Neuroserpin polymers activate NF-κB by a calcium signaling pathway that is independent of the unfolded protein response

Journal of Biological Chemistry

Volumn 284, Issue 27, 2009, Pages 18202-18209

  Davies, Mark J ^a   Miranda, Elena ^a   Roussel, Benoit D ^a   Kaufman, Randal J ^b   Marciniak, Stefan J ^a   Lomas, David A ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOSOMAL DOMINANTS; CALCIUM SIGNALING; ENDOPLASMIC RETICULUM; FOLDED STRUCTURES; INCLUSION BODIES; INTRACELLULAR CALCIUM; NEUROSERPIN; ORDERED POLYMERS; SERPINS; UNFOLDED PROTEIN RESPONSE;

CALCIUM; CALCIUM ALLOYS;

POLYMERS;

ACTIVATING TRANSCRIPTION FACTOR 6; CALCIUM ION; CELL PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NEUROSERPIN; POLYMER; PROTEIN IRE1; PROTEIN PERK; SERINE PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CELL LINE; CELL STRAIN; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; FIBROBLAST; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN STRUCTURE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; ANTIBODIES; CALCIUM; CALCIUM SIGNALING; CELL LINE, TRANSFORMED; ENDOPLASMIC RETICULUM; EUKARYOTIC INITIATION FACTOR-2; FIBROBLASTS; HUMANS; MICE; MICE, MUTANT STRAINS; MUTAGENESIS; NEUROPEPTIDES; NF-KAPPA B; PC12 CELLS; PHOSPHORYLATION; POLYMERS; PROTEIN FOLDING; RABBITS; RATS; SERPINS; TRANSFECTION;

EID: 67650526104     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.010744     Document Type: Article

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