-
1
-
-
53049110571
-
Effect of n-3 polyunsaturated fatty acids in patients with chronic heart failure (the GISSI-HF trial): A randomised, double-blind, placebo-controlled trial
-
and Gissi-HF Investigators
-
Tavazzi L, Maggioni AP, Marchioli R, et al and Gissi-HF Investigators. Effect of n-3 polyunsaturated fatty acids in patients with chronic heart failure (the GISSI-HF trial): A randomised, double-blind, placebo-controlled trial. Lancet. 2008;372:1223-1230
-
(2008)
Lancet
, vol.372
, pp. 1223-1230
-
-
Tavazzi, L.1
Maggioni, A.P.2
Marchioli, R.3
-
2
-
-
78549233384
-
Alpha Omega Trial Group. n-3 fatty acids and cardiovascular events after myocardial infarction
-
Kromhout D, Giltay EJ, Jm G, et al; and Alpha Omega Trial Group. n-3 fatty acids and cardiovascular events after myocardial infarction. N Engl J Med. 2010;363:2015-2026
-
(2010)
N Engl J Med
, Issue.363
, pp. 2015-2026
-
-
Kromhout, D.1
Giltay, E.J.2
Jm, G.3
-
3
-
-
0037161373
-
Early protection against sudden death by n-3 polyunsaturated fatty acids after myocardial infarction: Time-course analysis of the results of the Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico (GISSI)-Prevenzione
-
GISSI-Prevenzione Investigators
-
Marchioli R, Barzi F, Bomba E; and GISSI-Prevenzione Investigators. Early protection against sudden death by n-3 polyunsaturated fatty acids after myocardial infarction: Time-course analysis of the results of the Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico (GISSI)-Prevenzione. Circulation. 2002;105:1897-1903
-
(2002)
Circulation
, vol.105
, pp. 1897-1903
-
-
Marchioli, R.1
Barzi, F.2
Bomba, E3
.4
-
4
-
-
79951670918
-
Omega-3 fatty acids prevent pressure overload-induced cardiac fibrosis through activation of cyclic GMP/protein kinase G signaling in cardiac fibroblasts
-
Chen J, Shearer GC, Chen Q, et al. Omega-3 fatty acids prevent pressure overload-induced cardiac fibrosis through activation of cyclic GMP/protein kinase G signaling in cardiac fibroblasts. Circulation. 2011;123:584-593
-
(2011)
Circulation
, Issue.123
, pp. 584-593
-
-
Chen, J.1
Shearer, G.C.2
Chen, Q.3
-
5
-
-
36649034268
-
Dietary supplementation with omega-3 PUFA increases adiponectin and attenuates ventricular remodeling and dysfunction with pressure overload
-
Duda MK, O'Shea KM, Lei B, et al. Dietary supplementation with omega-3 PUFA increases adiponectin and attenuates ventricular remodeling and dysfunction with pressure overload. Cardiovasc Res. 2007;76: 303-310
-
(2007)
Cardiovasc Res
, vol.76
, pp. 303-310
-
-
Duda, M.K.1
O'Shea, K.M.2
Lei, B.3
-
6
-
-
0030897717
-
N-3 fatty acids and urinary excretion of nitric oxide metabolites in humans
-
Harris WS, Rambjør GS, Windsor SL, et al. n-3 fatty acids and urinary excretion of nitric oxide metabolites in humans. Am J Clin Nutr. 1997;65: 459-464
-
(1997)
Am J Clin Nutr
, vol.65
, pp. 459-464
-
-
Harris, W.S.1
Rambjør, G.S.2
Windsor, S.L.3
-
7
-
-
0038700514
-
Prevention of sudden cardiac death by n-3 polyunsaturated fatty acids
-
Leaf A, Xiao YF, Kang JX, et al. Prevention of sudden cardiac death by n-3 polyunsaturated fatty acids. Pharmacol Ther. 2003;98:355-377
-
(2003)
Pharmacol Ther
, vol.98
, pp. 355-377
-
-
Leaf, A.1
Xiao, Y.F.2
Kang, J.X.3
-
8
-
-
70349413038
-
Suppressive effect of EPA on the incidence of coronary events in hypercholesterolemia with impaired glucose metabolism: Sub-analysis of the Japan EPA Lipid Intervention Study (JELIS)
-
and JELIS Investigators Japan
-
Oikawa S, Yokoyama M, Origasa H, et al; and JELIS Investigators Japan. Suppressive effect of EPA on the incidence of coronary events in hypercholesterolemia with impaired glucose metabolism: Sub-analysis of the Japan EPA Lipid Intervention Study (JELIS). Atherosclerosis. 2009;206: 535-539
-
(2009)
Atherosclerosis
, vol.206
, pp. 535-539
-
-
Oikawa, S.1
Yokoyama, M.2
Origasa, H.3
-
9
-
-
34347352169
-
Diabetic cardiomyopathy revisted
-
Boudina S, Abel ED. Diabetic cardiomyopathy revisted. Circulation. 2007;115:3213-3223
-
(2007)
Circulation
, vol.115
, pp. 3213-3223
-
-
Boudina, S.1
Abel, E.D.2
-
10
-
-
0037417725
-
A critical role for PPARalphamediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: Modulation by dietary fat content
-
Finck BN, Han X, Courtois M, et al. A critical role for PPARalphamediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: Modulation by dietary fat content. Proc Natl Acad Sci U S A. 2003; 100:1226-1231
-
(2003)
Proc Natl Acad Sci U S A.
, vol.100
, pp. 1226-1231
-
-
Finck, B.N.1
Han, X.2
Courtois, M.3
-
11
-
-
0035061419
-
A novel mouse model of lipotoxic cardiomyopathy
-
Chiu HC, Kovacs A, Ford DA, et al. A novel mouse model of lipotoxic cardiomyopathy. J Clin Invest. 2001;107:813-822
-
(2001)
J Clin Invest
, vol.107
, pp. 813-822
-
-
Chiu, H.C.1
Kovacs, A.2
Ford, D.A.3
-
12
-
-
34948910262
-
Cardiomyocyte expression of PPARgamma leads to cardiac dysfunction in mice
-
Son NH, Park TS, Yamashita H, et al. Cardiomyocyte expression of PPARgamma leads to cardiac dysfunction in mice. J Clin Invest. 2007; 117:2791-2801
-
(2007)
J Clin Invest
, vol.117
, pp. 2791-2801
-
-
Son, N.H.1
Park, T.S.2
Yamashita, H.3
-
13
-
-
70350349875
-
Myocardial lipid accumulation in patients with pressure-overloaded heart and metabolic syndrome
-
Marfella R, Di Filippo C, Portoghese M, et al. Myocardial lipid accumulation in patients with pressure-overloaded heart and metabolic syndrome. J Lipid Res. 2009;50:2314-2323
-
(2009)
J Lipid Res
, vol.50
, pp. 2314-2323
-
-
Marfella, R.1
Di Filippo, C.2
Portoghese, M.3
-
14
-
-
84862927069
-
Chronic maternal protein deprivation in mice is associated with overexpression of the cohesin-mediator complex in liver of their offspring
-
Balasa A, Sanchez-Valle A, Sadikovic B, et al. Chronic maternal protein deprivation in mice is associated with overexpression of the cohesin-mediator complex in liver of their offspring. J Nutr. 2011; 141:2106-2112
-
(2011)
J Nutr
, Issue.141
, pp. 2106-2112
-
-
Balasa, A.1
Sanchez-Valle, A.2
Sadikovic, B.3
-
16
-
-
70449158340
-
A simple method for the isolation and purification of total lipides from animal tissues
-
Folch J, Lees M, Sloane Stanley GH. A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem. 1957; 226:497-509
-
(1957)
J Biol Chem
, vol.226
, pp. 497-509
-
-
Folch, J.1
Lees, M.2
Sloane Stanley, G.H.3
-
17
-
-
0037184925
-
Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle
-
Yu C, Chen Y, Cline GW, et al. Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle. J Biol Chem. 2002;277: 50230-50236
-
(2002)
J Biol Chem
, vol.277
, pp. 50230-50236
-
-
Yu, C.1
Chen, Y.2
Cline, G.W.3
-
18
-
-
74949097878
-
Comprehensive quantitative analysis of bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry
-
Bielawski J, Pierce JS, Snider J, et al. Comprehensive quantitative analysis of bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry. Methods Mol Biol. 2009;579:443-467
-
(2009)
Methods Mol Biol
, vol.579
, pp. 443-467
-
-
Bielawski, J.1
Pierce, J.S.2
Snider, J.3
-
19
-
-
77957846150
-
PPARg-induced cardiolipotoxicity in mice is ameliorated by PPARa deficiency despite increases in fatty acid oxidation
-
Son NH, Yu S, Tuinei J, et al. PPARg-induced cardiolipotoxicity in mice is ameliorated by PPARa deficiency despite increases in fatty acid oxidation. J Clin Invest. 2010;120:3443-3454
-
(2010)
J Clin Invest
, Issue.120
, pp. 3443-3454
-
-
Son, N.H.1
Yu, S.2
Tuinei, J.3
-
20
-
-
20644456260
-
Novel cell lines derived from adult human ventricular cardiomyocytes
-
Davidson MM, Nesti C, Palenzuela L, et al. Novel cell lines derived from adult human ventricular cardiomyocytes. J Mol Cell Cardiol 2005;39: 133-47
-
(2005)
J Mol Cell Cardiol
, vol.39
, pp. 133-147
-
-
Davidson, M.M.1
Nesti, C.2
Palenzuela, L.3
-
21
-
-
68349119096
-
The PDE1A-PKCalpha signaling pathway is involved in the upregulation of alpha-smooth muscle actin by TGF-beta1 in adventitial fibroblasts
-
Zhou HY, Chen WD, Zhu DL, et al. The PDE1A-PKCalpha signaling pathway is involved in the upregulation of alpha-smooth muscle actin by TGF-beta1 in adventitial fibroblasts. J Vasc Res. 2010;47:9-15
-
(2010)
J Vasc Res
, Issue.47
, pp. 9-15
-
-
Zhou, H.Y.1
Chen, W.D.2
Zhu, D.L.3
-
22
-
-
84864219466
-
N-3 fatty acids and cardiovascular outcomes in patients with dysglycemia
-
and ORIGIN Trial Investigators
-
Bosch J, Gerstein HC, Dagenais GR, et al; and ORIGIN Trial Investigators. n-3 fatty acids and cardiovascular outcomes in patients with dysglycemia. N Engl J Med. 2012;367:309-318
-
(2012)
N Engl J Med
, Issue.367
, pp. 309-318
-
-
Bosch, J.1
Gerstein, H.C.2
Dagenais, G.R.3
-
23
-
-
84866070612
-
Association between omega-3 fatty acid supplementation and risk of major cardiovascular disease events: A systematic review and meta-analysis
-
Rizos EC, Ntzani EE, Bika E, et al. Association between omega-3 fatty acid supplementation and risk of major cardiovascular disease events: A systematic review and meta-analysis. JAMA. 2012;308:1024-1033
-
(2012)
JAMA
, Issue.308
, pp. 1024-1033
-
-
Rizos, E.C.1
Ntzani, E.E.2
Bika, E.3
-
24
-
-
26444611189
-
Dietary fish oil attenuates cardiac hypertrophy in lipotoxic cardiomyopathy due to systemic carnitine deficiency
-
Takahashi R, Okumura K, Asai T, et al. Dietary fish oil attenuates cardiac hypertrophy in lipotoxic cardiomyopathy due to systemic carnitine deficiency. Cardiovasc Res. 2005;68:213-223
-
(2005)
Cardiovasc Res
, vol.68
, pp. 213-223
-
-
Takahashi, R.1
Okumura, K.2
Asai, T.3
-
25
-
-
58449105597
-
Fish oil, but not flaxseed oil, decreases inflammation and prevents pressure overload-induced cardiac dysfunction
-
Duda MK, O'Shea KM, Tintinu A, et al. Fish oil, but not flaxseed oil, decreases inflammation and prevents pressure overload-induced cardiac dysfunction. Cardiovasc Res. 2009;81:319-327
-
(2009)
Cardiovasc Res
, vol.81
, pp. 319-327
-
-
Duda, M.K.1
O'Shea, K.M.2
Tintinu, A.3
-
26
-
-
38549089487
-
Dietary n-3 polyunsaturated fatty acids and direct renin inhibition improve electrical remodeling in a model of high human renin hypertension
-
Fischer R, Dechend R, Qadri F, et al. Dietary n-3 polyunsaturated fatty acids and direct renin inhibition improve electrical remodeling in a model of high human renin hypertension. Hypertension. 2008;51:540-546
-
(2008)
Hypertension
, vol.51
, pp. 540-546
-
-
Fischer, R.1
Dechend, R.2
Qadri, F.3
-
27
-
-
27744590874
-
Long-term intake of edible oils benefits blood pressure and myocardial structure in spontaneously hypertensive rat (SHR) and streptozotocin diabetic SHR
-
Medeiros FJ, Mothe CG, Aguila MB, et al. Long-term intake of edible oils benefits blood pressure and myocardial structure in spontaneously hypertensive rat (SHR) and streptozotocin diabetic SHR. Prostaglandins Other Lipid Mediat. 2005;78:231-248
-
(2005)
Prostaglandins Other Lipid Mediat
, vol.78
, pp. 231-248
-
-
Medeiros, F.J.1
Mothe, C.G.2
Aguila, M.B.3
-
28
-
-
0026489335
-
Preferential elevation of protein kinase C isoform beta II and diacylglycerol levels in the aorta and heart of diabetic rats: Differential reversibility to glycemic control by islet cell transplantation
-
Inoguchi T, Battan R, Handler E, et al. Preferential elevation of protein kinase C isoform beta II and diacylglycerol levels in the aorta and heart of diabetic rats: Differential reversibility to glycemic control by islet cell transplantation. Proc Natl Acad Sci U S A. 1992;89:11059-11063
-
(1992)
Proc Natl Acad Sci U S A.
, vol.89
, pp. 11059-11063
-
-
Inoguchi, T.1
Battan, R.2
Handler, E.3
-
29
-
-
76649123086
-
Rescue of cardiomyopathy in peroxisome proliferator-activated receptor-alpha transgenic mice by deletion of lipoprotein lipase identifies sources of cardiac lipids and peroxisome proliferator-activated receptor-alpha activators
-
Duncan JG, Bharadwaj KG, Fong JL, et al. Rescue of cardiomyopathy in peroxisome proliferator-activated receptor-alpha transgenic mice by deletion of lipoprotein lipase identifies sources of cardiac lipids and peroxisome proliferator-activated receptor-alpha activators. Circulation. 2010; 121:426-435
-
(2010)
Circulation
, Issue.121
, pp. 426-435
-
-
Duncan, J.G.1
Bharadwaj, K.G.2
Fong, J.L.3
-
30
-
-
4544252278
-
Hyperleptinemia prevents lipotoxic cardiomyopathy in acyl CoA synthase transgenic mice
-
Lee Y, Naseem RH, Duplomb L, et al. Hyperleptinemia prevents lipotoxic cardiomyopathy in acyl CoA synthase transgenic mice. Proc Natl Acad Sci U S A. 2004;101:13624-13629
-
(2004)
Proc Natl Acad Sci U S A.
, vol.101
, pp. 13624-13629
-
-
Lee, Y.1
Naseem, R.H.2
Duplomb, L.3
-
31
-
-
44949129189
-
Dietary fish oil reverses lipotoxicity, altered glucose metabolism, and nPKCepsilon translocation in the heart of dyslipemic insulin-resistant rats
-
D'Alessandro ME, Chicco A, Lombardo YB. Dietary fish oil reverses lipotoxicity, altered glucose metabolism, and nPKCepsilon translocation in the heart of dyslipemic insulin-resistant rats. Metabolism. 2008;57: 911-919
-
(2008)
Metabolism
, vol.57
, pp. 911-919
-
-
D'Alessandro, M.E.1
Chicco, A.2
Lombardo, Y.B.3
-
32
-
-
0032189981
-
Phospholipid source and molecular species composition of 1,2-diacylglycerol in agonist-stimulated rat cardiomyocytes
-
Eskildsen-Helmond YE, Hahnel D, Reinhardt U, et al. Phospholipid source and molecular species composition of 1,2-diacylglycerol in agonist-stimulated rat cardiomyocytes. Cardiovasc Res. 1998;40:182-190
-
(1998)
Cardiovasc Res
, vol.40
, pp. 182-190
-
-
Eskildsen-Helmond, Y.E.1
Hahnel, D.2
Reinhardt, U.3
-
33
-
-
0035204169
-
Implication of acyl chain of diacylglycerols in activation of different isoforms of protein kinase C
-
Madani S, Hichami A, Legrand A, et al. Implication of acyl chain of diacylglycerols in activation of different isoforms of protein kinase C. FASEB J. 2001;15:2595-2601
-
(2001)
FASEB J.
, vol.15
, pp. 2595-2601
-
-
Madani, S.1
Hichami, A.2
Legrand, A.3
-
34
-
-
26244440432
-
Diacylglycerol-containing docosahexaenoic acid in acyl chain modulates airway smooth muscle tone
-
Hichami A, Morin C, Rousseau E, et al. Diacylglycerol-containing docosahexaenoic acid in acyl chain modulates airway smooth muscle tone. Am J Respir Cell Mol Biol. 2005;33:378-386
-
(2005)
Am J Respir Cell Mol Biol
, vol.33
, pp. 378-386
-
-
Hichami, A.1
Morin, C.2
Rousseau, E.3
-
35
-
-
1642388834
-
PKC-alpha regulates cardiac contractility and propensity toward heart failure
-
Braz JC, Gregory K, Pathak A, et al. PKC-alpha regulates cardiac contractility and propensity toward heart failure. Nat Med. 2004;10:248-254
-
(2004)
Nat Med
, vol.10
, pp. 248-254
-
-
Braz, J.C.1
Gregory, K.2
Pathak, A.3
-
36
-
-
0036724631
-
Expression of connective tissue growth factor is increased in injured myocardium associated with protein kinase C beta2 activation and diabetes
-
Way KJ, Isshiki K, Suzuma K, et al. Expression of connective tissue growth factor is increased in injured myocardium associated with protein kinase C beta2 activation and diabetes. Diabetes. 2002;51:2709-2718
-
(2002)
Diabetes
, vol.51
, pp. 2709-2718
-
-
Way, K.J.1
Isshiki, K.2
Suzuma, K.3
-
37
-
-
77953654365
-
Inhibition of protein kinase C-beta by ruboxistaurin preserves cardiac function and reduces extracellular matrix production in diabetic cardiomyopathy
-
Connelly KA, Kelly DJ, Zhang Y, et al. Inhibition of protein kinase C-beta by ruboxistaurin preserves cardiac function and reduces extracellular matrix production in diabetic cardiomyopathy. Circ Heart Fail. 2009;2:129-137
-
(2009)
Circ Heart Fail
, vol.2
, pp. 129-137
-
-
Connelly, K.A.1
Kelly, D.J.2
Zhang, Y.3
-
38
-
-
0035116272
-
Inhibitory effects of omega-3 fatty acids on protein kinase C activity in vitro
-
Seung Kim HF, Weeber EJ, Sweatt JD, et al. Inhibitory effects of omega-3 fatty acids on protein kinase C activity in vitro. Mol Psychiatry. 2001;6: 246-248
-
(2001)
Mol Psychiatry
, vol.6
, pp. 246-248
-
-
Seung Kim, H.F.1
Weeber, E.J.2
Sweatt, J.D.3
-
39
-
-
26944448628
-
Protein kinase Cbeta inhibition attenuates osteopontin expression, macrophage recruitment, and tubulointerstitial injury in advanced experimental diabetic nephropathy
-
Kelly DJ, Chanty A, Gow RM, et al. Protein kinase Cbeta inhibition attenuates osteopontin expression, macrophage recruitment, and tubulointerstitial injury in advanced experimental diabetic nephropathy. J Am Soc Nephrol. 2005;16:1654-1660
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 1654-1660
-
-
Kelly, D.J.1
Chanty, A.2
Gow, R.M.3
-
40
-
-
0033865406
-
Osteopontin mediates hypoxia-induced proliferation of cultured mesangial cells: Role of PKC and p38 MAPK
-
Sodhi CP, Batlle D, Sahai A. Osteopontin mediates hypoxia-induced proliferation of cultured mesangial cells: Role of PKC and p38 MAPK. Kidney Int. 2000;58:691-700
-
(2000)
Kidney Int
, vol.58
, pp. 691-700
-
-
Sodhi, C.P.1
Batlle, D.2
Sahai, A.3
-
41
-
-
33846196307
-
Lack of osteopontin improves cardiac function in streptozotocin-induced diabetic mice
-
Subramanian V, Krishnamurthy P, Singh K, et al. Lack of osteopontin improves cardiac function in streptozotocin-induced diabetic mice. Am J Physiol Heart Circ Physiol. 2007;292:673-683
-
(2007)
Am J Physiol Heart Circ Physiol
, vol.292
, pp. 673-683
-
-
Subramanian, V.1
Krishnamurthy, P.2
Singh, K.3
-
42
-
-
34948910262
-
Cardiomyocyte expression of PPARgamma leads to cardiac dysfunction in mice
-
Son NH, Park TS, Yamashita H, et al. Cardiomyocyte expression of PPARgamma leads to cardiac dysfunction in mice. J Clin Invest. 2007; 117:2791-2801
-
(2007)
J Clin Invest
, vol.117
, pp. 2791-2801
-
-
Son, N.H.1
Park, T.S.2
Yamashita, H.3
-
43
-
-
20844440063
-
EPA and DHA reduce LPS-induced inflammation responses in HK-2 cells: Evidence for a PPAR-gamma-dependent mechanism
-
Li H, Ruan XZ, Powis SH, et al. EPA and DHA reduce LPS-induced inflammation responses in HK-2 cells: Evidence for a PPAR-gamma-dependent mechanism. Kidney Int. 2005;67:867-874
-
(2005)
Kidney Int.
, vol.67
, pp. 867-874
-
-
Li, H.1
Ruan, X.Z.2
Powis, S.H.3
|