-
1
-
-
40149092689
-
Pharmacological inhibition of DNA methylation induces proinvasive and prometastatic genes in vitro and in vivo
-
Ateeq B, Unterberger A, Szyf M and Rabbani SA (2008). Pharmacological inhibition of DNA methylation induces proinvasive and prometastatic genes in vitro and in vivo. Neoplasia 10: 266-278.
-
(2008)
Neoplasia
, vol.10
, pp. 266-278
-
-
Ateeq, B.1
Unterberger, A.2
Szyf, M.3
Rabbani, S.A.4
-
2
-
-
0034744639
-
Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer
-
Baylin SB, Esteller M, Rountree MR, Bachman KE, et al. (2001). Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer. Hum. Mol. Genet. 10: 687-692.
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 687-692
-
-
Baylin, S.B.1
Esteller, M.2
Rountree, M.R.3
Bachman, K.E.4
-
3
-
-
33745675111
-
Biology of colorectal liver metastases: A review
-
Bird NC, Mangnall D and Majeed AW (2006). Biology of colorectal liver metastases: A review. J. Surg. Oncol. 94: 68-80.
-
(2006)
J. Surg. Oncol.
, vol.94
, pp. 68-80
-
-
Bird, N.C.1
Mangnall, D.2
Majeed, A.W.3
-
4
-
-
0036216505
-
Epigenomics and epigenetic therapy of cancer
-
Brown R and Strathdee G (2002). Epigenomics and epigenetic therapy of cancer. Trends Mol. Med. 8: S43-S48.
-
(2002)
Trends Mol. Med.
, vol.8
-
-
Brown, R.1
Strathdee, G.2
-
5
-
-
0034648765
-
Angiogenesis in cancer and other diseases
-
Carmeliet P and Jain RK (2000). Angiogenesis in cancer and other diseases. Nature 407: 249-257.
-
(2000)
Nature
, vol.407
, pp. 249-257
-
-
Carmeliet, P.1
Jain, R.K.2
-
6
-
-
0029926820
-
S-Adenosylmethionine and methylation
-
Chiang PK, Gordon RK, Tal J, Zeng GC, et al. (1996). S-Adenosylmethionine and methylation. FASEB J. 10: 471-480.
-
(1996)
FASEB J.
, vol.10
, pp. 471-480
-
-
Chiang, P.K.1
Gordon, R.K.2
Tal, J.3
Zeng, G.C.4
-
7
-
-
0026573378
-
Inhibition of invasion and metastasis in cells transfected with an inhibitor of metalloproteinases
-
DeClerck YA, Perez N, Shimada H, Boone TC, et al. (1992). Inhibition of invasion and metastasis in cells transfected with an inhibitor of metalloproteinases. Cancer Res. 52: 701-708.
-
(1992)
Cancer Res.
, vol.52
, pp. 701-708
-
-
DeClerck, Y.A.1
Perez, N.2
Shimada, H.3
Boone, T.C.4
-
8
-
-
0038080948
-
The methyl donor S-Adenosylmethionine inhibits active demethylation of DNA: A candidate novel mechanism for the pharmacological effects of S-Adenosylmethionine
-
Detich N, Hamm S, Just G, Knox JD, et al. (2003). The methyl donor S-Adenosylmethionine inhibits active demethylation of DNA: a candidate novel mechanism for the pharmacological effects of S-Adenosylmethionine. J. Biol. Chem. 278: 20812-20820.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 20812-20820
-
-
Detich, N.1
Hamm, S.2
Just, G.3
Knox, J.D.4
-
9
-
-
0037068353
-
DNA methylation in cancer: Too much, but also too little
-
Ehrlich M (2002). DNA methylation in cancer: too much, but also too little. Oncogene 21: 5400-5413.
-
(2002)
Oncogene
, vol.21
, pp. 5400-5413
-
-
Ehrlich, M.1
-
10
-
-
13144251125
-
DNA methylation and cancer therapy: New developments and expectations
-
Esteller M (2005). DNA methylation and cancer therapy: new developments and expectations. Curr. Opin. Oncol. 17: 55-60.
-
(2005)
Curr. Opin. Oncol.
, vol.17
, pp. 55-60
-
-
Esteller, M.1
-
12
-
-
17444378859
-
Gene expression profiling of metastatic and nonmetastatic colorectal cancer cell lines
-
Futschik M, Jeffs A, Pattison S, Kasabov N, et al. (2002). Gene expression profiling of metastatic and nonmetastatic colorectal cancer cell lines. Genome Lett. 1: 26-34.
-
(2002)
Genome Lett.
, vol.1
, pp. 26-34
-
-
Futschik, M.1
Jeffs, A.2
Pattison, S.3
Kasabov, N.4
-
13
-
-
23044495284
-
Inactivation of the tissue inhibitor of metalloproteinases-2 gene by promoter hypermethylation in lymphoid malignancies
-
Galm O, Suzuki H, Akiyama Y, Esteller M, et al. (2005). Inactivation of the tissue inhibitor of metalloproteinases-2 gene by promoter hypermethylation in lymphoid malignancies. Oncogene 24: 4799-4805.
-
(2005)
Oncogene
, vol.24
, pp. 4799-4805
-
-
Galm, O.1
Suzuki, H.2
Akiyama, Y.3
Esteller, M.4
-
14
-
-
0032431941
-
Expression and role of matrix metalloproteinases MMP-2 and MMP-9 in human spinal column tumors
-
Gokaslan ZL, Chintala SK, York JE, Boyapati V, et al. (1998). Expression and role of matrix metalloproteinases MMP-2 and MMP-9 in human spinal column tumors. Clin. Exp. Metastasis 16: 721-728.
-
(1998)
Clin. Exp. Metastasis
, vol.16
, pp. 721-728
-
-
Gokaslan, Z.L.1
Chintala, S.K.2
York, J.E.3
Boyapati, V.4
-
15
-
-
0030717692
-
Tissue inhibitors of metalloproteinases: Structure, regulation and biological functions
-
Gomez DE, Alonso DF, Yoshiji H and Thorgeirsson UP (1997). Tissue inhibitors of metalloproteinases: structure, regulation and biological functions. Eur. J. Cell Biol. 74: 111-122.
-
(1997)
Eur. J. Cell Biol.
, vol.74
, pp. 111-122
-
-
Gomez, D.E.1
Alonso, D.F.2
Yoshiji, H.3
Thorgeirsson, U.P.4
-
16
-
-
0035870250
-
Down-regulation of vascular endothelial growth factor by tissue inhibitor of metalloproteinase-2: Effect on in vivo mammary tumor growth and angiogenesis
-
Hajitou A, Sounni NE, Devy L, Grignet-Debrus C, et al. (2001). Down-regulation of vascular endothelial growth factor by tissue inhibitor of metalloproteinase-2: effect on in vivo mammary tumor growth and angiogenesis. Cancer Res. 61: 3450-3457.
-
(2001)
Cancer Res.
, vol.61
, pp. 3450-3457
-
-
Hajitou, A.1
Sounni, N.E.2
Devy, L.3
Grignet-Debrus, C.4
-
17
-
-
0030012534
-
Overexpression of tissue inhibitor of metalloproteinases-2 retroviral-mediated gene transfer in vivo inhibits tumor growth and invasion
-
Imren S, Kohn DB, Shimada H, Blavier L, et al. (1996). Overexpression of tissue inhibitor of metalloproteinases-2 retroviral-mediated gene transfer in vivo inhibits tumor growth and invasion. Cancer Res. 56: 2891-2895.
-
(1996)
Cancer Res.
, vol.56
, pp. 2891-2895
-
-
Imren, S.1
Kohn, D.B.2
Shimada, H.3
Blavier, L.4
-
18
-
-
1642498263
-
Frequent hypermethylation of 5' flanking region of TIMP-2 gene in cervical cancer
-
Ivanova T, Vinokurova S, Petrenko A, Eshilev E, et al. (2004). Frequent hypermethylation of 5' flanking region of TIMP-2 gene in cervical cancer. Int. J. Cancer 108: 882-886.
-
(2004)
Int. J. Cancer
, vol.108
, pp. 882-886
-
-
Ivanova, T.1
Vinokurova, S.2
Petrenko, A.3
Eshilev, E.4
-
19
-
-
41349099104
-
Cancer statistics, 2008
-
Jemal A, Siegel R, Ward E, Hao Y, et al. (2008). Cancer statistics, 2008. CA Cancer J. Clin. 58: 71-96.
-
(2008)
CA Cancer J. Clin.
, vol.58
, pp. 71-96
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Hao, Y.4
-
20
-
-
43249095919
-
Tumor angiogenesis
-
Kerbel RS (2008). Tumor angiogenesis. N. Engl. J. Med. 358: 2039-2049.
-
(2008)
N. Engl. J. Med.
, vol.358
, pp. 2039-2049
-
-
Kerbel, R.S.1
-
21
-
-
0034469045
-
Transforming growth factor-beta and breast cancer: Transforming growth factor-beta/SMAD signaling defects and cancer
-
Kretzschmar M (2000). Transforming growth factor-beta and breast cancer: Transforming growth factor-beta/SMAD signaling defects and cancer. Breast Cancer Res. 2: 107-115.
-
(2000)
Breast Cancer Res.
, vol.2
, pp. 107-115
-
-
Kretzschmar, M.1
-
22
-
-
0019195010
-
Metastatic potential correlates with enzymatic degradation of basement membrane collagen
-
Liotta LA, Tryggvason K, Garbisa S, Hart I, et al. (1980). Metastatic potential correlates with enzymatic degradation of basement membrane collagen. Nature 284: 67-68.
-
(1980)
Nature
, vol.284
, pp. 67-68
-
-
Liotta, L.A.1
Tryggvason, K.2
Garbisa, S.3
Hart, I.4
-
23
-
-
0026027556
-
Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation
-
Liotta LA, Steeg PS and Stetler-Stevenson WG (1991). Cancer metastasis and angiogenesis: an imbalance of positive and negative regulation. Cell 64: 327-336.
-
(1991)
Cell
, vol.64
, pp. 327-336
-
-
Liotta, L.A.1
Steeg, P.S.2
Stetler-Stevenson, W.G.3
-
24
-
-
0002606253
-
The urokinase plasminogen activator system in cancer: Implications for tumor angiogenesis and metastasis
-
Mazar AP, Henkin J and Goldfarb RH (1999). The urokinase plasminogen activator system in cancer: implications for tumor angiogenesis and metastasis. Angiogenesis 3: 15-32.
-
(1999)
Angiogenesis
, vol.3
, pp. 15-32
-
-
Mazar, A.P.1
Henkin, J.2
Goldfarb, R.H.3
-
25
-
-
34250021354
-
Epidemiology of colorectal liver metastases
-
McMillan DC and McArdle CS (2007). Epidemiology of colorectal liver metastases. Surg. Oncol. 16: 3-5.
-
(2007)
Surg. Oncol.
, vol.16
, pp. 3-5
-
-
McMillan, D.C.1
McArdle, C.S.2
-
27
-
-
3843125363
-
Reversal of the hypomethylation status of urokinase (uPA) promoter blocks breast cancer growth and metastasis
-
Pakneshan P, Szyf M, Farias-Eisner R and Rabbani SA (2004). Reversal of the hypomethylation status of urokinase (uPA) promoter blocks breast cancer growth and metastasis. J. Biol. Chem. 279: 31735-31744.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 31735-31744
-
-
Pakneshan, P.1
Szyf, M.2
Farias-Eisner, R.3
Rabbani, S.A.4
-
29
-
-
34547728776
-
Epigenetic inactivation of the tissue inhibitor of metalloproteinase-2 (TIMP-2) gene in human prostate tumors
-
Pulukuri SM, Patibandla S, Patel J, Estes N, et al. (2007). Epigenetic inactivation of the tissue inhibitor of metalloproteinase-2 (TIMP-2) gene in human prostate tumors. Oncogene 26: 5229-5237.
-
(2007)
Oncogene
, vol.26
, pp. 5229-5237
-
-
Pulukuri, S.M.1
Patibandla, S.2
Patel, J.3
Estes, N.4
-
30
-
-
0041737535
-
Molecular mechanisms of glioma invasiveness: The role of proteases
-
Rao JS (2003). Molecular mechanisms of glioma invasiveness: the role of proteases. Nat. Rev. Cancer 3: 489-501.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 489-501
-
-
Rao, J.S.1
-
31
-
-
0019318994
-
DNA methylation and gene function
-
Razin A and Riggs AD (1980). DNA methylation and gene function. Science 210: 604-610.
-
(1980)
Science
, vol.210
, pp. 604-610
-
-
Razin, A.1
Riggs, A.D.2
-
32
-
-
21344459502
-
Treatment of liver metastases of colorectal cancer
-
Rothbarth J and van de Velde CJ (2005). Treatment of liver metastases of colorectal cancer. Ann. Oncol. 16: 144-149.
-
(2005)
Ann. Oncol.
, vol.16
, pp. 144-149
-
-
Rothbarth, J.1
van de Velde, C.J.2
-
33
-
-
33749483782
-
Alteration of the methylation status of tumor-promoting genes decreases prostate cancer cell invasiveness and tumorigenesis in vitro and in vivo
-
Shukeir N, Pakneshan P, Chen G, Szyf M, et al. (2006). Alteration of the methylation status of tumor-promoting genes decreases prostate cancer cell invasiveness and tumorigenesis in vitro and in vivo. Cancer Res. 66: 9202-9210.
-
(2006)
Cancer Res.
, vol.66
, pp. 9202-9210
-
-
Shukeir, N.1
Pakneshan, P.2
Chen, G.3
Szyf, M.4
-
34
-
-
0027333411
-
Tumor cell interactions with the extracellular matrix during invasion and metastasis
-
Stetler-Stevenson WG, Aznavoorian S and Liotta LA (1993). Tumor cell interactions with the extracellular matrix during invasion and metastasis. Annu. Rev. Cell Biol. 9: 541-573.
-
(1993)
Annu. Rev. Cell Biol.
, vol.9
, pp. 541-573
-
-
Stetler-Stevenson, W.G.1
Aznavoorian, S.2
Liotta, L.A.3
-
35
-
-
0036613250
-
A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer
-
Suzuki H, Gabrielson E, Chen W, Anbazhagan R, et al. (2002). A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer. Nat. Genet. 31: 141-149.
-
(2002)
Nat. Genet.
, vol.31
, pp. 141-149
-
-
Suzuki, H.1
Gabrielson, E.2
Chen, W.3
Anbazhagan, R.4
-
36
-
-
0032545643
-
TIMP-2 over-expression reduces invasion and angiogenesis and protects B16F10 melanoma cells from apoptosis
-
Valente P, Fassina G, Melchiori A, Masiello L, et al. (1998). TIMP-2 over-expression reduces invasion and angiogenesis and protects B16F10 melanoma cells from apoptosis. Int. J. Cancer 75: 246-253.
-
(1998)
Int. J. Cancer
, vol.75
, pp. 246-253
-
-
Valente, P.1
Fassina, G.2
Melchiori, A.3
Masiello, L.4
-
37
-
-
9044246674
-
Differential expression of membrane-type matrix metalloproteinase and its correlation with gelatinase A activation in human malignant brain tumors in vivo and in vitro
-
Yamamoto M, Mohanam S, Sawaya R, Fuller GN, et al. (1996). Differential expression of membrane-type matrix metalloproteinase and its correlation with gelatinase A activation in human malignant brain tumors in vivo and in vitro. Cancer Res. 56: 384-392.
-
(1996)
Cancer Res.
, vol.56
, pp. 384-392
-
-
Yamamoto, M.1
Mohanam, S.2
Sawaya, R.3
Fuller, G.N.4
-
38
-
-
84860266396
-
DNA methylation biomarker candidates for early detection of colon cancer
-
Yi JM, Dhir M, Guzzetta AA, Iacobuzio-Donahue CA, et al. (2012). DNA methylation biomarker candidates for early detection of colon cancer. Tumour. Biol. 33: 363-372.
-
(2012)
Tumour. Biol.
, vol.33
, pp. 363-372
-
-
Yi, J.M.1
Dhir, M.2
Guzzetta, A.A.3
Iacobuzio-Donahue, C.A.4
-
39
-
-
0032918414
-
TGF-beta signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development
-
Yin JJ, Selander K, Chirgwin JM, Dallas M, et al. (1999). TGF-beta signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development. J. Clin. Invest. 103: 197-206.
-
(1999)
J. Clin. Invest.
, vol.103
, pp. 197-206
-
-
Yin, J.J.1
Selander, K.2
Chirgwin, J.M.3
Dallas, M.4
-
40
-
-
0035827535
-
Inhibitory effect of selenite on invasion of HT1080 tumor cells
-
Yoon SO, Kim MM and Chung AS (2001). Inhibitory effect of selenite on invasion of HT1080 tumor cells. J. Biol. Chem. 276: 20085-20092.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 20085-20092
-
-
Yoon, S.O.1
Kim, M.M.2
Chung, A.S.3
|