Generation of highly-reactive oxygen species is closely related to hair cell damage in rat organ of corti treated with gentamicin

Neuroscience

Volumn 161, Issue 1, 2009, Pages 214-226

  Choung, Y H ^a,b   Taura, A ^a   Pak, K ^a   Choi, S J ^b   Masuda, M ^a   Ryan, A F ^a  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b Ajou University School of Medicine   (South Korea)

Author keywords

APF; cochlea; free radical; inner ear; ototoxicity; sensory cell

Indexed keywords

GENTAMICIN; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ARTICLE; CELL DAMAGE; CELL SURVIVAL; CONTROLLED STUDY; CORTI ORGAN; DRUG EXPOSURE; HAIR CELL; IN VITRO STUDY; INTERMETHOD COMPARISON; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; SENSITIVITY ANALYSIS; STEREOCILIUM;

ANILINE COMPOUNDS; ANIMALS; ANIMALS, NEWBORN; ANTI-BACTERIAL AGENTS; FLUORESCEINS; FLUORESCENT DYES; GENTAMICINS; HAIR CELLS, AUDITORY; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES;

EID: 67349207379     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2009.02.085     Document Type: Article

References (53)

1. Aran J.M., Erre J.P., Guilhaume A., and Aurousseau C. The comparative ototoxicities of gentamicin, tobramycin and dibekacin in the guinea pig. A functional and morphological cochlear and vestibular study. Acta Otolaryngol Suppl 390 (1982) 1-30
2. 2+ channels. Br J Pharmacol 126 (1999) 1462-1470
3. Battaglia A., Bodmer D., Brors D., Pak K., Frangos J.A., and Ryan A.F. Involvement of ras activation in toxic hair cell damage of the mammalian cochlea. Neuroscience 122 (2003) 1025-1035
4. Cassidy R.A., Burleson D.G., Delgado A.V., Kohler D.J., Salin M.L., and Pruitt Jr. B.A. Effects of heme proteins on nitric oxide levels and cell viability in isolated PMNs: a mechanism of toxicity. J Leukoc Biol 67 (2000) 357-368
5. Fausti S.A., Rappaport B.Z., Schechter M.A., Frey R.H., Ward T.T., and Brummette R.E. Detection of aminoglycoside ototoxicity by high-frequency auditory evaluation: selected case studies. Am J Otolaryngol 5 (1984) 177-182
6. Fetoni A.R., Sergi B., Ferraresi A., Paludetti G., and Troiani D. Alpha-tocopherol protective effects on gentamicin ototoxicity: an experimental study. Int J Audiol 43 (2004) 166-171
7. Forge A., and Richardson G. Freeze-fracture analysis of apical membranes in cochlear cultures: differences between basal and apical-coil outer hair cells and effects of neomycin. J Neurocytol 22 (1993) 854-867
8. Forge A., and Schacht J. Aminoglycoside antibiotics. Audiol Neurootol 5 (2000) 3-22
9. Frenz D.A., Yoo H., and Liu W. Basilar papilla explants: a model to study hair cell regeneration-repair and protection. Acta Otolaryngol 118 (1998) 651-659
10. Garetz S.L., Altschuler R.A., and Schacht J. Attenuation of gentamicin ototoxicity by glutathione in the guinea pig in vivo. Hear Res 77 (1994) 81-87
11. Hashino E., and Shero M. Endocytosis of aminoglycoside antibiotics in sensory hair cells. Brain Res 704 (1995) 135-140
12. Hashino E., Tin Han E.K., and Salvi R.J. Base-to-apex gradient of cell proliferation in the chick cochlea following kanamycin-induced hair cell loss. Hear Res 88 (1995) 156-168
13. He D.Z., Jia S., and Dallos P. Mechanoelectrical transduction of adult outer hair cells studied in a gerbil hemicochlea. Nature 429 (2004) 766-770
14. Heinrich U.R., Helling K., Sifferath M., Brieger J., Li H., Schmidtmann I., and Mann W.J. Gentamicin increases nitric oxide production and induces hearing loss in guinea pigs. Laryngoscope 118 (2008) 1438-1442
15. Henley C.M., and Rybak L.P. Ototoxicity in developing mammals. Brain Res Brain Res Rev 20 (1995) 68-90
16. Hiel H., Erre J.P., Aurousseau C., Bouali R., Dulon D., and Aran J.M. Gentamicin uptake by cochlear hair cells precedes hearing impairment during chronic treatment. Audiology 32 (1993) 78-87
17. Hinojosa R., Nelson E.G., Lerner S.A., Redleaf M.I., and Schramm D.R. Aminoglycoside ototoxicity: a human temporal bone study. Laryngoscope 111 (2001) 1797-1805
18. Hirose K., Hockenbery D.M., and Rubel E.W. Reactive oxygen species in chick hair cells after gentamicin exposure in vitro. Hear Res 104 (1997) 1-14
19. Hoffman D., Jones-King K.L., Whitworth C., and Rybak L. Potentiation of ototoxicity by glutathione depletion. Ann Otol Rhinol Laryngol 97 (1988) 36-41
20. Kawamoto K., Sha S.H., Minoda R., Izumikawa M., Kuriyama H., Schacht J., and Raphael Y. Antioxidant gene therapy can protect hearing and hair cells from ototoxicity. Mol Ther 9 (2004) 173-181
21. Kros C.J., Rüsch A., and Richardson G.P. Mechano-electrical transducer currents in hair cells of the cultured neonatal mouse cochlea. Proc Biol Sci 249 (1992) 185-193
22. Kuppusamy P., Chzhan M., Vij K., Shteynbuk M., Lefer D.J., Giannella E., and Zweier J.L. Three-dimensional spectral-spatial EPR imaging of free radicals in the heart: a technique for imaging tissue metabolism and oxygenation. Proc Natl Acad Sci U S A 91 (1994) 3388-3392
23. Kushnareva Y., Murphy A.N., and Andreyev A. Complex I-mediated reactive oxygen species generation: modulation by cytochrome c and NAD(P)+ oxidation-reduction state. Biochem J 368 (2002) 545-553
24. Lautermann J., McLaren J., and Schacht J. Glutathione protection against gentamicin ototoxicity depends on nutritional status. Hear Res 86 (1995) 15-24
25. Lee R.L., Westendorf J., and Gold M.R. Differential role of reactive oxygen species in the activation of mitogen-activated protein kinases and Akt by key receptors on B-lymphocytes: CD40, the B cell antigen receptor, and CXCR4. J Cell Commun Signal 1 (2007) 33-43
26. Lenoir M., Marot M., and Uziel A. Comparative ototoxicity of four aminoglycosidic antibiotics during the critical period of cochlear development in the rat. A functional and structural study. Acta Otolaryngol Suppl 405 (1983) 1-16
27. Marcotti W., van Netten S.M., and Kros C.J. The aminoglycoside antibiotic dihydrostreptomycin rapidly enters mouse outer hair cells through the mechano-electrical transducer channels. J Physiol 567 (2005) 505-521
28. McFadden S.L., Ding D., Savemini D., and Salvi R.J. M40403 a superoxide dismutase mimetics protects cochlear hair cells from gentamicin, but not cisplatin toxicity. Toxicol Appl Pharmacol 186 (2003) 46-54
29. Natal C., Modol T., Osés-Prieto J.A., López-Moratalla N., Iraburu M.J., and López-Zabalza M.J. Specific protein nitration in nitric oxide-induced apoptosis of human monocytes. Apoptosis 13 (2008) 1356-1367
30. Patuzzi R.B., and Bull C.L. Electrical responses from the chicken basilar papilla. Hear Res 53 (1991) 57-77
31. Pierson M.G., and Gray B.H. Superoxide dismutase activity in the cochlea. Hear Res 6 (1982) 141-151
32. Pierson M.G., and Møller A.R. Prophylaxis of kanamycin-induced ototoxicity by a radioprotectant. Hear Res 4 (1981) 79-87
33. Priuska E.M., Clark K., Pecoraro V., and Schacht J. NMR spectra of iron-gentamicin complexes and the implications for aminoglycoside toxicity. Inorg Chim Acta 273 (1998) 85-91
34. Priuska E.M., and Schacht J. Formation of free radicals by gentamicin and iron and evidence for an iron/gentamicin complex. Biochem Pharmacol 50 (1995) 1749-1752
35. Ren J.G., Xia H.L., Just T., and Dai Y.R. Hydroxyl radical-induced apoptosis in human tumor cells is associated with telomere shortening but not telomerase inhibition and caspase activation. FEBS Lett 488 (2001) 123-132
36. Richardson G.P., and Russell I.J. Cochlear cultures as a model system for studying aminoglycoside induced ototoxicity. Hear Res 53 (1991) 293-311
37. Santos N.A., Bezerra C.S., Martins N.M., Curti C., Bianchi M.L., and Santos A.C. Hydroxyl radical scavenger ameliorates cisplatin-induced nephrotoxicity by preventing oxidative stress, redox state unbalance, impairment of energetic metabolism and apoptosis in rat kidney mitochondria. Cancer Chemother Pharmacol 61 (2008) 145-155
38. Setsukinai K.I., Urano Y., Kakinuma K., Majima H.J., and Nagano T. Development of novel fluorescence probes that can reliably detect reactive oxygen species and distinguish specific species. J Biol Chem 278 (2003) 3170-3175
39. Sha S.H., and Schacht J. Stimulation of free radical formation by aminoglycoside antibiotics. Hear Res 128 (1999) 112-118
40. Sha S.H., Taylor R., Forge A., and Schacht J. Differential vulnerability of basal and apical hair cells is based on intrinsic susceptibility to free radicals. Hear Res 155 (2001) 1-8
41. Sobkowicz H.M., Loftus J.M., and Slapnick S.M. Tissue culture of the organ of Corti. Acta Otolaryngol Suppl 502 (1993) 3-36
42. Sumitomo K., Shishido N., Aizawa H., Hasebe N., Kikuchi K., and Nakamura M. Effects of MCI-186 upon neutrophil-derived active oxygens. Redox Rep 12 (2007) 189-194
43. Tanaka K., and Smith C.A. Structure of the chicken's inner ear: SEM and TEM study. Am J Anat 153 (1978) 251-271
44. Taylor E.L., Li J.T., Tupper J.C., Rossi A.G., Winn R.K., and Harlan J.M. GEA 3162, a peroxynitrite donor, induces Bcl-2-sensitive, p53-independent apoptosis in murine bone marrow cells. Biochem Pharmacol 74 (2007) 1039-1049
45. Theopold H.M. Comparative surface studies of ototoxic effects of various aminoglycoside antibiotics on the organ of Corti in the guinea pig. A scanning electron microscopic study. Acta Otolaryngol 84 (1977) 57-64
46. Ton C., and Parng C. The use of zebrafish for assessing ototoxic and otoprotective agents. Hear Res 208 (2005) 79-88
47. Tran Ba Huy T.P., Bernard P., and Schacht J. Kinetics of gentamicin uptake and release in the rat. J Clin Invest 77 (1986) 1492-1500
48. Usami S., Hjelle O.P., and Ottersen O.P. Differential cellular distribution of glutathione, an endogenous antioxidant, in the guinea pig inner ear. Brain Res 743 (1996) 337-340
49. Van de Water T., and Ruben R.J. Growth of the inner ear in organ culture. Ann Otol Rhinol Laryngol 83 (1974) 1-16
50. Warner D.S., Sheng H., and Batinić-Haberle I. Oxidants, antioxidants and the ischemic brain. J Exp Biol 207 (2004) 3221-3231
51. Watanabe K., and Yagi T. Expression of myeloperoxidase in the inner ear of cisplatin-treated guinea pigs. Anticancer Drugs 11 (2000) 727-730
52. Wiseman H., and Halliwell B. Damage to DNA by reactive oxygen and nitrogen species role in inflammatory disease and progression to cancer. Biochem J 313 (1996) 17-29
53. Yasui H., and Sakurai H. Chemiluminescent detection and imaging of reactive oxygen species in live mouse skin exposed to UVA. Biochem Biophys Res Commun 269 (2000) 131-136