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Volumn 74, Issue 10, 2006, Pages 6006-6010

Application of mutated Clostridium difficile toxin A for determination of glucosyltransferase-dependent effects

Author keywords

[No Author keywords available]

Indexed keywords

CLOSTRIDIUM DIFFICILE TOXIN A; GLUCOSYLTRANSFERASE; PROTEIN RHOB; RHO FACTOR; TRYPTOPHAN; UNCLASSIFIED DRUG;

EID: 33749257130     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.00545-06     Document Type: Article
Times cited : (31)

References (20)
  • 3
    • 0036377132 scopus 로고    scopus 로고
    • Fluorescent analogs of UDP-glucose and their use in characterizing substrate binding by toxin A from Clostridium difficile
    • Bhattacharyya, S., A. Kerzmann, and A. L. Feig. 2002. Fluorescent analogs of UDP-glucose and their use in characterizing substrate binding by toxin A from Clostridium difficile. Eur. J. Biochem. 269:3425-3432.
    • (2002) Eur. J. Biochem. , vol.269 , pp. 3425-3432
    • Bhattacharyya, S.1    Kerzmann, A.2    Feig, A.L.3
  • 4
    • 0041670743 scopus 로고    scopus 로고
    • Expression of recombinant Clostridium difficile toxin A using the Bacillus megaterium system
    • Burger, S., H. Tatge, F. Hofmann, I. Just, and R. Gerhard. 2003. Expression of recombinant Clostridium difficile toxin A using the Bacillus megaterium system. Biochem. Biophys. Res. Commun. 307:584-588.
    • (2003) Biochem. Biophys. Res. Commun. , vol.307 , pp. 584-588
    • Burger, S.1    Tatge, H.2    Hofmann, F.3    Just, I.4    Gerhard, R.5
  • 5
    • 0034607988 scopus 로고    scopus 로고
    • Involvement of a conserved tryptophan residue in the UDP-glucose binding of large clostridial cytotoxin glycosyltransferases
    • Busch, C., F. Hofmann, R. Gerhard, and K. Aktories. 2000. Involvement of a conserved tryptophan residue in the UDP-glucose binding of large clostridial cytotoxin glycosyltransferases. J. Biol. Chem. 275:13228-13234.
    • (2000) J. Biol. Chem. , vol.275 , pp. 13228-13234
    • Busch, C.1    Hofmann, F.2    Gerhard, R.3    Aktories, K.4
  • 6
    • 0032584665 scopus 로고    scopus 로고
    • A common motif of eukaryotic glycosyltransferases is essential for the enzyme activity of large clostridial cytotoxins
    • Busch, C., F. Hofmann, J. Selzer, J. Munro, D. Jeckel, and K. Aktories. 1998. A common motif of eukaryotic glycosyltransferases is essential for the enzyme activity of large clostridial cytotoxins. J. Biol. Chem. 273:19566-19572.
    • (1998) J. Biol. Chem. , vol.273 , pp. 19566-19572
    • Busch, C.1    Hofmann, F.2    Selzer, J.3    Munro, J.4    Jeckel, D.5    Aktories, K.6
  • 7
    • 0032831781 scopus 로고    scopus 로고
    • Monoglucosylation of RhoA at threonine-37 blocks cytosol-membrane cycling
    • Genth, H., K. Aktories, and I. Just. 1999. Monoglucosylation of RhoA at threonine-37 blocks cytosol-membrane cycling. J. Biol. Chem. 274:29050-29056.
    • (1999) J. Biol. Chem. , vol.274 , pp. 29050-29056
    • Genth, H.1    Aktories, K.2    Just, I.3
  • 8
    • 33646942752 scopus 로고    scopus 로고
    • Cellular stability of Rho-GTPases glucosylated by Clostridium difficile toxin B
    • Genth, H., J. Huelsenbeck, B. Hartmann, F. Hofmann, I. Just, and R. Gerhard. 2006. Cellular stability of Rho-GTPases glucosylated by Clostridium difficile toxin B. FEBS Lett. 580:3565-3569.
    • (2006) FEBS Lett. , vol.580 , pp. 3565-3569
    • Genth, H.1    Huelsenbeck, J.2    Hartmann, B.3    Hofmann, F.4    Just, I.5    Gerhard, R.6
  • 9
    • 12544256902 scopus 로고    scopus 로고
    • Clostridium difficile toxin A induces expression of the stress-induced early gene product RhoB
    • Gerhard, R., H. Tatge, H. Genth, T. Thum, J. Borlak, G. Fritz, and I. Just. 2005. Clostridium difficile toxin A induces expression of the stress-induced early gene product RhoB. J. Biol. Chem. 280:1499-1505.
    • (2005) J. Biol. Chem. , vol.280 , pp. 1499-1505
    • Gerhard, R.1    Tatge, H.2    Genth, H.3    Thum, T.4    Borlak, J.5    Fritz, G.6    Just, I.7
  • 10
  • 13
    • 20444395071 scopus 로고    scopus 로고
    • Clostridium difficile toxin A regulates inducible COX-2 and PGE2 synthesis in colonocytes via reactive oxygen species and activation of p38 MAP kinase
    • Kim, H., S. H. Rhee, E. Kokkotou, X. Na, T. Savidge, M. P. Moyer, C. Pothoulakis, and J. T. LaMont. 2005. Clostridium difficile toxin A regulates inducible COX-2 and PGE2 synthesis in colonocytes via reactive oxygen species and activation of p38 MAP kinase. J. Biol. Chem. 280:21237-21245.
    • (2005) J. Biol. Chem. , vol.280 , pp. 21237-21245
    • Kim, H.1    Rhee, S.H.2    Kokkotou, E.3    Na, X.4    Savidge, T.5    Moyer, M.P.6    Pothoulakis, C.7    LaMont, J.T.8
  • 14
    • 0035066383 scopus 로고    scopus 로고
    • Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
    • Kyriakis, J. M., and J. Avruch. 2003. Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol. Rev. 81:807-869.
    • (2003) Physiol. Rev. , vol.81 , pp. 807-869
    • Kyriakis, J.M.1    Avruch, J.2
  • 16
  • 17
    • 23644460027 scopus 로고    scopus 로고
    • Structural basis for the function of Clostridium difficile toxin B
    • Reinert, D. J., T. Jank, K. Aktories, and G. E. Schulz. 2005. Structural basis for the function of Clostridium difficile toxin B. J. Mol. Biol. 351:973-981.
    • (2005) J. Mol. Biol. , vol.351 , pp. 973-981
    • Reinert, D.J.1    Jank, T.2    Aktories, K.3    Schulz, G.E.4
  • 19
    • 17444366186 scopus 로고    scopus 로고
    • Clostridium difficile toxins: Mechanism of action and role in disease
    • Voth, D. E., and J. Ballard. 2005. Clostridium difficile toxins: mechanism of action and role in disease. Clin. Microbiol. Rev. 18:247-263.
    • (2005) Clin. Microbiol. Rev. , vol.18 , pp. 247-263
    • Voth, D.E.1    Ballard, J.2
  • 20
    • 0036901591 scopus 로고    scopus 로고
    • Substance P-stimulated interleukin-8 expression in human colonic epithelial cells involves Rho family small GTPases
    • Zhao, D., S. Kuhnt-Moore, H. Zeng, A. Pan, J. S. Wu, S. Simeonidis, M. P. Moyer, and C. Pothoulakis. 2002. Substance P-stimulated interleukin-8 expression in human colonic epithelial cells involves Rho family small GTPases. Biochem. J. 368:665-672.
    • (2002) Biochem. J. , vol.368 , pp. 665-672
    • Zhao, D.1    Kuhnt-Moore, S.2    Zeng, H.3    Pan, A.4    Wu, J.S.5    Simeonidis, S.6    Moyer, M.P.7    Pothoulakis, C.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.