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Volumn 174, Issue 1, 2006, Pages 115-125

A disease- and phosphorylation-related nonmechanical function for keratin 8

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; CYSTINE; FAS ANTIBODY; GLYCINE; KERATIN; MUTANT PROTEIN; PROTEIN KERATIN 18; PROTEIN KERATIN 8; SERINE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

EID: 33745628320     PISSN: 00219525     EISSN: 00219525     Source Type: Journal    
DOI: 10.1083/jcb.200602146     Document Type: Article
Times cited : (146)

References (58)
  • 1
    • 11144307292 scopus 로고    scopus 로고
    • STRESS signaling pathways that modulate cardiac myocyte apoptosis
    • Baines, C.P., and J.D. Molkentin. 2005. STRESS signaling pathways that modulate cardiac myocyte apoptosis. J. Mol. Cell. Cardiol. 38:47-62.
    • (2005) J. Mol. Cell. Cardiol. , vol.38 , pp. 47-62
    • Baines, C.P.1    Molkentin, J.D.2
  • 2
    • 0028607055 scopus 로고
    • Colorectal hyperplasia and inflammation in keratin 8-deficient FVB/N mice
    • Baribault, H., J. Penner, R.V. Iozzo, and M. Wilson-Heiner. 1994. Colorectal hyperplasia and inflammation in keratin 8-deficient FVB/N mice. Genes Dev. 8:2964-2973.
    • (1994) Genes Dev. , vol.8 , pp. 2964-2973
    • Baribault, H.1    Penner, J.2    Iozzo, R.V.3    Wilson-Heiner, M.4
  • 3
    • 0032979438 scopus 로고    scopus 로고
    • Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation
    • Behrens, A., M. Sibilia, and E.F. Wagner. 1999. Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation. Nat. Genet. 21:326-329.
    • (1999) Nat. Genet. , vol.21 , pp. 326-329
    • Behrens, A.1    Sibilia, M.2    Wagner, E.F.3
  • 5
    • 0034599872 scopus 로고    scopus 로고
    • Keratin-dependent, epithelial resistance to tumor necrosis factor-induced apoptosis
    • Caulin, C., C.F. Ware, T.M. Magin, and R.G. Oshima. 2000. Keratin-dependent, epithelial resistance to tumor necrosis factor-induced apoptosis. J. Cell Biol. 149:17-22.
    • (2000) J. Cell Biol. , vol.149 , pp. 17-22
    • Caulin, C.1    Ware, C.F.2    Magin, T.M.3    Oshima, R.G.4
  • 6
    • 0036468732 scopus 로고    scopus 로고
    • "Hard" and "soft" principles defining the structure, function and regulation of keratin intermediate filaments
    • Coulombe, P.A., and M.B. Omary. 2002. "Hard" and "soft" principles defining the structure, function and regulation of keratin intermediate filaments. Curr. Opin. Cell Biol. 14:110-122.
    • (2002) Curr. Opin. Cell Biol. , vol.14 , pp. 110-122
    • Coulombe, P.A.1    Omary, M.B.2
  • 7
    • 0032479983 scopus 로고    scopus 로고
    • Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB
    • Deak, M., A.D. Clifton, L.M. Lucocq, and D.R. Alessi. 1998. Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB. EMBO J. 17:4426-4441.
    • (1998) EMBO J. , vol.17 , pp. 4426-4441
    • Deak, M.1    Clifton, A.D.2    Lucocq, L.M.3    Alessi, D.R.4
  • 8
    • 0028283501 scopus 로고
    • Intermediate filaments: Structure, dynamics, function, and disease
    • Fuchs, E., and K. Weber. 1994. Intermediate filaments: structure, dynamics, function, and disease. Annu. Rev. Biochem. 63:345-382.
    • (1994) Annu. Rev. Biochem. , vol.63 , pp. 345-382
    • Fuchs, E.1    Weber, K.2
  • 9
    • 0032559341 scopus 로고    scopus 로고
    • A structural scaffolding of intermediate filaments in health and disease
    • Fuchs, E., and D.W. Cleveland. 1998. A structural scaffolding of intermediate filaments in health and disease. Science. 279:514-519.
    • (1998) Science , vol.279 , pp. 514-519
    • Fuchs, E.1    Cleveland, D.W.2
  • 10
    • 0036731701 scopus 로고    scopus 로고
    • Mixed-lineage kinase control of JNK and p38 MAPK pathways
    • Gallo, K.A., and G.L. Johnson. 2002. Mixed-lineage kinase control of JNK and p38 MAPK pathways. Nat. Rev. Mol. Cell Biol. 3:663-672.
    • (2002) Nat. Rev. Mol. Cell Biol. , vol.3 , pp. 663-672
    • Gallo, K.A.1    Johnson, G.L.2
  • 11
    • 0035921430 scopus 로고    scopus 로고
    • Simple epithelium keratins 8 and 18 provide resistance to Fas-mediated apoptosis. The protection occurs through a receptor-targeting modulation
    • Gilbert, S., A. Loranger, N. Daigle, and N. Marceau. 2001. Simple epithelium keratins 8 and 18 provide resistance to Fas-mediated apoptosis. The protection occurs through a receptor-targeting modulation. J. Cell Biol. 154:763-773.
    • (2001) J. Cell Biol. , vol.154 , pp. 763-773
    • Gilbert, S.1    Loranger, A.2    Daigle, N.3    Marceau, N.4
  • 12
    • 3543009577 scopus 로고    scopus 로고
    • Keratins modulate c-Flip/extracellular signal-regulated kinase 1 and 2 antiapoptotic signaling in simple epithelial cells
    • Gilbert, S., A. Loranger, and N. Marceau. 2004. Keratins modulate c-Flip/extracellular signal-regulated kinase 1 and 2 antiapoptotic signaling in simple epithelial cells. Mol. Cell. Biol. 24:7072-7081.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 7072-7081
    • Gilbert, S.1    Loranger, A.2    Marceau, N.3
  • 13
    • 0037192809 scopus 로고    scopus 로고
    • The intermediate filament protein keratin 8 is a novel cytoplasmic substrate for c-Jun N-terminal kinase
    • He, T., A. Stepulak, T.H. Holmstrom, M.B. Omary, and J.E. Eriksson. 2002. The intermediate filament protein keratin 8 is a novel cytoplasmic substrate for c-Jun N-terminal kinase. J. Biol. Chem. 277:10767-10774.
    • (2002) J. Biol. Chem. , vol.277 , pp. 10767-10774
    • He, T.1    Stepulak, A.2    Holmstrom, T.H.3    Omary, M.B.4    Eriksson, J.E.5
  • 14
    • 3943078618 scopus 로고    scopus 로고
    • Intermediate filaments: Molecular structure, assembly mechanism, and integration into functionally distinct intracellular scaffolds
    • Herrmann, H., and U. Aebi. 2004. Intermediate filaments: molecular structure, assembly mechanism, and integration into functionally distinct intracellular scaffolds. Annu. Rev. Biochem. 73:749-789.
    • (2004) Annu. Rev. Biochem. , vol.73 , pp. 749-789
    • Herrmann, H.1    Aebi, U.2
  • 15
    • 12344252237 scopus 로고    scopus 로고
    • AP-1 subunits: Quarrel and harmony among siblings
    • Hess, J., P. Angel, and M. Schorpp-Kistner. 2004. AP-1 subunits: quarrel and harmony among siblings. J. Cell Sci. 117:5965-5973.
    • (2004) J. Cell Sci. , vol.117 , pp. 5965-5973
    • Hess, J.1    Angel, P.2    Schorpp-Kistner, M.3
  • 18
    • 0036257307 scopus 로고    scopus 로고
    • Biochemical and cellular mechanisms of toxic liver injury
    • Kaplowitz, N. 2002. Biochemical and cellular mechanisms of toxic liver injury. Semin. Liver Dis. 22:137-144.
    • (2002) Semin. Liver Dis. , vol.22 , pp. 137-144
    • Kaplowitz, N.1
  • 19
    • 0025361520 scopus 로고
    • Organization and sequence of the human gene encoding cytokeratin 8
    • Krauss, S., and W.W. Franke. 1990. Organization and sequence of the human gene encoding cytokeratin 8. Gene. 86:241-249.
    • (1990) Gene , vol.86 , pp. 241-249
    • Krauss, S.1    Franke, W.W.2
  • 20
    • 0028865145 scopus 로고
    • Chronic hepatitis, hepatocyte fragility, and increased soluble phosphoglycokeratins in transgenic mice expressing a keratin 18 conserved arginine mutant
    • Ku, N.O., S. Michie, R.G. Oshima, and M.B. Omary. 1995. Chronic hepatitis, hepatocyte fragility, and increased soluble phosphoglycokeratins in transgenic mice expressing a keratin 18 conserved arginine mutant. J. Cell Biol. 131:1303-1314.
    • (1995) J. Cell Biol. , vol.131 , pp. 1303-1314
    • Ku, N.O.1    Michie, S.2    Oshima, R.G.3    Omary, M.B.4
  • 22
    • 0031029525 scopus 로고    scopus 로고
    • Mutation of human keratin 18 in association with cryptogenic cirrhosis
    • Ku, N.O., T.L. Wright, N.A. Terrault, R. Gish, and M.B. Omary. 1997. Mutation of human keratin 18 in association with cryptogenic cirrhosis. J. Clin. Invest. 99:19-23.
    • (1997) J. Clin. Invest. , vol.99 , pp. 19-23
    • Ku, N.O.1    Wright, T.L.2    Terrault, N.A.3    Gish, R.4    Omary, M.B.5
  • 23
    • 0032576580 scopus 로고    scopus 로고
    • Mutation of a major keratin phosphorylation site predisposes to hepatotoxic injury in transgenic mice
    • Ku, N.O., S.A. Michie, R.M. Soetikno, E.Z. Resurreccion, R.L. Broome, and M.B. Omary. 1998. Mutation of a major keratin phosphorylation site predisposes to hepatotoxic injury in transgenic mice. J. Cell Biol. 143:2023-2032.
    • (1998) J. Cell Biol. , vol.143 , pp. 2023-2032
    • Ku, N.O.1    Michie, S.A.2    Soetikno, R.M.3    Resurreccion, E.Z.4    Broome, R.L.5    Omary, M.B.6
  • 24
    • 0033401358 scopus 로고    scopus 로고
    • The cytoskeleton of digestive epithelia in health and disease
    • Ku, N.O., X. Zhou, D.M. Toivola, and M.B. Omary. 1999. The cytoskeleton of digestive epithelia in health and disease. Am. J. Physiol. 277:G1108-G1137.
    • (1999) Am. J. Physiol. , vol.277
    • Ku, N.O.1    Zhou, X.2    Toivola, D.M.3    Omary, M.B.4
  • 25
    • 0035942786 scopus 로고    scopus 로고
    • Keratin 8 mutations in patients with cryptogenic liver disease
    • Ku, N.O., R. Gish, T.L. Wright, and M.B. Omary. 2001. Keratin 8 mutations in patients with cryptogenic liver disease. N. Engl. J. Med. 344:1580-1587.
    • (2001) N. Engl. J. Med. , vol.344 , pp. 1580-1587
    • Ku, N.O.1    Gish, R.2    Wright, T.L.3    Omary, M.B.4
  • 26
    • 0037192772 scopus 로고    scopus 로고
    • Keratin 8 phosphorylation by p38 kinase regulates cellular keratin filament reorganization: Modulation by a keratin 1-like disease causing mutation
    • Ku, N.O., S. Azhar, and M.B. Omary. 2002. Keratin 8 phosphorylation by p38 kinase regulates cellular keratin filament reorganization: modulation by a keratin 1-like disease causing mutation. J. Biol. Chem. 277:10775-10782.
    • (2002) J. Biol. Chem. , vol.277 , pp. 10775-10782
    • Ku, N.O.1    Azhar, S.2    Omary, M.B.3
  • 27
    • 0037847551 scopus 로고    scopus 로고
    • Keratin mutation in transgenic mice predisposes to Fas but not TNF-induced apoptosis and massive liver injury
    • Ku, N.O., R.M. Soetikno, and M.B. Omary. 2003. Keratin mutation in transgenic mice predisposes to Fas but not TNF-induced apoptosis and massive liver injury. Hepatology. 37:1006-1014.
    • (2003) Hepatology , vol.37 , pp. 1006-1014
    • Ku, N.O.1    Soetikno, R.M.2    Omary, M.B.3
  • 30
    • 0027435152 scopus 로고
    • Vimentin serves as a phosphate sink during the apparent activation of protein kinases by okadaic acid in mammalian cells
    • Lai, Y.K., W.C. Lee, and K.D. Chen. 1993. Vimentin serves as a phosphate sink during the apparent activation of protein kinases by okadaic acid in mammalian cells. J. Cell. Biochem. 53:161-168.
    • (1993) J. Cell. Biochem. , vol.53 , pp. 161-168
    • Lai, Y.K.1    Lee, W.C.2    Chen, K.D.3
  • 31
    • 0030857803 scopus 로고    scopus 로고
    • Stress, apoptosis, and mitosis induce phosphorylation of human keratin 8 at Ser-73 in tissues and cultured cells
    • Liao, J., N.O. Ku, and M.B. Omary. 1997. Stress, apoptosis, and mitosis induce phosphorylation of human keratin 8 at Ser-73 in tissues and cultured cells. J. Biol. Chem. 272:17565-17573.
    • (1997) J. Biol. Chem. , vol.272 , pp. 17565-17573
    • Liao, J.1    Ku, N.O.2    Omary, M.B.3
  • 32
    • 16844387124 scopus 로고    scopus 로고
    • Role of JNK activation in apoptosis: A double-edged sword
    • Liu, J., and A. Lin. 2005. Role of JNK activation in apoptosis: a double-edged sword. Cell Res. 15:36-42.
    • (2005) Cell Res. , vol.15 , pp. 36-42
    • Liu, J.1    Lin, A.2
  • 33
    • 22544450456 scopus 로고    scopus 로고
    • Altered axonal architecture by removal of the heavily phosphorylated neurofilament tail domains strongly slows superoxide dismutase 1 mutant-mediated ALS
    • Lobsiger, C.S., M.L. Garcia, C.M. Ward, and D.W. Cleveland. 2005. Altered axonal architecture by removal of the heavily phosphorylated neurofilament tail domains strongly slows superoxide dismutase 1 mutant-mediated ALS. Proc. Natl. Acad. Sci. USA. 102:10351-10356.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 10351-10356
    • Lobsiger, C.S.1    Garcia, M.L.2    Ward, C.M.3    Cleveland, D.W.4
  • 35
    • 2642684550 scopus 로고    scopus 로고
    • Lessons from keratin 18 knockout mice: Formation of novel keratin filaments, secondary loss of keratin 7 and accumulation of liver-specific keratin 8-positive aggregates
    • Magin, T.M., R. Schroder, S. Leitgeb, F. Wanninger, K. Zatloukal, C. Grund, and D.W. Melton. 1998. Lessons from keratin 18 knockout mice: formation of novel keratin filaments, secondary loss of keratin 7 and accumulation of liver-specific keratin 8-positive aggregates. J. Cell Biol. 140:1441-1451.
    • (1998) J. Cell Biol. , vol.140 , pp. 1441-1451
    • Magin, T.M.1    Schroder, R.2    Leitgeb, S.3    Wanninger, F.4    Zatloukal, K.5    Grund, C.6    Melton, D.W.7
  • 36
    • 6344280832 scopus 로고    scopus 로고
    • Emerging functions: Diseases and animal models reshape our view of the cytoskeleton
    • Magin, T.M., J. Reichelt, and M. Hatzfeld. 2004. Emerging functions: diseases and animal models reshape our view of the cytoskeleton. Exp. Cell Res. 301:91-102.
    • (2004) Exp. Cell Res. , vol.301 , pp. 91-102
    • Magin, T.M.1    Reichelt, J.2    Hatzfeld, M.3
  • 37
    • 85047681520 scopus 로고    scopus 로고
    • Keratin-mediated resistance to stress and apoptosis in simple epithelial cells in relation to health and disease
    • Marceau, N., A. Loranger, S. Gilbert, N. Daigle, and S. Champetier. 2001. Keratin-mediated resistance to stress and apoptosis in simple epithelial cells in relation to health and disease. Biochem. Cell Biol. 79:543-555.
    • (2001) Biochem. Cell Biol. , vol.79 , pp. 543-555
    • Marceau, N.1    Loranger, A.2    Gilbert, S.3    Daigle, N.4    Champetier, S.5
  • 38
    • 0020467073 scopus 로고
    • The catalog of human cytokeratins: Patterns of expression in normal epithelia, tumors and cultured cells
    • Moll, R., W.W. Franke, D.L. Schiller, B. Geiger, and R. Krepler. 1982. The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells. Cell. 31:11-24.
    • (1982) Cell , vol.31 , pp. 11-24
    • Moll, R.1    Franke, W.W.2    Schiller, D.L.3    Geiger, B.4    Krepler, R.5
  • 39
    • 17744368458 scopus 로고    scopus 로고
    • Deregulation of Cdk5 in a mouse model of ALS: Toxicity alleviated by perikaryal neurofilament inclusions
    • Nguyen, M.D., R.C. Lariviere, and J.P. Julien. 2001. Deregulation of Cdk5 in a mouse model of ALS: toxicity alleviated by perikaryal neurofilament inclusions. Neuron. 30:135-147.
    • (2001) Neuron , vol.30 , pp. 135-147
    • Nguyen, M.D.1    Lariviere, R.C.2    Julien, J.P.3
  • 40
    • 0032233993 scopus 로고    scopus 로고
    • Keratin modifications and solubility properties in epithelial cells and in vitro
    • Omary, M.B., N.O. Ku, J. Liao, and D. Price. 1998. Keratin modifications and solubility properties in epithelial cells and in vitro. Subcell. Biochem. 31:105-140.
    • (1998) Subcell. Biochem. , vol.31 , pp. 105-140
    • Omary, M.B.1    Ku, N.O.2    Liao, J.3    Price, D.4
  • 41
    • 0036151839 scopus 로고    scopus 로고
    • Keratins: Guardians of the liver
    • Omary, M.B., N.O. Ku, and D.M. Toivola. 2002. Keratins: guardians of the liver. Hepatology. 35:251-257.
    • (2002) Hepatology , vol.35 , pp. 251-257
    • Omary, M.B.1    Ku, N.O.2    Toivola, D.M.3
  • 42
    • 6344273968 scopus 로고    scopus 로고
    • Intermediate filament proteins and their associated diseases
    • Omary, M.B., P.A. Coulombe, and W.H. McLean. 2004. Intermediate filament proteins and their associated diseases. N. Engl. J. Med. 351:2087-2100.
    • (2004) N. Engl. J. Med. , vol.351 , pp. 2087-2100
    • Omary, M.B.1    Coulombe, P.A.2    McLean, W.H.3
  • 44
    • 0041965745 scopus 로고    scopus 로고
    • TNF-alpha-induced cell death in ethanol-exposed cells depends on p38 MAPK signaling but is independent of Bid and caspase-8
    • Pastorino, J.G., N. Shulga, and J.B. Hoek. 2003. TNF-alpha-induced cell death in ethanol-exposed cells depends on p38 MAPK signaling but is independent of Bid and caspase-8. Am. J. Physiol. Gastrointest. Liver Physiol. 285:G503-G516.
    • (2003) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.285
    • Pastorino, J.G.1    Shulga, N.2    Hoek, J.B.3
  • 45
    • 0037407006 scopus 로고    scopus 로고
    • Phenotypes, genotypes and their contribution to understanding keratin function
    • Porter, R.M., and E.B. Lane. 2003. Phenotypes, genotypes and their contribution to understanding keratin function. Trends Genet. 19:278-285.
    • (2003) Trends Genet. , vol.19 , pp. 278-285
    • Porter, R.M.1    Lane, E.B.2
  • 46
    • 22844440003 scopus 로고    scopus 로고
    • Involvement of NADPH oxidase isoforms and Src family kinases in CD95-dependent hepatocyte apoptosis
    • Reinehr, R., S. Becker, A. Eberle, S. Grether-Beck, and D. Haussinger. 2005. Involvement of NADPH oxidase isoforms and Src family kinases in CD95-dependent hepatocyte apoptosis. J. Biol. Chem. 280:27179-27194.
    • (2005) J. Biol. Chem. , vol.280 , pp. 27179-27194
    • Reinehr, R.1    Becker, S.2    Eberle, A.3    Grether-Beck, S.4    Haussinger, D.5
  • 47
    • 2942530310 scopus 로고    scopus 로고
    • ERK and p38 MAPK-activated protein kinases: A family of protein kinases with diverse biological functions
    • Roux, P.P., and J. Blenis. 2004. ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions. Microbiol. Mol. Biol. Rev. 68:320-344.
    • (2004) Microbiol. Mol. Biol. Rev. , vol.68 , pp. 320-344
    • Roux, P.P.1    Blenis, J.2
  • 48
    • 2942744672 scopus 로고    scopus 로고
    • Fas-mediated apoptosome formation is dependent on reactive oxygen species derived from mitochondrial permeability transition in Jurkat cells
    • Sato, T., T. Machida, S. Takahashi, S. Iyama, Y. Sato, K. Kuribayashi, K. Takada, T. Oku, Y. Kawano, T. Okamoto, et al. 2004. Fas-mediated apoptosome formation is dependent on reactive oxygen species derived from mitochondrial permeability transition in Jurkat cells. J. Immunol. 173:285-296.
    • (2004) J. Immunol. , vol.173 , pp. 285-296
    • Sato, T.1    Machida, T.2    Takahashi, S.3    Iyama, S.4    Sato, Y.5    Kuribayashi, K.6    Takada, K.7    Oku, T.8    Kawano, Y.9    Okamoto, T.10
  • 49
    • 33745532017 scopus 로고    scopus 로고
    • Keratin variants associate with progression of fibrosis during chronic hepatitis C infection
    • Strnad, P., T.C. Lienau, G.Z. Tao, L.C. Lazzeroni, F. Stickel, D. Schuppan, and M.B. Omary. 2006a. Keratin variants associate with progression of fibrosis during chronic hepatitis C infection. Hepatology. 43:1354-1363.
    • (2006) Hepatology , vol.43 , pp. 1354-1363
    • Strnad, P.1    Lienau, T.C.2    Tao, G.Z.3    Lazzeroni, L.C.4    Stickel, F.5    Schuppan, D.6    Omary, M.B.7
  • 50
    • 33646337924 scopus 로고    scopus 로고
    • Denaturing temperature selection may underestimate keratin mutation detection by DHPLC
    • Strnad, P., T.C. Lienau, G.Z. Tao, N.O. Ku, T.M. Magin, and M.B. Omary. 2006b. Denaturing temperature selection may underestimate keratin mutation detection by DHPLC. Hum. Mutat. 27:444-452.
    • (2006) Hum. Mutat. , vol.27 , pp. 444-452
    • Strnad, P.1    Lienau, T.C.2    Tao, G.Z.3    Ku, N.O.4    Magin, T.M.5    Omary, M.B.6
  • 52
    • 0035985154 scopus 로고    scopus 로고
    • Type II keratins are phosphorylated on a unique motif during stress and mitosis in tissues and cultured cells
    • Toivola, D.M., Q. Zhou, L.S. English, and M.B. Omary. 2002. Type II keratins are phosphorylated on a unique motif during stress and mitosis in tissues and cultured cells. Mol. Biol. Cell. 13:1857-1870.
    • (2002) Mol. Biol. Cell , vol.13 , pp. 1857-1870
    • Toivola, D.M.1    Zhou, Q.2    English, L.S.3    Omary, M.B.4
  • 53
    • 4043154985 scopus 로고    scopus 로고
    • Keratin 8 and 18 hyperphosphorylation is a marker of progression of human liver disease
    • Toivola, D.M., N.O. Ku, E.Z. Resurreccion, D.R. Nelson, T.L. Wright, and M.B. Omary. 2004. Keratin 8 and 18 hyperphosphorylation is a marker of progression of human liver disease. Hepatology. 40:459-466.
    • (2004) Hepatology , vol.40 , pp. 459-466
    • Toivola, D.M.1    Ku, N.O.2    Resurreccion, E.Z.3    Nelson, D.R.4    Wright, T.L.5    Omary, M.B.6
  • 54
    • 27744556965 scopus 로고    scopus 로고
    • Beyond cellular integrity: Organelle-related and protein-targeting functions of intermediate filaments
    • Toivola, D.M., G.Z. Tao, A. Habtezion, J. Liao, and M.B. Omary. 2005. Beyond cellular integrity: organelle-related and protein-targeting functions of intermediate filaments. Trends Cell Biol. 15:608-617.
    • (2005) Trends Cell Biol. , vol.15 , pp. 608-617
    • Toivola, D.M.1    Tao, G.Z.2    Habtezion, A.3    Liao, J.4    Omary, M.B.5
  • 57
    • 2342434472 scopus 로고    scopus 로고
    • Organ-specific stress induces mouse pancreatic keratin overexpression in association with NF-κB activation
    • Zhong, B., Q. Zhou, D.M. Toivola, G.Z. Tao, E.Z. Resurreccion, and M.B. Omary. 2004. Organ-specific stress induces mouse pancreatic keratin overexpression in association with NF-κB activation. J. Cell Sci. 117:1709-1719.
    • (2004) J. Cell Sci. , vol.117 , pp. 1709-1719
    • Zhong, B.1    Zhou, Q.2    Toivola, D.M.3    Tao, G.Z.4    Resurreccion, E.Z.5    Omary, M.B.6


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