A novel interaction between aging and ER overload in a protein conformational dementia

Genetics

Volumn 193, Issue 3, 2013, Pages 865-876

  Schipanski, Angela ^a,d   Lange, Sascha ^a   Segref, Alexandra ^b   Gutschmidt, Aljona ^b   Lomas, David A ^c   Miranda, Elena ^a,c   Schweizer, Michaela ^a   Hoppe, Thorsten ^b   Glatzel, Markus ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b UNIVERSITY OF COLOGNE   (Germany)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d SWISS FEDERAL LABORATORIES FOR MATERIALS SCIENCE AND TECHNOLOGY   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CAENORHABDITIS ELEGANS PROTEIN; FAMILIAL ENCEPHALOPATHY WITH NEUROSERPIN INCLUSION BODY; MEMBRANE PROTEIN; NEUROSERPIN; PROTEIN SRP 2; UNCLASSIFIED DRUG;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; DEMENTIA; DOWN REGULATION; ENDOPLASMIC RETICULUM; GENE OVEREXPRESSION; HEAT SHOCK RESPONSE; HUMAN; IN VIVO STUDY; MOUSE; NONHUMAN; PARKINSONISM; POINT MUTATION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN HOMEOSTASIS; TAUOPATHY; UNFOLDED PROTEIN RESPONSE; WORM;

AGE FACTORS; AMINO ACID SEQUENCE; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; HEAT-SHOCK RESPONSE; HIPPOCAMPUS; HUMANS; INCLUSION BODIES; MICE; MICE, MUTANT STRAINS; MOLECULAR SEQUENCE DATA; NEURONS; NEUROPEPTIDES; POINT MUTATION; POLYMERIZATION; PROTEIN CONFORMATION; PROTEIN FOLDING; SERPINS; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE;

CAENORHABDITIS ELEGANS; MUS;

EID: 84876428891     PISSN: 00166731     EISSN: 19432631     Source Type: Journal    
DOI: 10.1534/genetics.112.149088     Document Type: Article

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