Prolongation of the QT interval and ventricular tachycardia in patients treated with arsenic trioxide for acute promyelocytic leukemia

Annals of Internal Medicine

Volumn 133, Issue 11, 2000, Pages 881-885

  Ohnishi, K ^a   Yoshida, H ^a   Shigeno, K ^a   Nakamura, S ^a   Fujisawa, S ^a   Naito, K ^a   Shinjo, K ^a   Fujita, Y ^a   Matsui, H ^a   Takeshita, A ^a   Sugiyama, S ^a   Satoh, H ^a   Terada, H ^a   Ohno, R ^a  

^a HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRACYCLINE ANTIBIOTIC AGENT; ARSENIC TRIOXIDE; CYTARABINE; DAUNORUBICIN; ENOCITABINE; IDARUBICIN; LIDOCAINE; MEXILETINE; MITOXANTRONE; RETINOIC ACID; TAMIBAROTENE; UNCLASSIFIED DRUG; VERAPAMIL;

ACUTE MYELOBLASTIC LEUKEMIA; AMBULATORY MONITORING; ARTICLE; CARDIOTOXICITY; CLINICAL ARTICLE; CLINICAL TRIAL; DRUG SAFETY; HEART VENTRICLE TACHYCARDIA; HUMAN; HUMAN CELL; HUMAN TISSUE; PATIENT MONITORING; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; QT INTERVAL; RELAPSE;

EID: 0034610263     PISSN: 00034819     EISSN: None     Source Type: Journal    
DOI: 10.7326/0003-4819-133-11-200012050-00012     Document Type: Article

References (9)

1. Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): II. Clinical efficacy and pharmacokinetics in relapsed patients
2. Complete remission after treatment of acute promyelocytic leukemia with arsenic trioxide
3. Studies on treatment of acute promyelocytic leukemia with arsenic trioxide: Remission induction, follow-up, and molecular monitoring in 11 newly diagnosed and 47 relapsed acute promyelocytic leukemia patients
4. Ventricular fibrillation caused by arsenic poisoning
5. Arsenic-induced atypical ventricular tachycardia
6. Torsade de pointes and T-U wave alternans associated with arsenic poisoning
7. Acute and chronic arsenic poisoning associated with treatment of acute promyelocytic leukaemia
8. An analysis of time relations of electrocardiogram
9. Heavy metals and heavy-metal antagonists