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Volumn 95, Issue 5, 2013, Pages 1033-1040

Molecular and cellular effects of vitamin B12 in brain, myocardium and liver through its role as co-factor of methionine synthase

Author keywords

Cobalamin; Epigenomics; Fetal programming; Methionine synthase; Vitamin B12

Indexed keywords

ANTIBODY; CHIMERIC PROTEIN; CUBILIN; CYANOCOBALAMIN; FOLIC ACID; METHIONINE SYNTHASE; NERVE GROWTH FACTOR; NITROUS OXIDE; OLEOSIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN; SIRTUIN 1; TRANSCOBALAMIN; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME; UNCLASSIFIED DRUG;

EID: 84875828255     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2013.01.020     Document Type: Review
Times cited : (70)

References (61)
  • 1
    • 72649089540 scopus 로고    scopus 로고
    • Advances in the understanding of cobalamin assimilation and metabolism
    • E.V. Quadros Advances in the understanding of cobalamin assimilation and metabolism Br. J. Haematol. 148 2010 195 204
    • (2010) Br. J. Haematol. , vol.148 , pp. 195-204
    • Quadros, E.V.1
  • 2
    • 0041766196 scopus 로고    scopus 로고
    • The many faces of vitamin B12: Catalysis by cobalamin-dependent enzymes
    • R. Banerjee, and S.W. Ragsdale The many faces of vitamin B12: catalysis by cobalamin-dependent enzymes Annu. Rev. Biochem. 72 2003 209 247
    • (2003) Annu. Rev. Biochem. , vol.72 , pp. 209-247
    • Banerjee, R.1    Ragsdale, S.W.2
  • 3
    • 35448972133 scopus 로고    scopus 로고
    • Vascular oxidant stress and inflammation in hyperhomocysteinemia
    • L. Papatheodorou, and N. Weiss Vascular oxidant stress and inflammation in hyperhomocysteinemia Antioxid. Redox Signal. 9 2007 1941 1958
    • (2007) Antioxid. Redox Signal. , vol.9 , pp. 1941-1958
    • Papatheodorou, L.1    Weiss, N.2
  • 4
    • 84864010293 scopus 로고    scopus 로고
    • Nutrition and epigenetics: An interplay of dietary methyl donors, one-carbon metabolism and DNA methylation
    • O.S. Anderson, K.E. Sant, and D.C. Dolinoy Nutrition and epigenetics: an interplay of dietary methyl donors, one-carbon metabolism and DNA methylation J. Nutr. Biochem. 23 2012 853 859
    • (2012) J. Nutr. Biochem. , vol.23 , pp. 853-859
    • Anderson, O.S.1    Sant, K.E.2    Dolinoy, D.C.3
  • 5
    • 33947538533 scopus 로고    scopus 로고
    • Gestational vitamin B deficiency leads to homocysteine-associated brain apoptosis and alters neurobehavioral development in rats
    • S.A. Blaise, E. Nedelec, H. Schroeder, J.M. Alberto, C. Bossenmeyer-Pourié, J.L. Guéant, and J.L. Daval Gestational vitamin B deficiency leads to homocysteine-associated brain apoptosis and alters neurobehavioral development in rats Am. J. Pathol. 170 2007 667 679
    • (2007) Am. J. Pathol. , vol.170 , pp. 667-679
    • Blaise, S.A.1    Nedelec, E.2    Schroeder, H.3    Alberto, J.M.4    Bossenmeyer- Pourié, C.5    Guéant, J.L.6    Daval, J.L.7
  • 7
    • 77951205191 scopus 로고    scopus 로고
    • Acute and long-term nutrient-led modifications of gene expression: Potential role of SIRT1 as a central co-ordinator of short and longer-term programming of tissue function
    • M.J. Holness, P.W. Caton, and M.C. Sugden Acute and long-term nutrient-led modifications of gene expression: potential role of SIRT1 as a central co-ordinator of short and longer-term programming of tissue function Nutrition 26 2010 491 501
    • (2010) Nutrition , vol.26 , pp. 491-501
    • Holness, M.J.1    Caton, P.W.2    Sugden, M.C.3
  • 11
    • 80054724208 scopus 로고    scopus 로고
    • Fattening by deprivation: Methyl balance and perinatal cardiomyopathy
    • J. Joseph Fattening by deprivation: methyl balance and perinatal cardiomyopathy J. Pathol. 225 2011 315 317
    • (2011) J. Pathol. , vol.225 , pp. 315-317
    • Joseph, J.1
  • 13
    • 79956331144 scopus 로고    scopus 로고
    • Down-regulation of transcobalamin receptor TCblR/CD320 by siRNA inhibits cobalamin uptake and proliferation of cells in culture
    • S.C. Lai, Y. Nakayama, J.M. Sequeira, and E.V. Quadros Down-regulation of transcobalamin receptor TCblR/CD320 by siRNA inhibits cobalamin uptake and proliferation of cells in culture Exp. Cell Res. 317 2011 1603 1607
    • (2011) Exp. Cell Res. , vol.317 , pp. 1603-1607
    • Lai, S.C.1    Nakayama, Y.2    Sequeira, J.M.3    Quadros, E.V.4
  • 15
    • 67349249074 scopus 로고    scopus 로고
    • The multi-faceted basis of vitamin B12 (cobalamin) neurotrophism in adult central nervous system: Lessons learned from its deficiency
    • G. Scalabrino The multi-faceted basis of vitamin B12 (cobalamin) neurotrophism in adult central nervous system: lessons learned from its deficiency Prog. Neurobiol. 88 2009 203 220
    • (2009) Prog. Neurobiol. , vol.88 , pp. 203-220
    • Scalabrino, G.1
  • 17
    • 57649094924 scopus 로고    scopus 로고
    • Cobalamin-dependent and cobamide-dependent methyltransferases
    • R.G. Matthews, M. Koutmos, and S. Datta Cobalamin-dependent and cobamide-dependent methyltransferases Curr. Opin. Struct. Biol. 18 2008 658 666
    • (2008) Curr. Opin. Struct. Biol. , vol.18 , pp. 658-666
    • Matthews, R.G.1    Koutmos, M.2    Datta, S.3
  • 18
    • 0030829339 scopus 로고    scopus 로고
    • Cobalamin-dependent methionine synthase is a modular protein with distinct regions for binding homocysteine, methyltetrahydrofolate, cobalamin, and adenosylmethionine
    • C.W. Goulding, D. Postigo, and R.G. Matthews Cobalamin-dependent methionine synthase is a modular protein with distinct regions for binding homocysteine, methyltetrahydrofolate, cobalamin, and adenosylmethionine Biochemistry 36 1997 8082 8091
    • (1997) Biochemistry , vol.36 , pp. 8082-8091
    • Goulding, C.W.1    Postigo, D.2    Matthews, R.G.3
  • 19
    • 0027445612 scopus 로고
    • Assignment of enzymatic function to specific protein regions of cobalamin-dependent methionine synthase from Escherichia coli
    • J.T. Drummond, S. Huang, R.M. Blumenthal, and R.G. Matthews Assignment of enzymatic function to specific protein regions of cobalamin-dependent methionine synthase from Escherichia coli Biochemistry 32 1993 9290 9295
    • (1993) Biochemistry , vol.32 , pp. 9290-9295
    • Drummond, J.T.1    Huang, S.2    Blumenthal, R.M.3    Matthews, R.G.4
  • 20
    • 0035929601 scopus 로고    scopus 로고
    • Human methionine synthase reductase, a soluble P-450 reductase-like dual flavoprotein, is sufficient for NADPH-dependent methionine synthase activation
    • H. Olteanu, and R. Banerjee Human methionine synthase reductase, a soluble P-450 reductase-like dual flavoprotein, is sufficient for NADPH-dependent methionine synthase activation J. Biol. Chem. 276 2001 35558 35563
    • (2001) J. Biol. Chem. , vol.276 , pp. 35558-35563
    • Olteanu, H.1    Banerjee, R.2
  • 21
    • 33745438017 scopus 로고    scopus 로고
    • Human methionine synthase reductase is a molecular chaperone for human methionine synthase
    • K. Yamada, R.A. Gravel, T. Toraya, and R.G. Matthews Human methionine synthase reductase is a molecular chaperone for human methionine synthase Proc. Natl. Acad. Sci. U. S. A. 103 2006 9476 9481
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 9476-9481
    • Yamada, K.1    Gravel, R.A.2    Toraya, T.3    Matthews, R.G.4
  • 25
    • 0025425429 scopus 로고
    • The transport of vitamin B12 through polarized monolayers of Caco-2 cells
    • C.J. Dix, I.F. Hassan, H.Y. Obray, and G. Wilson The transport of vitamin B12 through polarized monolayers of Caco-2 cells Gastroenterology 98 1990 1272 1279
    • (1990) Gastroenterology , vol.98 , pp. 1272-1279
    • Dix, C.J.1    Hassan, I.F.2    Obray, H.Y.3    Wilson, G.4
  • 26
    • 0033642793 scopus 로고    scopus 로고
    • Transcytosis and coenzymatic conversion of [(57)Co]cobalamin bound to either endogenous transcobalamin II or exogenous intrinsic factor in caco-2 cells
    • L. Pons, M. Guy, D. Lambert, R. Hatier, and J.L. Guéant Transcytosis and coenzymatic conversion of [(57)Co]cobalamin bound to either endogenous transcobalamin II or exogenous intrinsic factor in caco-2 cells Cell. Physiol. Biochem. 10 2000 135 148
    • (2000) Cell. Physiol. Biochem. , vol.10 , pp. 135-148
    • Pons, L.1    Guy, M.2    Lambert, D.3    Hatier, R.4    Guéant, J.L.5
  • 27
    • 3142673339 scopus 로고    scopus 로고
    • Vitamin B12 deficiency as a worldwide problem
    • S.P. Stabler, and R.H. Allen Vitamin B12 deficiency as a worldwide problem Annu. Rev. Nutr. 24 2004 299 326
    • (2004) Annu. Rev. Nutr. , vol.24 , pp. 299-326
    • Stabler, S.P.1    Allen, R.H.2
  • 28
    • 84861231512 scopus 로고    scopus 로고
    • Fetal programming: Maternal nutrition and role of one-carbon metabolism
    • C.S. Yajnik, and U.S. Deshmukh Fetal programming: maternal nutrition and role of one-carbon metabolism Rev. Endocr. Metab. Disord. 13 2012 121 127
    • (2012) Rev. Endocr. Metab. Disord. , vol.13 , pp. 121-127
    • Yajnik, C.S.1    Deshmukh, U.S.2
  • 29
    • 48249126469 scopus 로고    scopus 로고
    • Public health significance of elevated homocysteine
    • J. Selhub Public health significance of elevated homocysteine Food Nutr. Bull. 29 2008 S116 S125
    • (2008) Food Nutr. Bull. , vol.29
    • Selhub, J.1
  • 30
    • 48249091668 scopus 로고    scopus 로고
    • The worldwide challenge of the dementias: A role for B vitamins and homocysteine?
    • A.D. Smith The worldwide challenge of the dementias: a role for B vitamins and homocysteine? Food Nutr. Bull. 29 2008 S143 S172
    • (2008) Food Nutr. Bull. , vol.29
    • Smith, A.D.1
  • 31
    • 0016590480 scopus 로고
    • Vitamin B12 metabolism in the fruit bat (Rousettus aegyptiacus). The induction of vitamin B12 deficiency and its effect on folate levels
    • S.V. Van Tonder, J. Metz, and R. Green Vitamin B12 metabolism in the fruit bat (Rousettus aegyptiacus). The induction of vitamin B12 deficiency and its effect on folate levels Br. J. Nutr. 34 1975 397 410
    • (1975) Br. J. Nutr. , vol.34 , pp. 397-410
    • Van Tonder, S.V.1    Metz, J.2    Green, R.3
  • 32
    • 0026735941 scopus 로고
    • Cobalamin deficiency and the pathogenesis of nervous system disease
    • J. Metz Cobalamin deficiency and the pathogenesis of nervous system disease Annu. Rev. Nutr. 12 1992 59 79
    • (1992) Annu. Rev. Nutr. , vol.12 , pp. 59-79
    • Metz, J.1
  • 34
    • 58549095250 scopus 로고    scopus 로고
    • Vitamin B deficiency causes neural cell loss and cognitive impairment in the developing rat
    • J.L. Daval, S. Blaise, and J.L. Guéant Vitamin B deficiency causes neural cell loss and cognitive impairment in the developing rat Proc. Natl. Acad. Sci. U. S. A. 106 2009 E1
    • (2009) Proc. Natl. Acad. Sci. U. S. A. , vol.106 , pp. 1
    • Daval, J.L.1    Blaise, S.2    Guéant, J.L.3
  • 36
    • 77953109648 scopus 로고    scopus 로고
    • Conditioning-like brief neonatal hypoxia improves cognitive function and brain tissue properties with marked gender dimorphism in adult rats
    • N. Martin, G. Pourié, C. Bossenmeyer-Pourié, R. Jazi, J.L. Guéant, P. Vert, and J.L. Daval Conditioning-like brief neonatal hypoxia improves cognitive function and brain tissue properties with marked gender dimorphism in adult rats Semin. Perinatol. 34 2010 193 200
    • (2010) Semin. Perinatol. , vol.34 , pp. 193-200
    • Martin, N.1    Pourié, G.2    Bossenmeyer-Pourié, C.3    Jazi, R.4    Guéant, J.L.5    Vert, P.6    Daval, J.L.7
  • 38
    • 61449182656 scopus 로고    scopus 로고
    • Fetal dilated cardiomyopathy: An unsuspected presentation of methylmalonic aciduria and hyperhomocystinuria, cblC type
    • I. De Bie, S.D. Nizard, and G.A. Mitchell Fetal dilated cardiomyopathy: an unsuspected presentation of methylmalonic aciduria and hyperhomocystinuria, cblC type Prenat. Diagn. 29 2009 266 270
    • (2009) Prenat. Diagn. , vol.29 , pp. 266-270
    • De Bie, I.1    Nizard, S.D.2    Mitchell, G.A.3
  • 39
    • 34250323543 scopus 로고    scopus 로고
    • Left ventricular systolic dysfunction is an independent predictor of homocysteine in angiographically documented patients with or without coronary artery lesions
    • R.M. Gueant-Rodriguez, Y. Juilliere, M. Nippert, I. Abdelmouttaleb, B. Herbeth, E. Aliot, N. Danchin, and J.L. Gueant Left ventricular systolic dysfunction is an independent predictor of homocysteine in angiographically documented patients with or without coronary artery lesions J. Thromb. Haemost. 5 2007 1209 1216
    • (2007) J. Thromb. Haemost. , vol.5 , pp. 1209-1216
    • Gueant-Rodriguez, R.M.1    Juilliere, Y.2    Nippert, M.3    Abdelmouttaleb, I.4    Herbeth, B.5    Aliot, E.6    Danchin, N.7    Gueant, J.L.8
  • 40
    • 36849065319 scopus 로고    scopus 로고
    • Homocysteine, brain natriuretic peptide and chronic heart failure: A critical review
    • W. Herrmann, M. Herrmann, J. Joseph, and S.C. Tyagi Homocysteine, brain natriuretic peptide and chronic heart failure: a critical review Clin. Chem. Lab. Med. 45 2007 1633 1644
    • (2007) Clin. Chem. Lab. Med. , vol.45 , pp. 1633-1644
    • Herrmann, W.1    Herrmann, M.2    Joseph, J.3    Tyagi, S.C.4
  • 42
    • 0026720833 scopus 로고
    • A congenital anomaly of vitamin B12 metabolism: A study of three cases
    • P. Russo, J. Doyon, E. Sonsino, H. Ogier, and J.M. Saudubray A congenital anomaly of vitamin B12 metabolism: a study of three cases Hum. Pathol. 23 1992 504 512
    • (1992) Hum. Pathol. , vol.23 , pp. 504-512
    • Russo, P.1    Doyon, J.2    Sonsino, E.3    Ogier, H.4    Saudubray, J.M.5
  • 43
    • 84856716045 scopus 로고    scopus 로고
    • Association between serum vitamin B12 levels and the degree of steatosis in patients with nonalcoholic fatty liver disease
    • M. Koplay, E. Gulcan, and F. Ozkan Association between serum vitamin B12 levels and the degree of steatosis in patients with nonalcoholic fatty liver disease J. Investig. Med. 59 2011 1137 1140
    • (2011) J. Investig. Med. , vol.59 , pp. 1137-1140
    • Koplay, M.1    Gulcan, E.2    Ozkan, F.3
  • 46
    • 0029829455 scopus 로고    scopus 로고
    • Increased hepatocyte CYP2E1 expression in a rat nutritional model of hepatic steatosis with inflammation
    • M.D. Weltman, G.C. Farrell, and C. Liddle Increased hepatocyte CYP2E1 expression in a rat nutritional model of hepatic steatosis with inflammation Gastroenterology 111 1996 1645 1653
    • (1996) Gastroenterology , vol.111 , pp. 1645-1653
    • Weltman, M.D.1    Farrell, G.C.2    Liddle, C.3
  • 47
    • 2342644813 scopus 로고    scopus 로고
    • Administration of the potent PPARalpha agonist, Wy-14,643, reverses nutritional fibrosis and steatohepatitis in mice
    • E. Ip, G. Farrell, P. Hall, G. Robertson, and I. Leclercq Administration of the potent PPARalpha agonist, Wy-14,643, reverses nutritional fibrosis and steatohepatitis in mice Hepatology 39 2004 1286 1296
    • (2004) Hepatology , vol.39 , pp. 1286-1296
    • Ip, E.1    Farrell, G.2    Hall, P.3    Robertson, G.4    Leclercq, I.5
  • 49
    • 40849083460 scopus 로고    scopus 로고
    • Non-alcoholic fatty liver disease: The mist gradually clears
    • N.M. de Alwis, and C.P. Day Non-alcoholic fatty liver disease: the mist gradually clears J. Hepatol. 48 2008 S104 S112
    • (2008) J. Hepatol. , vol.48
    • De Alwis, N.M.1    Day, C.P.2
  • 50
    • 84857287862 scopus 로고    scopus 로고
    • Fetal programming and metabolic syndrome
    • P. Rinaudo, and E. Wang Fetal programming and metabolic syndrome Annu. Rev. Physiol. 2012 107 130
    • (2012) Annu. Rev. Physiol. , pp. 107-130
    • Rinaudo, P.1    Wang, E.2
  • 52
    • 79953210362 scopus 로고    scopus 로고
    • Regulation of PGC-1α, a nodal regulator of mitochondrial biogenesis
    • P.J. Fernandez-Marcos, and J. Auwerx Regulation of PGC-1α, a nodal regulator of mitochondrial biogenesis Am. J. Clin. Nutr. 93 2011 884S 990S
    • (2011) Am. J. Clin. Nutr. , vol.93
    • Fernandez-Marcos, P.J.1    Auwerx, J.2
  • 54
    • 81055137579 scopus 로고    scopus 로고
    • Low maternal vitamin B-12 status is associated with offspring insulin resistance regardless of antenatal micronutrient
    • C.P. Stewart, P. Christian, K.J. Schulze, M. Arguello, S.C. Leclerq, S.K. Khatry, and K.P. West Jr. Low maternal vitamin B-12 status is associated with offspring insulin resistance regardless of antenatal micronutrient J. Nutr. 141 2011 1912 1917
    • (2011) J. Nutr. , vol.141 , pp. 1912-1917
    • Stewart, C.P.1    Christian, P.2    Schulze, K.J.3    Arguello, M.4    Leclerq, S.C.5    Khatry, S.K.6    West, Jr.K.P.7
  • 55
    • 0014572201 scopus 로고
    • Vitamin B12 dependent methionine biosynthesis in cultured mammalian cells
    • J.H. Mangum, B.K. Murray, and J.A. North Vitamin B12 dependent methionine biosynthesis in cultured mammalian cells Biochemistry 8 1969 3496 3499
    • (1969) Biochemistry , vol.8 , pp. 3496-3499
    • Mangum, J.H.1    Murray, B.K.2    North, J.A.3
  • 56
    • 0036306460 scopus 로고    scopus 로고
    • Vitamin B12 stalls the 80s ribosomal complex on the hepatitis C internal ribosome entry site
    • S.S. Takyar, E.J. Gowans, and W.B. Lott Vitamin B12 stalls the 80s ribosomal complex on the hepatitis C internal ribosome entry site J. Mol. Biol. 319 2002 1 8
    • (2002) J. Mol. Biol. , vol.319 , pp. 1-8
    • Takyar, S.S.1    Gowans, E.J.2    Lott, W.B.3
  • 58
    • 84875844920 scopus 로고    scopus 로고
    • Vitamin B12 supplementation improves rates of sustained viral response in patients chronically infected with hepatitis C virus
    • (Epub ahead of print)
    • A. Rocco, D. Compare, P. Coccoli, C. Esposito, A. Di Spirito, A. Barbato, P. Strazzullo, and G. Nardone Vitamin B12 supplementation improves rates of sustained viral response in patients chronically infected with hepatitis C virus Gut 2012 (Epub ahead of print)
    • (2012) Gut
    • Rocco, A.1    Compare, D.2    Coccoli, P.3    Esposito, C.4    Di Spirito, A.5    Barbato, A.6    Strazzullo, P.7    Nardone, G.8
  • 59
    • 35848939204 scopus 로고    scopus 로고
    • Cobalamin potentiates vinblastine cytotoxicity through downregulation of mdr-1 gene expression in HepG2 cells
    • V. Marguerite, M. Beri-Dexheimer, S. Ortiou, J.L. Guéant, and M. Merten Cobalamin potentiates vinblastine cytotoxicity through downregulation of mdr-1 gene expression in HepG2 cells Cell. Physiol. Biochem. 20 2007 967 976
    • (2007) Cell. Physiol. Biochem. , vol.20 , pp. 967-976
    • Marguerite, V.1    Beri-Dexheimer, M.2    Ortiou, S.3    Guéant, J.L.4    Merten, M.5
  • 60
    • 84872283598 scopus 로고    scopus 로고
    • Phospholipase D activation mediates cobalamin-induced downregulation of multidrug resistance-1 gene and increase in sensitivity to vinblastine in HepG2 cells
    • 10.1016/j.biocel.2012.09.018 pii: S1357-2725(12)00329-9 (Epub ahead of print)
    • V. Marguerite, E. Gkikopoulou, J.M. Alberto, J.L. Guéant, and M. Merten Phospholipase D activation mediates cobalamin-induced downregulation of multidrug resistance-1 gene and increase in sensitivity to vinblastine in HepG2 cells Int. J. Biochem. Cell Biol. Sep 29 2012 10.1016/j.biocel.2012.09.018 pii: S1357-2725(12)00329-9 (Epub ahead of print)
    • (2012) Int. J. Biochem. Cell Biol.
    • Marguerite, V.1    Gkikopoulou, E.2    Alberto, J.M.3    Guéant, J.L.4    Merten, M.5
  • 61
    • 0029087132 scopus 로고
    • Ultrastructural study of intestinal lactase gene expression
    • J.N. Freund, B. Jost, I. Duluc, and G. Morel Ultrastructural study of intestinal lactase gene expression Biol. Cell 83 1995 211 217
    • (1995) Biol. Cell , vol.83 , pp. 211-217
    • Freund, J.N.1    Jost, B.2    Duluc, I.3    Morel, G.4


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