schacht J, (2000) Aminoglycoside antibiotics. Audiol Neurootol 5: 3-22.
13. Oishi N, Schacht J, (2011) Emerging treatments for noise-induced hearing loss. Expert Opin Emerg Drugs 16: 235-45.
14. Someya S, Prolla TA, (2010) Mitochondrial oxidative damage and apoptosis in age-related hearing loss. Mech Ageing Dev 131: 480-6.
15. Matt T, Ng CL, Lang K, Sha SH, Akbergenov R, et al. (2012) Dissociation of antibacterial activity and aminoglycoside ototoxicity in the 4-monosubstituted 2-deoxystreptamine apramycin. Proc Natl Acad Sci U S A 109: 10984-9.
16. Someya S, Yu W, Hallows WC, Xu J, Vann JM, et al. (2010) Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction. Cell 143: 802-12.
17. Vicente-Torres MA, Schacht J, (2006) A BAD link to mitochondrial cell death in the cochlea of mice with noise-induced hearing loss. J Neurosci Res 83: 1564-72.
18. Henderson D, Bielefeld EC, Harris KC, Hu BH, (2006) The role of oxidative stress in noise-induced hearing loss. Ear Hear 27: 1-19.
19. Sha SH, Chen FQ, Schacht J, (2009) Activation of cell death pathways in the inner ear of the aging CBA/J mouse. Hear Res 254: 92-9.
20. Chen FQ, Zheng HW, Hill K, Sha SH, (2012) Traumatic Noise Activates Rho-Family GTPases through Transient Cellular Energy Depletion. J Neurosci 32: 12421-30.
21. Sha SH, Kanicki A, Dootz G, Talaska AE, Halsey K, et al. (2008) Age-related auditory pathology in the CBA/J mouse. Hear Res 243: 87-94.
22. Wu WJ, Sha SH, McLaren JD, Kawamoto K, Raphael Y, et al. (2001) Aminoglycoside ototoxicity in adult CBA, C57BL and BALB mice and the Sprague-Dawley rat. Hear Res 158: 165-78.
23. Chen FQ, Schacht J, Sha SH, (2009) Aminoglycoside-induced histone deacetylation and hair cell death in the mouse cochlea. J Neurochem 108: 1226-36.
24. Oishi N, Chen FQ, Zheng HW, Sha SH (2012) Intra-tympanic delivery of short interfering RNA into the adult mouse cochlea. Hear Res.
25. Livak KJ, Schmittgen TD, (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-8.
26. Song BB, Anderson DJ, Schacht J, (1997) Protection from gentamicin ototoxicity by iron chelators in guinea pig in vivo. J Pharmacol Exp Ther 282: 369-77.
27. Choung YH, Taura A, Pak K, Choi SJ, Masuda M, et al. (2009) Generation of highly-reactive oxygen species is closely related to hair cell damage in rat organ of Corti treated with gentamicin. Neuroscience 161: 214-26.
28. Setsukinai K, Urano Y, Kakinuma K, Majima HJ, Nagano T, (2003) Development of novel fluorescence probes that can reliably detect reactive oxygen species and distinguish specific species. J Biol Chem 278: 3170-5.
29. Bottger EC, Schacht J (2013) The mitochondrion: A perpetrator of acquired hearing loss. Hear Res doi: 10.1016/j.heares.2013.01.006.
30. Balaban RS, Nemoto S, Finkel T, (2005) Mitochondria, oxidants, and aging. Cell 120: 483-95.
31. Menardo J, Tang Y, Ladrech S, Lenoir M, Casas F, et al. (2012) Oxidative stress, inflammation, and autophagic stress as the key mechanisms of premature age-related hearing loss in SAMP8 mouse Cochlea. Antioxid Redox Signal 16: 263-74.
32. Xie J, Talaska AE, Schacht J, (2011) New developments in aminoglycoside therapy and ototoxicity. Hear Res 281: 28-37.
33. Op de Beeck K, Schacht J, Van Camp G, (2011) Apoptosis in acquired and genetic hearing impairment: the programmed death of the hair cell. Hear Res 281: 18-27.
34. Masaki M, Ikeda A, Shiraki E, Oka S, Kawasaki T, (2003) Mixed lineage kinase LZK and antioxidant protein-1 activate NF-kappaB synergistically. Eur J Biochem 270: 76-83.
35. Lang H, Schulte BA, Zhou D, Smythe N, Spicer SS, et al. (2006) Nuclear factor kappaB deficiency is associated with auditory nerve degeneration and increased noise-induced hearing loss. J Neurosci 26: 3541-50.
36. Kopke RD, Weisskopf PA, Boone JL, Jackson RL, Wester DC, et al. (2000) Reduction of noise-induced hearing loss using L-NAC and salicylate in the chinchilla. Hear Res 149: 138-46.
37. Song BB, Sha SH, Schacht J, (1998) Iron chelators protect from aminoglycoside-induced cochleo- and vestibulo-toxicity. Free Radic Biol Med 25: 189-95.
38. Francis SP, Katz J, Fanning KD, Harris KA, Nicholas BD, et al. (2013) A novel role of cytosolic protein synthesis inhibition in aminoglycoside ototoxicity. J Neurosci 33: 3079-93.