In vitro and in ovo effects of four brominated flame retardants on toxicity and hepatic mRNA expression in chicken embryos

Toxicology Letters

Volumn 207, Issue 1, 2011, Pages 25-33

  Egloff, Caroline ^a,b   Crump, Doug ^b   Chiu, Suzanne ^b   Manning, Gillian ^a,b   McLaren, Kristina K ^a   Cassone, Cristina G ^a,b   Letcher, Robert J ^b   Gauthier, Lewis T ^b   Kennedy, Sean W ^a,b  

^a UNIVERSITY OF OTTAWA   (Canada)

^b ENVIRONMENT CANADA   (Canada)

Author keywords

BEHTBP; BTBPE; Chicken; DBDPE; Flame retardant; HCDBCO; MRNA expression

Indexed keywords

1,2 BIS(2,4,6 TRIBROMOPHENOXY)ETHANE; BETA ACTIN; BIS(2 ETHYLHEXYL)TETRABROMOPHTHALATE; CYTOCHROME; CYTOCHROME P450 1A4; CYTOCHROME P450 1A5; CYTOCHROME P450 2H1; CYTOCHROME P450 3A37; DECABROMODIPHENYLETHANE; FLAME RETARDANT; HEXACHLOROCYCLOPENTADIENYLDIBROMOCYCLOOCTANE; MESSENGER RNA; PREALBUMIN; THYROXINE DEIODINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BIRD; CELL VIABILITY; CHICK EMBRYO; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; EMBRYO; GENE EXPRESSION; GENE TARGETING; GENETIC TRANSCRIPTION; IN VITRO STUDY; LIPID METABOLISM; LIVER CELL; LIVER CELL CULTURE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; THYROID HORMONE METABOLISM; TOXICITY TESTING; UPREGULATION; WILD ANIMAL; XENOBIOTIC METABOLISM;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; CELL SURVIVAL; CHICK EMBRYO; FLAME RETARDANTS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEPATOCYTES; IODIDE PEROXIDASE; LIVER; POLYBROMINATED BIPHENYLS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STATISTICS, NONPARAMETRIC;

AVES; SPONDIAS PURPUREA;

EID: 80052843777     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2011.08.015     Document Type: Article

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