Substrate specificity of clostridial glucosylating toxins and their function on colonocytes analyzed by proteomics techniques

Journal of Proteome Research

Volumn 12, Issue 4, 2013, Pages 1604-1618

  Zeiser, Johannes ^a   Gerhard, Ralf ^a   Just, Ingo ^a   Pich, Andreas ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Clostridium difficile; glucosylation; LC MS; SILAC; small GTPases; toxin A; toxin B

Indexed keywords

CLOSTRIDIUM DIFFICILE TOXIN A; CLOSTRIDIUM DIFFICILE TOXIN B; GLUCOSYLTRANSFERASE; GUANOSINE TRIPHOSPHATASE; RAS PROTEIN; REACTIVE OXYGEN METABOLITE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

ACTIN FILAMENT; ACTIN POLYMERIZATION; AMINO ACID ANALYSIS; AMINO ACID SEQUENCE; ARTICLE; CELL ADHESION; CELL CYCLE; CELL CYCLE ARREST; CELL CYCLE PROGRESSION; CELL JUNCTION; CELL STRAIN CACO 2; CELL STRUCTURE; CHOLESTEROL METABOLISM; CLOSTRIDIA; CYTOSKELETON; ENDOCYTOSIS; ENZYME ACTIVITY; ENZYME SPECIFICITY; EPITHELIUM CELL; FATTY ACID METABOLISM; GLYCOSYLATION; LIPID METABOLISM; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MITOCHONDRIAL RESPIRATION; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN INTERACTION;

BACTERIAL PROTEINS; BACTERIAL TOXINS; CACO-2 CELLS; CLOSTRIDIUM DIFFICILE; ENTEROTOXINS; GLYCOSYLATION; HOST-PATHOGEN INTERACTIONS; HUMANS; PROTEINS; PROTEOMICS; RAP GTP-BINDING PROTEINS; RAP1 GTP-BINDING PROTEINS; RHO GTP-BINDING PROTEINS; RHOA GTP-BINDING PROTEIN; SUBSTRATE SPECIFICITY; TANDEM MASS SPECTROMETRY;

CLOSTRIDIUM DIFFICILE;

EID: 84875921606     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr300973q     Document Type: Article

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