Essential role of the glucosyltransferase activity in Clostridium difficile toxin-induced secretion of TNF-α by macrophages

Microbial Pathogenesis

Volumn 46, Issue 6, 2009, Pages 298-305

  Sun, Xingmin ^a   He, Xiangyun ^a   Tzipori, Saul ^a   Gerhard, Ralf ^b   Feng, Hanping ^a  

^a TUFTS UNIVERSITY   (United States)

^b HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Clostridium difficile; Glucosyltransferase; Macrophage; Toxin A (TcdA); Toxin B (TcdB); Tumor necrosis factor alpha (TNF )

Indexed keywords

AMINO ACID; CLATHRIN; CLOSTRIDIUM DIFFICILE TOXIN A; CLOSTRIDIUM DIFFICILE TOXIN B; CYTOCHALASIN D; CYTOKINE; GLUCOSYLTRANSFERASE; LATRUNCULIN B; TOXIN ANTIBODY; TUMOR NECROSIS FACTOR ALPHA;

ACIDIFICATION; ANIMAL CELL; ARTICLE; CELL DISRUPTION; CELL STIMULATION; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM DIFFICILE INFECTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOKINE RESPONSIVE ELEMENT; CYTOSKELETON; ENDOCYTOSIS; ENDOSOME; ENZYME ACTIVITY; HOST CELL; INFLAMMATION; MACROPHAGE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN INDUCTION; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME;

ANIMALS; BACTERIAL PROTEINS; BACTERIAL TOXINS; CELL LINE, TRANSFORMED; CLOSTRIDIUM DIFFICILE; ENTEROCOLITIS, PSEUDOMEMBRANOUS; ENTEROTOXINS; MACROPHAGES; MICE; TUMOR NECROSIS FACTOR-ALPHA;

CLOSTRIDIUM DIFFICILE; MURINAE;

EID: 67349220680     PISSN: 08824010     EISSN: 10961208     Source Type: Journal    
DOI: 10.1016/j.micpath.2009.03.002     Document Type: Article

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