메뉴 건너뛰기




Volumn 282, Issue 1, 1997, Pages 369-377

Protection from gentamicin ototoxicity by iron chelators in guinea pig in vivo

Author keywords

[No Author keywords available]

Indexed keywords

2,3 DIHYDROXYBENZOIC ACID; CHELATING AGENT; DEFEROXAMINE; FREE RADICAL; GENTAMICIN; MANNITOL;

EID: 0030778977     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (125)

References (40)
  • 1
    • 0029558564 scopus 로고
    • Gentamicin nephrotoxicity in humans and animals: Some recent research
    • ALI, B. H.: Gentamicin nephrotoxicity in humans and animals: some recent research. Gen. Pharmacol. 26: 1477-1487, 1995.
    • (1995) Gen. Pharmacol. , vol.26 , pp. 1477-1487
    • Ali, B.H.1
  • 3
    • 0028099826 scopus 로고
    • Influence of iron, deferoxamine and ascorbic acid on gentamicin-induced nephrotoxicity in rats
    • BEN ISMAIL, T. H., ALI, B. H. AND BASHIR, A. A.: Influence of iron, deferoxamine and ascorbic acid on gentamicin-induced nephrotoxicity in rats. Gen. Pharmacol. 25: 1249-1252, 1994.
    • (1994) Gen. Pharmacol. , vol.25 , pp. 1249-1252
    • Ben Ismail, T.H.1    Ali, B.H.2    Bashir, A.A.3
  • 4
    • 0025276120 scopus 로고
    • Comparison of deferoxamine pharmacokinetics between asymptomatic thalassemic children and those exhibiting severe neurotoxicity
    • BENTUR, Y., KOREN, G., TESORO, A., CARLEY, H., OLIVIERI, N. AND FREEDMAN, M. H.: Comparison of deferoxamine pharmacokinetics between asymptomatic thalassemic children and those exhibiting severe neurotoxicity. Clin. Pharmacol. Ther. 47: 478-482, 1990.
    • (1990) Clin. Pharmacol. Ther. , vol.47 , pp. 478-482
    • Bentur, Y.1    Koren, G.2    Tesoro, A.3    Carley, H.4    Olivieri, N.5    Freedman, M.H.6
  • 5
    • 0020674728 scopus 로고
    • Effects of N-acetylcysteine on kanamycin ototoxicity in the guinea pig
    • BOCK, G. R., YATES, G. K., MILLER, J. J. AND MOORJANI, P.: Effects of N-acetylcysteine on kanamycin ototoxicity in the guinea pig. Hear. Res. 9: 255-262, 1983.
    • (1983) Hear. Res. , vol.9 , pp. 255-262
    • Bock, G.R.1    Yates, G.K.2    Miller, J.J.3    Moorjani, P.4
  • 6
    • 0000048585 scopus 로고
    • Measurement of antibiotics in human body fluids: Techniques and significance
    • ed. by V. Lorain, Williams & Wilkins, Baltimore
    • CHAPIN-ROBERTSON, K. AND EDBERG, S. C.: Measurement of antibiotics in human body fluids: Techniques and significance. In Laboratory Medicine, 3rd ed., ed. by V. Lorain, pp. 295-304, Williams & Wilkins, Baltimore, 1991.
    • (1991) Laboratory Medicine, 3rd Ed. , pp. 295-304
    • Chapin-Robertson, K.1    Edberg, S.C.2
  • 7
    • 0006877012 scopus 로고
    • Phenolic compounds in chemotherapy of rheumatic fever
    • CLARKE, N. E., CLARKE, C. N. AND MOSHER, R. E.: Phenolic compounds in chemotherapy of rheumatic fever. Am. J. Med. Sci. 235: 7-22, 1958.
    • (1958) Am. J. Med. Sci. , vol.235 , pp. 7-22
    • Clarke, N.E.1    Clarke, C.N.2    Mosher, R.E.3
  • 9
    • 0026612118 scopus 로고
    • Formation of a toxic metabolite from gentamicin by a hepatic cytosolic fraction
    • CRANN, S. A., HUANG, M. Y., MCLAREN, J. D. AND SCHACHT, J.: Formation of a toxic metabolite from gentamicin by a hepatic cytosolic fraction. Biochem. Pharmacol. 43: 1835-1839, 1992.
    • (1992) Biochem. Pharmacol. , vol.43 , pp. 1835-1839
    • Crann, S.A.1    Huang, M.Y.2    Mclaren, J.D.3    Schacht, J.4
  • 10
    • 0030089767 scopus 로고    scopus 로고
    • Activation of aminoglycoside antibiotics to cytotoxins
    • CRANN, S. A. AND SCHACHT, J.: Activation of aminoglycoside antibiotics to cytotoxins. Audiol. Neuro-Otol. 1: 80-85, 1996.
    • (1996) Audiol. Neuro-Otol. , vol.1 , pp. 80-85
    • Crann, S.A.1    Schacht, J.2
  • 11
    • 0029063622 scopus 로고
    • Effects of gentamicin on iron and copper contents of kidney tissue
    • DURAK, J., KAVUTCU, M., CANBOLAT, O., OZTURK, S., ULUTEPE, S. AND GOKHUN, I. H.: Effects of gentamicin on iron and copper contents of kidney tissue. Nephron 70: 380-381, 1995.
    • (1995) Nephron , vol.70 , pp. 380-381
    • Durak, J.1    Kavutcu, M.2    Canbolat, O.3    Ozturk, S.4    Ulutepe, S.5    Gokhun, I.H.6
  • 12
    • 0023621784 scopus 로고
    • Serial studies of auditory neurotoxicity in patients receiving deferoxamine therapy
    • GALLANT, T., BOYDEN, M. H., GALLANT, L. A., CARLEY, H. AND FREEDMAN, M. H.: Serial studies of auditory neurotoxicity in patients receiving deferoxamine therapy. Am. J. Med. 83: 1085-1090, 1987.
    • (1987) Am. J. Med. , vol.83 , pp. 1085-1090
    • Gallant, T.1    Boyden, M.H.2    Gallant, L.A.3    Carley, H.4    Freedman, M.H.5
  • 13
    • 0028260467 scopus 로고
    • Attenuation of gentamicin ototoxicity by glutathione in the guinea pig in vivo
    • GARETZ, S. L., ALTSCHULER, R. A. AND SCHACHT, J.: Attenuation of gentamicin ototoxicity by glutathione in the guinea pig in vivo. Hear. Res. 77: 81-87, 1994a.
    • (1994) Hear. Res. , vol.77 , pp. 81-87
    • Garetz, S.L.1    Altschuler, R.A.2    Schacht, J.3
  • 14
    • 0028358176 scopus 로고
    • Sulfhydryl compounds and antioxidants inhibit cytotoxicity to outer hair cells of a gentamicin metabolite in vitro
    • GARETZ, S. L., RHEE, D. J. AND SCHACHT, J.: Sulfhydryl compounds and antioxidants inhibit cytotoxicity to outer hair cells of a gentamicin metabolite in vitro. Hear. Res. 77: 75-80, 1994b.
    • (1994) Hear. Res. , vol.77 , pp. 75-80
    • Garetz, S.L.1    Rhee, D.J.2    Schacht, J.3
  • 15
    • 0006045314 scopus 로고    scopus 로고
    • Ototoxicity: Of mice and men
    • Handbook of Auditory Research, ed. by R. R. Fay and A. N. Popper, ed. by T. R. Van De Water, A. N. Popper, and R. R. Fay, Springer, New York
    • GARETZ, S. L. AND SCHACHT, J.: Ototoxicity: Of mice and men. In Handbook of Auditory Research, ed. by R. R. Fay and A. N. Popper, Vol. VII: Clinical Aspects of Hearing, ed. by T. R. Van De Water, A. N. Popper, and R. R. Fay, pp. 116-154, Springer, New York, 1996.
    • (1996) Clinical Aspects of Hearing , vol.7 , pp. 116-154
    • Garetz, S.L.1    Schacht, J.2
  • 16
    • 0018043890 scopus 로고
    • Iron metabolism and chelation therapy in hemosiderosis
    • GRAZIANO, J. H.: Iron metabolism and chelation therapy in hemosiderosis. Curr. Topics Hematol. 1: 127-150, 1978.
    • (1978) Curr. Topics Hematol. , vol.1 , pp. 127-150
    • Graziano, J.H.1
  • 18
    • 0018582229 scopus 로고
    • Inhibition of the iron-catalysed formation of hydroxyl radiais from Superoxide and of lipid peroxidation of desferrioxamine
    • GUTTERIDGE, J. M. C., RICHMOND, R. AND HALLIWELL, B.: Inhibition of the iron-catalysed formation of hydroxyl radiais from Superoxide and of lipid peroxidation of desferrioxamine. Biochem. J. 184: 469-472, 1979.
    • (1979) Biochem. J. , vol.184 , pp. 469-472
    • Gutteridge, J.M.C.1    Richmond, R.2    Halliwell, B.3
  • 19
    • 0026466671 scopus 로고
    • Iron chelators in medicine
    • HERSHKO, C.: Iron chelators in medicine. Molec. Asp. Med. 13: 113-165, 1992.
    • (1992) Molec. Asp. Med. , vol.13 , pp. 113-165
    • Hershko, C.1
  • 20
    • 0025600829 scopus 로고
    • Formation of a cytotoxic metabolite from gentamicin by liver
    • HUANG, M. Y. AND SCHACHT, J.: Formation of a cytotoxic metabolite from gentamicin by liver. Biochem. Pharmacol. 40: R11-R14, 1990.
    • (1990) Biochem. Pharmacol. , vol.40
    • Huang, M.Y.1    Schacht, J.2
  • 21
  • 22
    • 0026336631 scopus 로고
    • Iron supplementation increases gentamicin nephrotoxicity in rats
    • KAYS, S. E., CROWELL, W. A. AND JOHNSON, M. A.: Iron supplementation increases gentamicin nephrotoxicity in rats. J. Nutr. 121: 1869-1875, 1991.
    • (1991) J. Nutr. , vol.121 , pp. 1869-1875
    • Kays, S.E.1    Crowell, W.A.2    Johnson, M.A.3
  • 23
    • 0029083057 scopus 로고
    • Glutathione protection against gentamicin ototoxicity depends on nutritional status
    • LAUTERMANN, J., MCLAREN, J. AND SCHACHT, J.: Glutathione protection against gentamicin ototoxicity depends on nutritional status. Hear. Res. 86: 15-24, 1995.
    • (1995) Hear. Res. , vol.86 , pp. 15-24
    • Lautermann, J.1    Mclaren, J.2    Schacht, J.3
  • 24
    • 0006969305 scopus 로고
    • Pharmacology of 2,3-dihydroxybenzoic acid
    • MARTINI, E. AND PONZIO, E.: Pharmacology of 2,3-dihydroxybenzoic acid. Arch. Ital. Sci. Farmacol. 2: 259-260, 1952.
    • (1952) Arch. Ital. Sci. Farmacol. , vol.2 , pp. 259-260
    • Martini, E.1    Ponzio, E.2
  • 25
    • 0021888924 scopus 로고
    • 2,3-Dihydroxybenzoic acid: Effect on mortality rate in a septic rat model
    • PEARCE, R. A., FINLEY, R. J., MUSTARD, R. A. AND DUFF, J. H.: 2,3-Dihydroxybenzoic acid: Effect on mortality rate in a septic rat model. Arch. Surg. 120: 937-940, 1985.
    • (1985) Arch. Surg. , vol.120 , pp. 937-940
    • Pearce, R.A.1    Finley, R.J.2    Mustard, R.A.3    Duff, J.H.4
  • 27
    • 0019508737 scopus 로고
    • Prophylaxis of kanamycin-induced ototoxicity by a radioprotectant
    • PIERSON, M. G. AND MØLLER, A. R.: Prophylaxis of kanamycin-induced ototoxicity by a radioprotectant. Hear. Res. 4: 79-87, 1981.
    • (1981) Hear. Res. , vol.4 , pp. 79-87
    • Pierson, M.G.1    Møller, A.R.2
  • 28
    • 0029598756 scopus 로고
    • Formation of free radicals by gentamicin and iron and evidence for an iron/gentamicin complex
    • PRIUSKA, E. M. AND SCHACHT, J.: Formation of free radicals by gentamicin and iron and evidence for an iron/gentamicin complex. Biochem. Pharmacol. 50: 1749-1752, 1995.
    • (1995) Biochem. Pharmacol. , vol.50 , pp. 1749-1752
    • Priuska, E.M.1    Schacht, J.2
  • 29
    • 0026011768 scopus 로고
    • Scar formation after drug-induced cochlear insult
    • RAPHAEL, Y. AND ALTSCHULER, R. A.: Scar formation after drug-induced cochlear insult. Hear. Res. 51: 173-184, 1991.
    • (1991) Hear. Res. , vol.51 , pp. 173-184
    • Raphael, Y.1    Altschuler, R.A.2
  • 30
    • 0016749574 scopus 로고
    • Determination of iron and unsaturated iron-binding capacity in serum with ferrozine
    • RUUTU, R.: Determination of iron and unsaturated iron-binding capacity in serum with ferrozine. Clin. Chim. Acta 61: 229-232, 1975.
    • (1975) Clin. Chim. Acta , vol.61 , pp. 229-232
    • Ruutu, R.1
  • 31
    • 0027382931 scopus 로고
    • Biochemical basis of aminoglycoside ototoxicity
    • SCHACHT, J.: Biochemical basis of aminoglycoside ototoxicity. Otolaryngol. Clin. North Am. 26: 845-856, 1993.
    • (1993) Otolaryngol. Clin. North Am. , vol.26 , pp. 845-856
    • Schacht, J.1
  • 32
    • 0008512340 scopus 로고    scopus 로고
    • Amplification of free radicals by gentamicin in a biological system
    • SHA, S.-H. AND SCHACHT, J.: Amplification of free radicals by gentamicin in a biological system (Abstract). Abs. Assoc. Res. Otolaryngol. 19: 30, 1996.
    • (1996) Abs. Assoc. Res. Otolaryngol. , vol.19 , pp. 30
    • Sha, S.-H.1    Schacht, J.2
  • 33
    • 0023621993 scopus 로고
    • The effects of deferoxamine mesylate and hypoxia on the cochlea
    • Stockh.
    • SHIRANE, M. AND HARRISON, R. V.: The effects of deferoxamine mesylate and hypoxia on the cochlea. Acta Otolaryngol. (Stockh.) 16: 334-339, 1987.
    • (1987) Acta Otolaryngol. , vol.16 , pp. 334-339
    • Shirane, M.1    Harrison, R.V.2
  • 34
    • 0030068133 scopus 로고    scopus 로고
    • Variable efficacy of radical scavengers and iron chelators to attenuate gentamicin ototoxicity in guinea pig in vivo
    • SONG, B.-B. AND SCHACHT, J.: Variable efficacy of radical scavengers and iron chelators to attenuate gentamicin ototoxicity in guinea pig in vivo. Hear. Res. 94: 87-93, 1996.
    • (1996) Hear. Res. , vol.94 , pp. 87-93
    • Song, B.-B.1    Schacht, J.2
  • 35
    • 0022381068 scopus 로고
    • Ferric iron and Superoxide ions are required for the killing of cultured hepatocytes by hydrogen peroxide: Evidence for the participation of hydroxyl radicals formed by an iron-catalyzed Haber-Weiss reaction
    • STARKE, P. E. AND FARBER, J. L.: Ferric iron and Superoxide ions are required for the killing of cultured hepatocytes by hydrogen peroxide: Evidence for the participation of hydroxyl radicals formed by an iron-catalyzed Haber-Weiss reaction. J. Biol. Chem. 260: 10099-10104, 1985.
    • (1985) J. Biol. Chem. , vol.260 , pp. 10099-10104
    • Starke, P.E.1    Farber, J.L.2
  • 37
    • 0021064028 scopus 로고
    • Synergy between the iron chelator deferoxamine and the antimicrobial agents gentamicin, chloramphenicol, cefalothin, cefotiam and cefsulodin
    • VAN ASBECK, B. S., MARCELIS, J. H., VAN KATS, J. H., JAARSMA, E. Y. AND VERHOEF, J.: Synergy between the iron chelator deferoxamine and the antimicrobial agents gentamicin, chloramphenicol, cefalothin, cefotiam and cefsulodin. Eur. J. Clin. Microbiol. 2: 432-438, 1983.
    • (1983) Eur. J. Clin. Microbiol. , vol.2 , pp. 432-438
    • Van Asbeck, B.S.1    Marcelis, J.H.2    Van Kats, J.H.3    Jaarsma, E.Y.4    Verhoef, J.5
  • 38
    • 0028219018 scopus 로고
    • Iron-chelating agents in non-iron overload conditions
    • VOEST, E. E., VREUGDENHIL, G. AND MARX, J. J.: Iron-chelating agents in non-iron overload conditions. Ann. Intern. Med. 120: 490-499, 1994.
    • (1994) Ann. Intern. Med. , vol.120 , pp. 490-499
    • Voest, E.E.1    Vreugdenhil, G.2    Marx, J.J.3
  • 39
    • 0023854331 scopus 로고
    • Evidence suggesting a role for hydroxyl radical in gentamicin-induced acute renal failure in rats
    • WALKER, P. D. AND SHAH, S. V.: Evidence suggesting a role for hydroxyl radical in gentamicin-induced acute renal failure in rats. J. Clin. Invest. 81: 334-341, 1988.
    • (1988) J. Clin. Invest. , vol.81 , pp. 334-341
    • Walker, P.D.1    Shah, S.V.2
  • 40
    • 0011803405 scopus 로고    scopus 로고
    • The iron embrace: Exposing the secret activities of gentamicin
    • WANG, H., PRIUSKA, E. M. AND SCHACHT, J.: The iron embrace: exposing the secret activities of gentamicin (Abstract). Abs. Assoc. Res. Otolaryngol. 19: 29, 1996.
    • (1996) Abs. Assoc. Res. Otolaryngol. , vol.19 , pp. 29
    • Wang, H.1    Priuska, E.M.2    Schacht, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.