Loss of phosphoinositide 3-kinase p110g is protective in the acute phase but detrimental in the resolution phase of hapten-induced colitis

Inflammatory Bowel Diseases

Volumn 19, Issue 3, 2013, Pages 489-500

  Prescott, David ^a,b   Atkinson, Bronwyn ^a,b   Döring, Axinia ^a,b   Brown, Shannon ^a,b,c   Petri, Björn ^b   Mckay, Derek M ^a,b   Waterhouse, Christopher C M ^a,b,c  

^a UNIVERSITY OF CALGARY   (Canada)

^b UNIVERSITY OF CALGARY   (Canada)

^c ALBERTA CHILDREN S HOSPITAL RESEARCH INSTITUTE   (Canada)

Author keywords

Crohn's disease; IBD; Neutrophils; TNBS

Indexed keywords

INTERLEUKIN 6; MYELOPEROXIDASE; PHOSPHATIDYLINOSITOL 3 KINASE GAMMA; TRINITROBENZENESULFONIC ACID; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; COLITIS; COLON; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE ACTIVITY; FEMALE; INFLAMMATION; KNOCKOUT GENE; MALE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; WEIGHT REDUCTION; WILD TYPE;

ACUTE DISEASE; ANIMALS; BACTERIAL TRANSLOCATION; BIOLOGICAL MARKERS; CHRONIC DISEASE; CLASS IB PHOSPHATIDYLINOSITOL 3-KINASE; COLITIS; CYTOKINES; FLUORESCENT ANTIBODY TECHNIQUE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEUTROPHIL INFILTRATION; PEROXIDASE; PHAGOCYTOSIS; REAL-TIME POLYMERASE CHAIN REACTION; SEVERITY OF ILLNESS INDEX; TRINITROBENZENESULFONIC ACID; WEIGHT LOSS;

EID: 84876404323     PISSN: 10780998     EISSN: 15364844     Source Type: Journal    
DOI: 10.1097/MIB.0b013e31827feb84     Document Type: Article

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