Using whole mount in situ hybridization to examine thyroid hormone deiodinase expression in embryonic and larval zebrafish: A tool for examining OH-BDE toxicity to early life stages

Aquatic Toxicology

Volumn 132-133, Issue , 2013, Pages 190-199

  Dong, Wu ^a   Macaulay, Laura J ^a   Kwok, Kevin W H ^a   Hinton, David E ^a   Stapleton, Heather M ^a  

^a DUKE UNIVERSITY   (United States)

Author keywords

Endocrine Disruptors; Flame Retardants; Gene Expression; Whole mount in situ hybridization; Zebrafish

Indexed keywords

DEIODINASE 1; DEIODINASE 2; DEIODINASE 3; FLAME RETARDANT; HYDROXYLATED BROMINATED DIPHENYL ETHER; ISOENZYME; MESSENGER RNA; POLYBROMINATED DIPHENYL ETHER; REGULATOR PROTEIN; THYROID HORMONE; UNCLASSIFIED DRUG;

EMBRYO; ENDOCRINE DISRUPTOR; FISH; GENE EXPRESSION; HORMONE; LARVA; PBDE; POLLUTION EFFECT; TOXICITY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN VENTRICLE; CONTROLLED STUDY; DEIODINASE 1 GENE; DEIODINASE 2 GENE; DEIODINASE 3 GENE; DEIODINASE GENE; DEVELOPMENTAL STAGE; DEVELOPMENTAL TOXICITY; EMBRYO; EMBRYOTOXICITY; ENZYME ACTIVITY; ENZYME INHIBITION; GENE ACTIVITY; GENE EXPRESSION REGULATION; GENE LOCATION; HORMONAL REGULATION; HYPOTHALAMUS HYPOPHYSIS SYSTEM; IN SITU HYBRIDIZATION; IN VIVO STUDY; LARVAL STAGE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATOR GENE; SOMITE; THYROID GLAND; TOXICITY TESTING; ZEBRA FISH;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYO, NONMAMMALIAN; FISH PROTEINS; GENE EXPRESSION REGULATION; IN SITU HYBRIDIZATION; IODIDE PEROXIDASE; LARVA; POLYBROMINATED BIPHENYLS; PROTEIN ISOFORMS; RNA, MESSENGER; WATER POLLUTANTS, CHEMICAL; ZEBRAFISH;

DANIO RERIO; MAMMALIA;

EID: 84875601807     PISSN: 0166445X     EISSN: 18791514     Source Type: Journal    
DOI: 10.1016/j.aquatox.2013.02.008     Document Type: Article

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