Properties of GDP-mannose Pyrophosphorylase, a Critical Enzyme and Drug Target in Leishmania mexicana

Journal of Biological Chemistry

Volumn 279, Issue 13, 2004, Pages 12462-12468

  Davis, Antony J ^a   Perugini, Matthew A ^b   Smith, Brian J ^a   Stewart, James D ^a   Ilg, Thomas ^c   Hodder, Anthony N ^a   Handman, Emanuela ^a  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c Intervet Innovation GmbH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINITY; DRUG PRODUCTS; FLUORESCENCE; FUNGI; IMMUNOLOGY; IONIC STRENGTH;

MOLECULE INHIBITORS; SUBCELLULAR FRACTIONATION;

ENZYMES;

GLYCOCONJUGATE; GUANOSINE DIPHOSPHATE MANNOSE; GUANOSINE DIPHOSPHATE MANNOSE PYROPHOSPHORYLASE; GUANOSINE TRIPHOSPHATE; MALTOSE BINDING PROTEIN; MANNOSE PHOSPHATE; PHOSPHORYLASE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL VIRULENCE; CATALYSIS; CELL FRACTIONATION; CIRCULAR DICHROISM; COLORIMETRY; DRUG TARGETING; ENZYME ACTIVITY; ENZYME METABOLISM; GEL PERMEATION CHROMATOGRAPHY; LEISHMANIA MEXICANA; LEISHMANIASIS; NONHUMAN; PARASITE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN TARGETING; PROTOZOAL INFECTION; PSYCHODIDAE; SCREENING; ULTRACENTRIFUGATION;

ANIMALS; ANTIPROTOZOAL AGENTS; BLOTTING, WESTERN; CARRIER PROTEINS; CATALYSIS; CHROMATOGRAPHY, ION EXCHANGE; CIRCULAR DICHROISM; CYTOPLASM; DETERGENTS; GENE DELETION; HYDROGEN-ION CONCENTRATION; LEISHMANIA MEXICANA; MICROSCOPY, FLUORESCENCE; MODELS, CHEMICAL; NUCLEOTIDYLTRANSFERASES; PHENOTYPE; POLYETHYLENE GLYCOLS; PRECIPITIN TESTS; RECOMBINANT PROTEINS; STREPTOCOCCUS PNEUMONIAE; SUBCELLULAR FRACTIONS; TIME FACTORS; WATER;

BACTERIA (MICROORGANISMS); FUNGI; LEISHMANIA MEXICANA; MAMMALIA; PROTOZOA; PSYCHODIDAE; STREPTOCOCCUS; STREPTOCOCCUS PNEUMONIAE;

EID: 1842425027     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M312365200     Document Type: Article

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