-
1
-
-
0034865456
-
Rho GTPases and cell migration
-
Ridley A.J. Rho GTPases and cell migration. J. Cell Sci. 114:2001;2713-2722.
-
(2001)
J. Cell Sci.
, vol.114
, pp. 2713-2722
-
-
Ridley, A.J.1
-
3
-
-
0033647242
-
Phosphoinositide 3-kinase: A key biochemical signal for cell migration in response to chemokines
-
Sotsios Y., Ward S.G. Phosphoinositide 3-kinase a key biochemical signal for cell migration in response to chemokines . Immunol. Rev. 177:2000;217-235.
-
(2000)
Immunol. Rev.
, vol.177
, pp. 217-235
-
-
Sotsios, Y.1
Ward, S.G.2
-
4
-
-
0034911881
-
Synthesis and function of 3-phosphorylated inositol lipids
-
Vanhaesebroeck B., Leevers S.J., Ahmadi K., Timms J., Katso R., Driscoll P.C., Woscholski R., Parker P.J., Waterfield M.D. Synthesis and function of 3-phosphorylated inositol lipids. Annu. Rev. Biochem. 70:2001;535-602.
-
(2001)
Annu. Rev. Biochem.
, vol.70
, pp. 535-602
-
-
Vanhaesebroeck, B.1
Leevers, S.J.2
Ahmadi, K.3
Timms, J.4
Katso, R.5
Driscoll, P.C.6
Woscholski, R.7
Parker, P.J.8
Waterfield, M.D.9
-
5
-
-
0036532121
-
Roles of PI3Ks in leukocyte chemotaxis and phagocytosis
-
Stephens L., Ellson C., Hawkins P. Roles of PI3Ks in leukocyte chemotaxis and phagocytosis. Curr. Opin. Cell Biol. 14:2002;203-213.
-
(2002)
Curr. Opin. Cell Biol.
, vol.14
, pp. 203-213
-
-
Stephens, L.1
Ellson, C.2
Hawkins, P.3
-
6
-
-
0033560747
-
Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium
-
Meili R., Ellsworth C., Lee S., Reddy T.B., Ma H., Firtel R.A. Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium. EMBO J. 18:1999;2092-2105.
-
(1999)
EMBO J.
, vol.18
, pp. 2092-2105
-
-
Meili, R.1
Ellsworth, C.2
Lee, S.3
Reddy, T.B.4
Ma, H.5
Firtel, R.A.6
-
7
-
-
0032475863
-
G protein signaling events are activated at the leading edge of chemotactic cells
-
Parent C.A., Blacklock B.J., Froehlich W.M., Murphy D.B., Devreotes P.N. G protein signaling events are activated at the leading edge of chemotactic cells. Cell. 95:1998;81-91.
-
(1998)
Cell
, vol.95
, pp. 81-91
-
-
Parent, C.A.1
Blacklock, B.J.2
Froehlich, W.M.3
Murphy, D.B.4
Devreotes, P.N.5
-
8
-
-
0034332904
-
Leukocytes navigate by compass: Roles of PI3Kγ and its lipid products
-
Rickert P., Weiner O.D., Wang F., Bourne H.R., Servant G. Leukocytes navigate by compass roles of PI3Kγ and its lipid products . Trends Cell Biol. 10:2000;466-473.
-
(2000)
Trends Cell Biol.
, vol.10
, pp. 466-473
-
-
Rickert, P.1
Weiner, O.D.2
Wang, F.3
Bourne, H.R.4
Servant, G.5
-
9
-
-
0037205266
-
PI 3-kinases and PTEN. How opposites chemoattract
-
Comer F.I., Parent C.A. PI 3-kinases and PTEN. How opposites chemoattract. Cell. 109:2002;541-544.
-
(2002)
Cell
, vol.109
, pp. 541-544
-
-
Comer, F.I.1
Parent, C.A.2
-
10
-
-
0033128166
-
Distinct PI(3)Ks mediate mitogenic signalling and cell migration in macrophages
-
Vanhaesebroeck B., Jones G.E., Allen W.E., Zicha D., Hooshmand-Rad R., Sawyer C., Wells C., Waterfield M.D., Ridley A.J. Distinct PI(3)Ks mediate mitogenic signalling and cell migration in macrophages. Nat. Cell Biol. 1:1999;69-71.
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 69-71
-
-
Vanhaesebroeck, B.1
Jones, G.E.2
Allen, W.E.3
Zicha, D.4
Hooshmand-Rad, R.5
Sawyer, C.6
Wells, C.7
Waterfield, M.D.8
Ridley, A.J.9
-
11
-
-
0037205265
-
Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis
-
Funamoto S., Meili R., Lee S., Parry L., Firtel R.A. Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis. Cell. 109:2002;611-623.
-
(2002)
Cell
, vol.109
, pp. 611-623
-
-
Funamoto, S.1
Meili, R.2
Lee, S.3
Parry, L.4
Firtel, R.A.5
-
12
-
-
0037205230
-
Tumor suppressor PTEN mediates sensing of chemoattractant gradients
-
Lijima M., Devreotes P. Tumor suppressor PTEN mediates sensing of chemoattractant gradients. Cell. 109:2002;599-610.
-
(2002)
Cell
, vol.109
, pp. 599-610
-
-
Lijima, M.1
Devreotes, P.2
-
13
-
-
0343183328
-
Genetic deletion of the Pten tumor suppressor gene promotes cell motility by activation of Rac1 and Cdc42 GTPases
-
Liliental J., Moon S.Y., Lesche R., Mamillapalli R., Li D., Zheng Y., Sun H., Wu H. Genetic deletion of the Pten tumor suppressor gene promotes cell motility by activation of Rac1 and Cdc42 GTPases. Curr. Biol. 10:2000;401-404.
-
(2000)
Curr. Biol.
, vol.10
, pp. 401-404
-
-
Liliental, J.1
Moon, S.Y.2
Lesche, R.3
Mamillapalli, R.4
Li, D.5
Zheng, Y.6
Sun, H.7
Wu, H.8
-
14
-
-
0037155727
-
P-Rex1, a PtdIns(3,4,5)P3- and Gβγ-regulated guanine-nucleotide exchange factor for Rac
-
Welch H.C., Coadwell W.J., Ellson C.D., Ferguson G.J., Andrews S.R., Erdjument-Bromage H., Tempst P., Hawkins P.T., Stephens L.R. P-Rex1, a PtdIns(3,4,5)P3- and Gβγ-regulated guanine-nucleotide exchange factor for Rac. Cell. 108:2002;809-821.
-
(2002)
Cell
, vol.108
, pp. 809-821
-
-
Welch, H.C.1
Coadwell, W.J.2
Ellson, C.D.3
Ferguson, G.J.4
Andrews, S.R.5
Erdjument-Bromage, H.6
Tempst, P.7
Hawkins, P.T.8
Stephens, L.R.9
-
15
-
-
0036308972
-
A PtdInsP(3)- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity
-
Weiner O.D., Neilsen P.O., Prestwich G.D., Kirschner M.W., Cantley L.C., Bourne H.R. A PtdInsP(3)- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity. Nat. Cell Biol. 4:2002;509-513.
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 509-513
-
-
Weiner, O.D.1
Neilsen, P.O.2
Prestwich, G.D.3
Kirschner, M.W.4
Cantley, L.C.5
Bourne, H.R.6
-
16
-
-
0026608462
-
Tyr721 regulates specific binding of the CSF-1 receptor kinase insert to PI 3′-kinase SH2 domains: A model for SH2-mediated receptor-target interactions
-
Reedijk M., Liu X., van der Geer P., Letwin K., Waterfield M.D., Hunter T., Pawson T. Tyr721 regulates specific binding of the CSF-1 receptor kinase insert to PI 3′-kinase SH2 domains a model for SH2-mediated receptor-target interactions . EMBO J. 11:1992;1365-1372.
-
(1992)
EMBO J.
, vol.11
, pp. 1365-1372
-
-
Reedijk, M.1
Liu, X.2
Van Der Geer, P.3
Letwin, K.4
Waterfield, M.D.5
Hunter, T.6
Pawson, T.7
-
17
-
-
0033546148
-
Characterizing the interactions between the two subunits of the p101/p110γ phosphoinositide 3-kinase and their role in the activation of this enzyme by G βγ subunits
-
Krugmann S., Hawkins P.T., Pryer N., Braselmann S. Characterizing the interactions between the two subunits of the p101/p110γ phosphoinositide 3-kinase and their role in the activation of this enzyme by G βγ subunits. J. Biol. Chem. 274:1999;17152-17158.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 17152-17158
-
-
Krugmann, S.1
Hawkins, P.T.2
Pryer, N.3
Braselmann, S.4
-
18
-
-
0034635452
-
Central role for G protein-coupled phosphoinositide 3-kinase γ in inflammation
-
Hirsch E., Katanaev V.L., Garlanda C., Azzolino O., Pirola L., Silengo L., Sozzani S., Mantovani A., Altruda F., Wymann M.P. Central role for G protein-coupled phosphoinositide 3-kinase γ in inflammation. Science. 287:2000;1049-1053.
-
(2000)
Science
, vol.287
, pp. 1049-1053
-
-
Hirsch, E.1
Katanaev, V.L.2
Garlanda, C.3
Azzolino, O.4
Pirola, L.5
Silengo, L.6
Sozzani, S.7
Mantovani, A.8
Altruda, F.9
Wymann, M.P.10
-
19
-
-
0034635264
-
Function of P13Kγ in thymocyte development, T cell activation, and neutrophil migration
-
Sasaki T., Irie-Sasaki J., Jones R.G., Oliveira-dos-Santos A.J., Stanford W.L., Bolon B., Wakeham A., Itie A., Bouchard D., Kozieradzki I., Joza N., Mak T.W., Ohashi P.S., Suzuki A., Penninger J.M. Function of P13Kγ in thymocyte development, T cell activation, and neutrophil migration. Science. 287:2000;1040-1046.
-
(2000)
Science
, vol.287
, pp. 1040-1046
-
-
Sasaki, T.1
Irie-Sasaki, J.2
Jones, R.G.3
Oliveira-dos-Santos, A.J.4
Stanford, W.L.5
Bolon, B.6
Wakeham, A.7
Itie, A.8
Bouchard, D.9
Kozieradzki, I.10
Joza, N.11
Mak, T.W.12
Ohashi, P.S.13
Suzuki, A.14
Penninger, J.M.15
-
20
-
-
0034635221
-
Roles of PLC-β2 and -β3 and P13Kγ in chemoattractant-mediated signal transduction
-
Li Z., Jiang H., Xie W., Zhang Z., Smreka A.V., Wu D. Roles of PLC-β2 and -β3 and P13Kγ in chemoattractant-mediated signal transduction. Science. 287:2000;1046-1049.
-
(2000)
Science
, vol.287
, pp. 1046-1049
-
-
Li, Z.1
Jiang, H.2
Xie, W.3
Zhang, Z.4
Smreka, A.V.5
Wu, D.6
-
21
-
-
0033781348
-
Rho GTPases and cell migration: Measurement of macrophage chemotaxis
-
Jones G.E., Ridley A.J., Zicha D. Rho GTPases and cell migration measurement of macrophage chemotaxis . Methods Enzymol. 325:2000;449-462.
-
(2000)
Methods Enzymol.
, vol.325
, pp. 449-462
-
-
Jones, G.E.1
Ridley, A.J.2
Zicha, D.3
-
23
-
-
0034080318
-
The biology of chemokines and their receptors
-
Rossi D., Zlotnik A. The biology of chemokines and their receptors. Annu. Rev. Immunol. 18:2000;217-242.
-
(2000)
Annu. Rev. Immunol.
, vol.18
, pp. 217-242
-
-
Rossi, D.1
Zlotnik, A.2
-
24
-
-
0034144269
-
Chemokines: A new classification system and their role in immunity
-
Zlotnik A., Yoshie O. Chemokines a new classification system and their role in immunity . Immunity. 12:2000;121-127.
-
(2000)
Immunity
, vol.12
, pp. 121-127
-
-
Zlotnik, A.1
Yoshie, O.2
-
25
-
-
0035128074
-
Requirement for Rho GTPases and PI 3-kinases during apoptotic cell phagocytosis by macrophages
-
Leverrier Y., Ridley A.J. Requirement for Rho GTPases and PI 3-kinases during apoptotic cell phagocytosis by macrophages. Curr. Biol. 11:2001;195-199.
-
(2001)
Curr. Biol.
, vol.11
, pp. 195-199
-
-
Leverrier, Y.1
Ridley, A.J.2
-
26
-
-
0019499813
-
Expression of the macrophage-specific antigen F4/80 during differentiation of mouse bone marrow cells in culture
-
Hirsch S., Austyn J.M., Gordon S. Expression of the macrophage-specific antigen F4/80 during differentiation of mouse bone marrow cells in culture. J. Exp. Med. 154:1981;713-725.
-
(1981)
J. Exp. Med.
, vol.154
, pp. 713-725
-
-
Hirsch, S.1
Austyn, J.M.2
Gordon, S.3
-
27
-
-
0019784850
-
F4/80, a monoclonal antibody directed specifically against the mouse macrophage
-
Austyn J.M., Gordon S. F4/80, a monoclonal antibody directed specifically against the mouse macrophage. Eur. J. Immunol. 11:1981;805-815.
-
(1981)
Eur. J. Immunol.
, vol.11
, pp. 805-815
-
-
Austyn, J.M.1
Gordon, S.2
-
29
-
-
0021981585
-
The regulation of mononuclear phagocyte entry into S phase by the colony stimulating factor CSF-1
-
Tushinski R.J., Stanley E.R. The regulation of mononuclear phagocyte entry into S phase by the colony stimulating factor CSF-1. J. Cell Physiol. 122:1985;221-228.
-
(1985)
J. Cell Physiol.
, vol.122
, pp. 221-228
-
-
Tushinski, R.J.1
Stanley, E.R.2
-
30
-
-
0031827415
-
Update on the biologic effects of macrophage colony-stimulating factor
-
Flanagan A.M., Lader C.S. Update on the biologic effects of macrophage colony-stimulating factor. Curr. Opin. Hematol. 5:1998;181-185.
-
(1998)
Curr. Opin. Hematol.
, vol.5
, pp. 181-185
-
-
Flanagan, A.M.1
Lader, C.S.2
-
31
-
-
0024361531
-
Colony-stimulating factor-1 induces rapid behavioural responses in the mouse macrophage cell line, BAC1.2F5
-
Boocock C.A., Jones G.E., Stanley E.R., Pollard J.W. Colony-stimulating factor-1 induces rapid behavioural responses in the mouse macrophage cell line, BAC1.2F5. J. Cell Sci. 93:1989;447-456.
-
(1989)
J. Cell Sci.
, vol.93
, pp. 447-456
-
-
Boocock, C.A.1
Jones, G.E.2
Stanley, E.R.3
Pollard, J.W.4
-
32
-
-
0029924145
-
Direct observation and quantification of macrophage chemoattraction to the growth factor CSF-1
-
Webb S.E., Pollard J.W., Jones G.E. Direct observation and quantification of macrophage chemoattraction to the growth factor CSF-1. J. Cell Sci. 109:1996;793-803.
-
(1996)
J. Cell Sci.
, vol.109
, pp. 793-803
-
-
Webb, S.E.1
Pollard, J.W.2
Jones, G.E.3
-
33
-
-
0030940218
-
Rho, Rac and Cdc42 regulate actin organization and cell adhesion in macrophages
-
Allen W.E., Jones G.E., Pollard J.W., Ridley A.J. Rho, Rac and Cdc42 regulate actin organization and cell adhesion in macrophages. J. Cell Sci. 110:1997;707-720.
-
(1997)
J. Cell Sci.
, vol.110
, pp. 707-720
-
-
Allen, W.E.1
Jones, G.E.2
Pollard, J.W.3
Ridley, A.J.4
-
34
-
-
0032528851
-
Lysophosphatidic acid is a major serum noncytokine survival factor for murine macrophages which acts via the phosphatidylinositol 3-kinase signaling pathway
-
Koh J.S., Lieberthal W., Heydrick S., Levine J.S. Lysophosphatidic acid is a major serum noncytokine survival factor for murine macrophages which acts via the phosphatidylinositol 3-kinase signaling pathway. J. Clin. Invest. 102:1998;716-727.
-
(1998)
J. Clin. Invest.
, vol.102
, pp. 716-727
-
-
Koh, J.S.1
Lieberthal, W.2
Heydrick, S.3
Levine, J.S.4
-
35
-
-
0037133606
-
Neutrophils lacking phosphoinositide 3-kinase γ show loss of directionality during N-formyl-Met-Leu-Phe-induced chemotaxis
-
Hannigan M., Zhan L., Li Z., Ai Y., Wu D., Huang C.K. Neutrophils lacking phosphoinositide 3-kinase γ show loss of directionality during N-formyl-Met-Leu-Phe-induced chemotaxis. Proc. Natl. Acad. Sci. USA. 99:2002;3603-3608.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 3603-3608
-
-
Hannigan, M.1
Zhan, L.2
Li, Z.3
Ai, Y.4
Wu, D.5
Huang, C.K.6
-
36
-
-
0033179473
-
Regulation of p21rac activation in human neutrophils
-
Geijsen N., van Delft S., Raaijmakers J.A., Lammers J.W., Collard J.G., Koenderman L., Coffer P.J. Regulation of p21rac activation in human neutrophils. Blood. 94:1999;1121-1130.
-
(1999)
Blood
, vol.94
, pp. 1121-1130
-
-
Geijsen, N.1
Van Delft, S.2
Raaijmakers, J.A.3
Lammers, J.W.4
Collard, J.G.5
Koenderman, L.6
Coffer, P.J.7
-
37
-
-
0036308458
-
Lipid products of PI(3)Ks maintain persistent cell polarity and directed motility in neutrophils
-
Wang F., Herzmark P., Weiner O.D., Srinivasan S., Servant G., Bourne H.R. Lipid products of PI(3)Ks maintain persistent cell polarity and directed motility in neutrophils. Nat. Cell Biol. 4:2002;513-518.
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 513-518
-
-
Wang, F.1
Herzmark, P.2
Weiner, O.D.3
Srinivasan, S.4
Servant, G.5
Bourne, H.R.6
-
38
-
-
0033580822
-
Phosphoinositide 3-kinase-dependent and -independent activation of the small GTPase Rac2 in human neutrophils
-
Akasaki T., Koga H., Sumimoto H. Phosphoinositide 3-kinase-dependent and -independent activation of the small GTPase Rac2 in human neutrophils. J. Biol. Chem. 274:1999;18055-18059.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 18055-18059
-
-
Akasaki, T.1
Koga, H.2
Sumimoto, H.3
-
39
-
-
0037415640
-
Rac and Cdc42 play distinct roles in regulating PI(3,4,5)P3 and polarity during neutrophil chemotaxis
-
Srinivasan S., Wang F., Glavas S., Ott A., Hofmann F., Aktories K., Kalman D., Bourne H.R. Rac and Cdc42 play distinct roles in regulating PI(3,4,5)P3 and polarity during neutrophil chemotaxis. J. Cell Biol. 160:2003;375-385.
-
(2003)
J. Cell Biol.
, vol.160
, pp. 375-385
-
-
Srinivasan, S.1
Wang, F.2
Glavas, S.3
Ott, A.4
Hofmann, F.5
Aktories, K.6
Kalman, D.7
Bourne, H.R.8
-
40
-
-
0036672791
-
The CDM protein DOCK2 in lymphocyte migration
-
Reif K., Cyster J.G. The CDM protein DOCK2 in lymphocyte migration. Trends Cell Biol. 12:2002;368-373.
-
(2002)
Trends Cell Biol.
, vol.12
, pp. 368-373
-
-
Reif, K.1
Cyster, J.G.2
-
41
-
-
0035793866
-
Role of the sphingosine-1-phosphate receptor EDG-1 in PDGF-induced cell motility
-
Hobson J.P., Rosenfeldt H.M., Barak L.S., Olivera A., Poulton S., Caron M.G., Milstien S., Spiegel S. Role of the sphingosine-1-phosphate receptor EDG-1 in PDGF-induced cell motility. Science. 291:2001;1800-1803.
-
(2001)
Science
, vol.291
, pp. 1800-1803
-
-
Hobson, J.P.1
Rosenfeldt, H.M.2
Barak, L.S.3
Olivera, A.4
Poulton, S.5
Caron, M.G.6
Milstien, S.7
Spiegel, S.8
-
42
-
-
0035090647
-
A role for chemokine receptor transactivation in growth factor signaling
-
Mira E., Lacalle R.A., Gonzalez M.A., Gomez-Mouton C., Abad J.L., Bernad A., Martinez A.C., Manes S. A role for chemokine receptor transactivation in growth factor signaling. EMBO Rep. 2:2001;151-156.
-
(2001)
EMBO Rep.
, vol.2
, pp. 151-156
-
-
Mira, E.1
Lacalle, R.A.2
Gonzalez, M.A.3
Gomez-Mouton, C.4
Abad, J.L.5
Bernad, A.6
Martinez, A.C.7
Manes, S.8
|