Engineering of a target site-specific recombinase by a combined evolution-and structure-guided approach

Nucleic Acids Research

Volumn 41, Issue 4, 2013, Pages 2394-2403

  Abi Ghanem, Josephine ^a   Chusainow, Janet ^a,b   Karimova, Madina ^a,b   Spiegel, Christopher ^a,b   Hofmann Sieber, Helga ^c   Hauber, Joachim ^c   Buchholz, Frank ^a,b   Pisabarro, M Teresa ^a  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^b MAX PLANCK INSTITUTE OF MOLECULAR CELL BIOLOGY AND GENETICS   (Germany)

^c LEIBNIZ INSTITUTE FOR EXPERIMENTAL VIROLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

RECOMBINASE;

ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DNA RECOMBINATION; ENZYME ACTIVITY; ENZYME ENGINEERING; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; GENE SEQUENCE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; MOLECULAR DYNAMICS; MOLECULAR EVOLUTION; MOLECULAR MODEL; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; VIRUS GENOME;

ATTACHMENT SITES, MICROBIOLOGICAL; DIRECTED MOLECULAR EVOLUTION; DNA; MODELS, MOLECULAR; PROTEIN BINDING; RECOMBINASES;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 84876397726     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gks1308     Document Type: Article

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