Particle engineering of materials for oral inhalation by dry powder inhalers. i - Particles of sugar excipients (trehalose and raffinose) for protein delivery

International Journal of Pharmaceutics

Volumn 405, Issue 1-2, 2011, Pages 23-35

  Ógáin, Orla Ní ^a   Li, Jianhe ^a   Tajber, Lidia ^a   Corrigan, Owen I ^a   Healy, Anne Marie ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

Amorphous; Lysozyme; Microparticles; Nanoporous; Proteins; Pulmonary delivery; Raffinose; Spray drying; Stability; Sugars; Trehalose

Indexed keywords

ALCOHOL; LYSOZYME; MICROSPHERE; NANOPARTICLE; NANOPOROUS MICROPARTICLE; RAFFINOSE; TREHALOSE; UNCLASSIFIED DRUG; WATER;

AQUEOUS SOLUTION; ARTICLE; DRUG DELIVERY SYSTEM; DRUG FORMULATION; GLASS TRANSITION TEMPERATURE; IN VITRO STUDY; INHALATION; INHALER; NANOTECHNOLOGY; POWDER INHALER; PRIORITY JOURNAL; PROTEIN STABILITY; PROTEIN TRANSPORT; SPRAY DRYING; X RAY DIFFRACTION;

ADMINISTRATION, INHALATION; DRUG COMPOUNDING; DRUG STABILITY; DRY POWDER INHALERS; EXCIPIENTS; MURAMIDASE; PARTICLE SIZE; PHYSICOCHEMICAL PHENOMENA; POWDERS; RAFFINOSE; TREHALOSE;

EID: 79151477339     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2010.11.039     Document Type: Article

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