Aminoglycoside-induced histone deacetylation and hair cell death in the mouse cochlea

Journal of Neurochemistry

Volumn 108, Issue 5, 2009, Pages 1226-1236

  Chen, Fu Quan ^a,b   Schacht, Jochen ^a   Sha, Su Hua ^a  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Cochlear explant; Gentamicin; Histone acetyl transferase; Histone deacetylase inhibitors; Ototoxicity

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; BUTYRIC ACID; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; GENTAMICIN; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 3; HISTONE DEACETYLASE 4; PROTEIN P300; TRICHOSTATIN A;

ACETYLATION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CBA MOUSE; CELL DEATH; CELL LOSS; COCHLEA; CONTROLLED STUDY; CORTI ORGAN; DEACETYLATION; FEMALE; HAIR CELL; HEARING; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ACETYLATION; ANIMALS; CELL COUNT; CELL DEATH; COCHLEA; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; FEMALE; GENE EXPRESSION REGULATION; GENTAMICINS; HAIR CELLS, AUDITORY; HISTONES; HYDROXAMIC ACIDS; MALE; MICE; MICE, INBRED CBA; ORGAN CULTURE TECHNIQUES; PROTEIN SYNTHESIS INHIBITORS; TIME FACTORS;

EID: 59449109623     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2009.05871.x     Document Type: Article

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