Dimerization of bacterial diaminopimelate epimerase is essential for catalysis

Journal of Biological Chemistry

Volumn 288, Issue 13, 2013, Pages 9238-9248

  Hor, Lilian ^a,b,c   Dobson, Renwick C J ^b,c,d   Downton, Matthew T ^b   Wagner, John ^b   Hutton, Craig A ^b,c   Perugini, Matthew A ^a,b,c  

^a LA TROBE UNIVERSITY   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d UNIVERSITY OF CANTERBURY   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

ANALYTICAL ULTRACENTRIFUGATION; ANTIMICROBIAL TARGETS; MOLECULAR DYNAMICS SIMULATIONS; MONOMERIC ENZYMES; SITE DIRECTED MUTAGENESIS; SUPPORT FUNCTIONS; VIRULENCE FACTORS; X RAY CRYSTAL STRUCTURES;

AMINO ACIDS; BIOCHEMISTRY; CATALYSIS; CENTRIFUGATION; DIMERIZATION; ENZYMES; ESCHERICHIA COLI; MOLECULAR DYNAMICS; PROTEINS; X RAY CRYSTALLOGRAPHY;

DIMERS;

BACTERIAL ENZYME; DIAMINOPIMELATE EPIMERASE; DIMER; MONOMER; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; DIMERIZATION; ENZYME CONFORMATION; ENZYME KINETICS; ENZYME MODIFICATION; ESCHERICHIA COLI; MOLECULAR DYNAMICS; MUTANT; NONHUMAN; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; STRUCTURE ANALYSIS; ULTRACENTRIFUGATION; X RAY CRYSTALLOGRAPHY;

AMINO ACID ISOMERASES; ANTI-BACTERIAL AGENTS; CATALYTIC DOMAIN; CIRCULAR DICHROISM; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; ESCHERICHIA COLI; LYSINE; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR DYNAMICS SIMULATION; MUTAGENESIS, SITE-DIRECTED; MUTATION; POINT MUTATION; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 84875984163     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.450148     Document Type: Article

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