A Raman-active competitive inhibitor of OMP decarboxylase

Bioorganic Chemistry

Volumn 34, Issue 2, 2006, Pages 59-65

  Callahan, Brian P ^a   Bell, Alasdair F ^b   Tonge, Peter J ^b   Wolfenden, Richard ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b STONY BROOK UNIVERSITY   (United States)

Author keywords

Catalysis; Decarboxylation; Ground state destabilization; Nitrile group; ODCase; OMP decarboxylase; Raman spectroscopy

Indexed keywords

2 PROPANOL; 6 CYANO 1,3 DIMETHYLURACIL; 6 CYANOURIDINE 5' PHOSPHATE; FORMAMIDE; LIGAND; NITRILE; OROTIDINE 5' PHOSPHATE DECARBOXYLASE; PYRIMIDINE; UNCLASSIFIED DRUG; URACIL DERIVATIVE; URIDINE DERIVATIVE;

ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; COMPETITIVE INHIBITION; DECARBOXYLATION; ENZYME INHIBITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; RAMAN SPECTROMETRY; YEAST;

CATALYSIS; ENZYME INHIBITORS; OROTIDINE-5'-PHOSPHATE DECARBOXYLASE; SPECTRUM ANALYSIS, RAMAN;

EID: 33644936395     PISSN: 00452068     EISSN: 10902120     Source Type: Journal    
DOI: 10.1016/j.bioorg.2005.12.001     Document Type: Article

References (23)

1. A. Radzicka, and R. Wolfenden Science 267 1995 90 93
2. B.G. Miller, M.J. Snider, S.A. Short, and R. Wolfenden Biochemistry 39 2000 8113 8118
3. S.A. Acheson, J.B. Bell, M.E. Jones, and R. Wolfenden Biochemistry 29 1990 3198 3202
4. H.L. Levine, R.S. Brody, and F.H. Westheimer Biochemistry 19 1980 4993 4999
5. B.P. Callahan, and R. Wolfenden J. Am. Chem. Soc. 126 2004 14698 14699
6. P.W. Landesman, Ph.D. Thesis, S.U.N.Y. at Buffalo, New York, 1982.
7. B.P. Callahan, Ph.D. Thesis, U.N.C. at Chapel Hill, North Carolina, 2005.
8. Z. Getahun, C.Y. Huang, T. Wang, B. De Leon, W.F. DeGrado, and F. Gai J. Am. Chem. Soc. 125 2003 405 411
9. R.A. Nyquist Appl. Spectrosc. 44 1990 1405 1408
10. J.R. Reimers, and L.E. Hall J. Am. Chem. Soc. 121 1999 3730 3744
11. B.G. Miller, M.J. Snider, R. Wolfenden, and S.A. Short J. Biol. Chem. 276 2001 15174 15176
12. B.G. Miller, A.M. Hassell, R. Wolfenden, M.V. Milburn, and S.A. Short Proc. Natl. Acad. Sci. USA 97 2000 2011 2016
13. N. Wu, W. Gillon, and E.F. Pai Biochemistry 41 2002 4002 4011
14. M.T. Torres, R. Wolfenden, unpublished observation.
15. B.G. Miller, and R. Wolfenden Annu. Rev. Biochem. 71 2002 847 885
16. B.G. Miller, G.L. Butterfoss, S.A. Short, and R. Wolfenden Biochemistry 40 2002 6227 6232
17. A. Sievers, and R. Wolfenden Bioorg. Chem. 33 2005 45 52
18. W.P. Jencks Adv. Enzymol. Relat. Areas Mol. Biol. 43 1975 219
19. A. Warshel, M. Strajbl, J. Villa, and J. Florian Biochemistry 39 2000 14728 14738
20. B.P. Callahan, and R. Wolfenden J. Am. Chem. Soc. 126 2004 4514 4515
21. A. Sievers, and R. Wolfenden J. Am. Chem. Soc. 124 2002 13986 13987
22. A.F. Bell, X. He, R.M. Wachter, and P.J. Tonge Biochemistry 39 2000 4423 4431
23. M.J. Frisch, G.W. Trucks, H.B. Schlegel, G.E. Scuseria, M.A. Robb, J.R. Cheeseman, V.G. Zakrzewski, J.A. Montgomery Jr., R.E. Stratmann, J.C. Burant, S. Dapprich, J.M. Millam, A.D. Daniels, K.N. Kudin, M.C. Strain, O. Farkas, J. Tomasi, V. Barone, M. Cossi, R. Cammi, B. Mennucci, C. Pomelli, C. Adamo, S. Clifford, J. Ochterski, G.A. Petersson, P.Y. Ayala, Q. Cui, K. Morokuma, P. Salvador, J.J. Dannenberg, D.K. Malick, A.D. Rabuck, K. Raghavachari, J.B. Foresman, J. Cioslowski, J.V. Ortiz, A.G. Baboul, B.B. Stefanov, G. Liu, A. Liashenko, P. Piskorz, I. Komaromi, R. Gomperts, R.L. Martin, D.J. Fox, T. Keith, M.A. Al-Laham, C.Y. Peng, A. Nanayakkara, M. Challacombe, P.M.W. Gill, B. Johnson, W. Chen, M.W. Wong, J.L. Andres, C. Gonzalez, M. Head-Gordon, E.S. Replogle, J.A. Pople, Gaussian98, Gaussian, Inc., Pittsburgh, PA, 1998.