Critical solvent properties affecting the particle formation process and characteristics of celecoxib-loaded PLGA microparticles via spray-drying

Pharmaceutical Research

Volumn 30, Issue 4, 2013, Pages 1065-1076

  Wan, Feng ^a   Bohr, Adam ^a,b   Maltesen, Morten Jonas ^c   Bjerregaard, Simon ^d   Foged, Camilla ^a   Rantanen, Jukka ^a   Yang, Mingshi ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c NOVOZYMES A S   (Denmark)

^d NOVO NORDISK A S   (Denmark)

Author keywords

celecoxib; microparticles; particle formation; poly (lactic co glycolic acid); spray drying

Indexed keywords

ACETONE; CELECOXIB; DRUG CARRIER; METHANOL; POLYGLACTIN; SOLVENT;

ARTICLE; CHEMICAL COMPOSITION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG SOLUBILITY; EVAPORATION; PARTICLE SIZE; PRIORITY JOURNAL; SOLID STATE; SPRAY DRYING; SURFACE PROPERTY; THERMOGRAVIMETRY;

CYCLOOXYGENASE 2 INHIBITORS; DESICCATION; DRUG CARRIERS; LACTIC ACID; PARTICLE SIZE; POLYGLYCOLIC ACID; PYRAZOLES; SOLVENTS; SULFONAMIDES; SURFACE PROPERTIES;

EID: 84876478455     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-012-0943-x     Document Type: Article

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