Keratin 8 and 18 loss in epithelial cancer cells increases collective cell migration and cisplatin sensitivity through claudin1 up-regulation

Journal of Biological Chemistry

Volumn 288, Issue 16, 2013, Pages 11555-11571

  Fortier, Anne Marie ^a   Asselin, Eric ^a   Cadrin, Monique ^a  

^a UNIVERSITÉ DU QUÉBEC À TROIS RIVIÈRES   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER CELLS; CIS-PLATIN; COLLECTIVE CELL MIGRATIONS; EPITHELIAL CANCER CELLS; EPITHELIAL-MESENCHYMAL TRANSITION; KERATIN 8; TUMOR PROGRESSIONS; UP-REGULATION;

CELLS; PLATINUM COMPOUNDS;

KERATIN;

CISPLATIN; CLAUDIN 1; CYTOKERATIN 18; CYTOKERATIN 8; GELATINASE A; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SHORT HAIRPIN RNA;

ARTICLE; CANCER CELL; CANCER GROWTH; CELL INVASION; CELL MIGRATION; CHEMOSENSITIVITY; CONTROLLED STUDY; DRUG CYTOTOXICITY; EPITHELIAL MESENCHYMAL TRANSITION; GENE SILENCING; HUMAN; HUMAN CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; UPREGULATION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL MOVEMENT; CISPLATIN; CLAUDIN-1; ENZYME ACTIVATION; EPITHELIAL-MESENCHYMAL TRANSITION; FAS LIGAND PROTEIN; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; HELA CELLS; HEP G2 CELLS; HUMANS; KERATIN-18; KERATIN-8; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; NEOPLASMS, GLANDULAR AND EPITHELIAL; NF-KAPPA B; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; UP-REGULATION;

EID: 84876535165     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.428920     Document Type: Article

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