메뉴 건너뛰기




Volumn 288, Issue 14, 2013, Pages 9767-9778

Proliferation rate of somatic cells affects reprogramming efficiency

Author keywords

[No Author keywords available]

Indexed keywords

CELL CYCLE CONTROL; CELL REPLACEMENT THERAPY; COMPLEMENTATION; DRUG SCREENING; MOUSE EMBRYONIC FIBROBLASTS; NEW APPROACHES; PROLIFERATION RATE; SMALL MOLECULE INHIBITOR;

EID: 84875997644     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.403881     Document Type: Article
Times cited : (46)

References (83)
  • 1
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi, K., and Yamanaka, S. (2006) Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126, 663-676
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 2
    • 77958569435 scopus 로고    scopus 로고
    • Induced pluripotency. History, mechanisms, and applications
    • Stadtfeld, M., and Hochedlinger, K. (2010) Induced pluripotency. History, mechanisms, and applications. Genes Dev. 24, 2239-2263
    • (2010) Genes Dev , vol.24 , pp. 2239-2263
    • Stadtfeld, M.1    Hochedlinger, K.2
  • 6
    • 64749111225 scopus 로고    scopus 로고
    • Virus-free induction of pluripotency and subsequent excision of reprogramming factors
    • Kaji, K., Norrby, K., Paca, A., Mileikovsky, M., Mohseni, P., and Woltjen, K. (2009) Virus-free induction of pluripotency and subsequent excision of reprogramming factors. Nature 458, 771-775
    • (2009) Nature , vol.458 , pp. 771-775
    • Kaji, K.1    Norrby, K.2    Paca, A.3    Mileikovsky, M.4    Mohseni, P.5    Woltjen, K.6
  • 8
    • 62949220231 scopus 로고    scopus 로고
    • Molecules that promote or enhance reprogramming of somatic cells to induced pluripotent stem cells
    • Feng, B., Ng, J. H., Heng, J. C., and Ng, H. H. (2009) Molecules that promote or enhance reprogramming of somatic cells to induced pluripotent stem cells. Cell Stem Cell 4, 301-312
    • (2009) Cell Stem Cell , vol.4 , pp. 301-312
    • Feng, B.1    Ng, J.H.2    Heng, J.C.3    Ng, H.H.4
  • 9
    • 72749089194 scopus 로고    scopus 로고
    • Small molecules that modulate embryonic stem cell fate and somatic cell reprogramming
    • Li, W., and Ding, S. (2010) Small molecules that modulate embryonic stem cell fate and somatic cell reprogramming. Trends Pharmacol. Sci. 31, 36-45
    • (2010) Trends Pharmacol. Sci. , vol.31 , pp. 36-45
    • Li, W.1    Ding, S.2
  • 11
    • 16844364151 scopus 로고    scopus 로고
    • LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism
    • Cartwright, P., McLean, C., Sheppard, A., Rivett, D., Jones, K., and Dalton, S. (2005) LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism. Development 132, 885-896
    • (2005) Development , vol.132 , pp. 885-896
    • Cartwright, P.1    McLean, C.2    Sheppard, A.3    Rivett, D.4    Jones, K.5    Dalton, S.6
  • 12
    • 56749184298 scopus 로고    scopus 로고
    • Reflecting on 25 years with MYC
    • Meyer, N., and Penn, L. Z. (2008) Reflecting on 25 years with MYC. Nat. Rev. Cancer 8, 976-990
    • (2008) Nat. Rev. Cancer , vol.8 , pp. 976-990
    • Meyer, N.1    Penn, L.Z.2
  • 14
    • 67849092746 scopus 로고    scopus 로고
    • The cell cycle and Myc intersect with mechanisms that regulate pluripotency and reprogramming
    • Singh, A. M., and Dalton, S. (2009) The cell cycle and Myc intersect with mechanisms that regulate pluripotency and reprogramming. Cell Stem Cell 5, 141-149
    • (2009) Cell Stem Cell , vol.5 , pp. 141-149
    • Singh, A.M.1    Dalton, S.2
  • 18
    • 84858200042 scopus 로고    scopus 로고
    • Generation of chimeras by microinjection
    • Plück, A., and Klasen, C. (2009) Generation of chimeras by microinjection. Methods Mol. Biol. 561, 199-217
    • (2009) Methods Mol. Biol. , vol.561 , pp. 199-217
    • Plück, A.1    Klasen, C.2
  • 19
    • 8644231848 scopus 로고    scopus 로고
    • Nuclei of embryonic stem cells reprogram somatic cells
    • Do, J. T., and Schöler, H. R. (2004) Nuclei of embryonic stem cells reprogram somatic cells. Stem Cells 22, 941-949
    • (2004) Stem Cells , vol.22 , pp. 941-949
    • Do, J.T.1    Schöler, H.R.2
  • 21
    • 37549008674 scopus 로고    scopus 로고
    • C-Myc is dispensable for direct reprogramming of mouse fibroblasts
    • Wernig, M., Meissner, A., Cassady, J. P., and Jaenisch, R. (2008) c-Myc is dispensable for direct reprogramming of mouse fibroblasts. Cell Stem Cell 2, 10-12
    • (2008) Cell Stem Cell , vol.2 , pp. 10-12
    • Wernig, M.1    Meissner, A.2    Cassady, J.P.3    Jaenisch, R.4
  • 22
    • 79960046168 scopus 로고    scopus 로고
    • Rational optimization of reprogramming culture conditions for the generation of induced pluripotent stem cells with ultra-high efficiency and fast kinetics
    • Chen, J., Liu, J., Chen, Y., Yang, J., Chen, J., Liu, H., Zhao, X., Mo, K., Song, H., Guo, L., Chu, S., Wang, D., Ding, K., and Pei, D. (2011) Rational optimization of reprogramming culture conditions for the generation of induced pluripotent stem cells with ultra-high efficiency and fast kinetics. Cell Res. 21, 884-894
    • (2011) Cell Res , vol.21 , pp. 884-894
    • Chen, J.1    Liu, J.2    Chen, Y.3    Yang, J.4    Chen, J.5    Liu, H.6    Zhao, X.7    Mo, K.8    Song, H.9    Guo, L.10    Chu, S.11    Wang, D.12    Ding, K.13    Pei, D.14
  • 24
    • 36749085334 scopus 로고    scopus 로고
    • The world according to MYC. Conference on MYC and the transcriptional control of proliferation and oncogenesis
    • Lüscher, B., and Larsson, L. G. (2007) The world according to MYC. Conference on MYC and the transcriptional control of proliferation and oncogenesis. EMBO Rep. 8, 1110-1114
    • (2007) EMBO Rep , vol.8 , pp. 1110-1114
    • Lüscher, B.1    Larsson, L.G.2
  • 25
  • 26
    • 84862220003 scopus 로고    scopus 로고
    • Coordination of cell cycle and differentiation in the developing nervous system
    • Hindley, C., and Philpott, A. (2012) Coordination of cell cycle and differentiation in the developing nervous system. Biochem. J. 444, 375-382
    • (2012) Biochem. J. , vol.444 , pp. 375-382
    • Hindley, C.1    Philpott, A.2
  • 27
    • 37549000146 scopus 로고    scopus 로고
    • Interweaving the cell cycle machinery with cell differentiation
    • Miller, J. P., Yeh, N., Vidal, A., and Koff, A. (2007) Interweaving the cell cycle machinery with cell differentiation. Cell Cycle 6, 2932-2938
    • (2007) Cell Cycle , vol.6 , pp. 2932-2938
    • Miller, J.P.1    Yeh, N.2    Vidal, A.3    Koff, A.4
  • 28
    • 84859171807 scopus 로고    scopus 로고
    • MYC on the path to cancer
    • Dang, C. V. (2012) MYC on the path to cancer. Cell 149, 22-35
    • (2012) Cell , vol.149 , pp. 22-35
    • Dang, C.V.1
  • 29
    • 0034213414 scopus 로고    scopus 로고
    • N-myc can functionally replace c-myc in murine development, cellular growth, and differentiation
    • Malynn, B. A., de Alboran, I. M., O'Hagan, R. C., Bronson, R., Davidson, L., DePinho, R. A., and Alt, F. W. (2000) N-myc can functionally replace c-myc in murine development, cellular growth, and differentiation. Genes Dev. 14, 1390-1399
    • (2000) Genes Dev , vol.14 , pp. 1390-1399
    • Malynn, B.A.1    De Alboran, I.M.2    O'Hagan, R.C.3    Bronson, R.4    Davidson, L.5    Depinho, R.A.6    Alt, F.W.7
  • 30
    • 0037108268 scopus 로고    scopus 로고
    • N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation
    • Knoepfler, P. S., Cheng, P. F., and Eisenman, R. N. (2002) N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation. Genes Dev. 16, 2699-2712
    • (2002) Genes Dev , vol.16 , pp. 2699-2712
    • Knoepfler, P.S.1    Cheng, P.F.2    Eisenman, R.N.3
  • 31
    • 0022468529 scopus 로고
    • Constitutive c-myc oncogene expression blocks mouse erythroleukaemia cell differentiation but not commitment
    • Coppola, J. A., and Cole, M. D. (1986) Constitutive c-myc oncogene expression blocks mouse erythroleukaemia cell differentiation but not commitment. Nature 320, 760-763
    • (1986) Nature , vol.320 , pp. 760-763
    • Coppola, J.A.1    Cole, M.D.2
  • 32
    • 0023022625 scopus 로고
    • The c-myc oncogene perturbs B lymphocyte development in E-mu-myc transgenic mice
    • Langdon, W. Y., Harris, A. W., Cory, S., and Adams, J. M. (1986) The c-myc oncogene perturbs B lymphocyte development in E-mu-myc transgenic mice. Cell 47, 11-18
    • (1986) Cell , vol.47 , pp. 11-18
    • Langdon, W.Y.1    Harris, A.W.2    Cory, S.3    Adams, J.M.4
  • 34
    • 0030778620 scopus 로고    scopus 로고
    • C-Myc promotes differentiation of human epidermal stem cells
    • Gandarillas, A., and Watt, F. M. (1997) c-Myc promotes differentiation of human epidermal stem cells. Genes Dev. 11, 2869-2882
    • (1997) Genes Dev , vol.11 , pp. 2869-2882
    • Gandarillas, A.1    Watt, F.M.2
  • 37
    • 0035856918 scopus 로고    scopus 로고
    • C-Myc regulates mammalian body size by controlling cell number but not cell size
    • Trumpp, A., Refaeli, Y., Oskarsson, T., Gasser, S., Murphy, M., Martin, G. R., and Bishop, J. M. (2001) c-Myc regulates mammalian body size by controlling cell number but not cell size. Nature 414, 768-773
    • (2001) Nature , vol.414 , pp. 768-773
    • Trumpp, A.1    Refaeli, Y.2    Oskarsson, T.3    Gasser, S.4    Murphy, M.5    Martin, G.R.6    Bishop, J.M.7
  • 39
    • 67649857200 scopus 로고    scopus 로고
    • The role of senescence and prosurvival signaling in controlling the oncogenic activity of FGFR2 mutants associated with cancer and birth defects
    • Ota, S., Zhou, Z. Q., Link, J. M., and Hurlin, P. J. (2009) The role of senescence and prosurvival signaling in controlling the oncogenic activity of FGFR2 mutants associated with cancer and birth defects. Hum. Mol. Genet. 18, 2609-2621
    • (2009) Hum. Mol. Genet. , vol.18 , pp. 2609-2621
    • Ota, S.1    Zhou, Z.Q.2    Link, J.M.3    Hurlin, P.J.4
  • 46
    • 79952538234 scopus 로고    scopus 로고
    • Reprogramming to pluripotency. Stepwise resetting of the epigenetic landscape
    • Papp, B., and Plath, K. (2011) Reprogramming to pluripotency. Stepwise resetting of the epigenetic landscape. Cell Res. 21, 486-501
    • (2011) Cell Res , vol.21 , pp. 486-501
    • Papp, B.1    Plath, K.2
  • 47
    • 54949115497 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds
    • Shi, Y., Desponts, C., Do, J. T., Hahm, H. S., Schöler, H. R., and Ding, S. (2008) Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds. Cell Stem Cell 3, 568-574
    • (2008) Cell Stem Cell , vol.3 , pp. 568-574
    • Shi, Y.1    Desponts, C.2    Do, J.T.3    Hahm, H.S.4    Schöler, H.R.5    Ding, S.6
  • 48
    • 44349103591 scopus 로고    scopus 로고
    • A combined chemical and genetic approach for the generation of induced pluripotent stem cells
    • Shi, Y., Do, J. T., Desponts, C., Hahm, H. S., Schöler, H. R., and Ding, S. (2008) A combined chemical and genetic approach for the generation of induced pluripotent stem cells. Cell Stem Cell 2, 525-528
    • (2008) Cell Stem Cell , vol.2 , pp. 525-528
    • Shi, Y.1    Do, J.T.2    Desponts, C.3    Hahm, H.S.4    Schöler, H.R.5    Ding, S.6
  • 50
    • 33645086120 scopus 로고    scopus 로고
    • Functional diversity of DNA methyltransferase inhibitors in human cancer cell lines
    • Stresemann, C., Brueckner, B., Musch, T., Stopper, H., and Lyko, F. (2006) Functional diversity of DNA methyltransferase inhibitors in human cancer cell lines. Cancer Res. 66, 2794-2800
    • (2006) Cancer Res , vol.66 , pp. 2794-2800
    • Stresemann, C.1    Brueckner, B.2    Musch, T.3    Stopper, H.4    Lyko, F.5
  • 51
    • 0025217484 scopus 로고
    • Effects of calcium channel modulators on the proliferation of mouse spleen lymphocytes in vitro
    • Kunert-Radek, J., Stepien, H., Lyson, K., and Pawlikowski, M. (1990) Effects of calcium channel modulators on the proliferation of mouse spleen lymphocytes in vitro. Agents Actions 29, 254-258
    • (1990) Agents Actions , vol.29 , pp. 254-258
    • Kunert-Radek, J.1    Stepien, H.2    Lyson, K.3    Pawlikowski, M.4
  • 54
    • 0033152122 scopus 로고    scopus 로고
    • Discovery and initial characterization of the paullones, a novel class of small-molecule inhibitors of cyclin-dependent kinases
    • Zaharevitz, D. W., Gussio, R., Leost, M., Senderowicz, A. M., Lahusen, T., Kunick, C., Meijer, L., and Sausville, E. A. (1999) Discovery and initial characterization of the paullones, a novel class of small-molecule inhibitors of cyclin-dependent kinases. Cancer Res. 59, 2566-2569
    • (1999) Cancer Res. , vol.59 , pp. 2566-2569
    • Zaharevitz, D.W.1    Gussio, R.2    Leost, M.3    Senderowicz, A.M.4    Lahusen, T.5    Kunick, C.6    Meijer, L.7    Sausville, E.A.8
  • 57
    • 33746883106 scopus 로고    scopus 로고
    • Chronic administration of valproic acid inhibits prostate cancer cell growth in vitro and in vivo
    • Xia, Q., Sung, J., Chowdhury, W., Chen, C. L., Höti, N., Shabbeer, S., Carducci, M., and Rodriguez, R. (2006) Chronic administration of valproic acid inhibits prostate cancer cell growth in vitro and in vivo. Cancer Res. 66, 7237-7244
    • (2006) Cancer Res , vol.66 , pp. 7237-7244
    • Xia, Q.1    Sung, J.2    Chowdhury, W.3    Chen, C.L.4    Höti, N.5    Shabbeer, S.6    Carducci, M.7    Rodriguez, R.8
  • 59
    • 0032694596 scopus 로고    scopus 로고
    • Inhibitors of histone deacetylase suppress the growth of MCF-7 breast cancer cells
    • Schmidt, K., Gust, R., and Jung, M. (1999) Inhibitors of histone deacetylase suppress the growth of MCF-7 breast cancer cells. Arch. Pharm. (Weinheim) 332, 353-357
    • (1999) Arch. Pharm. (Weinheim) , vol.332 , pp. 353-357
    • Schmidt, K.1    Gust, R.2    Jung, M.3
  • 60
    • 0030796349 scopus 로고    scopus 로고
    • Induction of caspase-3 protease activity and apoptosis by butyrate and trichostatin A (inhibitors of histone deacetylase). Dependence on protein synthesis and synergy with a mitochondrial/cytochrome c-dependent pathway
    • Medina, V., Edmonds, B., Young, G. P., James, R., Appleton, S., and Zalewski, P. D. (1997) Induction of caspase-3 protease activity and apoptosis by butyrate and trichostatin A (inhibitors of histone deacetylase). Dependence on protein synthesis and synergy with a mitochondrial/cytochrome c-dependent pathway. Cancer Res. 57, 3697-3707
    • (1997) Cancer Res , vol.57 , pp. 3697-3707
    • Medina, V.1    Edmonds, B.2    Young, G.P.3    James, R.4    Appleton, S.5    Zalewski, P.D.6
  • 61
    • 0034665124 scopus 로고    scopus 로고
    • Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, suppresses the growth of prostate cancer cells in vitro and in vivo
    • Butler, L. M., Agus, D. B., Scher, H. I., Higgins, B., Rose, A., Cordon-Cardo, C., Thaler, H. T., Rifkind, R. A., Marks, P. A., and Richon, V. M. (2000) Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, suppresses the growth of prostate cancer cells in vitro and in vivo. Cancer Res. 60, 5165-5170
    • (2000) Cancer Res , vol.60 , pp. 5165-5170
    • Butler, L.M.1    Agus, D.B.2    Scher, H.I.3    Higgins, B.4    Rose, A.5    Cordon-Cardo, C.6    Thaler, H.T.7    Rifkind, R.A.8    Marks, P.A.9    Richon, V.M.10
  • 62
    • 0035046529 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors. Development of suberoylanilide hydroxamic acid (SAHA) for the treatment of cancers
    • Richon, V. M., Zhou, X., Rifkind, R. A., and Marks, P. A. (2001) Histone deacetylase inhibitors. Development of suberoylanilide hydroxamic acid (SAHA) for the treatment of cancers. Blood Cells Mol. Dis. 27, 260-264
    • (2001) Blood Cells Mol. Dis. , vol.27 , pp. 260-264
    • Richon, V.M.1    Zhou, X.2    Rifkind, R.A.3    Marks, P.A.4
  • 63
    • 20444479514 scopus 로고    scopus 로고
    • Drug insight. Histone deacetylase inhibitors. Development of the new targeted anticancer agent suberoylanilide hydroxamic acid
    • Kelly, W. K., and Marks, P. A. (2005) Drug insight. Histone deacetylase inhibitors. Development of the new targeted anticancer agent suberoylanilide hydroxamic acid. Nat. Clin. Pract. Oncol. 2, 150-157
    • (2005) Nat. Clin. Pract. Oncol. , vol.2 , pp. 150-157
    • Kelly, W.K.1    Marks, P.A.2
  • 64
    • 0027478676 scopus 로고
    • Induction of replicative senescence by 5-azacytidine. Fundamental cell kinetic differences between human diploid fibroblasts and NIH-3T3 cells
    • Weller, E. M., Poot, M., and Hoehn, H. (1993) Induction of replicative senescence by 5-azacytidine. Fundamental cell kinetic differences between human diploid fibroblasts and NIH-3T3 cells. Cell Prolif 26, 45-54
    • (1993) Cell Prolif , vol.26 , pp. 45-54
    • Weller, E.M.1    Poot, M.2    Hoehn, H.3
  • 65
    • 0032880837 scopus 로고    scopus 로고
    • Effects of dexamethasone on proliferation, activity, and cytokine secretion of normal human bone marrow stromal cells. Possible mechanisms of glucocorticoid-induced bone loss
    • Kim, C. H., Cheng, S. L., and Kim, G. S. (1999) Effects of dexamethasone on proliferation, activity, and cytokine secretion of normal human bone marrow stromal cells. Possible mechanisms of glucocorticoid-induced bone loss. J. Endocrinol. 162, 371-379
    • (1999) J. Endocrinol. , vol.162 , pp. 371-379
    • Kim, C.H.1    Cheng, S.L.2    Kim, G.S.3
  • 66
    • 62949155029 scopus 로고    scopus 로고
    • Dexamethasone inhibits proliferation and stimulates SSeCKS expression in C6 rat glioma cell line
    • Liu, H., Huang, X., Wang, H., Shen, A., and Cheng, C. (2009) Dexamethasone inhibits proliferation and stimulates SSeCKS expression in C6 rat glioma cell line. Brain Res. 1265, 1-12
    • (2009) Brain Res. , vol.1265 , pp. 1-12
    • Liu, H.1    Huang, X.2    Wang, H.3    Shen, A.4    Cheng, C.5
  • 67
    • 34547136486 scopus 로고    scopus 로고
    • Dexamethasone inhibits proliferation and stimulates ecto-5′- nucleotidase/CD73 activity in C6 rat glioma cell line
    • Bavaresco, L., Bernardi, A., Braganhol, E., Wink, M. R., and Battastini, A. M. (2007) Dexamethasone inhibits proliferation and stimulates ecto-5′-nucleotidase/CD73 activity in C6 rat glioma cell line. J. Neurooncol. 84, 1-8
    • (2007) J. Neurooncol. , vol.84 , pp. 1-8
    • Bavaresco, L.1    Bernardi, A.2    Braganhol, E.3    Wink, M.R.4    Battastini, A.M.5
  • 68
    • 33846426812 scopus 로고    scopus 로고
    • Dexamethasone inhibits epidermal growth factor-stimulated gastric epithelial cell proliferation
    • Luo, J. C., Chi, C. W., Lin, H. Y., Chang, F. Y., Lu, C. L., Chen, C. Y., and Lee, S. D. (2007) Dexamethasone inhibits epidermal growth factor-stimulated gastric epithelial cell proliferation. J. Pharmacol. Exp. Ther. 320, 687-694
    • (2007) J. Pharmacol. Exp. Ther. , vol.320 , pp. 687-694
    • Luo, J.C.1    Chi, C.W.2    Lin, H.Y.3    Chang, F.Y.4    Lu, C.L.5    Chen, C.Y.6    Lee, S.D.7
  • 70
    • 70449348455 scopus 로고    scopus 로고
    • Wnt signaling promotes proliferation and stemness regulation of spermatogonial stem/progenitor cells
    • Golestaneh, N., Beauchamp, E., Fallen, S., Kokkinaki, M., Uren, A., and Dym, M. (2009) Wnt signaling promotes proliferation and stemness regulation of spermatogonial stem/progenitor cells. Reproduction 138, 151-162
    • (2009) Reproduction , vol.138 , pp. 151-162
    • Golestaneh, N.1    Beauchamp, E.2    Fallen, S.3    Kokkinaki, M.4    Uren, A.5    Dym, M.6
  • 71
    • 35648981937 scopus 로고    scopus 로고
    • Wnt3a signaling promotes proliferation, myogenic differentiation, and migration of rat bone marrow mesenchymal stem cells
    • Shang, Y. C., Wang, S. H., Xiong, F., Zhao, C. P., Peng, F. N., Feng, S. W., Li, M. S., Li, Y., and Zhang, C. (2007) Wnt3a signaling promotes proliferation, myogenic differentiation, and migration of rat bone marrow mesenchymal stem cells. Acta Pharmacol. Sin. 28, 1761-1774
    • (2007) Acta Pharmacol. Sin. , vol.28 , pp. 1761-1774
    • Shang, Y.C.1    Wang, S.H.2    Xiong, F.3    Zhao, C.P.4    Peng, F.N.5    Feng, S.W.6    Li, M.S.7    Li, Y.8    Zhang, C.9
  • 75
    • 29644443725 scopus 로고    scopus 로고
    • The ALK-5 inhibitor A-83-01 inhibits Smad signaling and epithelial-to-mesenchymal transition by transforming growth factor-β
    • Tojo, M., Hamashima, Y., Hanyu, A., Kajimoto, T., Saitoh, M., Miyazono, K., Node, M., and Imamura, T. (2005) The ALK-5 inhibitor A-83-01 inhibits Smad signaling and epithelial-to-mesenchymal transition by transforming growth factor-β. Cancer Sci. 96, 791-800
    • (2005) Cancer Sci , vol.96 , pp. 791-800
    • Tojo, M.1    Hamashima, Y.2    Hanyu, A.3    Kajimoto, T.4    Saitoh, M.5    Miyazono, K.6    Node, M.7    Imamura, T.8
  • 78
    • 10344258041 scopus 로고    scopus 로고
    • Targeting the mitogen-activated protein kinase cascade to treat cancer
    • Sebolt-Leopold, J. S., and Herrera, R. (2004) Targeting the mitogen-activated protein kinase cascade to treat cancer. Nat. Rev. Cancer 4, 937-947
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 937-947
    • Sebolt-Leopold, J.S.1    Herrera, R.2
  • 82
    • 0026665210 scopus 로고
    • Growth inhibitory and differentiating effects of sodium butyrate on human neuroblastoma cells in culture
    • Rocchi, P., Ferreri, A. M., Simone, G., Granchi, D., Paolucci, P., and Paolucci, G. (1992) Growth inhibitory and differentiating effects of sodium butyrate on human neuroblastoma cells in culture. Anticancer Res. 12, 917-920
    • (1992) Anticancer Res. , vol.12 , pp. 917-920
    • Rocchi, P.1    Ferreri, A.M.2    Simone, G.3    Granchi, D.4    Paolucci, P.5    Paolucci, G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.