Illuminating the activation mechanisms and allosteric properties of metabotropic glutamate receptors

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 15, 2013, Pages

  Doumazane, Etienne ^a,b   Scholler, Pauline ^a,b,c   Fabre, Ludovic ^a,b,c   Zwier, Jurriaan M ^c   Trinquet, Eric ^c   Pin, Jean Philippe ^a,b   Rondard, Philippe ^a,b  

^a INSTITUT DE GÉNOMIQUE FONCTIONNELLE   (France)

^b UNIV MONTPELLIER   (France)

^c Universités de Montpellier 1 and 2 ^*  (France)

Author keywords

Biosensor; Kallostery; Snap tag; Time resolved fret

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; METABOTROPIC RECEPTOR;

ALLOSTERISM; ARTICLE; BIOACCUMULATION; CELL SURFACE; CONFORMATIONAL TRANSITION; COVALENT BOND; EFFECTOR CELL; EXTRACELLULAR SPACE; FLUORESCENCE RESONANCE ENERGY TRANSFER; LIGAND BINDING; LOSS OF FUNCTION MUTATION; MOLECULAR DYNAMICS; MUTATIONAL ANALYSIS; POINT MUTATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN STABILITY;

ALLOSTERIC SITE; ANIMALS; CALCIUM; CELL MEMBRANE; CRYSTALLOGRAPHY, X-RAY; DNA MUTATIONAL ANALYSIS; FLUORESCENCE RESONANCE ENERGY TRANSFER; GLUTAMIC ACID; GTP-BINDING PROTEINS; HEK293 CELLS; HUMANS; LIGANDS; MUTATION; PLASMIDS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN MULTIMERIZATION; RATS; RECEPTORS, METABOTROPIC GLUTAMATE;

EID: 84876065856     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1215615110     Document Type: Article

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