Atomic resolution structure of the orotidine 5′-monophosphate decarboxylase product complex combined with surface plasmon resonance analysis: Implications for the catalytic mechanism

Journal of Biological Chemistry

Volumn 288, Issue 13, 2013, Pages 9011-9016

  Fujihashi, Masahiro ^a   Mito, Kazuya ^a   Pai, Emil F ^b,c   Miki, Kunio ^a  

^a KYOTO UNIVERSITY   (Japan)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ATOMIC RESOLUTION; ATOMIC RESOLUTION STRUCTURES; CARBOXYLATE SUBSTITUENTS; CATALYTIC LYSINE; CATALYTIC MECHANISMS; CATALYTIC REACTION MECHANISM; ORDERS OF MAGNITUDE; SURFACE PLASMONS;

AMINO ACIDS; BINDING ENERGY; CARBOXYLATION; PLASMONS; QUANTUM CHEMISTRY; SURFACE PLASMON RESONANCE;

CATALYSIS;

LYSINE; OROTIDINE 5' PHOSPHATE DECARBOXYLASE; URIDINE PHOSPHATE;

ARTICLE; ATOMIC RESOLUTION STRUCTURE; BINDING AFFINITY; BINDING COMPETITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DECARBOXYLATION; ENZYME ACTIVE SITE; ENZYME KINETICS; ENZYME MECHANISM; ENZYME STRUCTURE; ENZYME SUBSTRATE DISTORTION; MOLECULAR INTERACTION; PRIORITY JOURNAL; REPULSIVE INTERACTION; STRUCTURE ANALYSIS; SURFACE PLASMON RESONANCE; WILD TYPE;

BINDING SITES; CATALYSIS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; ELECTRONS; ESCHERICHIA COLI; KINETICS; LIGANDS; METHANOBACTERIACEAE; MODELS, CHEMICAL; MOLECULAR CONFORMATION; MUTATION; OROTIDINE-5'-PHOSPHATE DECARBOXYLASE; PYRIMIDINES; SUBSTRATE SPECIFICITY; SURFACE PLASMON RESONANCE; URIDINE MONOPHOSPHATE;

EID: 84875978950     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.427252     Document Type: Article

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