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Volumn 8, Issue 4, 2013, Pages

The BDNF Val66Met Polymorphism Has Opposite Effects on Memory Circuits of Multiple Sclerosis Patients and Controls

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; METHIONINE; VALINE; BRAIN DERIVED NEUROTROPHIC FACTOR, HUMAN; BRAIN-DERIVED NEUROTROPHIC FACTOR, HUMAN; PRIMER DNA;

EID: 84876152308     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0061063     Document Type: Article
Times cited : (20)

References (75)
  • 1
    • 0036214823 scopus 로고    scopus 로고
    • Memory in multiple sclerosis: contextual encoding deficits
    • Thornton AE, Raz N, Tucke KA, (2002) Memory in multiple sclerosis: contextual encoding deficits. J Int Neuropsychol Soc 8: 395-409.
    • (2002) J Int Neuropsychol Soc , vol.8 , pp. 395-409
    • Thornton, A.E.1    Raz, N.2    Tucke, K.A.3
  • 2
    • 79958223011 scopus 로고    scopus 로고
    • Risk factors for and management of cognitive dysfunction in multiple sclerosis
    • Benedict RH, Zivadinov R, (2011) Risk factors for and management of cognitive dysfunction in multiple sclerosis. Nat Rev Neurol 7: 332-342.
    • (2011) Nat Rev Neurol , vol.7 , pp. 332-342
    • Benedict, R.H.1    Zivadinov, R.2
  • 3
    • 0042671368 scopus 로고    scopus 로고
    • Statistical mapping analysis of lesion location and neurological disability in multiple sclerosis: application to 452 patient data sets
    • Charil A, Zijdenbos AP, Taylor J, Boelman C, Worsley KJ, et al. (2003) Statistical mapping analysis of lesion location and neurological disability in multiple sclerosis: application to 452 patient data sets. Neuroimage 19: 532-544.
    • (2003) Neuroimage , vol.19 , pp. 532-544
    • Charil, A.1    Zijdenbos, A.P.2    Taylor, J.3    Boelman, C.4    Worsley, K.J.5
  • 4
    • 0041660848 scopus 로고    scopus 로고
    • Risk for relatives of patients with multiple sclerosis in central Sardinia, Italy
    • Prokopenko I, Montomoli C, Ferrai R, Musu L, Piras ML, et al. (2003) Risk for relatives of patients with multiple sclerosis in central Sardinia, Italy. Neuroepidemiology 22: 290-296.
    • (2003) Neuroepidemiology , vol.22 , pp. 290-296
    • Prokopenko, I.1    Montomoli, C.2    Ferrai, R.3    Musu, L.4    Piras, M.L.5
  • 5
    • 0038480612 scopus 로고    scopus 로고
    • Longitudinal study of cognitive dysfunction in multiple sclerosis: neuropsychological, neuroradiological, and neurophysiological findings
    • Piras MR, Magnano I, Canu ED, Paulus KS, Satta WM, et al. (2003) Longitudinal study of cognitive dysfunction in multiple sclerosis: neuropsychological, neuroradiological, and neurophysiological findings. J Neurol Neurosurg Psychiatry 74: 878-885.
    • (2003) J Neurol Neurosurg Psychiatry , vol.74 , pp. 878-885
    • Piras, M.R.1    Magnano, I.2    Canu, E.D.3    Paulus, K.S.4    Satta, W.M.5
  • 6
    • 0036260275 scopus 로고    scopus 로고
    • Cognitive function and fMRI in patients with multiple sclerosis: evidence for compensatory cortical activation during an attention task
    • Staffen W, Mair A, Zauner H, Unterrainer J, Niederhofer H, et al. (2002) Cognitive function and fMRI in patients with multiple sclerosis: evidence for compensatory cortical activation during an attention task. Brain 125: 1275-1282.
    • (2002) Brain , vol.125 , pp. 1275-1282
    • Staffen, W.1    Mair, A.2    Zauner, H.3    Unterrainer, J.4    Niederhofer, H.5
  • 7
    • 75649136616 scopus 로고    scopus 로고
    • Preserved brain adaptive properties in patients with benign multiple sclerosis
    • Rocca MA, Ceccarelli A, Rodegher M, Misci P, Riccitelli G, et al. (2010) Preserved brain adaptive properties in patients with benign multiple sclerosis. Neurology 74: 142-149.
    • (2010) Neurology , vol.74 , pp. 142-149
    • Rocca, M.A.1    Ceccarelli, A.2    Rodegher, M.3    Misci, P.4    Riccitelli, G.5
  • 8
    • 60149084840 scopus 로고    scopus 로고
    • Short-term adaptation to a simple motor task: a physiological process preserved in multiple sclerosis
    • Mancini L, Ciccarelli O, Manfredonia F, Thornton JS, Agosta F, et al. (2009) Short-term adaptation to a simple motor task: a physiological process preserved in multiple sclerosis. Neuroimage 45: 500-511.
    • (2009) Neuroimage , vol.45 , pp. 500-511
    • Mancini, L.1    Ciccarelli, O.2    Manfredonia, F.3    Thornton, J.S.4    Agosta, F.5
  • 9
    • 69249108133 scopus 로고    scopus 로고
    • Is a preserved functional reserve a mechanism limiting clinical impairment in pediatric MS patients?
    • Rocca MA, Absinta M, Ghezzi A, Moiola L, Comi G, et al. (2009) Is a preserved functional reserve a mechanism limiting clinical impairment in pediatric MS patients? Hum Brain Mapp 30: 2844-2851.
    • (2009) Hum Brain Mapp , vol.30 , pp. 2844-2851
    • Rocca, M.A.1    Absinta, M.2    Ghezzi, A.3    Moiola, L.4    Comi, G.5
  • 10
  • 11
    • 24944571009 scopus 로고    scopus 로고
    • Cortical adaptation in patients with MS: a cross-sectional functional MRI study of disease phenotypes
    • Rocca MA, Colombo B, Falini A, Ghezzi A, Martinelli V, et al. (2005) Cortical adaptation in patients with MS: a cross-sectional functional MRI study of disease phenotypes. Lancet Neurol 4: 618-626.
    • (2005) Lancet Neurol , vol.4 , pp. 618-626
    • Rocca, M.A.1    Colombo, B.2    Falini, A.3    Ghezzi, A.4    Martinelli, V.5
  • 12
    • 0036192631 scopus 로고    scopus 로고
    • Adaptive functional changes in the cerebral cortex of patients with nondisabling multiple sclerosis correlate with the extent of brain structural damage
    • Rocca MA, Falini A, Colombo B, Scotti G, Comi G, et al. (2002) Adaptive functional changes in the cerebral cortex of patients with nondisabling multiple sclerosis correlate with the extent of brain structural damage. Ann Neurol 51: 330-339.
    • (2002) Ann Neurol , vol.51 , pp. 330-339
    • Rocca, M.A.1    Falini, A.2    Colombo, B.3    Scotti, G.4    Comi, G.5
  • 14
    • 84855422549 scopus 로고    scopus 로고
    • Fornix damage limits verbal memory functional compensation in multiple sclerosis
    • Kern KC, Ekstrom AD, Suthana NA, Giesser BS, Montag M, et al. (2012) Fornix damage limits verbal memory functional compensation in multiple sclerosis. Neuroimage 59: 2932-2940.
    • (2012) Neuroimage , vol.59 , pp. 2932-2940
    • Kern, K.C.1    Ekstrom, A.D.2    Suthana, N.A.3    Giesser, B.S.4    Montag, M.5
  • 15
    • 43949138935 scopus 로고    scopus 로고
    • Identification of neurogenetic pathways of risk for psychopathology
    • Fisher PM, Munoz KE, Hariri AR, (2008) Identification of neurogenetic pathways of risk for psychopathology. Am J Med Genet C Semin Med Genet 148C: 147-153.
    • (2008) Am J Med Genet C Semin Med Genet , vol.148 C , pp. 147-153
    • Fisher, P.M.1    Munoz, K.E.2    Hariri, A.R.3
  • 16
    • 35649022177 scopus 로고    scopus 로고
    • Neuroimaging: technologies at the interface of genes, brain, and behavior
    • Bigos KL, Hariri AR, (2007) Neuroimaging: technologies at the interface of genes, brain, and behavior. Neuroimaging Clin N Am 17: 459-467, viii.
    • (2007) Neuroimaging Clin N Am , vol.17
    • Bigos, K.L.1    Hariri, A.R.2
  • 17
    • 33749020312 scopus 로고    scopus 로고
    • Developmental imaging genetics: challenges and promises for translational research
    • Viding E, Williamson DE, Hariri AR, (2006) Developmental imaging genetics: challenges and promises for translational research. Dev Psychopathol 18: 877-892.
    • (2006) Dev Psychopathol , vol.18 , pp. 877-892
    • Viding, E.1    Williamson, D.E.2    Hariri, A.R.3
  • 18
    • 33747249445 scopus 로고    scopus 로고
    • Neuroimaging studies of serotonin gene polymorphisms: exploring the interplay of genes, brain, and behavior
    • Brown SM, Hariri AR, (2006) Neuroimaging studies of serotonin gene polymorphisms: exploring the interplay of genes, brain, and behavior. Cogn Affect Behav Neurosci 6: 44-52.
    • (2006) Cogn Affect Behav Neurosci , vol.6 , pp. 44-52
    • Brown, S.M.1    Hariri, A.R.2
  • 19
    • 33646482854 scopus 로고    scopus 로고
    • Imaging genetics: perspectives from studies of genetically driven variation in serotonin function and corticolimbic affective processing
    • Hariri AR, Drabant EM, Weinberger DR, (2006) Imaging genetics: perspectives from studies of genetically driven variation in serotonin function and corticolimbic affective processing. Biol Psychiatry 59: 888-897.
    • (2006) Biol Psychiatry , vol.59 , pp. 888-897
    • Hariri, A.R.1    Drabant, E.M.2    Weinberger, D.R.3
  • 20
    • 0037462449 scopus 로고    scopus 로고
    • The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function
    • Egan MF, Kojima M, Callicott JH, Goldberg TE, Kolachana BS, et al. (2003) The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell 112: 257-269.
    • (2003) Cell , vol.112 , pp. 257-269
    • Egan, M.F.1    Kojima, M.2    Callicott, J.H.3    Goldberg, T.E.4    Kolachana, B.S.5
  • 21
    • 70350446962 scopus 로고    scopus 로고
    • New insights in the biology of BDNF synthesis and release: implications in CNS function
    • Greenberg ME, Xu B, Lu B, Hempstead BL, (2009) New insights in the biology of BDNF synthesis and release: implications in CNS function. J Neurosci 29: 12764-12767.
    • (2009) J Neurosci , vol.29 , pp. 12764-12767
    • Greenberg, M.E.1    Xu, B.2    Lu, B.3    Hempstead, B.L.4
  • 22
    • 0043135252 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor val66met polymorphism affects human memory-related hippocampal activity and predicts memory performance
    • Hariri AR, Goldberg TE, Mattay VS, Kolachana BS, Callicott JH, et al. (2003) Brain-derived neurotrophic factor val66met polymorphism affects human memory-related hippocampal activity and predicts memory performance. J Neurosci 23: 6690-6694.
    • (2003) J Neurosci , vol.23 , pp. 6690-6694
    • Hariri, A.R.1    Goldberg, T.E.2    Mattay, V.S.3    Kolachana, B.S.4    Callicott, J.H.5
  • 23
    • 0037359267 scopus 로고    scopus 로고
    • BDNF and activity-dependent synaptic modulation
    • Lu B, (2003) BDNF and activity-dependent synaptic modulation. Learn Mem 10: 86-98.
    • (2003) Learn Mem , vol.10 , pp. 86-98
    • Lu, B.1
  • 24
    • 77954421126 scopus 로고    scopus 로고
    • The BDNF Val66Met polymorphism impairs NMDA receptor-dependent synaptic plasticity in the hippocampus
    • Ninan I, Bath KG, Dagar K, Perez-Castro R, Plummer MR, et al. (2010) The BDNF Val66Met polymorphism impairs NMDA receptor-dependent synaptic plasticity in the hippocampus. J Neurosci 30: 8866-8870.
    • (2010) J Neurosci , vol.30 , pp. 8866-8870
    • Ninan, I.1    Bath, K.G.2    Dagar, K.3    Perez-Castro, R.4    Plummer, M.R.5
  • 25
    • 77957293766 scopus 로고    scopus 로고
    • Involvement of brain-derived neurotrophic factor (BDNF) in MP4-induced autoimmune encephalomyelitis
    • Javeri S, Rodi M, Tary-Lehmann M, Lehmann PV, Addicks K, et al. (2010) Involvement of brain-derived neurotrophic factor (BDNF) in MP4-induced autoimmune encephalomyelitis. Clin Immunol 137: 181-189.
    • (2010) Clin Immunol , vol.137 , pp. 181-189
    • Javeri, S.1    Rodi, M.2    Tary-Lehmann, M.3    Lehmann, P.V.4    Addicks, K.5
  • 26
    • 84857030341 scopus 로고    scopus 로고
    • Central nervous system rather than immune cell-derived BDNF mediates axonal protective effects early in autoimmune demyelination
    • Lee DH, Geyer E, Flach AC, Jung K, Gold R, et al. (2012) Central nervous system rather than immune cell-derived BDNF mediates axonal protective effects early in autoimmune demyelination. Acta Neuropathol 123: 247-258.
    • (2012) Acta Neuropathol , vol.123 , pp. 247-258
    • Lee, D.H.1    Geyer, E.2    Flach, A.C.3    Jung, K.4    Gold, R.5
  • 27
    • 33847282422 scopus 로고    scopus 로고
    • Investigating the role of brain-derived neurotrophic factor in relapsing-remitting multiple sclerosis
    • Liguori M, Fera F, Gioia MC, Valentino P, Manna I, et al. (2007) Investigating the role of brain-derived neurotrophic factor in relapsing-remitting multiple sclerosis. Genes Brain Behav 6: 177-183.
    • (2007) Genes Brain Behav , vol.6 , pp. 177-183
    • Liguori, M.1    Fera, F.2    Gioia, M.C.3    Valentino, P.4    Manna, I.5
  • 28
    • 77950128963 scopus 로고    scopus 로고
    • Correlations between peripheral blood mononuclear cell production of BDNF, TNF-alpha, IL-6, IL-10 and cognitive performances in multiple sclerosis patients
    • Patanella AK, Zinno M, Quaranta D, Nociti V, Frisullo G, et al. (2010) Correlations between peripheral blood mononuclear cell production of BDNF, TNF-alpha, IL-6, IL-10 and cognitive performances in multiple sclerosis patients. J Neurosci Res 88: 1106-1112.
    • (2010) J Neurosci Res , vol.88 , pp. 1106-1112
    • Patanella, A.K.1    Zinno, M.2    Quaranta, D.3    Nociti, V.4    Frisullo, G.5
  • 29
    • 79551599360 scopus 로고    scopus 로고
    • BDNF Val66Met polymorphism and brain volumes in multiple sclerosis
    • Dinacci D, Tessitore A, Russo A, De Bonis ML, Lavorgna L, et al. (2011) BDNF Val66Met polymorphism and brain volumes in multiple sclerosis. Neurol Sci 32: 117-123.
    • (2011) Neurol Sci , vol.32 , pp. 117-123
    • Dinacci, D.1    Tessitore, A.2    Russo, A.3    De Bonis, M.L.4    Lavorgna, L.5
  • 30
    • 78650530895 scopus 로고    scopus 로고
    • Effect of Met66 allele of the BDNF rs6265 SNP on regional gray matter volumes in patients with multiple sclerosis: A voxel-based morphometry study
    • Ramasamy DP, Ramanathan M, Cox JL, Antulov R, Weinstock-Guttman B, et al. (2011) Effect of Met66 allele of the BDNF rs6265 SNP on regional gray matter volumes in patients with multiple sclerosis: A voxel-based morphometry study. Pathophysiology 18: 53-60.
    • (2011) Pathophysiology , vol.18 , pp. 53-60
    • Ramasamy, D.P.1    Ramanathan, M.2    Cox, J.L.3    Antulov, R.4    Weinstock-Guttman, B.5
  • 31
    • 35548947568 scopus 로고    scopus 로고
    • Preservation of gray matter volume in multiple sclerosis patients with the Met allele of the rs6265 (Val66Met) SNP of brain-derived neurotrophic factor
    • Zivadinov R, Weinstock-Guttman B, Benedict R, Tamano-Blanco M, Hussein S, et al. (2007) Preservation of gray matter volume in multiple sclerosis patients with the Met allele of the rs6265 (Val66Met) SNP of brain-derived neurotrophic factor. Hum Mol Genet 16: 2659-2668.
    • (2007) Hum Mol Genet , vol.16 , pp. 2659-2668
    • Zivadinov, R.1    Weinstock-Guttman, B.2    Benedict, R.3    Tamano-Blanco, M.4    Hussein, S.5
  • 32
    • 80051928161 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor val66met polymorphism and hippocampal activation during episodic encoding and retrieval tasks
    • Dennis NA, Cabeza R, Need AC, Waters-Metenier S, Goldstein DB, et al. (2011) Brain-derived neurotrophic factor val66met polymorphism and hippocampal activation during episodic encoding and retrieval tasks. Hippocampus 21: 980-989.
    • (2011) Hippocampus , vol.21 , pp. 980-989
    • Dennis, N.A.1    Cabeza, R.2    Need, A.C.3    Waters-Metenier, S.4    Goldstein, D.B.5
  • 33
    • 84856255919 scopus 로고    scopus 로고
    • Hippocampal volume and the brain-derived neurotrophic factor Val66Met polymorphism in first episode psychosis
    • Smith GN, Thornton AE, Lang DJ, Macewan GW, Ehmann TS, et al. (2012) Hippocampal volume and the brain-derived neurotrophic factor Val66Met polymorphism in first episode psychosis. Schizophr Res 134: 253-259.
    • (2012) Schizophr Res , vol.134 , pp. 253-259
    • Smith, G.N.1    Thornton, A.E.2    Lang, D.J.3    Macewan, G.W.4    Ehmann, T.S.5
  • 34
    • 33646097451 scopus 로고    scopus 로고
    • BDNF Val66Met allele is associated with reduced hippocampal volume in healthy subjects
    • Bueller JA, Aftab M, Sen S, Gomez-Hassan D, Burmeister M, et al. (2006) BDNF Val66Met allele is associated with reduced hippocampal volume in healthy subjects. Biol Psychiatry 59: 812-815.
    • (2006) Biol Psychiatry , vol.59 , pp. 812-815
    • Bueller, J.A.1    Aftab, M.2    Sen, S.3    Gomez-Hassan, D.4    Burmeister, M.5
  • 35
    • 8544249878 scopus 로고    scopus 로고
    • The brain-derived neurotrophic factor val66met polymorphism and variation in human cortical morphology
    • Pezawas L, Verchinski BA, Mattay VS, Callicott JH, Kolachana BS, et al. (2004) The brain-derived neurotrophic factor val66met polymorphism and variation in human cortical morphology. J Neurosci 24: 10099-10102.
    • (2004) J Neurosci , vol.24 , pp. 10099-10102
    • Pezawas, L.1    Verchinski, B.A.2    Mattay, V.S.3    Callicott, J.H.4    Kolachana, B.S.5
  • 36
    • 84861459607 scopus 로고    scopus 로고
    • BDNF Val66Met genotype modulates the effect of childhood adversity on subgenual anterior cingulate cortex volume in healthy subjects
    • Gerritsen L, Tendolkar I, Franke B, Vasquez AA, Kooijman S, et al. (2012) BDNF Val66Met genotype modulates the effect of childhood adversity on subgenual anterior cingulate cortex volume in healthy subjects. Mol Psychiatry 17: 597-603.
    • (2012) Mol Psychiatry , vol.17 , pp. 597-603
    • Gerritsen, L.1    Tendolkar, I.2    Franke, B.3    Vasquez, A.A.4    Kooijman, S.5
  • 37
    • 63849327805 scopus 로고    scopus 로고
    • Brain derived neurotrophic factor Val66Met polymorphism, the five factor model of personality and hippocampal volume: Implications for depressive illness
    • Joffe RT, Gatt JM, Kemp AH, Grieve S, Dobson-Stone C, et al. (2009) Brain derived neurotrophic factor Val66Met polymorphism, the five factor model of personality and hippocampal volume: Implications for depressive illness. Hum Brain Mapp 30: 1246-1256.
    • (2009) Hum Brain Mapp , vol.30 , pp. 1246-1256
    • Joffe, R.T.1    Gatt, J.M.2    Kemp, A.H.3    Grieve, S.4    Dobson-Stone, C.5
  • 38
    • 84860351742 scopus 로고    scopus 로고
    • Identification of common variants associated with human hippocampal and intracranial volumes
    • Stein JL, Medland SE, Vasquez AA, Hibar DP, Senstad RE, et al. (2012) Identification of common variants associated with human hippocampal and intracranial volumes. Nat Genet 44: 552-561.
    • (2012) Nat Genet , vol.44 , pp. 552-561
    • Stein, J.L.1    Medland, S.E.2    Vasquez, A.A.3    Hibar, D.P.4    Senstad, R.E.5
  • 39
    • 74449090368 scopus 로고    scopus 로고
    • The effects of BDNF Val66Met polymorphism on brain function in controls and patients with multiple sclerosis: an imaging genetic study
    • Cerasa A, Tongiorgi E, Fera F, Gioia MC, Valentino P, et al. (2010) The effects of BDNF Val66Met polymorphism on brain function in controls and patients with multiple sclerosis: an imaging genetic study. Behav Brain Res 207: 377-386.
    • (2010) Behav Brain Res , vol.207 , pp. 377-386
    • Cerasa, A.1    Tongiorgi, E.2    Fera, F.3    Gioia, M.C.4    Valentino, P.5
  • 40
    • 0032499196 scopus 로고    scopus 로고
    • A cortical representation of the local visual environment
    • Epstein R, Kanwisher N, (1998) A cortical representation of the local visual environment. Nature 392: 598-601.
    • (1998) Nature , vol.392 , pp. 598-601
    • Epstein, R.1    Kanwisher, N.2
  • 41
    • 0036948607 scopus 로고    scopus 로고
    • Differential contributions of the parahippocampal place area and the anterior hippocampus to human memory for scenes
    • Kohler S, Crane J, Milner B, (2002) Differential contributions of the parahippocampal place area and the anterior hippocampus to human memory for scenes. Hippocampus 12: 718-723.
    • (2002) Hippocampus , vol.12 , pp. 718-723
    • Kohler, S.1    Crane, J.2    Milner, B.3
  • 42
    • 67349269547 scopus 로고    scopus 로고
    • Encoding and retrieving faces and places: distinguishing process- and stimulus-specific differences in brain activity
    • Prince SE, Dennis NA, Cabeza R, (2009) Encoding and retrieving faces and places: distinguishing process- and stimulus-specific differences in brain activity. Neuropsychologia 47: 2282-2289.
    • (2009) Neuropsychologia , vol.47 , pp. 2282-2289
    • Prince, S.E.1    Dennis, N.A.2    Cabeza, R.3
  • 43
    • 79953019448 scopus 로고    scopus 로고
    • Episodic memory retrieval, parietal cortex, and the default mode network: functional and topographic analyses
    • Sestieri C, Corbetta M, Romani GL, Shulman GL, (2011) Episodic memory retrieval, parietal cortex, and the default mode network: functional and topographic analyses. J Neurosci 31: 4407-4420.
    • (2011) J Neurosci , vol.31 , pp. 4407-4420
    • Sestieri, C.1    Corbetta, M.2    Romani, G.L.3    Shulman, G.L.4
  • 44
    • 79952501096 scopus 로고    scopus 로고
    • Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria
    • Polman CH, Reingold SC, Banwell B, Clanet M, Cohen JA, et al. (2011) Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria. Ann Neurol 69: 292-302.
    • (2011) Ann Neurol , vol.69 , pp. 292-302
    • Polman, C.H.1    Reingold, S.C.2    Banwell, B.3    Clanet, M.4    Cohen, J.A.5
  • 45
    • 59849118012 scopus 로고    scopus 로고
    • A longitudinal observation of brain-derived neurotrophic factor mRNA levels in patients with relapsing-remitting multiple sclerosis
    • Liguori M, Fera F, Patitucci A, Manna I, Condino F, et al. (2009) A longitudinal observation of brain-derived neurotrophic factor mRNA levels in patients with relapsing-remitting multiple sclerosis. Brain Res 1256: 123-128.
    • (2009) Brain Res , vol.1256 , pp. 123-128
    • Liguori, M.1    Fera, F.2    Patitucci, A.3    Manna, I.4    Condino, F.5
  • 47
    • 0021035886 scopus 로고
    • Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS)
    • Kurtzke JF, (1983) Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology 33: 1444-1452.
    • (1983) Neurology , vol.33 , pp. 1444-1452
    • Kurtzke, J.F.1
  • 48
    • 0015021890 scopus 로고
    • The assessment and analysis of handedness: the Edinburgh inventory
    • Oldfield RC, (1971) The assessment and analysis of handedness: the Edinburgh inventory. Neuropsychologia 9: 97-113.
    • (1971) Neuropsychologia , vol.9 , pp. 97-113
    • Oldfield, R.C.1
  • 50
    • 0017033821 scopus 로고
    • A modified card sorting test sensitive to frontal lobe defects
    • Nelson HE, (1976) A modified card sorting test sensitive to frontal lobe defects. Cortex 12: 313-324.
    • (1976) Cortex , vol.12 , pp. 313-324
    • Nelson, H.E.1
  • 55
    • 0034798404 scopus 로고    scopus 로고
    • Cognitive dysfunction in early-onset multiple sclerosis: a reappraisal after 10 years
    • Amato MP, Ponziani G, Siracusa G, Sorbi S, (2001) Cognitive dysfunction in early-onset multiple sclerosis: a reappraisal after 10 years. Arch Neurol 58: 1602-1606.
    • (2001) Arch Neurol , vol.58 , pp. 1602-1606
    • Amato, M.P.1    Ponziani, G.2    Siracusa, G.3    Sorbi, S.4
  • 56
    • 33646588352 scopus 로고    scopus 로고
    • Adaptive cortical changes and the functional correlates of visuo-motor integration in relapsing-remitting multiple sclerosis
    • Cerasa A, Fera F, Gioia MC, Liguori M, Passamonti L, et al. (2006) Adaptive cortical changes and the functional correlates of visuo-motor integration in relapsing-remitting multiple sclerosis. Brain Res Bull 69: 597-605.
    • (2006) Brain Res Bull , vol.69 , pp. 597-605
    • Cerasa, A.1    Fera, F.2    Gioia, M.C.3    Liguori, M.4    Passamonti, L.5
  • 57
    • 34548120898 scopus 로고    scopus 로고
    • Impact of individual cognitive profile on visuo-motor reorganization in relapsing-remitting multiple sclerosis
    • Gioia MC, Cerasa A, Liguori M, Passamonti L, Condino F, et al. (2007) Impact of individual cognitive profile on visuo-motor reorganization in relapsing-remitting multiple sclerosis. Brain Res 1167: 71-79.
    • (2007) Brain Res , vol.1167 , pp. 71-79
    • Gioia, M.C.1    Cerasa, A.2    Liguori, M.3    Passamonti, L.4    Condino, F.5
  • 58
    • 70350325178 scopus 로고    scopus 로고
    • Neurofunctional correlates of personality traits in relapsing-remitting multiple sclerosis: an fMRI study
    • Gioia MC, Cerasa A, Valentino P, Fera F, Nistico R, et al. (2009) Neurofunctional correlates of personality traits in relapsing-remitting multiple sclerosis: an fMRI study. Brain Cogn 71: 320-327.
    • (2009) Brain Cogn , vol.71 , pp. 320-327
    • Gioia, M.C.1    Cerasa, A.2    Valentino, P.3    Fera, F.4    Nistico, R.5
  • 59
    • 72649083520 scopus 로고    scopus 로고
    • Neurobiological mechanisms underlying emotional processing in relapsing-remitting multiple sclerosis
    • Passamonti L, Cerasa A, Liguori M, Gioia MC, Valentino P, et al. (2009) Neurobiological mechanisms underlying emotional processing in relapsing-remitting multiple sclerosis. Brain 132: 3380-3391.
    • (2009) Brain , vol.132 , pp. 3380-3391
    • Passamonti, L.1    Cerasa, A.2    Liguori, M.3    Gioia, M.C.4    Valentino, P.5
  • 60
    • 51549099524 scopus 로고
    • The assessment of anxiety states by rating
    • Hamilton M, (1959) The assessment of anxiety states by rating. Br J Med Psychol 32: 50-55.
    • (1959) Br J Med Psychol , vol.32 , pp. 50-55
    • Hamilton, M.1
  • 61
    • 10744220806 scopus 로고    scopus 로고
    • Italian version of the Chicago multiscale depression inventory: translation, adaptation and testing in people with multiple sclerosis
    • Solari A, Motta A, Mendozzi L, Aridon P, Bergamaschi R, et al. (2004) Italian version of the Chicago multiscale depression inventory: translation, adaptation and testing in people with multiple sclerosis. Neurol Sci 24: 375-383.
    • (2004) Neurol Sci , vol.24 , pp. 375-383
    • Solari, A.1    Motta, A.2    Mendozzi, L.3    Aridon, P.4    Bergamaschi, R.5
  • 62
    • 0035940420 scopus 로고    scopus 로고
    • When zero is not zero: the problem of ambiguous baseline conditions in fMRI
    • Stark CE, Squire LR, (2001) When zero is not zero: the problem of ambiguous baseline conditions in fMRI. Proc Natl Acad Sci U S A 98: 12760-12766.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 12760-12766
    • Stark, C.E.1    Squire, L.R.2
  • 63
    • 0033201364 scopus 로고    scopus 로고
    • Automatic 3-D segmentation of internal structures of the head in MR images using a combination of similarity and free-form transformations: Part I, Methodology and validation on normal subjects
    • Dawant BM, Hartmann SL, Thirion JP, Maes F, Vandermeulen D, et al. (1999) Automatic 3-D segmentation of internal structures of the head in MR images using a combination of similarity and free-form transformations: Part I, Methodology and validation on normal subjects. IEEE Trans Med Imaging 18: 909-916.
    • (1999) IEEE Trans Med Imaging , vol.18 , pp. 909-916
    • Dawant, B.M.1    Hartmann, S.L.2    Thirion, J.P.3    Maes, F.4    Vandermeulen, D.5
  • 64
    • 0036742197 scopus 로고    scopus 로고
    • Accurate, robust, and automated longitudinal and cross-sectional brain change analysis
    • Smith SM, Zhang Y, Jenkinson M, Chen J, Matthews PM, et al. (2002) Accurate, robust, and automated longitudinal and cross-sectional brain change analysis. Neuroimage 17: 479-489.
    • (2002) Neuroimage , vol.17 , pp. 479-489
    • Smith, S.M.1    Zhang, Y.2    Jenkinson, M.3    Chen, J.4    Matthews, P.M.5
  • 65
    • 2342527831 scopus 로고    scopus 로고
    • Influence of apolipoprotein E epsilon4 genotype on brain tissue integrity in relapsing-remitting multiple sclerosis
    • De Stefano N, Bartolozzi ML, Nacmias B, Zipoli V, Mortilla M, et al. (2004) Influence of apolipoprotein E epsilon4 genotype on brain tissue integrity in relapsing-remitting multiple sclerosis. Arch Neurol 61: 536-540.
    • (2004) Arch Neurol , vol.61 , pp. 536-540
    • De Stefano, N.1    Bartolozzi, M.L.2    Nacmias, B.3    Zipoli, V.4    Mortilla, M.5
  • 66
    • 84895064829 scopus 로고    scopus 로고
    • MR imaging and cognitive correlates of relapsing-remitting multiple sclerosis patients with cerebellar symptoms
    • Cerasa A, Valentino P, Chiriaco C, Pirritano D, Nistico R, et al. (2012) MR imaging and cognitive correlates of relapsing-remitting multiple sclerosis patients with cerebellar symptoms. J Neurol.
    • (2012) J Neurol
    • Cerasa, A.1    Valentino, P.2    Chiriaco, C.3    Pirritano, D.4    Nistico, R.5
  • 68
    • 0036322886 scopus 로고    scopus 로고
    • Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain
    • Tzourio-Mazoyer N, Landeau B, Papathanassiou D, Crivello F, Etard O, et al. (2002) Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain. Neuroimage 15: 273-289.
    • (2002) Neuroimage , vol.15 , pp. 273-289
    • Tzourio-Mazoyer, N.1    Landeau, B.2    Papathanassiou, D.3    Crivello, F.4    Etard, O.5
  • 69
    • 0030919952 scopus 로고    scopus 로고
    • Testing for anatomically specified regional effects
    • Friston KJ, (1997) Testing for anatomically specified regional effects. Hum Brain Mapp 5: 133-136.
    • (1997) Hum Brain Mapp , vol.5 , pp. 133-136
    • Friston, K.J.1
  • 70
    • 0029931242 scopus 로고    scopus 로고
    • A unified statistical approach for determining significant signals in images of cerebral activation
    • Worsley KJ, Marrett S, Neelin P, Vandal AC, Friston KJ, et al. (1996) A unified statistical approach for determining significant signals in images of cerebral activation. Human Brain Mapping 4: 58-73.
    • (1996) Human Brain Mapping , vol.4 , pp. 58-73
    • Worsley, K.J.1    Marrett, S.2    Neelin, P.3    Vandal, A.C.4    Friston, K.J.5
  • 71
    • 0038777434 scopus 로고    scopus 로고
    • Modeling regional and psychophysiologic interactions in fMRI: the importance of hemodynamic deconvolution
    • Gitelman DR, Penny WD, Ashburner J, Friston KJ, (2003) Modeling regional and psychophysiologic interactions in fMRI: the importance of hemodynamic deconvolution. Neuroimage 19: 200-207.
    • (2003) Neuroimage , vol.19 , pp. 200-207
    • Gitelman, D.R.1    Penny, W.D.2    Ashburner, J.3    Friston, K.J.4
  • 73
    • 33749995605 scopus 로고    scopus 로고
    • The Met66 allele of the functional Val66Met polymorphism in the brain-derived neurotrophic factor gene confers protection against neurocognitive dysfunction in systemic lupus erythematosus
    • Oroszi G, Lapteva L, Davis E, Yarboro CH, Weickert T, et al. (2006) The Met66 allele of the functional Val66Met polymorphism in the brain-derived neurotrophic factor gene confers protection against neurocognitive dysfunction in systemic lupus erythematosus. Ann Rheum Dis 65: 1330-1335.
    • (2006) Ann Rheum Dis , vol.65 , pp. 1330-1335
    • Oroszi, G.1    Lapteva, L.2    Davis, E.3    Yarboro, C.H.4    Weickert, T.5
  • 74
    • 77955227027 scopus 로고    scopus 로고
    • BDNF gene polymorphism (Val66Met) predicts amygdala and anterior hippocampus responses to emotional faces in anxious and depressed adolescents
    • Lau JY, Goldman D, Buzas B, Hodgkinson C, Leibenluft E, et al. (2010) BDNF gene polymorphism (Val66Met) predicts amygdala and anterior hippocampus responses to emotional faces in anxious and depressed adolescents. Neuroimage 53: 952-961.
    • (2010) Neuroimage , vol.53 , pp. 952-961
    • Lau, J.Y.1    Goldman, D.2    Buzas, B.3    Hodgkinson, C.4    Leibenluft, E.5
  • 75
    • 79951473930 scopus 로고    scopus 로고
    • The brain-derived neurotrophic factor Val66Met polymorphism and prediction of neural risk for Alzheimer disease
    • Voineskos AN, Lerch JP, Felsky D, Shaikh S, Rajji TK, et al. (2011) The brain-derived neurotrophic factor Val66Met polymorphism and prediction of neural risk for Alzheimer disease. Arch Gen Psychiatry 68: 198-206.
    • (2011) Arch Gen Psychiatry , vol.68 , pp. 198-206
    • Voineskos, A.N.1    Lerch, J.P.2    Felsky, D.3    Shaikh, S.4    Rajji, T.K.5


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