Thyroid hormone receptors and type I iodothyronine 5′-deiodinase activity of human thyroid toxic adenomas and benign cold nodules

Experimental and Clinical Endocrinology and Diabetes

Volumn 110, Issue 4, 2002, Pages 166-170

  Brtko, J ^a   Bobalova J ^a   Podoba, J ^a   Schmutzler, C ^a   Köhrle, Josef ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Cold nodule; Electrophoretic mobility shift assay; Human thyroid; Thyroid hormone receptor; Toxic adenoma; Type I iodothyronine 5 deiodinase

Indexed keywords

THYROID HORMONE RECEPTOR; THYROTROPIN; THYROXINE DEIODINASE; IODIDE PEROXIDASE; ISOENZYME;

ARTICLE; CLONAL VARIATION; COMPLEX FORMATION; ELECTROPHORETIC MOBILITY; ENZYME ACTIVITY; HORMONE RESPONSE; HUMAN; HUMAN TISSUE; MEDIATOR RELEASE; PRIORITY JOURNAL; RECEPTOR GENE; SIGNAL TRANSDUCTION; THYROID ADENOMA; THYROID NODULE; TOXIC GOITER; ADENOMA; ADULT; AGED; FEMALE; MALE; METABOLISM; MIDDLE AGED; THYROID TUMOR; THYROTOXICOSIS;

ADENOMA; ADULT; AGED; FEMALE; HUMAN; IODIDE PEROXIDASE; ISOENZYMES; MALE; MIDDLE AGE; RECEPTORS, THYROID HORMONE; SUPPORT, NON-U.S. GOV'T; THYROID NEOPLASMS; THYROID NODULE; THYROTOXICOSIS; HUMANS; MIDDLE AGED;

EID: 0036016565     PISSN: 09477349     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2002-32147     Document Type: Article

References (22)

1. A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells
2. Hormone-nuclear receptor interactions in health and disease. The iodothyronine deiodinases and 5′-deiodination
3. Molecular aspects of the pathogenesis of nodular goiters, thyroid nodules and adenomas
4. 5α protein-adenylate cyclase pathway may not be sufficient to generate toxic adenomas
5. The steroid and thyroid hormone receptor superfamily
6. Molecular basis of thyroid cancer
7. Role of fibroblast growth factor in the pathogenesis of nodular goiter
8. Some new twists in the regulation of gene expression by thyroid hormone and retinoic acid receptors
9. Expression of functional stimulatory guanine nucleotide binding protein in non-functioning thyroid adenomas is not correlated to adenylate cyclase activity and growth of these tumors
10. The promoter of the human type I 5′-deiodinase gene: Mapping of the transcription start site and identification of a DR+4 thyroid-hormone responsive element
11. Type I 5′-deiodinase a marker for differentiated thyroid carcinoma?
12. Thyroid hormone deiodination in target tissues - A regulatory role for the trace element selenium?
13. Iodothyronine 5′-deiodinase from rat kidney: Substrate specificity and the 5′-deiodination of reverse triiodothyronine
14. Protein measurement with the Folin phenol reagent
15. Thyroid peroxidase activity in human nodular goiters
16. 2+ cascades
17. Enhanced functional activity in thyroid adenomas in vitro
18. Genetic basis of endocrine disease: Somatic and germline mutations of the TSH receptor gene in thyroid diseases
19. Functional retinoid and thyroid hormone receptors in human thyroid-carcinoma cell lines and tissues
20. Natural heterogeneity of thyroid cells: The basis for understanding thyroid function and nodular goiter growth
21. Cold follicles in a multinodular human goiter arise partly from a failing iodide pump and partly from deficient iodine organification
22. Thyroid peroxidase, thyroglobulin cAMP and DNA in human thyroid